Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3837150 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-06-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1775521 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6162509 |
Age: |
embryonic day 13.0 |
Image: |
2A Lama2 WT |
Note: |
Expression in subepithelial basement membranes. |
Specimen Label: |
2A Lama2 WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3837150 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-06-26 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1775521 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6162509 |
Age: |
embryonic day 13.0 |
Image: |
2A Lama2 Lama5-/- |
Note: |
Authors report no increase in expression in subepithelial basement membrane. |
Specimen Label: |
2A Lama2 Lama5-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wolfe HG |
Year: |
1962 |
Journal: |
Mouse News Lett |
Title: |
Lama2 |
Volume: |
26 |
|
Pages: |
36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patton BL |
Year: |
2008 |
Journal: |
J Cell Sci |
Title: |
A single point mutation in the LN domain of LAMA2 causes muscular dystrophy and peripheral amyelination. |
Volume: |
121 |
Issue: |
Pt 10 |
Pages: |
1593-604 |
|
•
•
•
•
•
|
Publication |
First Author: |
Biswas S |
Year: |
2022 |
Journal: |
Development |
Title: |
Mural Wnt/β-catenin signaling regulates Lama2 expression to promote neurovascular unit maturation. |
Volume: |
149 |
Issue: |
17 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kuang W |
Year: |
1999 |
Journal: |
Lab Invest |
Title: |
Activation of the lama2 gene in muscle regeneration: abortive regeneration in laminin alpha2-deficiency. |
Volume: |
79 |
Issue: |
12 |
Pages: |
1601-13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877126 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:7488620 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
1b Lama2 E18.5 EKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877128 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7488620 |
Age: |
postnatal day 10 |
|
Note: |
Expression restricted to lower part of hair follicles. |
Specimen Label: |
1b Lama2 P10 control |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488572 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752527 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7488654 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
S1a Lama2 WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3823326 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:7488620 |
Age: |
embryonic day 18.5 |
|
Note: |
Prominent continuous expression at dermo-epidermal junction (DEJ). |
Specimen Label: |
1b Lama2 E18.5 EKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488572 |
Assay Type: |
RNA in situ |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3823327 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7488654 |
Age: |
postnatal day 1 |
|
Note: |
Promiment expression at dermo-epidermal junction. |
Specimen Label: |
S1a Lama2 EKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877127 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:7488620 |
Age: |
postnatal day 1 |
|
Note: |
Expression restricted to lower part of hair follicles. |
Specimen Label: |
1b Lama2 P1 control |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877127 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:7488620 |
Age: |
postnatal day 1 |
|
|
Specimen Label: |
1b Lama2 P1 EKO |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1877128 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7488620 |
Age: |
postnatal day 10 |
|
|
Specimen Label: |
1b Lama2 P10 EKO |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3639226 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:7488620 |
Age: |
embryonic day 18.5 |
|
Note: |
Expression restricted to lower part of hair follicles. |
Specimen Label: |
1b Lama2 E18.5 control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3823327 |
Pattern: |
Regionally restricted |
Stage: |
TS27 |
Assay Id: |
MGI:7488620 |
Age: |
postnatal day 1 |
|
Note: |
Prominent continuous expression at dermo-epidermal junction (DEJ). |
Specimen Label: |
1b Lama2 P1 EKO |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7488554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-06-12 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3823328 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7488620 |
Age: |
postnatal day 10 |
|
Note: |
Prominent continuous expression at dermo-epidermal junction (DEJ). |
Specimen Label: |
1b Lama2 P10 EKO |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kuang W |
Year: |
1998 |
Journal: |
Exp Cell Res |
Title: |
Disruption of the lama2 gene in embryonic stem cells: laminin alpha 2 is necessary for sustenance of mature muscle cells. |
Volume: |
241 |
Issue: |
1 |
Pages: |
117-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyagoe Y |
Year: |
1997 |
Journal: |
FEBS Lett |
Title: |
Laminin alpha2 chain-null mutant mice by targeted disruption of the Lama2 gene: a new model of merosin (laminin 2)-deficient congenital muscular dystrophy. |
Volume: |
415 |
Issue: |
1 |
Pages: |
33-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mukasa T |
Year: |
1999 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Activation of caspase-3 apoptotic pathways in skeletal muscle fibers in laminin alpha2-deficient mice. |
Volume: |
260 |
Issue: |
1 |
Pages: |
139-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sewry CA |
Year: |
1998 |
Journal: |
Neuropathol Appl Neurobiol |
Title: |
Differential labelling of laminin alpha 2 in muscle and neural tissue of dy/dy mice: are there isoforms of the laminin alpha 2 chain? |
Volume: |
24 |
Issue: |
1 |
Pages: |
66-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vilquin JT |
Year: |
1996 |
Journal: |
J Cell Biol |
Title: |
Partial laminin alpha2 chain restoration in alpha2 chain-deficient dy/dy mouse by primary muscle cell culture transplantation. |
Volume: |
133 |
Issue: |
1 |
Pages: |
185-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Besse S |
Year: |
2003 |
Journal: |
Neuromuscul Disord |
Title: |
Spontaneous muscular dystrophy caused by a retrotransposal insertion in the mouse laminin alpha2 chain gene. |
Volume: |
13 |
Issue: |
3 |
Pages: |
216-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rasminsky M |
Year: |
1978 |
Journal: |
Brain Res |
Title: |
Conduction of nervous impulses in spinal roots and peripheral nerves of dystrophic mice. |
Volume: |
143 |
Issue: |
1 |
Pages: |
71-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ukai M |
Year: |
1993 |
Journal: |
Biomed Res |
Title: |
Postnatal changes in the extrafusal muscle fiber and muscle spindle in the masseter muscle of the dystrophic mouse. |
Volume: |
14 |
Issue: |
6 |
Pages: |
419-425 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lucas-Heron B |
Year: |
1997 |
Journal: |
Biochem Biophys Res Commun |
Title: |
A drug inhibits the mitochondrial protease inducing calmitine deficiency in skeletal muscle of patients with Duchenne's muscular dystrophy and dy/dy dystrophic mice. |
Volume: |
232 |
Issue: |
2 |
Pages: |
559-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu H |
Year: |
1994 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Defective muscle basement membrane and lack of M-laminin in the dystrophic dy/dy mouse. |
Volume: |
91 |
Issue: |
12 |
Pages: |
5572-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLane JA |
Year: |
1977 |
Journal: |
J Neurochem |
Title: |
Rapid axoplasmic transport in dystrophic mice. |
Volume: |
29 |
Issue: |
5 |
Pages: |
865-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sorokin LM |
Year: |
2000 |
Journal: |
Exp Cell Res |
Title: |
Laminin alpha4 and integrin alpha6 are upregulated in regenerating dy/dy skeletal muscle: comparative expression of laminin and integrin isoforms in muscles regenerating after crush injury. |
Volume: |
256 |
Issue: |
2 |
Pages: |
500-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vilquin JT |
Year: |
1999 |
Journal: |
Gene Ther |
Title: |
Myoblast transplantations lead to the expression of the laminin alpha 2 chain in normal and dystrophic (dy/dy) mouse muscles. |
Volume: |
6 |
Issue: |
5 |
Pages: |
792-800 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arahata K |
Year: |
1993 |
Journal: |
Proc Jpn Acad |
Title: |
Laminin in animal models for muscular dystrophy - defect of Laminin-M in skeletal and cardiac muscles and peripheral nerve of the homozygous dystrophic dy/dy mice |
Volume: |
69 (Series B) |
Issue: |
10 |
Pages: |
259-264 |
|
•
•
•
•
•
|
Publication |
First Author: |
Harris JB |
Year: |
1978 |
Journal: |
Nature |
Title: |
Neuromuscular transmission is adequate in identified abnormal dystrophic muscle fibres. |
Volume: |
271 |
Issue: |
5643 |
Pages: |
362-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Madrid RE |
Year: |
1975 |
Journal: |
Nature |
Title: |
Genetically determined defect of Schwann cell basement membrane in dystrophic mouse. |
Volume: |
257 |
Issue: |
5524 |
Pages: |
319-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carbonetto S |
Year: |
1977 |
Journal: |
J Neurophysiol |
Title: |
Neuromuscular transmission in dystrophic mice. |
Volume: |
40 |
Issue: |
4 |
Pages: |
836-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brimijoin S |
Year: |
1976 |
Journal: |
Exp Neurol |
Title: |
Reduced axonal transport of dopamine-beta-hydroxylase activity in dystrophic mice: evidence for abnormality of adrenergic nerve cells. |
Volume: |
53 |
Issue: |
2 |
Pages: |
454-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bourke DL |
Year: |
1986 |
Journal: |
Anat Rec |
Title: |
Modification of the phenotypic expression of murine dystrophy: a morphological study. |
Volume: |
214 |
Issue: |
1 |
Pages: |
17-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moral-Naranjo MT |
Year: |
2002 |
Journal: |
Neurosci Lett |
Title: |
Muscular dystrophy with laminin deficiency decreases the content of butyrylcholinesterase tetramers in sciatic nerves of Lama2dy mice. |
Volume: |
331 |
Issue: |
3 |
Pages: |
155-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Lunteren E |
Year: |
2006 |
Journal: |
Physiol Genomics |
Title: |
Gene expression profiling of diaphragm muscle in alpha2-laminin (merosin)-deficient dy/dy dystrophic mice. |
Volume: |
25 |
Issue: |
1 |
Pages: |
85-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bradley WG |
Year: |
1977 |
Journal: |
J Neuropathol Exp Neurol |
Title: |
The nodes of Ranvier in the nerves of mice with muscular dystrophy. |
Volume: |
36 |
Issue: |
5 |
Pages: |
797-806 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jaros E |
Year: |
1979 |
Journal: |
Neuropathol Appl Neurobiol |
Title: |
Atypical axon-Schwann cell relationships in the common peroneal nerve of the dystrophic mouse: an ultrastructural study. |
Volume: |
5 |
Issue: |
2 |
Pages: |
133-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Relan NK |
Year: |
1999 |
Journal: |
J Cell Biol |
Title: |
Cell elongation induces laminin alpha2 chain expression in mouse embryonic mesenchymal cells: role in visceral myogenesis. |
Volume: |
147 |
Issue: |
6 |
Pages: |
1341-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dubowitz DJ |
Year: |
2000 |
Journal: |
Neuromuscul Disord |
Title: |
High resolution magnetic resonance imaging of the brain in the dy/dy mouse with merosin-deficient congenital muscular dystrophy. |
Volume: |
10 |
Issue: |
4-5 |
Pages: |
292-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Michelson AM |
Year: |
1955 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Dystrophia Muscularis: A HEREDITARY PRIMARY MYOPATHY IN THE HOUSE MOUSE. |
Volume: |
41 |
Issue: |
12 |
Pages: |
1079-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jucker M |
Year: |
1996 |
Journal: |
Neuroscience |
Title: |
Laminin alpha 2 is a component of brain capillary basement membrane: reduced expression in dystrophic dy mice. |
Volume: |
71 |
Issue: |
4 |
Pages: |
1153-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Neerunjun JS |
Year: |
1977 |
Journal: |
J Anat |
Title: |
Regeneration of muscles transplanted between normal and dystrophic mice: a quantitative study of early transplants. |
Volume: |
124 |
Issue: |
Pt 2 |
Pages: |
459-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jaros E |
Year: |
1983 |
Journal: |
Brain Res |
Title: |
Defective differentiation of peripheral nerves in the dystrophic mouse. |
Volume: |
282 |
Issue: |
3 |
Pages: |
231-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsuji S |
Year: |
1985 |
Journal: |
J Neurol Sci |
Title: |
Evidence on hypomyelination of central nervous system in murine muscular dystrophy. |
Volume: |
68 |
Issue: |
2-3 |
Pages: |
175-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moral-Naranjo MT |
Year: |
2010 |
Journal: |
Biochim Biophys Acta |
Title: |
The levels of both lipid rafts and raft-located acetylcholinesterase dimers increase in muscle of mice with muscular dystrophy by merosin deficiency. |
Volume: |
1802 |
Issue: |
9 |
Pages: |
754-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Montgomery A |
Year: |
1975 |
Journal: |
J Neurol Sci |
Title: |
Parabiotic reinnervation in normal and dystrophic mice. Part 1. Muscle weight and physiological studies. |
Volume: |
26 |
Issue: |
3 |
Pages: |
401-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cabezas-Herrera J |
Year: |
1997 |
Journal: |
J Neurochem |
Title: |
Glycosylation of acetylcholinesterase forms in microsomal membranes from normal and dystrophic Lama2dy mouse muscle. |
Volume: |
69 |
Issue: |
5 |
Pages: |
1964-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nieto-Cerón S |
Year: |
2005 |
Journal: |
J Neurochem |
Title: |
Muscular dystrophy by merosin deficiency decreases acetylcholinesterase activity in thymus of Lama2dy mice. |
Volume: |
95 |
Issue: |
4 |
Pages: |
1035-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moral-Naranjo MT |
Year: |
1999 |
Journal: |
J Neurochem |
Title: |
Increased butyrylcholinesterase levels in microsomal membranes of dystrophic Lama2dy mouse muscle. |
Volume: |
73 |
Issue: |
3 |
Pages: |
1138-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ontell MP |
Year: |
1992 |
Journal: |
J Neurobiol |
Title: |
Transient neonatal denervation alters the proliferative capacity of myosatellite cells in dystrophic (129ReJdy/dy) muscle. |
Volume: |
23 |
Issue: |
4 |
Pages: |
407-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Lunteren E |
Year: |
2003 |
Journal: |
Pediatr Res |
Title: |
Sternohyoid muscle fatigue properties of dy/dy dystrophic mice, an animal model of merosin-deficient congenital muscular dystrophy. |
Volume: |
54 |
Issue: |
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