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Search results 1 to 100 out of 2071 for Jag1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
182 | JAG1
Type: gene
Organism: human
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Gene
100486874 | jag1
Type: gene
Organism: frog, western clawed
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Gene
29146 | Jag1
Type: gene
Organism: rat
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Gene
748073 | JAG1
Type: gene
Organism: chimpanzee
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Gene
485769 | JAG1
Type: gene
Organism: dog, domestic
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Gene
783681 | JAG1
Type: gene
Organism: cattle
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Gene
396043 | JAG1
Type: gene
Organism: chicken
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Gene
718580 | JAG1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR033108 | Jag1
Type: Family
Description: Ligand binding triggers the proteolytic cleavage of NOTCH receptors, whichis mediated by distinct enzymes []. Jagged-1 (JAG2) is a ligand for the Notch receptors []. The Jagged-Notch signalling plays important roles in the maintenance of proliferating neural precursors [, ]and in kidney development [].
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Protein Coding Gene
MGI:1095416 | Jag1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6403323
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6403335
Age: embryonic day 10.5-10.75
Image: 2C JAG1
Note: Localized expression in posterior-distal mesenchyme.
Specimen Label: 2C JAG1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7520379
Assay Type: RNA in situ
Annotation Date: 2023-08-25
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1702321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7520454
Age: embryonic day 13.5
Image: 6B Jag1
Note: Very low levels of expression in epithelial cells.
Specimen Label: 6B Jag1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6403323
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6403335
Age: embryonic day 10.5-10.75
Image: 6C JAG1
Note: Only a small fraction cells co-express tdTOMATO.
Specimen Label: 6C JAG1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7520379
Assay Type: RNA in situ
Annotation Date: 2023-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7520454
Age: embryonic day 13.5
Image: 6B Jag1
Specimen Label: 6B Jag1
Detected: true
Specimen Num: 1
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Publication
10958687 | J:88030
First Author: Shimizu K
Year: 2000
Journal: Mol Cell Biol
Title: Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.
Volume: 20
Issue: 18
Pages: 6913-22
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GXD Expression
GXD Expression
Probe: MGI:6856705
Assay Type: Immunohistochemistry
Annotation Date: 2022-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6856710
Age: embryonic day 12.0
Image: S2C JAG1 E12
Note: Expression in region of ventricular/subventricular zone, co-localized with GLAST (Slc1a3).
Specimen Label: S2C JAG1 E12
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6856705
Assay Type: Immunohistochemistry
Annotation Date: 2022-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6856710
Age: embryonic day 14.0
Image: S2C JAG1 E14
Note: Expression in region of ventricular/subventricular zone, co-localized with GLAST (Slc1a3).
Specimen Label: S2C JAG1 E14
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6403309
Assay Type: RNA in situ
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6403327
Age: embryonic day 10.5-10.75
Image: 2A Jag1 (left)
Note: Localized expression in posterior-distal mesenchyme.
Specimen Label: 2A Jag1 (left)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6403309
Assay Type: RNA in situ
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6403327
Age: embryonic day 10.5-10.75
Image: 2A Jag1 (right)
Note: Localized expression in posterior-distal mesenchyme.
Specimen Label: 2A Jag1 (right)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6403323
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6403335
Age: embryonic day 10.5-10.75
Image: S2 JAG1 E10.5-E10.75
Note: Localized expression in posterior-distal mesenchyme.
Specimen Label: S2 JAG1 E10.5-E10.75
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6403323
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:6403335
Age: embryonic day 11.5
Image: S2 JAG1 E11.5
Note: Expression overlaps with Sox9 in anterior mesenchyme.
Specimen Label: S2 JAG1 E11.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6107771
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1620415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7276246
Age: embryonic day 9.5
Image: 2F +/+ Jag1
Specimen Label: 2F +/+ Jag1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6107771
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1620415
Stage: TS15
Assay Id: MGI:7276246
Age: embryonic day 9.5
Image: 2F -/- Jag1
Note: Authors report lack of expression in mutant embryos.
Specimen Label: 2F -/- Jag1
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6856705
Assay Type: Immunohistochemistry
Annotation Date: 2022-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6856710
Age: embryonic day 12.0
Image: S2C JAG1 E12
Note: Expression in region of ventricular/subventricular zone, co-localized with GLAST (Slc1a3).
Specimen Label: S2C JAG1 E12
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6856705
Assay Type: Immunohistochemistry
Annotation Date: 2022-01-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6856710
Age: embryonic day 14.0
Image: S2C JAG1 E14
Note: Expression in region of ventricular/subventricular zone, co-localized with GLAST (Slc1a3).
Specimen Label: S2C JAG1 E14
Detected: true
Specimen Num: 2
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Publication
24708907 | -
 
First Author: Fiaschetti G
Year: 2014
Journal: Acta Neuropathol Commun
Title: NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma.
Volume: 2
Pages: 39
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GXD Expression
GXD Expression
Probe: MGI:5811416
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640617
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5823649
Age: embryonic day 10.5
Image: S1A - Jag1 - E10.5
Note: This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud.
Specimen Label: S1A - Jag1 - E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5811416
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5823649
Age: embryonic day 11.5
Image: S1A - Jag1 - E11.5
Note: This gene exhibits category 1 expression: staining is observed in the posterior/posterior-distal limb bud.
Specimen Label: S1A - Jag1 - E11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7346136
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7531486
Age: embryonic day 12.5
Image: 1B E12.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Jag1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7346136
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531486
Age: embryonic day 14.5
Image: 1B E14.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Jag1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7427589
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7531510
Age: embryonic day 12.5
Image: 1B E12.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Jag1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7427589
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531510
Age: embryonic day 14.5
Image: 1B E14.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Jag1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6236285
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7531511
Age: embryonic day 12.5
Image: 1B E12.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Jag1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6236285
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531511
Age: embryonic day 14.5
Image: 1B E14.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Jag1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7346136
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7531486
Age: embryonic day 18.5
Image: 1B E18.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E18.5 with Jag1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7427589
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7531510
Age: embryonic day 18.5
Image: 1B E18.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E18.5 with Jag1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6236285
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7531511
Age: embryonic day 18.5
Image: 1B E18.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E18.5 with Jag1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7346136
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2808922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531486
Age: embryonic day 14.5
Image: 1B E14.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Jag1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7346136
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2808926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7531486
Age: embryonic day 18.5
Image: 1B E18.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E18.5 with Jag1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7427589
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2808922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531510
Age: embryonic day 14.5
Image: 1B E14.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Jag1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7427589
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2808926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7531510
Age: embryonic day 18.5
Image: 1B E18.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E18.5 with Jag1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6236285
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2808922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531511
Age: embryonic day 14.5
Image: 1B E14.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Jag1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6236285
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2808926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7531511
Age: embryonic day 18.5
Image: 1B E18.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E18.5 with Jag1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7346136
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2770820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7531486
Age: embryonic day 12.5
Image: 1B E12.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Jag1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7427589
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2770820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7531510
Age: embryonic day 12.5
Image: 1B E12.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Jag1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6236285
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2770820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7531511
Age: embryonic day 12.5
Image: 1B E12.5 with Jag1
Note: Proximity signals were observed for JAG1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Jag1
Detected: true
Specimen Num: 1
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Protein
Q9QXX0
Organism: Mus musculus/domesticus
Length: 1218  
Fragment?: false
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Protein
Q3UVN4
Organism: Mus musculus/domesticus
Length: 1218  
Fragment?: false
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Protein
Q3TS72
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: true
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Protein
Q8C5M7
Organism: Mus musculus/domesticus
Length: 227  
Fragment?: true
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Protein
A0A1Y7VLS8
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: true
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Publication
20680491 | -
First Author: Gwak JW
Year: 2010
Journal: Mol Cells
Title: Proliferating neural progenitors in the developing CNS of zebrafish require Jagged2 and Jagged1b.
Volume: 30
Issue: 2
Pages: 155-9
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Publication
17389390 | -
First Author: Yeo SY
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Jagged-mediated Notch signaling maintains proliferating neural progenitors and regulates cell diversity in the ventral spinal cord.
Volume: 104
Issue: 14
Pages: 5913-8
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Publication
17257056 | -
First Author: Ma M
Year: 2007
Journal: PLoS Genet
Title: Jagged2a-notch signaling mediates cell fate choice in the zebrafish pronephric duct.
Volume: 3
Issue: 1
Pages: e18
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Publication
28051360 | J:326005
First Author: Garcia TX
Year: 2017
Journal: Stem Cells Dev
Title: The NOTCH Ligand JAG1 Regulates GDNF Expression in Sertoli Cells.
Volume: 26
Issue: 8
Pages: 585-598
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Publication
17890364 | J:125211
First Author: Kiernan AE
Year: 2007
Journal: Genetics
Title: Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice.
Volume: 177
Issue: 1
Pages: 307-11
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Publication
16410827 | J:115783
First Author: Kiernan AE
Year: 2006
Journal: PLoS Genet
Title: The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear.
Volume: 2
Issue: 1
Pages: e4
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Publication
16875832 | J:114447
First Author: Vrijens K
Year: 2006
Journal: Neurobiol Dis
Title: Ozzy, a Jag1 vestibular mouse mutant, displays characteristics of Alagille syndrome.
Volume: 24
Issue: 1
Pages: 28-40
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Publication
31609444 | J:283686
First Author: Hubbard N
Year: 2019
Journal: Endocrinology
Title: Activation of Notch Signaling by Oocytes and Jag1 in Mouse Ovarian Granulosa Cells.
Volume: 160
Issue: 12
Pages: 2863-2876
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Publication
21068062 | J:166769
First Author: Feng X
Year: 2010
Journal: Development
Title: Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.
Volume: 137
Issue: 24
Pages: 4191-9
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Publication
17366661 | J:149131
First Author: Loomes KM
Year: 2007
Journal: Hepatology
Title: Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.
Volume: 45
Issue: 2
Pages: 323-30
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Publication
24391948 | J:211111
First Author: Underkoffler LA
Year: 2013
Journal: PLoS One
Title: Microarray data reveal relationship between Jag1 and Ddr1 in mouse liver.
Volume: 8
Issue: 12
Pages: e84383
•
•
•
•
•
Publication
31273345 | J:327537
First Author: Zhang L
Year: 2020
Journal: Genet Med
Title: Exome sequencing revealed Notch ligand JAG1 as a novel candidate gene for familial exudative vitreoretinopathy.
Volume: 22
Issue: 1
Pages: 77-84
•
•
•
•
•
Publication
11861489 | J:74574
First Author: McCright B
Year: 2002
Journal: Development
Title: A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency.
Volume: 129
Issue: 4
Pages: 1075-82
•
•
•
•
•
Publication
19208348 | J:148722
First Author: Golson ML
Year: 2009
Journal: Gastroenterology
Title: Ductal malformation and pancreatitis in mice caused by conditional Jag1 deletion.
Volume: 136
Issue: 5
Pages: 1761-71.e1
•
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•
•
•
Publication
32059775 | J:297252
First Author: Seymour PA
Year: 2020
Journal: Dev Cell
Title: Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors.
Volume: 52
Issue: 6
Pages: 731-747.e8
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•
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•
Publication
28045060 | J:274500
 
First Author: Kumar P
Year: 2017
Journal: Sci Rep
Title: Soluble OX40L and JAG1 Induce Selective Proliferation of Functional Regulatory T-Cells Independent of canonical TCR signaling.
Volume: 7
Pages: 39751
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•
•
•
•
Publication
23095891 | J:189213
First Author: Hofmann JJ
Year: 2012
Journal: Development
Title: Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome.
Volume: 139
Issue: 23
Pages: 4449-60
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•
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•
Publication
39358604 | J:358367
First Author: Mašek J
Year: 2024
Journal: EMBO Mol Med
Title: Jag1 insufficiency alters liver fibrosis via T cell and hepatocyte differentiation defects.
Volume: 16
Issue: 11
Pages: 2946-2975
•
•
•
•
•
Publication
39373109 | J:359963
 
First Author: de Haan S
Year: 2024
Journal: Development
Title: Jag1 represses Notch activation in lateral supporting cells and inhibits an outer hair cell fate in the medial cochlea.
Volume: 151
Issue: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4428862
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4825671
Age: embryonic day 14.5
Note: Expression is present in single cells in which the intercellular distance between stained cells is much larger than the cell diameter of an individual cell. A thumbnail photo of the staining is contained in the table.
Specimen Label: Table S9 - Jag1
Detected: true
Specimen Num: 1
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•
•
•
•
Publication
25535917 | J:310741
First Author: Briot A
Year: 2014
Journal: Dev Cell
Title: Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.
Volume: 31
Issue: 6
Pages: 707-21
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•
•
•
•
Publication
- | J:97122
     
First Author: Shahim H
Year: 2005
Journal: MGI Direct Data Submission
Title: Headchuck, an ENU-generated mutation of Jag1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7346136
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1795024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7531486
Age: embryonic day 16.5
Image: 1B E16.5 with Jag1
Note: At E16.5, proximity signals were not observed.
Specimen Label: 1B E16.5 with Jag1
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7427589
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1795024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7531510
Age: embryonic day 16.5
Image: 1B E16.5 with Jag1
Note: At E16.5, proximity signals were not observed.
Specimen Label: 1B E16.5 with Jag1
Specimen Num: 3
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6236285
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1795024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7531511
Age: embryonic day 16.5
Image: 1B E16.5 with Jag1
Note: At E16.5, proximity signals were not observed.
Specimen Label: 1B E16.5 with Jag1
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5308083
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6695145
Age: embryonic day 18.5
Image: 2B Jag1 cnull
Note: Increased expression (2.5 fold) compared with the control.
Specimen Label: 2B Jag1 cnull
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6155601
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6695142
Age: embryonic day 18.5
Image: 2B Jag1 cnull
Note: Reduced expression compared with the control and Jag2cnull.
Specimen Label: 2B Jag1 cnull
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5497024
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269526
Pattern: Clusters
Stage: TS26
Assay Id: MGI:6695177
Age: embryonic day 18.5
Image: 3B Jag1 cnull
Note: Expressed in neuroepithelial bodies, similar as in the control.
Specimen Label: 3B Jag1 cnull
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6694992
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6695148
Age: embryonic day 18.5
Image: 3B Jag1 cnull
Note: Expressed in secretory precursors, similar as in the control.
Specimen Label: 3B Jag1 cnull
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6694990
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6695149
Age: embryonic day 18.5
Image: 3B Jag1 cnull
Note: Expressed in secretory precursors, similar as in the control.
Specimen Label: 3B Jag1 cnull
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6393551
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6695205
Age: embryonic day 18.5
Image: 2-S1B Jag1 cnull
Note: Expressed in basal cell progenitors, similar in the control.
Specimen Label: 2-S1B Jag1 cnull
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5308083
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6695204
Age: embryonic day 18.5
Image: 2-S1B Jag1 cnull
Note: A trend (not significant) towards an increase in the abundance of the multiciliated cell population compared with the control.
Specimen Label: 2-S1B Jag1 cnull
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6175709
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190647
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Jag1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6175709
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190647
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Jag1
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6175709
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190647
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Jag1
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6175709
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190647
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Jag1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6175709
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190647
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Jag1
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6175709
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190647
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Jag1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6175709
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190647
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Jag1
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6763032
Age: embryonic day 12.5
Image: 10D
Note: Jag1 and Sox2 exhibited largely overlapping expression domains.
Specimen Label: 10D
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
33268505 | J:305012
 
First Author: Chung WC
Year: 2021
Journal: Life Sci Alliance
Title: Loss of Jag1 cooperates with oncogenic Kras to induce pancreatic cystic neoplasms.
Volume: 4
Issue: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7531485
Age: embryonic day 12.5
Image: 1B E12.5 with Notch1
Note: Proximity signals were observed for JAG1 with NOTCH1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Notch1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7531485
Age: embryonic day 12.5
Image: 1B E12.5 with Notch2
Note: Proximity signals were observed for JAG1 with NOTCH2 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Notch2
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7531485
Age: embryonic day 12.5
Image: 1B E12.5 with Notch3
Note: Proximity signals were observed for JAG1 with NOTCH3 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E12.5 with Notch3
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531485
Age: embryonic day 14.5
Image: 1B E14.5 with Notch1
Note: Proximity signals were observed for JAG1 with NOTCH1 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Notch1
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531485
Age: embryonic day 14.5
Image: 1B E14.5 with Notch2
Note: Proximity signals were observed for JAG1 with NOTCH2 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Notch2
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7531485
Age: embryonic day 14.5
Image: 1B E14.5 with Notch3
Note: Proximity signals were observed for JAG1 with NOTCH3 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E14.5 with Notch3
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7531485
Age: embryonic day 18.5
Image: 1B E18.5 with Notch2
Note: Proximity signals were observed for JAG1 with NOTCH2 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E18.5 with Notch2
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5646173
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2771126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7531485
Age: embryonic day 18.5
Image: 1B E18.5 with Notch3
Note: Proximity signals were observed for JAG1 with NOTCH3 in the ureteric mesenchyme and ureteric epithelium.
Specimen Label: 1B E18.5 with Notch3
Detected: true
Specimen Num: 14
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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