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Search results 1 to 90 out of 90 for Kcnq5

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
56479 | KCNQ5
Type: gene
Organism: human
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Gene
613605 | KCNQ5
Type: gene
Organism: cattle
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Gene
421866 | KCNQ5
Type: gene
Organism: chicken
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Gene
715426 | KCNQ5
Type: gene
Organism: macaque, rhesus
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Gene
100488199 | kcnq5
Type: gene
Organism: frog, western clawed
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Gene
474965 | KCNQ5
Type: gene
Organism: dog, domestic
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Gene
462817 | KCNQ5
Type: gene
Organism: chimpanzee
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Gene
259273 | Kcnq5
Type: gene
Organism: rat
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Protein Domain
IPR043238 | KCNQ5
Type: Family
Description: KCNQ proteins have six transmembrane domains and are structurally related to Kv potassium channels. KCNQ5 is a member of the KCNQ potassium channel family. It is widely expressed in the brain and generates M-type current []. It may also contribute to the afterhyperpolarization currents in hippocampus in a cell type-specific manner []. Interestingly, KCNQ channels can form homomers as well as heteromers with each other (i.e., KCNQ2/KCNQ3, KCNQ3/KCNQ5, KCNQ3/KCNQ4), thus creating multiple possible combinations of KCNQ-mediated currents []. Mutations in the KCNQ5 gene cause intellectual disability or epileptic encephalopathy [].
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Protein Coding Gene
MGI:1924937 | Kcnq5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20534576 | J:195336
First Author: Tzingounis AV
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus.
Volume: 107
Issue: 22
Pages: 10232-7
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Gene
112267960 | KCNQ5-DT
Type: gene
Organism: human
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Gene
100507381 | KCNQ5-IT1
Type: gene
Organism: human
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Gene
100873997 | KCNQ5-AS1
Type: gene
Organism: human
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Publication
18457656 | J:136235
First Author: Yeung SY
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Expression profile and characterisation of a truncated KCNQ5 splice variant.
Volume: 371
Issue: 4
Pages: 741-6
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Publication
35583973 | J:349348
First Author: Wei AD
Year: 2022
Journal: J Neurophysiol
Title: Human KCNQ5 de novo mutations underlie epilepsy and intellectual disability.
Volume: 128
Issue: 1
Pages: 40-61
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Publication
28669405 | -
First Author: Lehman A
Year: 2017
Journal: Am J Hum Genet
Title: Loss-of-Function and Gain-of-Function Mutations in KCNQ5 Cause Intellectual Disability or Epileptic Encephalopathy.
Volume: 101
Issue: 1
Pages: 65-74
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Publication
25649132 | J:221364
 
First Author: Fidzinski P
Year: 2015
Journal: Nat Commun
Title: KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.
Volume: 6
Pages: 6254
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Publication
23408425 | J:197837
First Author: Spitzmaul G
Year: 2013
Journal: J Biol Chem
Title: Vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models.
Volume: 288
Issue: 13
Pages: 9334-44
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Publication
15963599 | J:101565
First Author: Jensen HS
Year: 2005
Journal: Brain Res Mol Brain Res
Title: The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.
Volume: 139
Issue: 1
Pages: 52-62
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Publication
11252765 | -
First Author: Jentsch TJ
Year: 2000
Journal: Nat Rev Neurosci
Title: Neuronal KCNQ potassium channels: physiology and role in disease.
Volume: 1
Issue: 1
Pages: 21-30
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Protein
G3UZ84
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
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Protein
Q9JK45
Organism: Mus musculus/domesticus
Length: 933  
Fragment?: false
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Protein
E9Q9F1
Organism: Mus musculus/domesticus
Length: 952  
Fragment?: false
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Protein
G3UYG5
Organism: Mus musculus/domesticus
Length: 924  
Fragment?: false
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Protein
G3UYP4
Organism: Mus musculus/domesticus
Length: 823  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0013991 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0015881 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0015862 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0015819 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0015818 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0015652 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1924937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016272 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015231 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0015624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0015723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0015727 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0015795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0015747 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015294 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027240 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0014795 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3707769
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:3708945
Age: embryonic day 17.5
Specimen Label: Fetus
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3707769
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:3708945
Age: postnatal day 1
Specimen Label: Neonate
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3707769
Assay Type: RT-PCR
Annotation Date: 2007-05-16
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3708945
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 3
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Publication
24838176 | J:247236
First Author: Schleifenbaum J
Year: 2014
Journal: Circ Res
Title: Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.
Volume: 115
Issue: 2
Pages: 263-72
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Publication
31024170 | J:331853
First Author: Gao R
Year: 2019
Journal: Cell Res
Title: Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.
Volume: 29
Issue: 6
Pages: 486-501
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Publication
16985003 | J:119550
First Author: Harrell MD
Year: 2007
Journal: Physiol Genomics
Title: Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.
Volume: 28
Issue: 3
Pages: 273-83
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Publication
27480124 | J:237787
First Author: Liu X
Year: 2016
Journal: BMC Immunol
Title: Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Volume: 17
Issue: 1
Pages: 25
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0080237 | autosomal dominant intellectual developmental disorder 46
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Publication
39153478 | J:353811
     
First Author: Tian G
Year: 2024
Journal: Neuron
Title: Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity.
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Publication
29748663 | J:262937
First Author: Manville RW
Year: 2018
Journal: Nat Commun
Title: Direct neurotransmitter activation of voltage-gated potassium channels.
Volume: 9
Issue: 1
Pages: 1847
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Publication
24719109 | J:208109
First Author: Soh H
Year: 2014
Journal: J Neurosci
Title: Conditional deletions of epilepsy-associated KCNQ2 and KCNQ3 channels from cerebral cortex cause differential effects on neuronal excitability.
Volume: 34
Issue: 15
Pages: 5311-21
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Publication
21849543 | J:254146
First Author: Roepke TA
Year: 2011
Journal: J Neurosci
Title: Fasting and 17β-estradiol differentially modulate the M-current in neuropeptide Y neurons.
Volume: 31
Issue: 33
Pages: 11825-35
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Publication
23977150 | J:205838
First Author: Robbins J
Year: 2013
Journal: PLoS One
Title: Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents.
Volume: 8
Issue: 8
Pages: e71809
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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