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Search results 1 to 100 out of 428 for Idh2

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0.063s
Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Strain
Attribute String: strain family
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:3724826
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826180
Age: embryonic day 14.5
Image: Additional file 4 Idh2
Specimen Label: Additional file 4 Idh2
Detected: true
Specimen Num: 1
Gene
Type: gene
Organism: human
Publication  
First Author: Wang H
Year: 2023
Journal: Metabolism
Title: Hepatic IDH2 regulates glycolysis and gluconeogenesis.
Volume: 143
Pages: 155559
Publication
First Author: Kats LM
Year: 2014
Journal: Cell Stem Cell
Title: Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance.
Volume: 14
Issue: 3
Pages: 329-41
Publication
First Author: Lee SJ
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Idh2 deficiency accelerates renal dysfunction in aged mice.
Volume: 493
Issue: 1
Pages: 34-39
Publication  
First Author: Ku HJ
Year: 2015
Journal: Free Radic Biol Med
Title: IDH2 deficiency promotes mitochondrial dysfunction and cardiac hypertrophy in mice.
Volume: 80
Pages: 84-92
Publication  
First Author: Park JH
Year: 2018
Journal: Redox Biol
Title: IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis.
Volume: 17
Pages: 16-24
Publication
First Author: White K
Year: 2018
Journal: Sci Rep
Title: Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice.
Volume: 8
Issue: 1
Pages: 5039
Publication
First Author: Zhang X
Year: 2020
Journal: Blood
Title: Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis.
Volume: 135
Issue: 11
Pages: 845-856
Publication
First Author: Kim SH
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: IDH2 deficiency impairs cutaneous wound healing via ROS-dependent apoptosis.
Volume: 1865
Issue: 11
Pages: 165523
Publication
First Author: Kim H
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: IDH2 deficiency exacerbates acetaminophen hepatotoxicity in mice via mitochondrial dysfunction-induced apoptosis.
Volume: 1865
Issue: 9
Pages: 2333-2341
Publication  
First Author: Lee SH
Year: 2019
Journal: Bone
Title: IDH2 deficiency increases bone mass with reduced osteoclastogenesis by limiting RANKL expression in osteoblasts.
Volume: 129
Pages: 115056
Publication
First Author: Park JH
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Disruption of IDH2 attenuates lipopolysaccharide-induced inflammation and lung injury in an α-ketoglutarate-dependent manner.
Volume: 503
Issue: 2
Pages: 798-802
Publication
First Author: Gong F
Year: 2019
Journal: Biochem Biophys Res Commun
Title: IDH2 protects against nonalcoholic steatohepatitis by alleviating dyslipidemia regulated by oxidative stress.
Volume: 514
Issue: 3
Pages: 593-600
Publication  
First Author: Pan JH
Year: 2020
Journal: Int J Mol Sci
Title: IDH2 Deficiency Is Critical in Myogenesis and Fatty Acid Metabolism in Mice Skeletal Muscle.
Volume: 21
Issue: 16
Publication
First Author: Chen TC
Year: 2022
Journal: Oncogene
Title: Oncogenesis induced by combined Phf6 and Idh2 mutations through increased oncometabolites and impaired DNA repair.
Volume: 41
Issue: 11
Pages: 1576-1588
Publication
First Author: Leca J
Year: 2023
Journal: Cancer Cell
Title: IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment.
Volume: 41
Issue: 2
Pages: 323-339.e10
Publication
First Author: Lemonnier F
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
Volume: 113
Issue: 52
Pages: 15084-15089
Publication  
First Author: Han YK
Year: 2021
Journal: Redox Biol
Title: Oxidative stress following acute kidney injury causes disruption of lung cell cilia and their release into the bronchoaveolar lavage fluid and lung injury, which are exacerbated by Idh2 deletion.
Volume: 46
Pages: 102077
Publication
First Author: Chae U
Year: 2018
Journal: Physiol Res
Title: IDH2-deficient mice develop spinal deformities with aging.
Volume: 67
Issue: 3
Pages: 487-494
Publication  
First Author: Lee SJ
Year: 2016
Journal: Free Radic Biol Med
Title: Increased obesity resistance and insulin sensitivity in mice lacking the isocitrate dehydrogenase 2 gene.
Volume: 99
Pages: 179-188
Publication
First Author: Han SJ
Year: 2017
Journal: J Am Soc Nephrol
Title: Mitochondrial NADP+-Dependent Isocitrate Dehydrogenase Deficiency Exacerbates Mitochondrial and Cell Damage after Kidney Ischemia-Reperfusion Injury.
Volume: 28
Issue: 4
Pages: 1200-1215
Publication
First Author: Choi SJ
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Isocitrate dehydrogenase 2 deficiency induces endothelial inflammation via p66sh-mediated mitochondrial oxidative stress.
Volume: 503
Issue: 3
Pages: 1805-1811
Publication  
First Author: Cha H
Year: 2017
Journal: Redox Biol
Title: Increased susceptibility of IDH2-deficient mice to dextran sodium sulfate-induced colitis.
Volume: 13
Pages: 32-38
Publication  
First Author: Pan JH
Year: 2019
Journal: Genes (Basel)
Title: Hepatic Transcriptomics Reveals that Lipogenesis Is a Key Signaling Pathway in Isocitrate Dehydrogenase 2 Deficient Mice.
Volume: 10
Issue: 9
Publication
First Author: Kim S
Year: 2022
Journal: Commun Biol
Title: miR204 potentially promotes non-alcoholic fatty liver disease by inhibition of cpt1a in mouse hepatocytes.
Volume: 5
Issue: 1
Pages: 1002
Publication
First Author: Karlstaedt A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart.
Volume: 113
Issue: 37
Pages: 10436-41
Publication
First Author: Fortin J
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells.
Volume: 120
Issue: 4
Pages: e2208176120
Publication
First Author: Ku HJ
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Isocitrate dehydrogenase 2 deficiency exacerbates dermis damage by ultraviolet-B via ΔNp63 downregulation.
Volume: 1864
Issue: 4 Pt A
Pages: 1138-1147
Publication
First Author: Savoia M
Year: 2019
Journal: FASEB J
Title: P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation.
Volume: 33
Issue: 3
Pages: 4107-4123
Publication
First Author: Shih AH
Year: 2017
Journal: Cancer Discov
Title: Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Volume: 7
Issue: 5
Pages: 494-505
Publication
First Author: Chae U
Year: 2019
Journal: Aging (Albany NY)
Title: Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions.
Volume: 11
Issue: 17
Pages: 7242-7256
Publication
First Author: Yoshimi A
Year: 2019
Journal: Nature
Title: Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis.
Volume: 574
Issue: 7777
Pages: 273-277
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Jo SH
Year: 2001
Journal: J Biol Chem
Title: Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+-dependent isocitrate dehydrogenase.
Volume: 276
Issue: 19
Pages: 16168-76
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Not Specified
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Specimen Num: 11
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1742828
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 26
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 27
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 28
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1788628
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 29
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1789128
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 30
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1885228
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 31
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1866628
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 32
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 33
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 34
GXD Expression    
Probe: MGI:1205299
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3515128
Stage: TS28
Assay Id: MGI:1205301
Age: postnatal week 6-8
Image: st96_457
Specimen Label: None
Detected: true
Specimen Num: 35