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Search results 1 to 100 out of 891 for Lrp5

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
key_1584452 | Lrp5
Type: gene
Organism: Not Specified
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Gene
4041 | LRP5
Type: gene
Organism: human
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Gene
534450 | LRP5
Type: gene
Organism: cattle
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Gene
100306933 | LRP5
Type: gene
Organism: dog, domestic
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Gene
423114 | LRP5
Type: gene
Organism: chicken
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Gene
568518 | lrp5
Type: gene
Organism: zebrafish
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Gene
721605 | LRP5
Type: gene
Organism: macaque, rhesus
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Gene
100491803 | lrp5
Type: gene
Organism: frog, western clawed
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Gene
293649 | Lrp5
Type: gene
Organism: rat
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Gene
451380 | LRP5
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1278315 | Lrp5
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1737322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3276322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Note: Expression was weak in Face/Soft Tissues.
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1783822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1665922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1706822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1674822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1738222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1755022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1733122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3290622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1745822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3278022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3286922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1752322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3277822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1685322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1718522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1750322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1775122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3287422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1736222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1832122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1741222
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3599822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1821522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1702122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1756322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1668822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3724672
Assay Type: RNA in situ
Annotation Date: 2008-01-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3766957
Age: embryonic day 14.5
Image: 5 Lrp5
Specimen Label: 5 Lrp5
Detected: true
Specimen Num: 1
•
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•
•
Publication
15207752 | J:128871
First Author: Akhter MP
Year: 2004
Journal: Bone
Title: Bone biomechanical properties in LRP5 mutant mice.
Volume: 35
Issue: 1
Pages: 162-9
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Publication
20652025 | J:163107
First Author: Xia CH
Year: 2010
Journal: PLoS One
Title: LRP5 is required for vascular development in deeper layers of the retina.
Volume: 5
Issue: 7
Pages: e11676
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Publication
22303459 | J:184212
First Author: Shahi P
Year: 2012
Journal: PLoS One
Title: Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.
Volume: 7
Issue: 1
Pages: e30814
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Publication
21602802 | J:172746
First Author: Cui Y
Year: 2011
Journal: Nat Med
Title: Lrp5 functions in bone to regulate bone mass.
Volume: 17
Issue: 6
Pages: 684-91
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Publication
27031698 | J:249149
First Author: Huang W
Year: 2016
Journal: PLoS One
Title: Critical Endothelial Regulation by LRP5 during Retinal Vascular Development.
Volume: 11
Issue: 3
Pages: e0152833
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Publication
28158288 | J:247144
First Author: Sun T
Year: 2017
Journal: PLoS One
Title: miR-375-3p negatively regulates osteogenesis by targeting and decreasing the expression levels of LRP5 and β-catenin.
Volume: 12
Issue: 2
Pages: e0171281
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Publication
29899194 | J:273687
First Author: Li L
Year: 2018
Journal: Biosci Trends
Title: Heterozygous deletion of LRP5 gene in mice alters profile of immune cells and modulates differentiation of osteoblasts.
Volume: 12
Issue: 3
Pages: 266-274
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Publication
17627087 | J:126821
First Author: Dubrow SA
Year: 2007
Journal: J Musculoskelet Neuronal Interact
Title: Gender specific LRP5 influences on trabecular bone structure and strength.
Volume: 7
Issue: 2
Pages: 166-73
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Publication
12817748 | J:111467
First Author: Babij P
Year: 2003
Journal: J Bone Miner Res
Title: High bone mass in mice expressing a mutant LRP5 gene.
Volume: 18
Issue: 6
Pages: 960-74
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Publication
24058663 | J:207341
First Author: Xia CH
Year: 2013
Journal: PLoS One
Title: Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization.
Volume: 8
Issue: 9
Pages: e75186
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Publication
21866564 | J:179033
First Author: Zhong Z
Year: 2012
Journal: J Cell Biochem
Title: Lrp5 and Lrp6 play compensatory roles in mouse intestinal development.
Volume: 113
Issue: 1
Pages: 31-8
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Publication
16790443 | J:116515
First Author: Sawakami K
Year: 2006
Journal: J Biol Chem
Title: The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment.
Volume: 281
Issue: 33
Pages: 23698-711
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Publication
25808845 | J:278576
First Author: Niziolek PJ
Year: 2015
Journal: J Bone Miner Res
Title: High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo.
Volume: 30
Issue: 10
Pages: 1822-30
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Publication
19041748 | J:146078
First Author: Yadav VK
Year: 2008
Journal: Cell
Title: Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum.
Volume: 135
Issue: 5
Pages: 825-37
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Publication
30409757 | J:270185
 
First Author: Kang KS
Year: 2019
Journal: Bone
Title: Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism.
Volume: 120
Pages: 166-175
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Publication
29176883 | J:251515
First Author: Sebastian A
Year: 2017
Journal: PLoS One
Title: Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.
Volume: 12
Issue: 11
Pages: e0188264
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Publication
29123193 | J:253571
First Author: Weaver SR
Year: 2017
Journal: Sci Rep
Title: Characterization of mammary-specific disruptions for Tph1 and Lrp5 during murine lactation.
Volume: 7
Issue: 1
Pages: 15155
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Publication
22359381 | J:327853
First Author: Rajamannan NM
Year: 2012
Journal: J Cell Biochem
Title: Oxidative-mechanical stress signals stem cell niche mediated Lrp5 osteogenesis in eNOS(-/-) null mice.
Volume: 113
Issue: 5
Pages: 1623-34
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Publication
21924256 | J:178499
First Author: Joeng KS
Year: 2011
Journal: Dev Biol
Title: Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo.
Volume: 359
Issue: 2
Pages: 222-9
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Publication
23675479 | J:202175
First Author: Riddle RC
Year: 2013
Journal: PLoS One
Title: Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.
Volume: 8
Issue: 5
Pages: e63323
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Publication
22848540 | J:189700
First Author: Mammoto T
Year: 2012
Journal: PLoS One
Title: LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway.
Volume: 7
Issue: 7
Pages: e41596
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Publication
26711269 | J:236204
First Author: Chin EN
Year: 2015
Journal: Mol Cell Biol
Title: Lrp5 Has a Wnt-Independent Role in Glucose Uptake and Growth for Mammary Epithelial Cells.
Volume: 36
Issue: 6
Pages: 871-85
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Publication
15142971 | J:91055
First Author: Kelly OG
Year: 2004
Journal: Development
Title: The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice.
Volume: 131
Issue: 12
Pages: 2803-15
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Publication
25061805 | J:219004
First Author: Liedert A
Year: 2014
Journal: PLoS One
Title: Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice.
Volume: 9
Issue: 7
Pages: e103250
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Publication
19837032 | J:154020
First Author: Ye X
Year: 2009
Journal: Cell
Title: Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization.
Volume: 139
Issue: 2
Pages: 285-98
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Publication
28938444 | J:249434
First Author: Kim SP
Year: 2017
Journal: Endocrinology
Title: Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism.
Volume: 158
Issue: 11
Pages: 3805-3816
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Publication
17335347 | J:162734
First Author: Young JJ
Year: 2007
Journal: PLoS Pathog
Title: LRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin.
Volume: 3
Issue: 3
Pages: e27
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Publication
16973609 | J:115934
First Author: Lindvall C
Year: 2006
Journal: J Biol Chem
Title: The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis.
Volume: 281
Issue: 46
Pages: 35081-7
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Publication
15537447 | J:111359
First Author: Holmen SL
Year: 2004
Journal: J Bone Miner Res
Title: Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6.
Volume: 19
Issue: 12
Pages: 2033-40
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Publication
30668923 | J:288622
First Author: Liu J
Year: 2019
Journal: FASEB J
Title: Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.
Volume: 33
Issue: 4
Pages: 5615-5625
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Publication
33164872 | J:300822
 
First Author: Lim KE
Year: 2021
Journal: Bone
Title: Co-deletion of Lrp5 and Lrp6 in the skeleton severely diminishes bone gain from sclerostin antibody administration.
Volume: 143
Pages: 115708
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Publication
25375916 | J:227802
First Author: Kode A
Year: 2014
Journal: Nat Med
Title: Lrp5 regulation of bone mass and serotonin synthesis in the gut.
Volume: 20
Issue: 11
Pages: 1228-9
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Publication
26554834 | J:244410
First Author: Niziolek PJ
Year: 2015
Journal: PLoS One
Title: Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia.
Volume: 10
Issue: 11
Pages: e0140775
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Publication
22750014 | J:192405
First Author: Niziolek PJ
Year: 2012
Journal: Bone
Title: Mechanotransduction in bone tissue: The A214V and G171V mutations in Lrp5 enhance load-induced osteogenesis in a surface-selective manner.
Volume: 51
Issue: 3
Pages: 459-65
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Publication
19075000 | J:145745
First Author: Haÿ E
Year: 2009
Journal: Mol Cell Biol
Title: N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.
Volume: 29
Issue: 4
Pages: 953-64
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Publication
17002572 | J:128100
First Author: Ellies DL
Year: 2006
Journal: J Bone Miner Res
Title: Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity.
Volume: 21
Issue: 11
Pages: 1738-49
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Publication
22433869 | J:193007
First Author: Goel S
Year: 2012
Journal: J Biol Chem
Title: Both LRP5 and LRP6 receptors are required to respond to physiological Wnt ligands in mammary epithelial cells and fibroblasts.
Volume: 287
Issue: 20
Pages: 16454-66
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Publication
26681532 | J:251176
First Author: Galán-Díez M
Year: 2016
Journal: Biochim Biophys Acta
Title: Normal hematopoiesis and lack of β-catenin activation in osteoblasts of patients and mice harboring Lrp5 gain-of-function mutations.
Volume: 1863
Issue: 3
Pages: 490-498
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Publication
22567110 | J:187263
First Author: Javaheri B
Year: 2012
Journal: PLoS One
Title: Lrp5 is not required for the proliferative response of osteoblasts to strain but regulates proliferation and apoptosis in a cell autonomous manner.
Volume: 7
Issue: 5
Pages: e35726
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Publication
33831261 | J:325387
First Author: Leanza G
Year: 2021
Journal: J Bone Miner Res
Title: Gain-of-Function Lrp5 Mutation Improves Bone Mass and Strength and Delays Hyperglycemia in a Mouse Model of Insulin-Deficient Diabetes.
Volume: 36
Issue: 7
Pages: 1403-1415
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Publication
36552732 | J:334347
 
First Author: Gessler L
Year: 2022
Journal: Cells
Title: In Adult Skeletal Muscles, the Co-Receptors of Canonical Wnt Signaling, Lrp5 and Lrp6, Determine the Distribution and Size of Fiber Types, and Structure and Function of Neuromuscular Junctions.
Volume: 11
Issue: 24
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GXD Expression
GXD Expression
     
Probe: MGI:6177252
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190740
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Lrp5
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6177252
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190740
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Lrp5
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6177252
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190740
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Lrp5
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6177252
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190740
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Lrp5
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6177252
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190740
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Lrp5
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6177252
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190740
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Lrp5
Detected: false
Specimen Num: 6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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