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Search results 1 to 100 out of 347 for Lrig1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Kondo J
Year: 2015
Journal: Gastroenterology
Title: LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice.
Volume: 149
Issue: 2
Pages: 407-19.e8
Publication
First Author: Nam HS
Year: 2020
Journal: Neural Dev
Title: Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life.
Volume: 15
Issue: 1
Pages: 3
Publication
First Author: Wang Y
Year: 2015
Journal: Am J Pathol
Title: Loss of Lrig1 leads to expansion of Brunner glands followed by duodenal adenomas with gastric metaplasia.
Volume: 185
Issue: 4
Pages: 1123-34
Publication
First Author: Powell AE
Year: 2012
Journal: Cell
Title: The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor.
Volume: 149
Issue: 1
Pages: 146-58
Publication
First Author: Chen X
Year: 2019
Journal: J Exp Med
Title: IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells.
Volume: 216
Issue: 1
Pages: 195-214
Publication
First Author: Liakath-Ali K
Year: 2018
Journal: Nature
Title: An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.
Volume: 556
Issue: 7701
Pages: 376-380
Publication
First Author: Choi E
Year: 2018
Journal: Gut
Title: Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach.
Volume: 67
Issue: 9
Pages: 1595-1605
Publication
First Author: Wroblewski LE
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Targeted mobilization of Lrig1+ gastric epithelial stem cell populations by a carcinogenic Helicobacter pylori type IV secretion system.
Volume: 116
Issue: 39
Pages: 19652-19658
Publication
First Author: Wang MT
Year: 2015
Journal: Cell
Title: K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling.
Volume: 163
Issue: 5
Pages: 1237-1251
Publication
First Author: Barnes L
Year: 2017
Journal: PLoS One
Title: Senescent Atrophic Epidermis Retains Lrig1+ Stem Cells and Loses Wnt Signaling, a Phenotype Shared with CD44KO Mice.
Volume: 12
Issue: 1
Pages: e0169452
Publication
First Author: Jeong D
Year: 2020
Journal: Cell Rep
Title: LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex.
Volume: 33
Issue: 2
Pages: 108257
Publication
First Author: Page ME
Year: 2013
Journal: Cell Stem Cell
Title: The epidermis comprises autonomous compartments maintained by distinct stem cell populations.
Volume: 13
Issue: 4
Pages: 471-82
Publication  
First Author: Lichtenberger BM
Year: 2016
Journal: Nat Commun
Title: Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages.
Volume: 7
Pages: 10537
Publication
First Author: Kretzschmar K
Year: 2014
Journal: Stem Cell Reports
Title: BLIMP1 is required for postnatal epidermal homeostasis but does not define a sebaceous gland progenitor under steady-state conditions.
Volume: 3
Issue: 4
Pages: 620-33
Publication
First Author: Donati G
Year: 2017
Journal: Nat Cell Biol
Title: Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties.
Volume: 19
Issue: 6
Pages: 603-613
Publication
First Author: Rognoni E
Year: 2016
Journal: Development
Title: Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.
Volume: 143
Issue: 14
Pages: 2522-35
Publication
First Author: Driskell RR
Year: 2013
Journal: Nature
Title: Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Volume: 504
Issue: 7479
Pages: 277-281
Publication      
First Author: Lim SBH
Year: 2022
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Conditional Scd1 Allele Activated in Hair Follicles
Publication
First Author: Swanson JB
Year: 2019
Journal: Exp Dermatol
Title: Loss of Gata6 causes dilation of the hair follicle canal and sebaceous duct.
Volume: 28
Issue: 4
Pages: 345-349
Publication
First Author: Powell AE
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.
Volume: 307
Issue: 1
Pages: G16-23
Publication
First Author: Herring CA
Year: 2018
Journal: Cell Syst
Title: Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut.
Volume: 6
Issue: 1
Pages: 37-51.e9
Publication
First Author: Choi E
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Active Kras Expression in Gastric Isthmal Progenitor Cells Induces Foveolar Hyperplasia but Not Metaplasia.
Volume: 7
Issue: 1
Pages: 251-253.e1
Publication
First Author: Zhang Q
Year: 2019
Journal: Cell Rep
Title: Transfer of Functional Cargo in Exomeres.
Volume: 27
Issue: 3
Pages: 940-954.e6
Publication
First Author: Means AL
Year: 2018
Journal: Cell Mol Gastroenterol Hepatol
Title: Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer.
Volume: 6
Issue: 3
Pages: 257-276
Publication
First Author: Bensard CL
Year: 2020
Journal: Cell Metab
Title: Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.
Volume: 31
Issue: 2
Pages: 284-300.e7
Publication
First Author: Trieu KG
Year: 2022
Journal: Cell Rep
Title: Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease.
Volume: 39
Issue: 5
Pages: 110779
Publication
First Author: Vázquez-Arreguín K
Year: 2019
Journal: PLoS Genet
Title: Oct1/Pou2f1 is selectively required for colon regeneration and regulates colon malignancy.
Volume: 15
Issue: 5
Pages: e1007687
Publication
First Author: Jones KB
Year: 2019
Journal: Cell Stem Cell
Title: Quantitative Clonal Analysis and Single-Cell Transcriptomics Reveal Division Kinetics, Hierarchy, and Fate of Oral Epithelial Progenitor Cells.
Volume: 24
Issue: 1
Pages: 183-192.e8
Publication
First Author: Kodama T
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM.
Volume: 116
Issue: 47
Pages: 23625-23635
Publication
First Author: Marincola Smith P
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice.
Volume: 320
Issue: 6
Pages: G936-G957
Publication      
First Author: Thompson JJ
Year: 2019
Journal: Carcinogenesis
Title: Blood vessel epicardial substance (BVES) reduces LRP6 receptor and cytoplasmic -catenin levels to modulate Wnt signaling and intestinal homeostasis.
Publication
First Author: Veniaminova NA
Year: 2019
Journal: Dev Cell
Title: Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin.
Volume: 51
Issue: 3
Pages: 326-340.e4
Publication
First Author: Eberl M
Year: 2018
Journal: Cancer Cell
Title: Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma.
Volume: 33
Issue: 2
Pages: 229-243.e4
Publication
First Author: Choi E
Year: 2015
Journal: Am J Pathol
Title: Dynamic expansion of gastric mucosal doublecortin-like kinase 1-expressing cells in response to parietal cell loss is regulated by gastrin.
Volume: 185
Issue: 8
Pages: 2219-31
Publication
First Author: Sharir A
Year: 2019
Journal: Nat Cell Biol
Title: A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage.
Volume: 21
Issue: 9
Pages: 1102-1112
Publication
First Author: Sakamoto K
Year: 2021
Journal: Immunity
Title: Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction.
Volume: 54
Issue: 10
Pages: 2321-2337.e10
Publication
First Author: Peterson SC
Year: 2015
Journal: Cell Stem Cell
Title: Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches.
Volume: 16
Issue: 4
Pages: 400-12
Publication
First Author: Cheung P
Year: 2020
Journal: Cell Stem Cell
Title: Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer.
Volume: 27
Issue: 4
Pages: 590-604.e9
Publication
First Author: Veniaminova NA
Year: 2013
Journal: Development
Title: Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration.
Volume: 140
Issue: 24
Pages: 4870-80
Publication
First Author: Mao F
Year: 2018
Journal: Oncogenesis
Title: Lrig1 is a haploinsufficient tumor suppressor gene in malignant glioma.
Volume: 7
Issue: 2
Pages: 13
Publication
First Author: Nakamura T
Year: 2014
Journal: J Clin Invest
Title: LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis.
Volume: 124
Issue: 1
Pages: 385-97
Publication
First Author: Alsina FC
Year: 2016
Journal: EMBO Rep
Title: Lrig1 is a cell-intrinsic modulator of hippocampal dendrite complexity and BDNF signaling.
Volume: 17
Issue: 4
Pages: 601-16
Publication
First Author: Wang Y
Year: 2013
Journal: Br J Cancer
Title: LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor.
Volume: 108
Issue: 9
Pages: 1765-70
Publication
First Author: Miller JK
Year: 2008
Journal: Cancer Res
Title: Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer.
Volume: 68
Issue: 20
Pages: 8286-94
Publication
First Author: Jensen KB
Year: 2009
Journal: Cell Stem Cell
Title: Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis.
Volume: 4
Issue: 5
Pages: 427-39
Publication
First Author: Schweiger PJ
Year: 2018
Journal: Sci Rep
Title: Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro.
Volume: 8
Issue: 1
Pages: 15255
Publication  
First Author: De Vincenti AP
Year: 2021
Journal: Development
Title: Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation.
Volume: 148
Issue: 16
Publication
First Author: Wong VW
Year: 2012
Journal: Nat Cell Biol
Title: Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling.
Volume: 14
Issue: 4
Pages: 401-8
Publication
First Author: Ledda F
Year: 2008
Journal: J Neurosci
Title: Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF.
Volume: 28
Issue: 1
Pages: 39-49
Publication
First Author: Niitsu H
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Cell-Autonomous Role of EGFR in Spontaneous Duodenal Tumors in LRIG1 Null Mice.
Volume: 12
Issue: 3
Pages: 1159-1162.e4
Allele
Name: leucine-rich repeats and immunoglobulin-like domains 1; targeted mutation 1, Kim B Jensen
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Genotype
Symbol: Lrig1/Lrig1<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
Allele
Name: leucine-rich repeats and immunoglobulin-like domains 1; targeted mutation 2.1, Mario R Capecchi
Allele Type: Targeted
Attribute String: Recombinase
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele
Name: leucine-rich repeats and immunoglobulin-like domains 1; targeted mutation 1.1, Robert J Coffey
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Strain
Attribute String: congenic, mutant strain, targeted mutation
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Apc/Apc<+> Lrig1/Lrig1<+>
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Lgr5/Lgr5<+> Lrig1/Lrig1
Background: involves: 129 * 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Lrig1/Lrig1
Background: involves: 129 * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Scd1/Scd1 Lrig1/Lrig1<+>
Background: B6.129(Cg)-Lrig1 Scd1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Lrig1/Lrig1<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Lrig1/Lrig1<+>
Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Lrig1/Lrig1<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Lrig1/Lrig1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus
Length: 1042  
Fragment?: false
Publication
First Author: Yu S
Year: 2018
Journal: Am J Pathol
Title: Expression of LRIG1, a Negative Regulator of EGFR, Is Dynamically Altered during Different Stages of Gastric Carcinogenesis.
Volume: 188
Issue: 12
Pages: 2912-2923
Publication
First Author: Del Rio T
Year: 2013
Journal: PLoS Genet
Title: In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear.
Volume: 9
Issue: 9
Pages: e1003824
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Suzuki Y
Year: 2002
Journal: FEBS Lett
Title: Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia.
Volume: 521
Issue: 1-3
Pages: 67-71
Publication
First Author: Nilsson J
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Cloning, characterization, and expression of human LIG1.
Volume: 284
Issue: 5
Pages: 1155-61
GXD Expression    
Probe: MGI:7258001
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Stage: TS25
Assay Id: MGI:7258011
Age: embryonic day 17.0
Image: 2
Specimen Label: E17
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7258001
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:7258011
Age: postnatal day 0
Image: 2
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7258001
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:7258011
Age: postnatal day 7
Image: 2
Specimen Label: P7
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7258001
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:7258011
Age: postnatal day 14
Image: 2
Specimen Label: P14
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7258001
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:7258011
Age: postnatal day 21
Image: 2
Specimen Label: P21
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7258001
Assay Type: RT-PCR
Annotation Date: 2022-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Stage: TS28
Assay Id: MGI:7258011
Age: postnatal adult
Image: 2
Specimen Label: Ad
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3724371
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5421031
Age: embryonic day 14.5
Specimen Label: MH431; Specimen C1079
Detected: false
Specimen Num: 1