| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mains RE |
| Year: |
2011 |
| Journal: |
BMC Neurosci |
| Title: |
Kalrn promoter usage and isoform expression respond to chronic cocaine exposure. |
| Volume: |
12 |
|
| Pages: |
20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mandela P |
| Year: |
2014 |
| Journal: |
Horm Behav |
| Title: |
Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning. |
| Volume: |
66 |
| Issue: |
2 |
| Pages: |
430-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mandela P |
| Year: |
2012 |
| Journal: |
BMC Neurosci |
| Title: |
Kalrn plays key roles within and outside of the nervous system. |
| Volume: |
13 |
|
| Pages: |
136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kiraly DD |
| Year: |
2013 |
| Journal: |
Mol Pharmacol |
| Title: |
Constitutive knockout of kalirin-7 leads to increased rates of cocaine self-administration. |
| Volume: |
84 |
| Issue: |
4 |
| Pages: |
582-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vanleeuwen JE |
| Year: |
2012 |
| Journal: |
J Neurochem |
| Title: |
Long-term perturbation of spine plasticity results in distinct impairments of cognitive function. |
| Volume: |
123 |
| Issue: |
5 |
| Pages: |
781-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie Z |
| Year: |
2011 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Hippocampal phenotypes in kalirin-deficient mice. |
| Volume: |
46 |
| Issue: |
1 |
| Pages: |
45-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma XM |
| Year: |
2014 |
| Journal: |
Mol Biol Cell |
| Title: |
Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl. |
| Volume: |
25 |
| Issue: |
9 |
| Pages: |
1458-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yan Y |
| Year: |
2015 |
| Journal: |
Cereb Cortex |
| Title: |
Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching. |
| Volume: |
25 |
| Issue: |
10 |
| Pages: |
3487-501 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Miller MB |
| Year: |
2017 |
| Journal: |
J Neurochem |
| Title: |
Alternate promoter usage generates two subpopulations of the neuronal RhoGEF Kalirin-7. |
| Volume: |
140 |
| Issue: |
6 |
| Pages: |
889-902 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu JH |
| Year: |
2013 |
| Journal: |
Arterioscler Thromb Vasc Biol |
| Title: |
Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells. |
| Volume: |
33 |
| Issue: |
4 |
| Pages: |
702-8 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cahill ME |
| Year: |
2009 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes. |
| Volume: |
106 |
| Issue: |
31 |
| Pages: |
13058-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Krivinko JM |
| Year: |
2017 |
| Journal: |
Neurobiol Aging |
| Title: |
Kalirin reduction rescues psychosis-associated behavioral deficits in APPswe/PSEN1dE9 transgenic mice. |
| Volume: |
54 |
|
| Pages: |
59-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lemtiri-Chlieh F |
| Year: |
2011 |
| Journal: |
BMC Neurosci |
| Title: |
Kalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticity. |
| Volume: |
12 |
|
| Pages: |
126 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kiraly DD |
| Year: |
2010 |
| Journal: |
Biol Psychiatry |
| Title: |
Behavioral and morphological responses to cocaine require kalirin7. |
| Volume: |
68 |
| Issue: |
3 |
| Pages: |
249-55 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie Z |
| Year: |
2010 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Kalirin loss results in cortical morphological alterations. |
| Volume: |
43 |
| Issue: |
1 |
| Pages: |
81-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang X |
| Year: |
2013 |
| Journal: |
J Neurosci |
| Title: |
Kalirin-7 mediates cocaine-induced AMPA receptor and spine plasticity, enabling incentive sensitization. |
| Volume: |
33 |
| Issue: |
27 |
| Pages: |
11012-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Moyer CE |
| Year: |
2016 |
| Journal: |
Cereb Cortex |
| Title: |
Developmental Trajectories of Auditory Cortex Synaptic Structures and Gap-Prepulse Inhibition of Acoustic Startle Between Early Adolescence and Young Adulthood in Mice. |
| Volume: |
26 |
| Issue: |
5 |
| Pages: |
2115-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grubisha MJ |
| Year: |
2021 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A Kalirin missense mutation enhances dendritic RhoA signaling and leads to regression of cortical dendritic arbors across development. |
| Volume: |
118 |
| Issue: |
49 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cahill ME |
| Year: |
2013 |
| Journal: |
J Neurochem |
| Title: |
Neuregulin1 signaling promotes dendritic spine growth through kalirin. |
| Volume: |
126 |
| Issue: |
5 |
| Pages: |
625-35 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4426819 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-04-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271122 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7621108 |
| Age: |
embryonic day 14.5 |
|
| Note: |
Cortical plate expression was greater than in the ventricular zone. |
| Specimen Label: |
Supplementary table 2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6457457 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-12-22 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1666823 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:6488099 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
S1 Table B42 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4426819 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2024-04-16 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754722 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7621108 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
Supplementary table 2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6457457 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2020-12-22 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757723 |
| Pattern: |
Ubiquitous |
| Stage: |
TS23 |
| Assay Id: |
MGI:6488099 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
S1 Table B42 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ma XM |
| Year: |
2008 |
| Journal: |
J Neurosci |
| Title: |
Kalirin-7 is required for synaptic structure and function. |
| Volume: |
28 |
| Issue: |
47 |
| Pages: |
12368-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang S |
| Year: |
2014 |
| Journal: |
Bone |
| Title: |
The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts. |
| Volume: |
60 |
|
| Pages: |
235-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McClory H |
| Year: |
2018 |
| Journal: |
Sci Rep |
| Title: |
The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival. |
| Volume: |
8 |
| Issue: |
1 |
| Pages: |
8000 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
LaRese TP |
| Year: |
2017 |
| Journal: |
BMC Neurosci |
| Title: |
Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviors. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu J |
| Year: |
2015 |
| Journal: |
Nat Commun |
| Title: |
A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses. |
| Volume: |
6 |
|
| Pages: |
6820 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paskus JD |
| Year: |
2019 |
| Journal: |
Cell Rep |
| Title: |
Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action. |
| Volume: |
29 |
| Issue: |
10 |
| Pages: |
2944-2952.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Herring BE |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP. |
| Volume: |
113 |
| Issue: |
8 |
| Pages: |
2264-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Russo-Savage L |
| Year: |
2020 |
| Journal: |
Neurobiol Aging |
| Title: |
Role of Kalirin and mouse strain in retention of spatial memory training in an Alzheimer's disease model mouse line. |
| Volume: |
95 |
|
| Pages: |
69-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Afroz S |
| Year: |
2016 |
| Journal: |
Elife |
| Title: |
Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines. |
| Volume: |
5 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kiraly DD |
| Year: |
2011 |
| Journal: |
J Neurosci |
| Title: |
Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function. |
| Volume: |
31 |
| Issue: |
35 |
| Pages: |
12554-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chakrabarti K |
| Year: |
2005 |
| Journal: |
Mol Cell Biol |
| Title: |
Critical role for Kalirin in nerve growth factor signaling through TrkA. |
| Volume: |
25 |
| Issue: |
12 |
| Pages: |
5106-18 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cissé M |
| Year: |
2017 |
| Journal: |
Mol Psychiatry |
| Title: |
The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model. |
| Volume: |
22 |
| Issue: |
11 |
| Pages: |
1562-1575 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brand F |
| Year: |
2012 |
| Journal: |
Mol Cell Biol |
| Title: |
The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology. |
| Volume: |
32 |
| Issue: |
13 |
| Pages: |
2467-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Owczarek S |
| Year: |
2015 |
| Journal: |
Neural Plast |
| Title: |
Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 "Signalosome". |
| Volume: |
2015 |
|
| Pages: |
167308 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hayashi-Takagi A |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence. |
| Volume: |
111 |
| Issue: |
17 |
| Pages: |
6461-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niu F |
| Year: |
2022 |
| Journal: |
Elife |
| Title: |
The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells. |
| Volume: |
11 |
|
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
58
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gu Z |
| Year: |
2015 |
| Journal: |
PLoS One |
| Title: |
Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. |
| Volume: |
10 |
| Issue: |
3 |
| Pages: |
e0121550 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
NIH Mouse Knockout Inventory |
| Year: |
2004 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GO Central curators, GOA curators, Rhea curators |
| Year: |
2020 |
|
| Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators, MGI curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Mouse Synonym Curation |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
| Journal: |
Database Download |
| Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2016 |
|
| Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bedogni F |
| Year: |
2021 |
| Journal: |
Front Mol Neurosci |
| Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
| Volume: |
14 |
|
| Pages: |
686034 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
|
| Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
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