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Search results 1 to 100 out of 1165 for Hprt1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
3251 | HPRT1
Type: gene
Organism: human
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Gene
394936 | hprt1
Type: gene
Organism: frog, western clawed
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Gene
24465 | Hprt1
Type: gene
Organism: rat
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Gene
442945 | HPRT1
Type: gene
Organism: dog, domestic
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Gene
735894 | HPRT1
Type: gene
Organism: chimpanzee
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Gene
281229 | HPRT1
Type: gene
Organism: cattle
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Gene
395653 | HPRT1
Type: gene
Organism: chicken
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Gene
406259 | hprt1
Type: gene
Organism: zebrafish
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Gene
709186 | HPRT1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:96217 | Hprt1
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
107032760 | LOC107032760
Type: gene
Organism: human
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Protein
Q6TDG6
Organism: Mus musculus/domesticus
Length: 51  
Fragment?: true
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Protein
Q99KF5
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
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Publication
18950699 | J:144244
First Author: Yang GS
Year: 2009
Journal: Genomics
Title: Next generation tools for high-throughput promoter and expression analysis employing single-copy knock-ins at the Hprt1 locus.
Volume: 93
Issue: 3
Pages: 196-204
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Publication
- | J:145689
     
First Author: The Pleiades Promoter Project
Year: 2009
Journal: MGI Direct Data Submission
Title: Generation of reporter and cre-expressing targeted transgenic mice in the Hprt1 gene using human MiniPromoters that drive region- and cell-specific gene expression in the mouse brain
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Publication
- | J:204202
     
First Author: The Pleiades Promoter and CanEuCre Project
Year: 2014
Journal: MGI Direct Data Submission
Title: Generation of reporter and cre-expressing targeted transgenic mice in the Hprt1 gene using human MiniPromoters that drive region- and cell-specific gene expression in the mouse brain
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Publication
38523431 | J:347672
First Author: Lanza DG
Year: 2024
Journal: Genesis
Title: An oocyte-specific Cas9-expressing mouse for germline CRISPR/Cas9-mediated genome editing.
Volume: 62
Issue: 2
Pages: e23589
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Publication
30565754 | J:273248
First Author: Groh J
Year: 2019
Journal: Glia
Title: Targeting microglia attenuates neuroinflammation-related neural damage in mice carrying human PLP1 mutations.
Volume: 67
Issue: 2
Pages: 277-290
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Publication
37903797 | J:342223
First Author: Groh J
Year: 2023
Journal: Nat Commun
Title: Microglia-mediated demyelination protects against CD8(+) T cell-driven axon degeneration in mice carrying PLP defects.
Volume: 14
Issue: 1
Pages: 6911
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Publication
28173160 | J:238644
First Author: Groh J
Year: 2016
Journal: Hum Mol Genet
Title: Pathogenic inflammation in the CNS of mice carrying human PLP1 mutations.
Volume: 25
Issue: 21
Pages: 4686-4702
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Publication
37182098 | J:337596
First Author: Abdelwahab T
Year: 2023
Journal: iScience
Title: Cytotoxic CNS-associated T cells drive axon degeneration by targeting perturbed oligodendrocytes in PLP1 mutant mice.
Volume: 26
Issue: 5
Pages: 106698
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Protein Coding Gene
MGP_CAROLIEiJ_G0033070 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035719 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96217 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036218 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034683 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035469 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035608 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036235 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034827 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031614 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034227 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
6294614 | J:20083
First Author: Konecki DS
Year: 1982
Journal: Nucleic Acids Res
Title: Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants.
Volume: 10
Issue: 21
Pages: 6763-75
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Publication
6326107 | J:20092
First Author: Melton DW
Year: 1984
Journal: Proc Natl Acad Sci U S A
Title: Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.
Volume: 81
Issue: 7
Pages: 2147-51
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Publication
3029599 | J:15485
First Author: Kuehn MR
Year: 1987
Journal: Nature
Title: A potential animal model for Lesch-Nyhan syndrome through introduction of HPRT mutations into mice.
Volume: 326
Issue: 6110
Pages: 295-8
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Publication
9886073 | J:51651
First Author: Jinnah HA
Year: 1999
Journal: J Neurochem
Title: Influence of age and strain on striatal dopamine loss in a genetic mouse model of Lesch-Nyhan disease.
Volume: 72
Issue: 1
Pages: 225-9
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Publication
1432691 | J:17905
First Author: Jinnah HA
Year: 1992
Journal: J Pharmacol Exp Ther
Title: Functional analysis of brain dopamine systems in a genetic mouse model of Lesch-Nyhan syndrome.
Volume: 263
Issue: 2
Pages: 596-607
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Publication
1528024 | J:3354
First Author: Williamson DJ
Year: 1992
Journal: J Inherit Metab Dis
Title: Mouse models of hypoxanthine phosphoribosyltransferase deficiency.
Volume: 15
Issue: 4
Pages: 665-73
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Publication
3221240 | J:115724
First Author: Finger S
Year: 1988
Journal: J Neurol Sci
Title: Behavioral and neurochemical evaluation of a transgenic mouse model of Lesch-Nyhan syndrome.
Volume: 86
Issue: 2-3
Pages: 203-13
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Publication
2292045 | J:2057
First Author: Jinnah HA
Year: 1990
Journal: Brain Res Bull
Title: Animal models of Lesch-Nyhan syndrome.
Volume: 25
Issue: 3
Pages: 467-75
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Publication
3821905 | J:15483
First Author: Hooper M
Year: 1987
Journal: Nature
Title: HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells.
Volume: 326
Issue: 6110
Pages: 292-5
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Publication
9205113 | J:41459
First Author: Tsuda H
Year: 1997
Journal: Genomics
Title: Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines.
Volume: 42
Issue: 3
Pages: 413-21
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Publication
17374562 | J:134847
First Author: Egami K
Year: 2007
Journal: Neurobiol Dis
Title: Basal ganglia dopamine loss due to defect in purine recycling.
Volume: 26
Issue: 2
Pages: 396-407
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Publication
21818316 | J:175856
First Author: Keebaugh AC
Year: 2011
Journal: PLoS One
Title: PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse.
Volume: 6
Issue: 7
Pages: e22381
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Publication
2912572 | J:161048
First Author: Thompson S
Year: 1989
Journal: Cell
Title: Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells.
Volume: 56
Issue: 2
Pages: 313-21
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Publication
11882343 | J:75479
First Author: Visser JE
Year: 2002
Journal: Brain Res Dev Brain Res
Title: Oxidative stress and dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Volume: 133
Issue: 2
Pages: 127-39
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Publication
11297820 | J:107966
First Author: Boer P
Year: 2001
Journal: Neurosci Lett
Title: Decelerated rate of dendrite outgrowth from dopaminergic neurons in primary cultures from brains of hypoxanthine phosphoribosyltransferase-deficient knockout mice.
Volume: 303
Issue: 1
Pages: 45-8
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Publication
26453761 | J:228653
 
First Author: Tschirner SK
Year: 2015
Journal: Neurosci Lett
Title: Altered histamine neurotransmission in HPRT-deficient mice.
Volume: 609
Pages: 74-80
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Publication
9413985 | J:44728
First Author: Ordway JM
Year: 1997
Journal: Cell
Title: Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.
Volume: 91
Issue: 6
Pages: 753-63
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Publication
22001673 | J:191414
First Author: Hacke K
Year: 2012
Journal: Exp Hematol
Title: Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow.
Volume: 40
Issue: 1
Pages: 3-13.e3
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Publication
29305058 | J:271791
 
First Author: Zizzo MG
Year: 2018
Journal: Auton Neurosci
Title: Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease.
Volume: 210
Pages: 55-64
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Publication
1451655 | J:2389
First Author: Moore TF
Year: 1992
Journal: Development
Title: Imprinting of phosphoribosyltransferases during preimplantation development of the mouse mutant, Hprtb-m3.
Volume: 115
Issue: 4
Pages: 1011-6
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Publication
7509865 | J:17798
First Author: Jinnah HA
Year: 1994
Journal: J Neurosci
Title: Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Volume: 14
Issue: 3 Pt 1
Pages: 1164-75
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Publication
15908225 | J:102545
First Author: Mikolaenko I
Year: 2005
Journal: Neurobiol Dis
Title: A Golgi study of neuronal architecture in a genetic mouse model for Lesch-Nyhan disease.
Volume: 20
Issue: 2
Pages: 479-90
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Publication
23340293 | J:202087
First Author: Kamiyama H
Year: 2013
Journal: Clin Cancer Res
Title: Personalized chemotherapy profiling using cancer cell lines from selectable mice.
Volume: 19
Issue: 5
Pages: 1139-46
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Publication
28282408 | J:246011
First Author: Zennaro C
Year: 2017
Journal: PLoS One
Title: The renal phenotype of allopurinol-treated HPRT-deficient mouse.
Volume: 12
Issue: 3
Pages: e0173512
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Publication
19912847 | J:2058
First Author: Jinnah HA
Year: 1992
Journal: Mol Cell Neurosci
Title: Localization of hypoxanthine-guanine phosphoribosyltransferase mRNA in the mouse brain by in situ hybridization.
Volume: 3
Issue: 1
Pages: 64-78
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Publication
10037486 | J:53129
First Author: Pelled D
Year: 1999
Journal: J Neurochem
Title: Abnormal purine and pyrimidine nucleotide content in primary astroglia cultures from hypoxanthine-guanine phosphoribosyltransferase-deficient transgenic mice.
Volume: 72
Issue: 3
Pages: 1139-45
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Publication
11892008 | J:75826
First Author: Tang SH
Year: 2002
Journal: Genesis
Title: A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ.
Volume: 32
Issue: 3
Pages: 199-202
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Publication
12562513 | J:81778
First Author: Le Y
Year: 2003
Journal: J Neurochem
Title: Far-upstream elements are dispensable for tissue-specific proenkephalin expression using a Cre-mediated knock-in strategy.
Volume: 84
Issue: 4
Pages: 689-97
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Publication
20807748 | J:164356
First Author: Portales-Casamar E
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A regulatory toolbox of MiniPromoters to drive selective expression in the brain.
Volume: 107
Issue: 38
Pages: 16589-94
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Publication
18395839 | J:144541
First Author: Luchman HA
Year: 2008
Journal: Genesis
Title: Temporally controlled prostate epithelium-specific gene alterations.
Volume: 46
Issue: 4
Pages: 229-34
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Publication
16135087 | J:129784
First Author: Jenkins BG
Year: 2005
Journal: J Neurochem
Title: Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease.
Volume: 95
Issue: 2
Pages: 553-62
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Publication
21184801 | J:170585
First Author: Hatada S
Year: 2011
Journal: Exp Hematol
Title: Therapeutic benefits in thalassemic mice transplanted with long-term-cultured bone marrow cells.
Volume: 39
Issue: 3
Pages: 375-83, 383.e1-4
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Publication
27081293 | J:353122
 
First Author: Harrison TA
Year: 2016
Journal: Mol Vis
Title: Corneal endothelial cells possess an elaborate multipolar shape to maximize the basolateral to apical membrane area.
Volume: 22
Pages: 31-9
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Publication
37445982 | J:337955
 
First Author: Toejing P
Year: 2023
Journal: Int J Mol Sci
Title: Accelerated Bone Loss in Transgenic Mice Expressing Constitutively Active TGF-β Receptor Type I.
Volume: 24
Issue: 13
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Publication
22549942 | J:218887
First Author: Duran J
Year: 2012
Journal: EMBO Mol Med
Title: Deleterious effects of neuronal accumulation of glycogen in flies and mice.
Volume: 4
Issue: 8
Pages: 719-29
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Publication
24413155 | J:229300
First Author: LeBlanc AC
Year: 2014
Journal: Cell Death Differ
Title: Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment.
Volume: 21
Issue: 5
Pages: 696-706
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Publication
20947725 | J:166063
First Author: Rad R
Year: 2010
Journal: Science
Title: PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.
Volume: 330
Issue: 6007
Pages: 1104-7
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Publication
19064922 | J:166283
First Author: Su Q
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A DNA transposon-based approach to validate oncogenic mutations in the mouse.
Volume: 105
Issue: 50
Pages: 19904-9
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Publication
22916024 | J:188125
First Author: Fragoso R
Year: 2012
Journal: PLoS Genet
Title: Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1.
Volume: 8
Issue: 8
Pages: e1002855
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Publication
24622775 | J:213660
First Author: Clarke SE
Year: 2014
Journal: Transgenic Res
Title: The iFat1 transgene permits conditional endogenous n-3 PUFA enrichment both in vitro and in vivo.
Volume: 23
Issue: 3
Pages: 489-501
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Publication
19141541 | J:157969
First Author: Palais G
Year: 2009
Journal: Physiol Genomics
Title: Targeted transgenesis at the HPRT locus: an efficient strategy to achieve tightly controlled in vivo conditional expression with the tet system.
Volume: 37
Issue: 2
Pages: 140-6
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Publication
24167246 | J:202901
First Author: Ramms L
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Keratins as the main component for the mechanical integrity of keratinocytes.
Volume: 110
Issue: 46
Pages: 18513-8
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Publication
37672574 | J:342873
First Author: Liao J
Year: 2023
Journal: Sci Adv
Title: Establishment of paternal methylation imprint at the H19/Igf2 imprinting control region.
Volume: 9
Issue: 36
Pages: eadi2050
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Publication
26872257 | J:232341
First Author: Arbogast T
Year: 2016
Journal: PLoS Genet
Title: Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes.
Volume: 12
Issue: 2
Pages: e1005709
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Publication
30043519 | J:266870
First Author: McGann JC
Year: 2018
Journal: Glia
Title: Neuronal activity induces glutathione metabolism gene expression in astrocytes.
Volume: 66
Issue: 9
Pages: 2024-2039
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Publication
24794428 | J:210018
First Author: Portmann T
Year: 2014
Journal: Cell Rep
Title: Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome.
Volume: 7
Issue: 4
Pages: 1077-1092
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Publication
17868096 | J:124702
First Author: Muzumdar MD
Year: 2007
Journal: Genesis
Title: A global double-fluorescent Cre reporter mouse.
Volume: 45
Issue: 9
Pages: 593-605
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Publication
37731543 | J:340747
 
First Author: Cao Y
Year: 2023
Journal: Front Physiol
Title: CD51 labels periosteal injury-responsive osteoprogenitors.
Volume: 14
Pages: 1231352
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Publication
33253931 | J:313732
 
First Author: Hrdlicka HC
Year: 2021
Journal: Bone
Title: Inhibition of miR-29-3p isoforms via tough decoy suppresses osteoblast function in homeostasis but promotes intermittent parathyroid hormone-induced bone anabolism.
Volume: 143
Pages: 115779
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Publication
22479386 | J:181830
First Author: Tasic B
Year: 2012
Journal: PLoS One
Title: Extensions of MADM (mosaic analysis with double markers) in mice.
Volume: 7
Issue: 3
Pages: e33332
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Publication
31214184 | J:284425
 
First Author: Hose M
Year: 2019
Journal: Front Immunol
Title: T Cell-Specific Overexpression of Acid Sphingomyelinase Results in Elevated T Cell Activation and Reduced Parasitemia During Plasmodium yoelii Infection.
Volume: 10
Pages: 1225
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Publication
21926270 | J:189486
First Author: Thorel F
Year: 2011
Journal: Diabetes
Title: Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice.
Volume: 60
Issue: 11
Pages: 2872-82
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Publication
20484117 | J:185411
First Author: Zhang SY
Year: 2010
Journal: Sci Signal
Title: c-mip impairs podocyte proximal signaling and induces heavy proteinuria.
Volume: 3
Issue: 122
Pages: ra39
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Publication
15265883 | J:92020
First Author: Magness ST
Year: 2004
Journal: J Immunol
Title: In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse.
Volume: 173
Issue: 3
Pages: 1561-70
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Publication
22096518 | J:180977
First Author: Platt B
Year: 2011
Journal: PLoS One
Title: Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1.
Volume: 6
Issue: 11
Pages: e27068
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Publication
19738070 | J:152682
First Author: Cadieux C
Year: 2009
Journal: Cancer Res
Title: Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types.
Volume: 69
Issue: 18
Pages: 7188-97
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Publication
20980682 | J:168401
First Author: Liu J
Year: 2011
Journal: Blood
Title: Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle.
Volume: 117
Issue: 1
Pages: 342-51
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Publication
26239174 | J:232259
First Author: Jyoti A
Year: 2015
Journal: Neurobiol Aging
Title: Progressive age-related changes in sleep and EEG profiles in the PLB1Triple mouse model of Alzheimer's disease.
Volume: 36
Issue: 10
Pages: 2768-84
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Publication
8790342 | J:81859
First Author: Kirby SL
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
Volume: 93
Issue: 18
Pages: 9402-7
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Publication
24270544 | J:206843
First Author: Hackl MJ
Year: 2013
Journal: Nat Med
Title: Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags.
Volume: 19
Issue: 12
Pages: 1661-6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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