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Search results 1 to 100 out of 362 for Kmt2c

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0.044s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Histone-lysine N-methyltransferases 2C (also known as MLL3) methylates 'Lys-4' of histone H3 (H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation). It is a component of the MLL2/3 complex [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Lee S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.
Volume: 103
Issue: 42
Pages: 15392-7
Publication
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
Publication
First Author: Limberger T
Year: 2022
Journal: Mol Cancer
Title: KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.
Volume: 21
Issue: 1
Pages: 89
Publication
First Author: Gala K
Year: 2018
Journal: Oncogene
Title: KMT2C mediates the estrogen dependence of breast cancer through regulation of ERĪ± enhancer function.
Volume: 37
Issue: 34
Pages: 4692-4710
Publication
First Author: Chen R
Year: 2021
Journal: Cell Rep
Title: Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy.
Volume: 34
Issue: 7
Pages: 108751
Protein
Organism: Mus musculus/domesticus
Length: 1524  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1748  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1520  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 4903  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 4904  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 865  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 722  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1716  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 563  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 813  
Fragment?: true
Publication
First Author: Valekunja UK
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Histone methyltransferase MLL3 contributes to genome-scale circadian transcription.
Volume: 110
Issue: 4
Pages: 1554-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Brun ME
Year: 2006
Journal: Gene
Title: Characterization and expression analysis during embryo development of the mouse ortholog of MLL3.
Volume: 371
Issue: 1
Pages: 25-33
Publication      
First Author: Lee J
Year: 2011
Journal: MGI Direct Data Submission
Title: The frt-flanked neo cassette has been removed from Mll3tm1.2Jwle
Publication
First Author: Arcipowski KM
Year: 2016
Journal: PLoS One
Title: Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis.
Volume: 11
Issue: 9
Pages: e0162515
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal adult
Specimen Label: Heart
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5604267
Age: embryonic day 11.5
Specimen Label: 11.5 dpc
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal day 5
Specimen Label: 5 dpp Testis
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal day 8
Specimen Label: 8 dpp Testis
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal day 11
Specimen Label: 11 dpp Testis
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal day 14
Specimen Label: 14 dpp Testis
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal day 18
Specimen Label: 18 dpp Testis
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal day 22
Specimen Label: 22 dpp Testis
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal day 29
Specimen Label: 29 dpp Testis
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Female
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:5604267
Age: embryonic day 11.5
Specimen Label: 11.5 dpc
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Female
Emaps: EMAPS:1796224
Stage: TS24
Assay Id: MGI:5604267
Age: embryonic day 16.5
Specimen Label: 16.5 dpc Ovary
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:5604012
Assay Type: RT-PCR
Annotation Date: 2014-11-13
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5604267
Age: postnatal day 4
Specimen Label: 4 dpp Ovary
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:3831391
Assay Type: RT-PCR
Annotation Date: 2009-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3831398
Age: embryonic day 13.5
Image: 3
Specimen Label: WAT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3831391
Assay Type: RT-PCR
Annotation Date: 2009-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3831398
Age: embryonic day 13.5
Image: 3
Specimen Label: BAT
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611814
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:5604015
Age: embryonic day 9.0
Specimen Label: 2b
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5604015
Age: embryonic day 9.5
Specimen Label: 2c
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691621
Stage: TS21
Assay Id: MGI:3508318
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:3008123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539865
Age: embryonic day 15.5
Image: GUDMAP:13871
Specimen Label: GUDMAP:13871
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Present
Sex: Female
Emaps: EMAPS:1796521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5604015
Age: embryonic day 13.5
Note: Clumps of positive cells correspond to the germ cells.
Specimen Label: 2l
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777821
Stage: TS21
Assay Id: MGI:3508318
Age: embryonic day 13.5
Image: 1
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5604015
Age: embryonic day 10.5
Specimen Label: 2d
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679916
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:5604015
Age: embryonic day 10.0
Specimen Label: 2e eye E10
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666522
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619822
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1619812
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5604015
Age: embryonic day 8.0
Note: Expression was stronger in the forming optic placodes.
Specimen Label: 2a
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619821
Stage: TS21
Assay Id: MGI:5604015
Age: embryonic day 13.5
Specimen Label: 2f
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754921
Stage: TS21
Assay Id: MGI:3508318
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754922
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Note: Expression was not detected in the corpus striatum (lateral ganglionic eminence).
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697421
Stage: TS21
Assay Id: MGI:3508318
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697422
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5604015
Age: embryonic day 10.5
Note: Expression was detected in the ventral midbrain.
Specimen Label: 2d
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539865
Age: embryonic day 15.5
Image: GUDMAP:6258
Specimen Label: GUDMAP:6258
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276322
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Note: Expression was not detected in the face/soft tissues.
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539865
Age: embryonic day 15.5
Image: GUDMAP:13871
Specimen Label: GUDMAP:13871
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2021-03-31
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3152723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6513931
Age: embryonic day 15.5
Note: Very weak staining was observed, indicating potential expression.
Specimen Label: Table S1 - Mll3
Specimen Num: 1
GXD Expression  
Probe: MGI:5604010
Assay Type: RNA in situ
Annotation Date: 2014-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1678119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5604015
Age: embryonic day 11.5
Note: Expression was detected in the hindlimb mesoderm.
Specimen Label: 2e
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1783822
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506899
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665921
Stage: TS21
Assay Id: MGI:3508318
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4422651
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665922
Stage: TS22
Assay Id: MGI:5422049
Age: embryonic day 14.5
Specimen Label: EN1243; Specimen N540
Detected: false
Specimen Num: 1