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Search results 1 to 100 out of 876 for Insr

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
3643 | INSR
Type: gene
Organism: human
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Gene
100492718 | insr
Type: gene
Organism: frog, western clawed
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Gene
24954 | Insr
Type: gene
Organism: rat
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Gene
484990 | INSR
Type: gene
Organism: dog, domestic
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Gene
455649 | INSR
Type: gene
Organism: chimpanzee
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Gene
408017 | INSR
Type: gene
Organism: cattle
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Gene
420133 | INSR
Type: gene
Organism: chicken
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Gene
706009 | INSR
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:96575 | Insr
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15864351 | J:98087
First Author: Okamoto H
Year: 2005
Journal: J Clin Invest
Title: Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action.
Volume: 115
Issue: 5
Pages: 1314-22
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Publication
17299086 | J:121915
First Author: Kim JJ
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2.
Volume: 292
Issue: 6
Pages: E1694-701
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Publication
35136059 | J:354833
First Author: Skovs? S
Year: 2022
Journal: Nat Commun
Title: Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance.
Volume: 13
Issue: 1
Pages: 735
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Publication
40794792 | J:377974
First Author: Sekulovski N
Year: 2025
Journal: Biol Reprod
Title: Conditional ablation of Insr and Igf1r using Esr2-Cre leads to abnormal ovarian follicle development and infertility in mice?.
Volume: 113
Issue: 5
Pages: 1196-1208
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Publication
38790245 | J:353388
 
First Author: Douglas JC
Year: 2024
Journal: Genes (Basel)
Title: Normal Ovarian Function in Subfertile Mouse with Amhr2-Cre-Driven Ablation of Insr and Igf1r.
Volume: 15
Issue: 5
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Publication
26567220 | J:246896
First Author: Wei W
Year: 2016
Journal: J Cell Sci
Title: The NF-?B-modulated microRNAs miR-195 and miR-497 inhibit myoblast proliferation by targeting Igf1r, Insr and cyclin genes.
Volume: 129
Issue: 1
Pages: 39-50
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GXD Expression
GXD Expression
     
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190617
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Insr
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190617
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Insr
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190617
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Insr
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190617
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Insr
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190617
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Insr
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190617
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Insr
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6175520
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190617
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Insr
Detected: true
Specimen Num: 7
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Publication
- | J:267534
     
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for gummi_bear.
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Publication
- | J:267535
     
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Patently.
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Publication
12459269 | J:80773
First Author: Baudry A
Year: 2002
Journal: Gene
Title: Partial rescue of insulin receptor-deficient mice by transgenic complementation with an activated insulin receptor in the liver.
Volume: 299
Issue: 1-2
Pages: 219-25
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Publication
19933998 | J:164160
First Author: Lin HV
Year: 2010
Journal: Diabetes
Title: Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons.
Volume: 59
Issue: 2
Pages: 337-46
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Publication
21239487 | J:170633
First Author: Lin HV
Year: 2011
Journal: J Biol Chem
Title: Reconstitution of insulin action in muscle, white adipose tissue, and brain of insulin receptor knock-out mice fails to rescue diabetes.
Volume: 286
Issue: 11
Pages: 9797-804
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Publication
35523180 | J:326450
First Author: Chidambaram S
Year: 2022
Journal: Stem Cell Reports
Title: Subventricular zone adult mouse neural stem cells require insulin receptor for?self-renewal.
Volume: 17
Issue: 6
Pages: 1411-1427
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Publication
37913774 | J:342860
First Author: Podmore L
Year: 2023
Journal: Cell Rep
Title: Insulin receptor loss impairs mammary tumorigenesis in mice.
Volume: 42
Issue: 11
Pages: 113251
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Publication
39524330 | J:358426
First Author: Goedeke L
Year: 2024
Journal: iScience
Title: High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis.
Volume: 27
Issue: 11
Pages: 111175
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Publication
8612577 | J:32538
First Author: Joshi RL
Year: 1996
Journal: EMBO J
Title: Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality.
Volume: 15
Issue: 7
Pages: 1542-7
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Publication
34460911 | J:327000
 
First Author: Warmke N
Year: 2021
Journal: Endocrinology
Title: Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling.
Volume: 162
Issue: 11
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Publication
32816962 | J:300711
First Author: Brierley GV
Year: 2020
Journal: Diabetes
Title: Anti-Insulin Receptor Antibodies Improve Hyperglycemia in a Mouse Model of Human Insulin Receptoropathy.
Volume: 69
Issue: 11
Pages: 2481-2489
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Publication
34271222 | J:330003
 
First Author: Luo F
Year: 2021
Journal: Mol Metab
Title: Missense variant in insulin receptor (Y1355H) segregates in family with fatty liver disease.
Volume: 53
Pages: 101299
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Publication
3066742 | J:9626
First Author: Wang LM
Year: 1988
Journal: Genomics
Title: Chromosome assignment of mouse insulin, colony stimulating factor 1, and low-density lipoprotein receptors.
Volume: 3
Issue: 2
Pages: 172-6
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Publication
37175762 | J:338280
 
First Author: Sohail S
Year: 2023
Journal: Int J Mol Sci
Title: Sex Modulates Response to Renal-Tubule-Targeted Insulin Receptor Deletion in Mice.
Volume: 24
Issue: 9
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Publication
16127460 | J:100915
First Author: Banks AS
Year: 2005
Journal: J Clin Invest
Title: Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.
Volume: 115
Issue: 9
Pages: 2462-71
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Publication
26573296 | J:229018
First Author: Xia P
Year: 2015
Journal: J Exp Med
Title: Insulin-InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages.
Volume: 212
Issue: 13
Pages: 2305-21
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Publication
14722613 | J:87564
First Author: Kitamura T
Year: 2004
Journal: J Clin Invest
Title: Mosaic analysis of insulin receptor function.
Volume: 113
Issue: 2
Pages: 209-19
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Publication
31713233 | J:285779
First Author: Wu D
Year: 2020
Journal: Immunology
Title: Ectopic germline recombination activity of the widely used Foxp3-YFP-Cre mouse: a case report.
Volume: 159
Issue: 2
Pages: 231-241
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Publication
37399905 | J:367088
 
First Author: Gladding JM
Year: 2023
Journal: Appetite
Title: High fat diet allows food-predictive stimuli to energize action performance in the absence of hunger, without distorting insulin signaling on accumbal cholinergic interneurons.
Volume: 188
Pages: 106769
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Publication
23671263 | J:200951
First Author: Gahete MD
Year: 2013
Journal: Endocrinology
Title: Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.
Volume: 154
Issue: 7
Pages: 2410-20
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Publication
32478834 | J:294936
 
First Author: Wu D
Year: 2020
Journal: J Exp Med
Title: T reg-specific insulin receptor deletion prevents diet-induced and age-associated metabolic syndrome.
Volume: 217
Issue: 8
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Publication
35328354 | J:322862
 
First Author: Milanova IV
Year: 2022
Journal: Int J Mol Sci
Title: Loss of Microglial Insulin Receptor Leads to Sex-Dependent Metabolic Disorders in Obese Mice.
Volume: 23
Issue: 6
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Publication
37908089 | J:358169
 
First Author: Xue CY
Year: 2023
Journal: ASN Neuro
Title: Hippocampus Insulin Receptors Regulate Episodic and Spatial Memory Through Excitatory/Inhibitory Balance.
Volume: 15
Pages: 17590914231206657
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Publication
27760050 | J:239615
First Author: Petersen MC
Year: 2016
Journal: J Clin Invest
Title: Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance.
Volume: 126
Issue: 11
Pages: 4361-4371
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Publication
25685696 | J:223522
First Author: Chong AC
Year: 2015
Journal: Mol Metab
Title: Central insulin signaling modulates hypothalamus-pituitary-adrenal axis responsiveness.
Volume: 4
Issue: 2
Pages: 83-92
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Publication
22319636 | J:185235
First Author: Plum L
Year: 2012
Journal: PLoS One
Title: InsR/FoxO1 signaling curtails hypothalamic POMC neuron number.
Volume: 7
Issue: 2
Pages: e31487
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Publication
27150392 | J:246852
First Author: Liu J
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Type 1 Deiodinase Regulates ApoA-I Gene Expression and ApoA-I Synthesis Independent of Thyroid Hormone Signaling.
Volume: 36
Issue: 7
Pages: 1356-66
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Publication
29401624 | J:273822
First Author: Neirijnck Y
Year: 2018
Journal: FASEB J
Title: Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells.
Volume: 32
Issue: 6
Pages: 3321-3335
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Publication
32173454 | J:314325
 
First Author: Glendining KA
Year: 2020
Journal: Brain Behav Immun
Title: Maternal obesity modulates sexually dimorphic epigenetic regulation and expression of leptin receptor in offspring hippocampus.
Volume: 88
Pages: 151-160
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Publication
20032056 | J:158405
First Author: Liang L
Year: 2010
Journal: Endocrinology
Title: Insulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesis.
Volume: 151
Issue: 2
Pages: 741-7
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Publication
34037749 | J:343883
 
First Author: Walker AMN
Year: 2021
Journal: Endocrinology
Title: Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis.
Volume: 162
Issue: 8
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Publication
20947509 | J:167586
First Author: Xuan S
Year: 2010
Journal: J Biol Chem
Title: Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.
Volume: 285
Issue: 52
Pages: 41044-50
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Publication
23518924 | J:283285
First Author: Pitetti JL
Year: 2013
Journal: Mol Endocrinol
Title: An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.
Volume: 27
Issue: 5
Pages: 814-27
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Publication
30292429 | J:272636
 
First Author: Evans MC
Year: 2018
Journal: Horm Behav
Title: Leptin and insulin do not exert redundant control of metabolic or emotive function via dopamine neurons.
Volume: 106
Pages: 93-104
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Publication
25116708 | J:218718
First Author: Evans MC
Year: 2014
Journal: Endocrinology
Title: Insulin action on GABA neurons is a critical regulator of energy balance but not fertility in mice.
Volume: 155
Issue: 11
Pages: 4368-79
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Publication
33077977 | J:305004
First Author: Zhou B
Year: 2020
Journal: Nat Microbiol
Title: Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling.
Volume: 5
Issue: 12
Pages: 1576-1587
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Publication
28687614 | J:246859
First Author: Madhusudhan T
Year: 2017
Journal: Blood
Title: Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function.
Volume: 130
Issue: 12
Pages: 1445-1455
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Publication
30576429 | J:273133
First Author: Neirijnck Y
Year: 2019
Journal: Endocrinology
Title: Tumor Suppressor PTEN Regulates Negatively Sertoli Cell Proliferation, Testis Size, and Sperm Production In Vivo.
Volume: 160
Issue: 2
Pages: 387-398
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Publication
30909860 | J:273626
First Author: Wang K
Year: 2019
Journal: BMC Dev Biol
Title: Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development.
Volume: 19
Issue: 1
Pages: 5
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Publication
26888756 | J:250858
 
First Author: Groeneveld MP
Year: 2016
Journal: Sci Rep
Title: Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production.
Volume: 6
Pages: 21105
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Publication
15254588 | J:91350
First Author: Okamoto H
Year: 2004
Journal: J Clin Invest
Title: Transgenic rescue of insulin receptor-deficient mice.
Volume: 114
Issue: 2
Pages: 214-23
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Publication
30376348 | J:273890
First Author: Borges BC
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Insulin signaling in LepR cells modulates fat and glucose homeostasis independent of leptin.
Volume: 316
Issue: 1
Pages: E121-E134
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Publication
38816743 | J:349178
First Author: Moorwood K
Year: 2024
Journal: BMC Biol
Title: Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes.
Volume: 22
Issue: 1
Pages: 127
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Publication
12101187 | J:79280
First Author: Kido Y
Year: 2002
Journal: J Biol Chem
Title: Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance.
Volume: 277
Issue: 39
Pages: 36740-7
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Publication
31318893 | J:277295
First Author: Jin J
Year: 2019
Journal: PLoS One
Title: Igf1R/InsR function is required for axon extension and corpus callosum formation.
Volume: 14
Issue: 7
Pages: e0219362
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Publication
21429986 | J:171220
First Author: Li P
Year: 2011
Journal: Development
Title: IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development.
Volume: 138
Issue: 9
Pages: 1795-805
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Publication
33505018 | J:305792
First Author: Ansarullah
Year: 2021
Journal: Nature
Title: Inceptor counteracts insulin signalling in ?-cells to control glycaemia.
Volume: 590
Issue: 7845
Pages: 326-331
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Publication
11463843 | J:70602
First Author: Kitamura T
Year: 2001
Journal: Mol Cell Biol
Title: Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor.
Volume: 21
Issue: 16
Pages: 5624-30
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Publication
21641549 | J:176088
First Author: Deyev IE
Year: 2011
Journal: Cell Metab
Title: Insulin receptor-related receptor as an extracellular alkali sensor.
Volume: 13
Issue: 6
Pages: 679-89
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Publication
21681845 | J:175639
First Author: Erickson RP
Year: 2011
Journal: Mol Reprod Dev
Title: Insulin receptor-related (Irr) is expressed in pre-implantation embryos: a possible relationship to "growth factor Y" and sex determination.
Volume: 78
Issue: 8
Pages: 552
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Protein Coding Gene
MGP_CAROLIEiJ_G0030765 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0033299 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033213 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032996 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033792 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032969 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033123 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033215 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032432 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021238 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031873 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2557333 | J:32474
First Author: Flores-Riveros JR
Year: 1989
Journal: J Biol Chem
Title: Substrate phosphorylation catalyzed by the insulin receptor tyrosine kinase. Kinetic correlation to autophosphorylation of specific sites in the beta subunit.
Volume: 264
Issue: 36
Pages: 21557-72
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Publication
2602374 | J:10185
First Author: Sibley E
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Characterization of the mouse insulin receptor gene promoter.
Volume: 86
Issue: 24
Pages: 9732-6
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Publication
9398630 | J:44320
First Author: McKeon C
Year: 1997
Journal: Biochem Biophys Res Commun
Title: A conserved region in the first intron of the insulin receptor gene binds nuclear proteins during adipocyte differentiation.
Volume: 240
Issue: 3
Pages: 701-6
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Publication
8083370 | J:20454
First Author: Huang Z
Year: 1994
Journal: J Clin Invest
Title: Hyperinsulinemia is associated with altered insulin receptor mRNA splicing in muscle of the spontaneously obese diabetic rhesus monkey.
Volume: 94
Issue: 3
Pages: 1289-96
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Publication
8528241 | J:33408
First Author: Accili D
Year: 1996
Journal: Nat Genet
Title: Early neonatal death in mice homozygous for a null allele of the insulin receptor gene.
Volume: 12
Issue: 1
Pages: 106-9
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Publication
11181540 | J:68780
First Author: Wertheimer E
Year: 2001
Journal: Endocrinology
Title: The regulation of skin proliferation and differentiation in the IR null mouse: implications for skin complications of diabetes.
Volume: 142
Issue: 3
Pages: 1234-41
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Publication
31671785 | J:293608
 
First Author: Meroni M
Year: 2019
Journal: Nutrients
Title: mir-101-3p Downregulation Promotes Fibrogenesis by Facilitating Hepatic Stellate Cell Transdifferentiation During Insulin Resistance.
Volume: 11
Issue: 11
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Publication
16176826 | J:106630
First Author: Das P
Year: 2005
Journal: Physiol Behav
Title: Electrophysiological and behavioral phenotype of insulin receptor defective mice.
Volume: 86
Issue: 3
Pages: 287-96
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Publication
9498650 | J:107160
First Author: Cinti S
Year: 1998
Journal: Diabetologia
Title: Lack of insulin receptors affects the formation of white adipose tissue in mice. A morphometric and ultrastructural analysis.
Volume: 41
Issue: 2
Pages: 171-7
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