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Search results 1 to 100 out of 159 for Klrg1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
10219 | KLRG1
Type: gene
Organism: human
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Gene
134806924 | KLRG1
Type: gene
Organism: chimpanzee
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Gene
58975 | Klrg1
Type: gene
Organism: rat
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Gene
611464 | KLRG1
Type: gene
Organism: dog, domestic
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Gene
100295672 | KLRG1
Type: gene
Organism: cattle
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Gene
716727 | KLRG1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR042190 | KLRG1
Type: Family
Description: Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a co-inhibitory receptor inhibiting the activity of T and NK cells []. Its ligands include E-cadherin and N-cadherin. Binding of E-cadherin to KLRG1 has been shown to inhibits effector T-cell function [].
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Protein Coding Gene
MGI:1355294 | Klrg1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
34188973 | J:334818
First Author: Tata A
Year: 2021
Journal: Oncoimmunology
Title: Combination blockade of KLRG1 and PD-1 promotes immune control of local and disseminated cancers.
Volume: 10
Issue: 1
Pages: 1933808
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Publication
19604491 | -
First Author: Li Y
Year: 2009
Journal: Immunity
Title: Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.
Volume: 31
Issue: 1
Pages: 35-46
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Publication
28437578 | J:245227
First Author: Meinicke H
Year: 2017
Journal: Immunology
Title: KLRG1 impairs regulatory T-cell competitive fitness in the gut.
Volume: 152
Issue: 1
Pages: 65-73
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Publication
19009530 | J:141386
First Author: Rosshart S
Year: 2008
Journal: Eur J Immunol
Title: Interaction of KLRG1 with E-cadherin: new functional and structural insights.
Volume: 38
Issue: 12
Pages: 3354-64
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Publication
26014037 | J:229119
First Author: Schwartzkopff S
Year: 2015
Journal: Eur J Immunol
Title: TGF-β downregulates KLRG1 expression in mouse and human CD8(+) T cells.
Volume: 45
Issue: 8
Pages: 2212-7
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Publication
22684915 | J:187948
First Author: Hofmann M
Year: 2012
Journal: Eur J Immunol
Title: Different inhibitory capacities of human and mouse KLRG1 are linked to distinct disulfide-mediated oligomerizations.
Volume: 42
Issue: 9
Pages: 2484-90
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Publication
16140789 | J:101768
First Author: Thimme R
Year: 2005
Journal: J Virol
Title: Increased expression of the NK cell receptor KLRG1 by virus-specific CD8 T cells during persistent antigen stimulation.
Volume: 79
Issue: 18
Pages: 12112-6
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Publication
19855082 | J:155699
First Author: Banh C
Year: 2009
Journal: Blood
Title: Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling.
Volume: 114
Issue: 26
Pages: 5299-306
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Publication
17404256 | J:145204
First Author: Huntington ND
Year: 2007
Journal: J Immunol
Title: NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation.
Volume: 178
Issue: 8
Pages: 4764-70
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Publication
20201037 | J:160955
First Author: Gründemann C
Year: 2010
Journal: Eur J Immunol
Title: The NK receptor KLRG1 is dispensable for virus-induced NK and CD8+ T-cell differentiation and function in vivo.
Volume: 40
Issue: 5
Pages: 1303-14
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Publication
33914023 | J:343869
 
First Author: Hochheiser K
Year: 2021
Journal: J Exp Med
Title: Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin.
Volume: 218
Issue: 6
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Publication
19654330 | -
First Author: Nakamura S
Year: 2009
Journal: J Biol Chem
Title: Molecular basis for E-cadherin recognition by killer cell lectin-like receptor G1 (KLRG1).
Volume: 284
Issue: 40
Pages: 27327-35
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Publication
28011265 | J:241964
First Author: Montufar-Solis D
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Involvement of Ly6C, 4-1BB, and KLRG1 in the activation of lamina propria lymphocytes in the small intestine of sanroque mice.
Volume: 483
Issue: 1
Pages: 590-595
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Protein
O88713
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
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Publication
11220622 | J:65279
First Author: Voehringer D
Year: 2001
Journal: Immunogenetics
Title: Genomic structure, alternative splicing, and physical mapping of the killer cell lectin-like receptor G1 gene (KLRG1), the mouse homologue of MAFA.
Volume: 52
Issue: 3-4
Pages: 206-11
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Publication
23340310 | J:194060
First Author: Cyktor JC
Year: 2013
Journal: Infect Immun
Title: Killer cell lectin-like receptor G1 deficiency significantly enhances survival after Mycobacterium tuberculosis infection.
Volume: 81
Issue: 4
Pages: 1090-9
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Publication
24022692 | J:328702
First Author: Göthert JR
Year: 2013
Journal: Cancer Immunol Immunother
Title: Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1+ effector memory phenotype.
Volume: 62
Issue: 11
Pages: 1697-1709
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Publication
10741410 | J:60892
First Author: Corral L
Year: 2000
Journal: Eur J Immunol
Title: NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules.
Volume: 30
Issue: 3
Pages: 920-30
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Publication
29625895 | J:272661
First Author: Herndler-Brandstetter D
Year: 2018
Journal: Immunity
Title: KLRG1+ Effector CD8+ T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity.
Volume: 48
Issue: 4
Pages: 716-729.e8
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Publication
16424155 | J:126437
First Author: Gründemann C
Year: 2006
Journal: J Immunol
Title: Cutting edge: identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1.
Volume: 176
Issue: 3
Pages: 1311-5
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Publication
32611727 | J:300679
First Author: Renkema KR
Year: 2020
Journal: J Immunol
Title: KLRG1+ Memory CD8 T Cells Combine Properties of Short-Lived Effectors and Long-Lived Memory.
Volume: 205
Issue: 4
Pages: 1059-1069
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Publication
22786769 | J:189754
First Author: Cheng G
Year: 2012
Journal: J Immunol
Title: IL-2 receptor signaling is essential for the development of Klrg1+ terminally differentiated T regulatory cells.
Volume: 189
Issue: 4
Pages: 1780-91
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Publication
16461340 | J:118953
First Author: Ito M
Year: 2006
Journal: J Exp Med
Title: Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity.
Volume: 203
Issue: 2
Pages: 289-95
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Publication
36735533 | J:333440
First Author: Gurram RK
Year: 2023
Journal: Cell Rep
Title: Crosstalk between ILC2s and Th2 cells varies among mouse models.
Volume: 42
Issue: 2
Pages: 112073
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Publication
23436224 | J:329707
First Author: Tauro S
Year: 2013
Journal: Eur J Immunol
Title: Diversification and senescence of Foxp3+ regulatory T cells during experimental autoimmune encephalomyelitis.
Volume: 43
Issue: 5
Pages: 1195-207
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Protein Coding Gene
MGP_CAROLIEiJ_G0028819 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031222 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031121 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1355294 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031660 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030309 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030884 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031120 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031690 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030024 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030391 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022574 | -
Type: protein_coding_gene
Organism: Mus pahari
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Publication
9862378 | J:52111
First Author: Hanke T
Year: 1998
Journal: Eur J Immunol
Title: 2F1 antigen, the mouse homolog of the rat "mast cell function-associated antigen", is a lectin-like type II transmembrane receptor expressed by natural killer cells.
Volume: 28
Issue: 12
Pages: 4409-17
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Publication
9862665 | J:61061
First Author: Blaser C
Year: 1998
Journal: J Immunol
Title: Virus-activated CD8 T cells and lymphokine-activated NK cells express the mast cell function-associated antigen, an inhibitory C-type lectin.
Volume: 161
Issue: 12
Pages: 6451-4
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Publication
25118276 | J:214593
First Author: Shimizu K
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: KLRG+ invariant natural killer T cells are long-lived effectors.
Volume: 111
Issue: 34
Pages: 12474-9
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Publication
15210783 | J:90953
First Author: Robbins SH
Year: 2004
Journal: J Immunol
Title: Expansion and contraction of the NK cell compartment in response to murine cytomegalovirus infection.
Volume: 173
Issue: 1
Pages: 259-66
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Publication
18424713 | J:134314
First Author: Wilson DC
Year: 2008
Journal: J Immunol
Title: IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection.
Volume: 180
Issue: 9
Pages: 5935-45
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Publication
16384867 | J:108374
First Author: Vesper AH
Year: 2006
Journal: Endocrinology
Title: Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty.
Volume: 147
Issue: 4
Pages: 1654-63
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Publication
38897202 | J:354883
First Author: Burton OT
Year: 2024
Journal: Immunity
Title: The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program.
Volume: 57
Issue: 7
Pages: 1586-1602.e10
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Publication
19008372 | J:141393
First Author: Lin SL
Year: 2008
Journal: Am J Pathol
Title: Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney.
Volume: 173
Issue: 6
Pages: 1617-27
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Publication
24162776 | J:208724
First Author: Mackay LK
Year: 2013
Journal: Nat Immunol
Title: The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.
Volume: 14
Issue: 12
Pages: 1294-301
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Publication
23325888 | J:193405
First Author: Knell J
Year: 2013
Journal: J Immunol
Title: Id2 influences differentiation of killer cell lectin-like receptor G1(hi) short-lived CD8+ effector T cells.
Volume: 190
Issue: 4
Pages: 1501-9
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Publication
34764950 | J:357297
 
First Author: Yu M
Year: 2021
Journal: Front Immunol
Title: Single-Cell Sequencing Reveals the Novel Role of Ezh2 in NK Cell Maturation and Function.
Volume: 12
Pages: 724276
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Publication
18298548 | J:142779
First Author: Jänner N
Year: 2008
Journal: Immunology
Title: Restricted expression of C-type lectin-like natural killer receptors by CD8 T cells in the murine small intestine.
Volume: 125
Issue: 1
Pages: 38-47
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Publication
28437001 | J:246418
First Author: Meinicke H
Year: 2017
Journal: Immunology
Title: Tumour-associated changes in intestinal epithelial cells cause local accumulation of KLRG1+ GATA3+ regulatory T cells in mice.
Volume: 152
Issue: 1
Pages: 74-88
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Publication
22724066 | J:225105
First Author: Andrews TD
Year: 2012
Journal: Open Biol
Title: Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.
Volume: 2
Issue: 5
Pages: 120061
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Publication
26426795 | J:233774
First Author: Mathieu C
Year: 2015
Journal: Eur J Immunol
Title: IL-2 and IL-15 regulate CD8+ memory T-cell differentiation but are dispensable for protective recall responses.
Volume: 45
Issue: 12
Pages: 3324-38
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Publication
30301918 | J:278550
First Author: Böing M
Year: 2018
Journal: Sci Rep
Title: Murine transcription factor Math6 is a regulator of placenta development.
Volume: 8
Issue: 1
Pages: 14997
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Publication
27760760 | J:238745
First Author: Nishikii H
Year: 2016
Journal: Blood
Title: DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease.
Volume: 128
Issue: 24
Pages: 2846-2858
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Publication
23676498 | J:201437
First Author: Nagashima T
Year: 2013
Journal: J Clin Invest
Title: BMPR2 is required for postimplantation uterine function and pregnancy maintenance.
Volume: 123
Issue: 6
Pages: 2539-50
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Publication
- | J:104190
     
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Klrg1<em1(KLRG1)Smoc> | MGI:7290746
Name: killer cell lectin-like receptor subfamily G, member 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
17307799 | -
First Author: Tessmer MS
Year: 2007
Journal: Int Immunol
Title: KLRG1 binds cadherins and preferentially associates with SHIP-1.
Volume: 19
Issue: 4
Pages: 391-400
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Allele
Klrg1<em1Lbro> | MGI:7464198
Name: killer cell lectin-like receptor subfamily G, member 1; endonuclease-mediated mutation 1, Laurent Brossay
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Klrg1<tm1.1(EGFP/icre)Flv> | MGI:6357845
Name: killer cell lectin-like receptor subfamily G, member 1; targeted mutation 1.1, Richard A Flavell
Allele Type: Targeted
Attribute String: Recombinase, Reporter
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Strain
MGI:7464199 | C57BL/6-Klrg1<em1Lbro>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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MP Term
MP:0012768 | decreased KLRG1-positive NK cell number
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MP Term
MP:0012767 | increased KLRG1-positive NK cell number
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