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Search results 1 to 100 out of 441 for Il22

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
50616 | IL22
Type: gene
Organism: human
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Gene
100216308 | il22
Type: gene
Organism: frog, western clawed
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Gene
500836 | Il22
Type: gene
Organism: rat
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Gene
741423 | IL22
Type: gene
Organism: chimpanzee
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Gene
481153 | IL22
Type: gene
Organism: dog, domestic
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Gene
507778 | IL22
Type: gene
Organism: cattle
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Gene
417838 | IL22
Type: gene
Organism: chicken
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Gene
553964 | il22
Type: gene
Organism: zebrafish
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Gene
718047 | IL22
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1355307 | Il22
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2022-07-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3542328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7314332
Age: postnatal day 7
Image: S2 DF IL22 KO
Note: Similar as in the wild-type.
Specimen Label: S2 DF IL22 KO
Detected: true
Specimen Num: 2
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CL Term
CL:4301571 | DCO Il22 Gly-Gaba_1 cerebellar neuron (Mmus)
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Publication
29764837 | J:318887
First Author: Khosravi N
Year: 2018
Journal: Cancer Immunol Res
Title: IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties.
Volume: 6
Issue: 7
Pages: 788-797
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Publication
32330729 | J:329476
First Author: Zhang A
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: A Central Role for Lipocalin-2 in the Adaptation to Short-Bowel Syndrome Through Down-Regulation of IL22 in Mice.
Volume: 10
Issue: 2
Pages: 309-326
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CL Term
CL:4300348 | DCO Il22 Gly-Gaba cerebellar neuron (Mmus)
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CL Term
CL:4301573 | DCO Il22 Gly-Gaba_3 cerebellar neuron (Mmus)
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CL Term
CL:4306992 | DCO Il22 Gly-Gaba_2 cerebellar neuron (Mmus)
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Publication
38697116 | J:349452
First Author: Liu C
Year: 2024
Journal: Immunity
Title: A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification.
Volume: 57
Issue: 5
Pages: 1005-1018.e7
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Publication
25261485 | J:220074
First Author: Ahlfors H
Year: 2014
Journal: J Immunol
Title: IL-22 fate reporter reveals origin and control of IL-22 production in homeostasis and infection.
Volume: 193
Issue: 9
Pages: 4602-13
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Publication
35304419 | J:324700
First Author: Gershater M
Year: 2022
Journal: J Immunol
Title: IL-22 Plays a Dual Role in the Amniotic Cavity: Tissue Injury and Host Defense against Microbes in Preterm Labor.
Volume: 208
Issue: 7
Pages: 1595-1615
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Publication
33488580 | J:335336
 
First Author: Jing X
Year: 2020
Journal: Front Immunol
Title: IL-23 Contributes to Campylobacter jejuni-Induced Intestinal Pathology via Promoting IL-17 and IFN? Responses by Innate Lymphoid Cells.
Volume: 11
Pages: 579615
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Publication
36871955 | J:364697
First Author: Kouno T
Year: 2023
Journal: Alcohol Clin Exp Res (Hoboken)
Title: Engineered bacteria producing aryl-hydrocarbon receptor agonists protect against ethanol-induced liver disease in mice.
Volume: 47
Issue: 5
Pages: 856-867
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Publication
33443222 | J:300027
 
First Author: Wang Q
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22.
Volume: 118
Issue: 1
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Publication
40892518 | J:377544
 
First Author: Bowman CJ
Year: 2025
Journal: J Clin Invest
Title: A20's linear ubiquitin-binding motif restrains pathogenic activation of Th17 cells and IL-22-driven enteritis.
Volume: 135
Issue: 17
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Publication
33446526 | J:300010
 
First Author: Break TJ
Year: 2021
Journal: Science
Title: Aberrant type 1 immunity drives susceptibility to mucosal fungal infections.
Volume: 371
Issue: 6526
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Publication
30449315 | J:272652
First Author: Teng Y
Year: 2018
Journal: Cell Host Microbe
Title: Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota.
Volume: 24
Issue: 5
Pages: 637-652.e8
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Publication
40905825 | J:377463
First Author: Griffith BD
Year: 2026
Journal: Cancer Discov
Title: Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization.
Volume: 16
Issue: 1
Pages: 114-134
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Publication
29315356 | J:349627
First Author: Dambaeva S
Year: 2018
Journal: Biol Reprod
Title: Interleukin 22 prevents lipopolysaccharide- induced preterm labor in mice.
Volume: 98
Issue: 3
Pages: 299-308
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Publication
23596287 | J:198457
First Author: Ivanov S
Year: 2013
Journal: J Virol
Title: Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection.
Volume: 87
Issue: 12
Pages: 6911-24
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Publication
28942919 | J:252193
First Author: Kadoki M
Year: 2017
Journal: Cell
Title: Organism-Level Analysis of Vaccination Reveals Networks of Protection across Tissues.
Volume: 171
Issue: 2
Pages: 398-413.e21
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Publication
24412612 | J:209395
First Author: Guo X
Year: 2014
Journal: Immunity
Title: Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection.
Volume: 40
Issue: 1
Pages: 25-39
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Publication
29248460 | J:258008
First Author: Albertsson AM
Year: 2018
Journal: Am J Pathol
Title: ?? T Cells Contribute to Injury in the Developing Brain.
Volume: 188
Issue: 3
Pages: 757-767
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Publication
33513946 | J:338626
 
First Author: Park HJ
Year: 2021
Journal: Int J Mol Sci
Title: CD1d-Dependent iNKT Cells Control DSS-Induced Colitis in a Mouse Model of IFN?-Mediated Hyperinflammation by Increasing IL22-Secreting ILC3 Cells.
Volume: 22
Issue: 3
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Publication
30816423 | J:378247
First Author: Zhang X
Year: 2019
Journal: Int J Mol Med
Title: Interleukin?22 regulates the homeostasis of the intestinal epithelium during inflammation.
Volume: 43
Issue: 4
Pages: 1657-1668
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Publication
29907867 | J:375399
First Author: Reeder KM
Year: 2018
Journal: Mucosal Immunol
Title: The common ?-chain cytokine IL-7 promotes immunopathogenesis during fungal asthma.
Volume: 11
Issue: 5
Pages: 1352-1362
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Publication
29621481 | J:275541
First Author: Geng H
Year: 2018
Journal: Gastroenterology
Title: In Inflamed Intestinal Tissues and Epithelial Cells, Interleukin 22?Signaling Increases Expression of H19 Long Noncoding RNA, Which Promotes Mucosal Regeneration.
Volume: 155
Issue: 1
Pages: 144-155
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Publication
36630913 | J:336225
First Author: Briukhovetska D
Year: 2023
Journal: Immunity
Title: T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis.
Volume: 56
Issue: 1
Pages: 143-161.e11
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Publication
35263568 | J:324836
First Author: Zindl CL
Year: 2022
Journal: Immunity
Title: A nonredundant role for T?cell-derived interleukin 22 in antibacterial defense of colonic crypts.
Volume: 55
Issue: 3
Pages: 494-511.e11
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Publication
32154791 | J:328871
First Author: Kim EY
Year: 2020
Journal: J Clin Invest
Title: Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-? in NK cells.
Volume: 130
Issue: 6
Pages: 3238-3252
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Publication
30858342 | J:370911
 
First Author: Zhang T
Year: 2019
Journal: Infect Immun
Title: The Plasmid-Encoded pGP3 Promotes Chlamydia Evasion of Acidic Barriers in Both Stomach and Vagina.
Volume: 87
Issue: 5
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Publication
38054920 | J:367904
First Author: Taguchi K
Year: 2024
Journal: Kidney Int
Title: IL-22 is secreted by proximal tubule cells and regulates DNA damage response and cell death in?acute kidney injury.
Volume: 105
Issue: 1
Pages: 99-114
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Publication
35340206 | J:322892
 
First Author: Wang Y
Year: 2022
Journal: Oxid Med Cell Longev
Title: Interleukin-22 Deficiency Reduces Angiotensin II-Induced Aortic Dissection and Abdominal Aortic Aneurysm in ApoE-/- Mice.
Volume: 2022
Pages: 7555492
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Publication
33737460 | J:323336
 
First Author: Sullivan ZA
Year: 2021
Journal: Science
Title: ?? T cells regulate the intestinal response to nutrient sensing.
Volume: 371
Issue: 6535
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Publication
36810248 | J:352291
 
First Author: Spalinger MR
Year: 2023
Journal: JCI Insight
Title: PTPN2 regulates bacterial clearance in a mouse model of enteropathogenic and enterohemorrhagic E. coli infection.
Volume: 8
Issue: 4
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Publication
32901017 | J:338010
First Author: Yang W
Year: 2020
Journal: Nat Commun
Title: Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity.
Volume: 11
Issue: 1
Pages: 4457
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Publication
34195684 | J:321566
First Author: Mihi B
Year: 2021
Journal: Cell Rep Med
Title: Interleukin-22 signaling attenuates necrotizing enterocolitis by promoting epithelial cell regeneration.
Volume: 2
Issue: 6
Pages: 100320
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Publication
26455347 | J:246257
First Author: McDermott AJ
Year: 2016
Journal: Immunology
Title: Interleukin-23 (IL-23), independent of IL-17 and IL-22, drives neutrophil recruitment and innate inflammation during Clostridium difficile colitis in mice.
Volume: 147
Issue: 1
Pages: 114-24
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Publication
25327211 | J:246261
First Author: Sadighi Akha AA
Year: 2015
Journal: Immunology
Title: Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice.
Volume: 144
Issue: 4
Pages: 587-97
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Publication
39644894 | J:360368
First Author: Xia M
Year: 2025
Journal: Immunity
Title: Elevated IL-22 as a result of stress-induced gut leakage suppresses septal neuron activation to ameliorate anxiety-like behavior.
Volume: 58
Issue: 1
Pages: 218-231.e12
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Publication
30104211 | J:375400
 
First Author: Reeder KM
Year: 2018
Journal: Infect Immun
Title: Role of Common ?-Chain Cytokines in Lung Interleukin-22 Regulation after Acute Exposure to Aspergillus fumigatus.
Volume: 86
Issue: 10
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Publication
40478733 | J:377850
First Author: Li P
Year: 2025
Journal: Cell Rep
Title: ROR?t is crucial for gut homeostasis by regulating the expression of HB-EGF rather than IL-22 in activated ILC3s.
Volume: 44
Issue: 6
Pages: 115793
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Publication
29109123 | J:252646
First Author: Kleinschmidt D
Year: 2017
Journal: J Immunol
Title: A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury.
Volume: 199
Issue: 12
Pages: 4078-4090
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Publication
31132747 | J:286073
 
First Author: Shindo R
Year: 2019
Journal: iScience
Title: Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis.
Volume: 15
Pages: 536-551
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Publication
41066556 | J:373127
First Author: Gao Y
Year: 2025
Journal: Science
Title: T cell cholesterol transport links intestinal immune responses to dietary lipid absorption.
Volume: 390
Issue: 6769
Pages: eadt4169
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Publication
22546855 | J:188299
First Author: Pantelyushin S
Year: 2012
Journal: J Clin Invest
Title: Ror?t+ innate lymphocytes and ?? T cells initiate psoriasiform plaque formation in mice.
Volume: 122
Issue: 6
Pages: 2252-6
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Publication
42236988 | J:390153
First Author: Suzuki M
Year: 2026
Journal: Nat Microbiol
Title: IL-22 promotes genesis of small intestinal secretory cells that protect against cholera in mice.
Volume: 11
Issue: 7
Pages: 1949-1966
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Publication
10657629 | J:60655
First Author: Dumoutier L
Year: 2000
Journal: J Immunol
Title: Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9.
Volume: 164
Issue: 4
Pages: 1814-9
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Publication
26261005 | J:273159
First Author: Grasberger H
Year: 2015
Journal: Gastroenterology
Title: Increased Expression of DUOX2 Is an Epithelial Response to?Mucosal Dysbiosis Required for Immune Homeostasis in?Mouse Intestine.
Volume: 149
Issue: 7
Pages: 1849-59
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Publication
30962403 | J:290297
 
First Author: Lin H
Year: 2019
Journal: Infect Immun
Title: Antigen-Specific CD4(+) T Cell-Derived Gamma Interferon Is Both Necessary and Sufficient for Clearing Chlamydia from the Small Intestine but Not the Large Intestine.
Volume: 87
Issue: 6
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Publication
23853597 | J:213365
First Author: De Luca A
Year: 2013
Journal: PLoS Pathog
Title: IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis.
Volume: 9
Issue: 7
Pages: e1003486
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Publication
31843590 | J:291952
First Author: Perusina Lanfranca M
Year: 2020
Journal: Gastroenterology
Title: Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice.
Volume: 158
Issue: 5
Pages: 1417-1432.e11
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Publication
35176228 | J:322757
First Author: Leonardi I
Year: 2022
Journal: Cell
Title: Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity.
Volume: 185
Issue: 5
Pages: 831-846.e14
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Publication
34853467 | J:339261
First Author: Grigg JB
Year: 2021
Journal: Nature
Title: Antigen-presenting innate lymphoid cells orchestrate neuroinflammation.
Volume: 600
Issue: 7890
Pages: 707-712
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Publication
41034585 | J:372794
First Author: Chi F
Year: 2025
Journal: Nature
Title: Dietary cysteine enhances intestinal stemness via CD8(+) T cell-derived IL-22.
Volume: 647
Issue: 8090
Pages: 706-715
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Publication
37726288 | J:340765
First Author: Beppu AK
Year: 2023
Journal: Nat Commun
Title: Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection.
Volume: 14
Issue: 1
Pages: 5814
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Protein Coding Gene
MGP_129S1SvImJ_G0017766 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1355307 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017599 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018200 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_SPRETEiJ_G0016664 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
23690441 | J:201007
First Author: Mielke LA
Year: 2013
Journal: J Exp Med
Title: Retinoic acid expression associates with enhanced IL-22 production by ?? T cells and innate lymphoid cells and attenuation of intestinal inflammation.
Volume: 210
Issue: 6
Pages: 1117-24
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Publication
25254361 | J:222502
First Author: Fang P
Year: 2014
Journal: PLoS One
Title: Immune modulatory effects of IL-22 on allergen-induced pulmonary inflammation.
Volume: 9
Issue: 9
Pages: e107454
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Publication
20220096 | J:160050
First Author: Wilson MS
Year: 2010
Journal: J Immunol
Title: Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections.
Volume: 184
Issue: 8
Pages: 4378-90
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Publication
32580124 | J:350017
First Author: Das S
Year: 2020
Journal: iScience
Title: Interleukin-22 Inhibits Respiratory Syncytial Virus Production by Blocking Virus-Mediated Subversion of Cellular Autophagy.
Volume: 23
Issue: 7
Pages: 101256
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Publication
23490254 | J:195347
First Author: Pociask DA
Year: 2013
Journal: Am J Pathol
Title: IL-22 is essential for lung epithelial repair following influenza infection.
Volume: 182
Issue: 4
Pages: 1286-96
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Publication
25568302 | J:230915
First Author: Wallace DF
Year: 2015
Journal: Int Immunol
Title: Analysis of IL-22 contribution to hepcidin induction and hypoferremia during the response to LPS in vivo.
Volume: 27
Issue: 6
Pages: 281-7
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Publication
28607133 | J:244752
First Author: Dudakov JA
Year: 2017
Journal: Blood
Title: Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease.
Volume: 130
Issue: 7
Pages: 933-942
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Publication
26285207 | J:242878
First Author: Gimblet C
Year: 2015
Journal: PLoS One
Title: IL-22 Protects against Tissue Damage during Cutaneous Leishmaniasis.
Volume: 10
Issue: 8
Pages: e0134698
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Publication
28051088 | J:265002
First Author: Ji YW
Year: 2017
Journal: Mucosal Immunol
Title: Lacrimal gland-derived IL-22 regulates IL-17-mediated ocular mucosal inflammation.
Volume: 10
Issue: 5
Pages: 1202-1210
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Publication
31080013 | J:294410
 
First Author: Mattapallil MJ
Year: 2019
Journal: J Autoimmun
Title: Interleukin 22 ameliorates neuropathology and protects from central nervous system autoimmunity.
Volume: 102
Pages: 65-76
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Publication
24508234 | J:209929
First Author: Behnsen J
Year: 2014
Journal: Immunity
Title: The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria.
Volume: 40
Issue: 2
Pages: 262-73
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Publication
27067635 | J:246947
First Author: Corneth OB
Year: 2016
Journal: Eur J Immunol
Title: Loss of IL-22 inhibits autoantibody formation in collagen-induced arthritis in mice.
Volume: 46
Issue: 6
Pages: 1404-14
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Publication
23585682 | J:202558
First Author: Zenewicz LA
Year: 2013
Journal: J Immunol
Title: IL-22 deficiency alters colonic microbiota to be transmissible and colitogenic.
Volume: 190
Issue: 10
Pages: 5306-12
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Publication
22952908 | J:191650
First Author: Wang P
Year: 2012
Journal: PLoS One
Title: IL-22 signaling contributes to West Nile encephalitis pathogenesis.
Volume: 7
Issue: 8
Pages: e44153
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Publication
36635952 | J:362230
First Author: Coronas V
Year: 2023
Journal: Stem Cells
Title: IL-22 Promotes Neural Stem Cell Self-Renewal in the Adult Brain.
Volume: 41
Issue: 3
Pages: 252-259
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Publication
33784296 | J:304386
First Author: P?rez-Cruz M
Year: 2021
Journal: PLoS One
Title: The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced infection in cigarette smoke-exposed mice.
Volume: 16
Issue: 3
Pages: e0236216
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Publication
24130494 | J:245985
First Author: Turner JE
Year: 2013
Journal: PLoS Pathog
Title: IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection.
Volume: 9
Issue: 10
Pages: e1003698
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Publication
23223145 | J:197959
First Author: McGee HM
Year: 2013
Journal: J Invest Dermatol
Title: IL-22 promotes fibroblast-mediated wound repair in the skin.
Volume: 133
Issue: 5
Pages: 1321-9
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Publication
21897855 | J:176141
First Author: Wang Z
Year: 2011
Journal: PLoS One
Title: High fat diet induces formation of spontaneous liposarcoma in mouse adipose tissue with overexpression of interleukin 22.
Volume: 6
Issue: 8
Pages: e23737
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Publication
26834739 | J:294335
 
First Author: Shen W
Year: 2015
Journal: Front Immunol
Title: IL-22-Expressing Murine Lymphocytes Display Plasticity and Pathogenicity in Reporter Mice.
Volume: 6
Pages: 662
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Publication
21465510 | J:294662
First Author: Park O
Year: 2011
Journal: Hepatology
Title: In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression.
Volume: 54
Issue: 1
Pages: 252-61
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Publication
17483407 | J:123019
First Author: Levillayer F
Year: 2007
Journal: Genetics
Title: Interleukin 22 is a candidate gene for Tmevp3, a locus controlling Theiler's virus-induced neurological diseases.
Volume: 176
Issue: 3
Pages: 1835-44
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Publication
18172556 | J:131041
First Author: Sugimoto K
Year: 2008
Journal: J Clin Invest
Title: IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis.
Volume: 118
Issue: 2
Pages: 534-44
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Publication
18202747 | J:131402
First Author: Ma HL
Year: 2008
Journal: J Clin Invest
Title: IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation.
Volume: 118
Issue: 2
Pages: 597-607
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Publication
17114505 | J:140678
First Author: Weber GF
Year: 2006
Journal: J Immunol
Title: IL-22-mediated tumor growth reduction correlates with inhibition of ERK1/2 and AKT phosphorylation and induction of cell cycle arrest in the G2-M phase.
Volume: 177
Issue: 11
Pages: 8266-72
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Publication
21795593 | J:179139
First Author: Ke Y
Year: 2011
Journal: J Immunol
Title: IL-22-induced regulatory CD11b+ APCs suppress experimental autoimmune uveitis.
Volume: 187
Issue: 5
Pages: 2130-9
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Publication
23375450 | J:194477
First Author: Scheiermann P
Year: 2013
Journal: Am J Pathol
Title: Application of interleukin-22 mediates protection in experimental acetaminophen-induced acute liver injury.
Volume: 182
Issue: 4
Pages: 1107-13
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Publication
24999596 | J:216202
First Author: Brosch S
Year: 2015
Journal: J Invest Dermatol
Title: Disease control in cutaneous leishmaniasis is independent of IL-22.
Volume: 135
Issue: 1
Pages: 308-311
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Publication
28356382 | J:247737
First Author: Martin JC
Year: 2017
Journal: J Immunol
Title: Limited Presence of IL-22 Binding Protein, a Natural IL-22 Inhibitor, Strengthens Psoriatic Skin Inflammation.
Volume: 198
Issue: 9
Pages: 3671-3678
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