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Search results 1 to 100 out of 721 for Hspg2

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0.021s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:7587795
Assay Type: RNA in situ
Annotation Date: 2024-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7587814
Age: embryonic day 13.0
Image: 1C Hspg2
Note: Authors report apical polarization of expression.
Specimen Label: 1C Hspg2
Detected: true
Specimen Num: 1
Publication
First Author: Gerdes Gyuricza I
Year: 2020
Journal: Eur J Hum Genet
Title: Is HSPG2 a modifier gene for Marfan syndrome?
Volume: 28
Issue: 9
Pages: 1292-1296
Protein
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
Publication
First Author: Hayes AJ
Year: 2013
Journal: Histochem Cell Biol
Title: Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc.
Volume: 139
Issue: 1
Pages: 1-11
Publication
First Author: Shu CC
Year: 2019
Journal: Biochem J
Title: Elevated hypertrophy, growth plate maturation, glycosaminoglycan deposition, and exostosis formation in the Hspg2 exon 3 null mouse intervertebral disc.
Volume: 476
Issue: 2
Pages: 225-243
Protein
Organism: Mus musculus/domesticus
Length: 834  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1100  
Fragment?: true
Strain
Attribute String: mutant stock, targeted mutation
Publication
First Author: Rodgers KD
Year: 2007
Journal: Hum Mol Genet
Title: Reduced perlecan in mice results in chondrodysplasia resembling Schwartz-Jampel syndrome.
Volume: 16
Issue: 5
Pages: 515-28
Publication
First Author: Nakamura K
Year: 2019
Journal: J Cell Biol
Title: Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.
Volume: 218
Issue: 10
Pages: 3506-3525
Publication
First Author: Arikawa-Hirasawa E
Year: 2001
Journal: Nat Genet
Title: Dyssegmental dysplasia, Silverman-Handmaker type, is caused by functional null mutations of the perlecan gene.
Volume: 27
Issue: 4
Pages: 431-4
Publication  
First Author: Hayes AJ
Year: 2016
Journal: Eur Cell Mater
Title: Pericellular colocalisation and interactive properties of type VI collagen and perlecan in the intervertebral disc.
Volume: 32
Pages: 40-57
Publication  
First Author: Shu CC
Year: 2018
Journal: PeerJ
Title: Achilles and tail tendons of perlecan exon 3 null heparan sulphate deficient mice display surprising improvement in tendon tensile properties and altered collagen fibril organisation compared to C57BL/6 wild type mice.
Volume: 6
Pages: e5120
Publication
First Author: Tsiantoulas D
Year: 2021
Journal: Nature
Title: APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Volume: 597
Issue: 7874
Pages: 92-96
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Noonan DM
Year: 1988
Journal: J Biol Chem
Title: Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan.
Volume: 263
Issue: 31
Pages: 16379-87
Publication  
First Author: Ning L
Year: 2015
Journal: Matrix Biol
Title: Perlecan inhibits autophagy to maintain muscle homeostasis in mouse soleus muscle.
Volume: 48
Pages: 26-35
Publication
First Author: Gotha L
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury.
Volume: 307
Issue: 3
Pages: H337-45
Publication
First Author: Tran-Lundmark K
Year: 2008
Journal: Circ Res
Title: Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation.
Volume: 103
Issue: 1
Pages: 43-52
Publication
First Author: Shu CC
Year: 2016
Journal: Arthritis Rheumatol
Title: Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis.
Volume: 68
Issue: 4
Pages: 868-79
Publication  
First Author: Gubbiotti MA
Year: 2017
Journal: Matrix Biol
Title: A current view of perlecan in physiology and pathology: A mosaic of functions.
Volume: 57-58
Pages: 285-298
Publication
First Author: Tran PK
Year: 2004
Journal: Circ Res
Title: Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan.
Volume: 94
Issue: 4
Pages: 550-8
Publication
First Author: Wang B
Year: 2014
Journal: J Bone Miner Res
Title: Perlecan-containing pericellular matrix regulates solute transport and mechanosensing within the osteocyte lacunar-canalicular system.
Volume: 29
Issue: 4
Pages: 878-91
Publication  
First Author: Pei S
Year: 2020
Journal: Bone
Title: Perlecan/Hspg2 deficiency impairs bone's calcium signaling and associated transcriptome in response to mechanical loading.
Volume: 131
Pages: 115078
Publication
First Author: Kvist AJ
Year: 2006
Journal: J Biol Chem
Title: Chondroitin sulfate perlecan enhances collagen fibril formation. Implications for perlecan chondrodysplasias.
Volume: 281
Issue: 44
Pages: 33127-39
Publication
First Author: Bangratz M
Year: 2012
Journal: Am J Pathol
Title: A mouse model of Schwartz-Jampel syndrome reveals myelinating Schwann cell dysfunction with persistent axonal depolarization in vitro and distal peripheral nerve hyperexcitability when perlecan is lacking.
Volume: 180
Issue: 5
Pages: 2040-55
Publication
First Author: Xu X
Year: 2016
Journal: Dev Biol
Title: Knockdown of the pericellular matrix molecule perlecan lowers in situ cell and matrix stiffness in developing cartilage.
Volume: 418
Issue: 2
Pages: 242-7
Publication
First Author: Yamashita Y
Year: 2018
Journal: Sci Rep
Title: Perlecan, a heparan sulfate proteoglycan, regulates systemic metabolism with dynamic changes in adipose tissue and skeletal muscle.
Volume: 8
Issue: 1
Pages: 7766
Publication
First Author: Kaneko H
Year: 2013
Journal: Matrix Biol
Title: Synovial perlecan is required for osteophyte formation in knee osteoarthritis.
Volume: 32
Issue: 3-4
Pages: 178-87
Publication
First Author: Inomata T
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Perlecan-deficient mutation impairs corneal epithelial structure.
Volume: 53
Issue: 3
Pages: 1277-84
Publication
First Author: Xu Z
Year: 2010
Journal: Matrix Biol
Title: Perlecan deficiency causes muscle hypertrophy, a decrease in myostatin expression, and changes in muscle fiber composition.
Volume: 29
Issue: 6
Pages: 461-70
Publication
First Author: Ida-Yonemochi H
Year: 2005
Journal: J Histochem Cytochem
Title: Perlecan, a basement membrane-type heparan sulfate proteoglycan, in the enamel organ: its intraepithelial localization in the stellate reticulum.
Volume: 53
Issue: 6
Pages: 763-72
Publication
First Author: Hart M
Year: 2001
Journal: J Pathol
Title: Overproduction of perlecan core protein in cultured cells and transgenic mice.
Volume: 194
Issue: 2
Pages: 262-9
Publication
First Author: Olsen BR
Year: 1999
Journal: J Cell Biol
Title: Life without perlecan has its problems.
Volume: 147
Issue: 5
Pages: 909-12
Publication
First Author: Tapanadechopone P
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Localization of glycosaminoglycan substitution sites on domain V of mouse perlecan.
Volume: 265
Issue: 3
Pages: 680-90
Publication
First Author: Ledbetter SR
Year: 1985
Journal: J Biol Chem
Title: Identification of the precursor protein to basement membrane heparan sulfate proteoglycans.
Volume: 260
Issue: 13
Pages: 8106-113
Publication
First Author: Kallunki P
Year: 1991
Journal: Genomics
Title: Cloning of human heparan sulfate proteoglycan core protein, assignment of the gene (HSPG2) to 1p36.1----p35 and identification of a BamHI restriction fragment length polymorphism.
Volume: 11
Issue: 2
Pages: 389-96
Publication
First Author: Ailles L
Year: 1993
Journal: Lab Invest
Title: Induction of perlecan gene expression precedes amyloid formation during experimental murine AA amyloidogenesis.
Volume: 69
Issue: 4
Pages: 443-8
Publication  
First Author: Iozzo RV
Year: 1994
Journal: Biochem J
Title: The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices.
Volume: 302 ( Pt 3)
Pages: 625-39
Publication
First Author: Costell M
Year: 1996
Journal: FEBS Lett
Title: Structural characterization of recombinant domain II of the basement membrane proteoglycan perlecan.
Volume: 396
Issue: 2-3
Pages: 127-31
Publication
First Author: Joseph SJ
Year: 1996
Journal: Development
Title: A proteoglycan that activates fibroblast growth factors during early neuronal development is a perlecan variant.
Volume: 122
Issue: 11
Pages: 3443-52
Publication
First Author: Handler M
Year: 1997
Journal: Dev Dyn
Title: Developmental expression of perlecan during murine embryogenesis.
Volume: 210
Issue: 2
Pages: 130-45
Publication  
First Author: Parajuli A
Year: 2020
Journal: Biomolecules
Title: Trabecular Bone Deficit and Enhanced Anabolic Response to Re-Ambulation after Disuse in Perlecan-Deficient Skeleton.
Volume: 10
Issue: 2
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1742828
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 26
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 27
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 28
GXD Expression    
Probe: MGI:1204351
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1788628
Stage: TS28
Assay Id: MGI:1204353
Age: postnatal week 6-8
Image: st96_133
Specimen Label: None
Detected: true
Specimen Num: 29