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Search results 1 to 100 out of 254 for Il21

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0.108s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wichner K
Year: 2016
Journal: FASEB J
Title: Dysregulated development of IL-17- and IL-21-expressing follicular helper T cells and increased germinal center formation in the absence of RORγt.
Volume: 30
Issue: 2
Pages: 761-74
Gene
Type: gene
Organism: Homo sapiens
Allele
Name: transgene insertion G, Martin Lipp
Allele Type: Transgenic
Attribute String: Recombinase
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
MGI Directed Relationship Property
Name: Non-mouse_Gene_Symbol
Value: IL21
MGI Directed Relationship Property
Name: Non-mouse_Gene_Symbol
Value: IL21
Publication
First Author: Allard EL
Year: 2007
Journal: Eur J Immunol
Title: Overexpression of IL-21 promotes massive CD8+ memory T cell accumulation.
Volume: 37
Issue: 11
Pages: 3069-77
Publication
First Author: Parrish-Novak J
Year: 2000
Journal: Nature
Title: Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.
Volume: 408
Issue: 6808
Pages: 57-63
Publication
First Author: Koh CH
Year: 2020
Journal: Cancer Immunol Res
Title: GITR Agonism Triggers Antitumor Immune Responses through IL21-Expressing Follicular Helper T Cells.
Volume: 8
Issue: 5
Pages: 698-709
Protein
Organism: Mus musculus
Length: 146  
Fragment?: false
Publication
First Author: Stumhofer JS
Year: 2013
Journal: PLoS One
Title: IL-21 is required for optimal antibody production and T cell responses during chronic Toxoplasma gondii infection.
Volume: 8
Issue: 5
Pages: e62889
Publication
First Author: Chen G
Year: 2010
Journal: J Immunol
Title: Regulation of the IL-21 gene by the NF-κB transcription factor c-Rel.
Volume: 185
Issue: 4
Pages: 2350-9
Publication
First Author: Wei L
Year: 2007
Journal: J Biol Chem
Title: IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner.
Volume: 282
Issue: 48
Pages: 34605-10
Publication
First Author: Lüthje K
Year: 2012
Journal: Nat Immunol
Title: The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.
Volume: 13
Issue: 5
Pages: 491-8
Publication  
First Author: Allred MG
Year: 2021
Journal: Int J Mol Sci
Title: Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice.
Volume: 22
Issue: 7
Publication
First Author: McGuire HM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus.
Volume: 106
Issue: 46
Pages: 19438-43
Publication
First Author: Liu SM
Year: 2011
Journal: J Clin Invest
Title: Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice.
Volume: 121
Issue: 11
Pages: 4303-10
Publication
First Author: Végran F
Year: 2014
Journal: Nat Immunol
Title: The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells.
Volume: 15
Issue: 8
Pages: 758-66
Publication
First Author: Pérez-Mazliah D
Year: 2015
Journal: PLoS Pathog
Title: Disruption of IL-21 signaling affects T cell-B cell interactions and abrogates protective humoral immunity to malaria.
Volume: 11
Issue: 3
Pages: e1004715
Publication
First Author: Hsu CY
Year: 2018
Journal: J Clin Invest
Title: SUMO-defective c-Maf preferentially transactivates Il21 to exacerbate autoimmune diabetes.
Volume: 128
Issue: 9
Pages: 3779-3793
Publication
First Author: Harada Y
Year: 2012
Journal: Immunity
Title: The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells.
Volume: 36
Issue: 2
Pages: 188-200
Publication  
First Author: Ikegami H
Year: 2003
Journal: Ann N Y Acad Sci
Title: Congenic mapping and candidate sequencing of susceptibility genes for Type 1 diabetes in the NOD mouse.
Volume: 1005
Pages: 196-204
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Chen XL
Year: 2013
Journal: Clin Exp Immunol
Title: Induction of autoimmune diabetes in non-obese diabetic mice requires interleukin-21-dependent activation of autoreactive CD8⁺ T cells.
Volume: 173
Issue: 2
Pages: 184-94
Publication
First Author: Mariño E
Year: 2012
Journal: Diabetes
Title: B-cell cross-presentation of autologous antigen precipitates diabetes.
Volume: 61
Issue: 11
Pages: 2893-905
Publication
First Author: Lin PY
Year: 2015
Journal: Immunology
Title: Interleukin-21 suppresses the differentiation and functions of T helper 2 cells.
Volume: 144
Issue: 4
Pages: 668-76
Publication
First Author: Clough LE
Year: 2008
Journal: J Immunol
Title: Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21.
Volume: 180
Issue: 8
Pages: 5393-401
Publication
First Author: Ozaki K
Year: 2004
Journal: J Immunol
Title: Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6.
Volume: 173
Issue: 9
Pages: 5361-71
Publication
First Author: Clarkson BD
Year: 2014
Journal: J Exp Med
Title: T cell-derived interleukin (IL)-21 promotes brain injury following stroke in mice.
Volume: 211
Issue: 4
Pages: 595-604
Publication
First Author: Carbo A
Year: 2014
Journal: MBio
Title: Systems modeling of the role of interleukin-21 in the maintenance of effector CD4+ T cell responses during chronic Helicobacter pylori infection.
Volume: 5
Issue: 4
Pages: e01243-14
Publication  
First Author: Yasmin S
Year: 2019
Journal: Infect Immun
Title: Interleukin-21 (IL-21) Downregulates Dendritic Cell Cytokine Responses to Helicobacter pylori and Modulates T Lymphocyte IL-17A Expression in Peyer's Patches during Infection.
Volume: 87
Issue: 11
Publication
First Author: Fabrizi M
Year: 2014
Journal: Diabetes
Title: IL-21 is a major negative regulator of IRF4-dependent lipolysis affecting Tregs in adipose tissue and systemic insulin sensitivity.
Volume: 63
Issue: 6
Pages: 2086-96
Publication
First Author: Fantini MC
Year: 2007
Journal: Eur J Immunol
Title: IL-21 regulates experimental colitis by modulating the balance between Treg and Th17 cells.
Volume: 37
Issue: 11
Pages: 3155-63
Publication
First Author: Stolfi C
Year: 2011
Journal: J Exp Med
Title: Involvement of interleukin-21 in the regulation of colitis-associated colon cancer.
Volume: 208
Issue: 11
Pages: 2279-90
Publication
First Author: Suto A
Year: 2002
Journal: Blood
Title: Interleukin 21 prevents antigen-induced IgE production by inhibiting germ line C(epsilon) transcription of IL-4-stimulated B cells.
Volume: 100
Issue: 13
Pages: 4565-73
Publication
First Author: Moroz A
Year: 2004
Journal: J Immunol
Title: IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: comparative evaluation of IL-2, IL-15, and IL-21.
Volume: 173
Issue: 2
Pages: 900-9
Publication
First Author: Pelletier M
Year: 2004
Journal: J Immunol
Title: In vivo and in vitro roles of IL-21 in inflammation.
Volume: 173
Issue: 12
Pages: 7521-30
Publication
First Author: Ostiguy V
Year: 2007
Journal: J Leukoc Biol
Title: IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade.
Volume: 82
Issue: 3
Pages: 645-56
Publication
First Author: D'Alise AM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors.
Volume: 105
Issue: 50
Pages: 19857-62
Publication
First Author: Castermans K
Year: 2008
Journal: Blood
Title: Angiostatic activity of the antitumor cytokine interleukin-21.
Volume: 112
Issue: 13
Pages: 4940-7
Publication
First Author: Coquet JM
Year: 2007
Journal: J Immunol
Title: IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production.
Volume: 178
Issue: 5
Pages: 2827-34
Publication
First Author: Magari M
Year: 2011
Journal: J Immunol
Title: IL-21-dependent B cell death driven by prostaglandin E2, a product secreted from follicular dendritic cells.
Volume: 187
Issue: 8
Pages: 4210-8
Publication
First Author: Huang X
Year: 2020
Journal: J Immunol
Title: IL-21 Promotes Intestinal Memory IgA Responses.
Volume: 205
Issue: 7
Pages: 1944-1952
Publication
First Author: Yuan Y
Year: 2017
Journal: JCI Insight
Title: IL-21 is required for CD4 memory formation in response to viral infection.
Volume: 2
Issue: 7
Pages: e90652
Publication  
First Author: Noguchi N
Year: 2018
Journal: Infect Immun
Title: Interleukin-21 Induces Short-Lived Effector CD8+ T Cells but Does Not Inhibit Their Exhaustion after Mycobacterium bovis BCG Infection in Mice.
Volume: 86
Issue: 8
Publication
First Author: Phares TW
Year: 2013
Journal: J Neuroimmunol
Title: IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis.
Volume: 263
Issue: 1-2
Pages: 43-54
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691618
Age: postnatal adult
Image: UC Davis_1888028
Note: vas deferens
Specimen Label: UC Davis_1888028
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691618
Age: postnatal adult
Image: UC Davis_1888026
Specimen Label: UC Davis_1888026
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691618
Age: postnatal adult
Image: UC Davis_1888027
Specimen Label: UC Davis_1888027
Detected: true
Specimen Num: 2
Publication
First Author: Kasaian MT
Year: 2002
Journal: Immunity
Title: IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity.
Volume: 16
Issue: 4
Pages: 559-69
Publication
First Author: Lee Y
Year: 2015
Journal: J Clin Invest
Title: IL-21R signaling is critical for induction of spontaneous experimental autoimmune encephalomyelitis.
Volume: 125
Issue: 11
Pages: 4011-20
Publication
First Author: King IL
Year: 2011
Journal: Nat Immunol
Title: Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner.
Volume: 13
Issue: 1
Pages: 44-50
Publication
First Author: Søndergaard H
Year: 2009
Journal: J Immunol
Title: Endogenous IL-21 restricts CD8+ T cell expansion and is not required for tumor immunity.
Volume: 183
Issue: 11
Pages: 7326-36
Publication
First Author: Ramanathan S
Year: 2011
Journal: J Immunol
Title: Exposure to IL-15 and IL-21 enables autoreactive CD8 T cells to respond to weak antigens and cause disease in a mouse model of autoimmune diabetes.
Volume: 186
Issue: 9
Pages: 5131-41
Publication
First Author: Spolski R
Year: 2012
Journal: J Immunol
Title: IL-21 promotes the pathologic immune response to pneumovirus infection.
Volume: 188
Issue: 4
Pages: 1924-32
Publication
First Author: Haymaker C
Year: 2017
Journal: Nat Commun
Title: Absence of Grail promotes CD8+ T cell anti-tumour activity.
Volume: 8
Issue: 1
Pages: 239
Publication
First Author: Coquet JM
Year: 2015
Journal: Immunity
Title: Interleukin-21-Producing CD4(+) T Cells Promote Type 2 Immunity to House Dust Mites.
Volume: 43
Issue: 2
Pages: 318-30
Publication
First Author: Coquet JM
Year: 2008
Journal: J Immunol
Title: Cutting edge: IL-21 is not essential for Th17 differentiation or experimental autoimmune encephalomyelitis.
Volume: 180
Issue: 11
Pages: 7097-101
Publication
First Author: Linterman MA
Year: 2009
Journal: J Exp Med
Title: Follicular helper T cells are required for systemic autoimmunity.
Volume: 206
Issue: 3
Pages: 561-76
Publication
First Author: McGuire HM
Year: 2011
Journal: Diabetes
Title: Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models.
Volume: 60
Issue: 3
Pages: 867-75
Publication
First Author: Vogelzang A
Year: 2008
Journal: Immunity
Title: A fundamental role for interleukin-21 in the generation of T follicular helper cells.
Volume: 29
Issue: 1
Pages: 127-37
Publication
First Author: Nguyen V
Year: 2012
Journal: J Immunol
Title: IL-21 promotes lupus-like disease in chronic graft-versus-host disease through both CD4 T cell- and B cell-intrinsic mechanisms.
Volume: 189
Issue: 2
Pages: 1081-93
Publication
First Author: Sutherland AP
Year: 2009
Journal: Diabetes
Title: Interleukin-21 is required for the development of type 1 diabetes in NOD mice.
Volume: 58
Issue: 5
Pages: 1144-55
Publication
First Author: Jain S
Year: 2015
Journal: Am J Pathol
Title: IL-21-driven neoplasms in SJL mice mimic some key features of human angioimmunoblastic T-cell lymphoma.
Volume: 185
Issue: 11
Pages: 3102-14
Publication
First Author: Rasheed MA
Year: 2013
Journal: J Virol
Title: Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells.
Volume: 87
Issue: 13
Pages: 7737-46
Publication
First Author: King IL
Year: 2010
Journal: J Immunol
Title: A nonredundant role for IL-21 receptor signaling in plasma cell differentiation and protective type 2 immunity against gastrointestinal helminth infection.
Volume: 185
Issue: 10
Pages: 6138-45
Publication
First Author: Dorfmeier CL
Year: 2013
Journal: PLoS Negl Trop Dis
Title: Investigating the role for IL-21 in rabies virus vaccine-induced immunity.
Volume: 7
Issue: 3
Pages: e2129
Publication
First Author: Datta S
Year: 2008
Journal: PLoS One
Title: IL-21 limits peripheral lymphocyte numbers through T cell homeostatic mechanisms.
Volume: 3
Issue: 9
Pages: e3118
Publication
First Author: Seo GY
Year: 2009
Journal: J Leukoc Biol
Title: IL-21 ensures TGF-beta 1-induced IgA isotype expression in mouse Peyer's patches.
Volume: 85
Issue: 5
Pages: 744-50
Publication
First Author: Odegard JM
Year: 2008
Journal: J Exp Med
Title: ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity.
Volume: 205
Issue: 12
Pages: 2873-86
Publication
First Author: Herber D
Year: 2007
Journal: J Immunol
Title: IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.
Volume: 178
Issue: 6
Pages: 3822-30
Publication
First Author: Publicover J
Year: 2011
Journal: J Clin Invest
Title: IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B.
Volume: 121
Issue: 3
Pages: 1154-62
Publication
First Author: Rahman M
Year: 2007
Journal: FEBS Lett
Title: Cloning and characterization of an isoform of interleukin-21.
Volume: 581
Issue: 21
Pages: 4001-9
Publication
First Author: Choi SC
Year: 2018
Journal: J Immunol
Title: Relative Contributions of B Cells and Dendritic Cells from Lupus-Prone Mice to CD4+ T Cell Polarization.
Volume: 200
Issue: 9
Pages: 3087-3099
Publication
First Author: Dienz O
Year: 2009
Journal: J Exp Med
Title: The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
Volume: 206
Issue: 1
Pages: 69-78
Publication
First Author: Sheikh AA
Year: 2019
Journal: Cell Rep
Title: Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection.
Volume: 28
Issue: 7
Pages: 1758-1772.e4
Publication
First Author: Kishida T
Year: 2007
Journal: J Immunol
Title: IL-21 induces inhibitor of differentiation 2 and leads to complete abrogation of anaphylaxis in mice.
Volume: 179
Issue: 12
Pages: 8554-61
Publication
First Author: Inoue SI
Year: 2018
Journal: Immunology
Title: γδ T cells modulate humoral immunity against Plasmodium berghei infection.
Volume: 155
Issue: 4
Pages: 519-532