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Search results 1 to 100 out of 3175 for Mapt

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Hits by Strain

Type Details Score
Gene
4137 | MAPT
Type: gene
Organism: human
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Gene
779920 | mapt
Type: gene
Organism: frog, western clawed
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Gene
281296 | MAPT
Type: gene
Organism: cattle
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Gene
key_37175 | MAPT
Type: gene
Organism: goat
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Gene
29477 | Mapt
Type: gene
Organism: rat
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Gene
450177 | MAPT
Type: gene
Organism: chimpanzee
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Gene
480488 | MAPT
Type: gene
Organism: dog, domestic
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Gene
426737 | MAPT
Type: gene
Organism: chicken
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Gene
574327 | MAPT
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:97180 | Mapt
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100128977 | MAPT-AS1
Type: gene
Organism: human
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Gene
100130148 | MAPT-IT1
Type: gene
Organism: human
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Publication
31789603 | J:355623
First Author: Zheng XY
Year: 2019
Journal: Aging (Albany NY)
Title: Kainic acid hyperphosphorylates tau via inflammasome activation in MAPT transgenic mice.
Volume: 11
Issue: 23
Pages: 10923-10938
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393446
Age: postnatal day 0
Image: 7 Mapt P0
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P0
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393446
Age: postnatal day 0
Image: 7 Mapt P0 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P0 orthogonal
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 12
Image: 7 Mapt P12
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P12
Detected: true
Specimen Num: 21
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 12
Image: 7 Mapt P12 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P12 orthogonal
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 64
Image: 7 Mapt P64
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P64
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
Probe: MGI:5308606
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393446
Age: postnatal day 64
Image: 7 Mapt P64 orthogonal
Note: Expression was detected in hair cells; a subset co-localized with Mapt.
Specimen Label: 7 Mapt P64 orthogonal
Detected: true
Specimen Num: 24
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Publication
30290707 | J:310931
First Author: Xu Y
Year: 2019
Journal: Autophagy
Title: The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau).
Volume: 15
Issue: 4
Pages: 583-598
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Publication
37047532 | J:334899
 
First Author: Andr?s-Benito P
Year: 2023
Journal: Int J Mol Sci
Title: Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse.
Volume: 24
Issue: 7
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Publication
31273083 | J:280392
First Author: Saito T
Year: 2019
Journal: J Biol Chem
Title: Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation.
Volume: 294
Issue: 34
Pages: 12754-12765
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Publication
30128323 | J:264801
First Author: Chen C
Year: 2018
Journal: Ann Clin Transl Neurol
Title: Mapt deletion fails to rescue premature lethality in two models of sodium channel epilepsy.
Volume: 5
Issue: 8
Pages: 982-987
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Publication
40220760 | J:365554
First Author: Morito T
Year: 2025
Journal: Cell Rep Methods
Title: Human MAPT knockin mouse models of frontotemporal dementia for the neurodegenerative research community.
Volume: 5
Issue: 4
Pages: 101024
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Publication
29282277 | J:329754
First Author: Caneus J
Year: 2018
Journal: Mol Biol Cell
Title: Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations.
Volume: 29
Issue: 5
Pages: 575-586
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Publication
36635241 | J:332555
 
First Author: Huang M
Year: 2022
Journal: eNeuro
Title: Increase in Tau Pathology in P290S Mapt Knock-In Mice Crossed with App (NL-G-F) Mice.
Volume: 9
Issue: 6
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Publication
41173863 | J:387096
First Author: Mueller RL
Year: 2025
Journal: Sci Rep
Title: Seeding Alzheimer's disease-associated tau pathology in MAPT knock-in primary neurons causes early axonopathy and synaptic dysfunction.
Volume: 15
Issue: 1
Pages: 38140
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Publication
29729423 | J:264741
 
First Author: Adalbert R
Year: 2018
Journal: Neurobiol Aging
Title: Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport.
Volume: 68
Pages: 68-75
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Publication
22796601 | J:191008
First Author: Filali M
Year: 2012
Journal: Behav Brain Res
Title: Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD).
Volume: 234
Issue: 2
Pages: 334-42
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190766
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Mapt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190766
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Mapt
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190766
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Mapt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190766
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Mapt
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190766
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Mapt
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190766
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Mapt
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6177589
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190766
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Mapt
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393311
Age: postnatal day 0
Image: 7 P0
Note: At P0, Mapt was barely detected in the utricle.
Specimen Label: 7 P0
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1729327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6393311
Age: postnatal day 0
Image: 7 P0 orthogonal
Note: At P0, Mapt was barely detected in the utricle.
Specimen Label: 7 P0 orthogonal
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 64
Image: 4D
Note: There was broad overlap of Mapt expression with the Type II hair cell marker, Calb2.
Specimen Label: 4D
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 12
Image: 7 P12
Note: At P12, Mapt was expressed in a significant number of Type II hair cells.
Specimen Label: 7 P12
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 12
Image: 7 P12 orthogonal
Note: At P12, Mapt was expressed in a significant number of Type II hair cells.
Specimen Label: 7 P12 orthogonal
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 64
Image: 7 P64
Note: At P64, Mapt was expressed in a significant number of Type II hair cells.
Specimen Label: 7 P64
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:6393274
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6393311
Age: postnatal day 64
Image: 7 P64 orthogonal
Note: At P64, Mapt was expressed in a significant number of Type II hair cells.
Specimen Label: 7 P64 orthogonal
Detected: true
Specimen Num: 9
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Publication
35332321 | J:368905
First Author: Kang SS
Year: 2022
Journal: Nat Struct Mol Biol
Title: Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation.
Volume: 29
Issue: 4
Pages: 292-305
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Publication
27210553 | J:240208
First Author: Schoch KM
Year: 2016
Journal: Neuron
Title: Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model.
Volume: 90
Issue: 5
Pages: 941-7
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Publication
25863528 | J:222621
First Author: Komuro Y
Year: 2015
Journal: Neurobiol Aging
Title: Human tau expression reduces adult neurogenesis in a mouse model of tauopathy.
Volume: 36
Issue: 6
Pages: 2034-42
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Publication
29614648 | J:369330
First Author: Masoud AM
Year: 2018
Journal: J Alzheimers Dis
Title: Altered microRNA, mRNA, and Protein Expression of Neurodegeneration-Related Biomarkers and Their Transcriptional and Epigenetic Modifiers in a Human Tau Transgenic Mouse Model in Response to Developmental Lead Exposure.
Volume: 63
Issue: 1
Pages: 273-282
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Publication
23459933 | J:198237
First Author: Avale ME
Year: 2013
Journal: Hum Mol Genet
Title: Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing.
Volume: 22
Issue: 13
Pages: 2603-11
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Publication
38310353 | J:369339
First Author: Facal CL
Year: 2024
Journal: Mol Ther
Title: Tau reduction with artificial microRNAs modulates neuronal physiology and improves tauopathy phenotypes in mice.
Volume: 32
Issue: 4
Pages: 1080-1095
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Publication
28859549 | J:285080
First Author: Kokiko-Cochran ON
Year: 2018
Journal: J Neurotrauma
Title: Traumatic Brain Injury in hTau Model Mice: Enhanced Acute Macrophage Response and Altered Long-Term Recovery.
Volume: 35
Issue: 1
Pages: 73-84
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Publication
35054902 | J:318850
 
First Author: Andr?s-Benito P
Year: 2022
Journal: Int J Mol Sci
Title: Host Tau Genotype Specifically Designs and Regulates Tau Seeding and Spreading and Host Tau Transformation Following Intrahippocampal Injection of Identical Tau AD Inoculum.
Volume: 23
Issue: 2
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Publication
36277399 | J:369337
 
First Author: Mu?iz JA
Year: 2022
Journal: Front Bioeng Biotechnol
Title: SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy.
Volume: 10
Pages: 951384
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Publication
36389767 | J:332109
 
First Author: Katsumoto A
Year: 2022
Journal: Front Immunol
Title: Triggering receptor expressed on myeloid cells 2 deficiency exacerbates injury-induced inflammation in a mouse model of tauopathy.
Volume: 13
Pages: 978423
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Publication
31065832 | J:294428
First Author: Sartori M
Year: 2019
Journal: Acta Neuropathol
Title: BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr(348) phosphorylation.
Volume: 138
Issue: 4
Pages: 631-652
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Publication
28367114 | J:284907
 
First Author: Maphis NM
Year: 2017
Journal: Front Mol Neurosci
Title: Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology.
Volume: 10
Pages: 69
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Publication
26311071 | J:229560
 
First Author: Xu L
Year: 2015
Journal: Exp Neurol
Title: Evidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury.
Volume: 273
Pages: 168-76
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Publication
38192302 | J:348759
 
First Author: Vemula P
Year: 2023
Journal: Front Mol Neurosci
Title: Evaluating the efficacy of purchased antisense oligonucleotides to reduce mouse and human tau in vivo.
Volume: 16
Pages: 1320182
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Publication
37842124 | J:347846
 
First Author: Benskey MJ
Year: 2023
Journal: Front Aging Neurosci
Title: Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse.
Volume: 15
Pages: 1265151
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Publication
35082119 | J:353267
First Author: Gerson JE
Year: 2022
Journal: J Neurosci
Title: Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy.
Volume: 42
Issue: 9
Pages: 1845-1863
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Publication
31223056 | J:306853
First Author: Feng Q
Year: 2020
Journal: Autophagy
Title: MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.
Volume: 16
Issue: 4
Pages: 641-658
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Publication
30120733 | J:285073
First Author: Comerota MM
Year: 2019
Journal: Mol Neurobiol
Title: Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies.
Volume: 56
Issue: 5
Pages: 3341-3355
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Publication
38131009 | J:343622
 
First Author: Wang Y
Year: 2023
Journal: Front Aging Neurosci
Title: A tau fragment links depressive-like behaviors and cognitive declines in Alzheimer's disease mouse models through attenuating mitochondrial function.
Volume: 15
Pages: 1293164
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Publication
33859747 | J:348495
First Author: Wang W
Year: 2021
Journal: Theranostics
Title: A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models.
Volume: 11
Issue: 11
Pages: 5279-5295
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Publication
36114722 | J:368782
First Author: Li L
Year: 2022
Journal: CNS Neurosci Ther
Title: Tau antibody 77G7 targeting microtubule binding domain suppresses proteopathic tau to seed tau aggregation.
Volume: 28
Issue: 12
Pages: 2245-2259
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Publication
40054691 | J:368906
First Author: Yao J
Year: 2025
Journal: J Biol Chem
Title: Human tau promotes Warburg effect-like glycolytic metabolism under acute hyperglycemia conditions.
Volume: 301
Issue: 4
Pages: 108376
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Publication
31765727 | J:310719
 
First Author: Cheng H
Year: 2020
Journal: Neurobiol Dis
Title: Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice.
Volume: 134
Pages: 104683
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Publication
39719507 | J:362504
First Author: Watamura N
Year: 2025
Journal: Nat Neurosci
Title: In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds.
Volume: 28
Issue: 2
Pages: 293-307
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Publication
32778161 | J:353258
First Author: Farmer KM
Year: 2020
Journal: Acta Neuropathol Commun
Title: P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer's disease.
Volume: 8
Issue: 1
Pages: 132
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Publication
33482356 | J:307763
 
First Author: Marquez A
Year: 2021
Journal: Neurobiol Dis
Title: Tau associated peripheral and central neurodegeneration: Identification of an early imaging marker for tauopathy.
Volume: 151
Pages: 105273
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Publication
19041304 | J:174270
First Author: Levine S
Year: 2009
Journal: Exp Mol Pathol
Title: Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.
Volume: 86
Issue: 1
Pages: 18-22
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Publication
30915013 | J:311096
 
First Author: Rubenstein R
Year: 2019
Journal: Front Neurol
Title: Novel Mouse Tauopathy Model for Repetitive Mild Traumatic Brain Injury: Evaluation of Long-Term Effects on Cognition and Biomarker Levels After Therapeutic Inhibition of Tau Phosphorylation.
Volume: 10
Pages: 124
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Publication
41487117 | J:389980
 
First Author: Moseley MC
Year: 2025
Journal: Front Syst Neurosci
Title: Differential effects of tau expression on seizures and epileptogenesis in a mouse model of temporal lobe epilepsy.
Volume: 19
Pages: 1693339
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Publication
27814296 | J:369329
First Author: Dengler-Crish CM
Year: 2017
Journal: J Alzheimers Dis
Title: Early Evidence of Low Bone Density and Decreased Serotonergic Synthesis in the Dorsal Raphe of a?Tauopathy Model of Alzheimer's Disease.
Volume: 55
Issue: 4
Pages: 1605-1619
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Publication
34029610 | J:353257
 
First Author: Cloyd RA
Year: 2021
Journal: Exp Neurol
Title: Effects of altered tau expression on dentate granule cell excitability in mice.
Volume: 343
Pages: 113766
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Publication
29669277 | J:271116
First Author: Esp?ndola SL
Year: 2018
Journal: Cell Rep
Title: Modulation of Tau Isoforms Imbalance Precludes Tau Pathology and Cognitive Decline in a Mouse Model of Tauopathy.
Volume: 23
Issue: 3
Pages: 709-715
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Publication
30890929 | J:310583
 
First Author: Miao J
Year: 2019
Journal: Front Aging Neurosci
Title: Pathological Tau From Alzheimer's Brain Induces Site-Specific Hyperphosphorylation and SDS- and Reducing Agent-Resistant Aggregation of Tau in vivo.
Volume: 11
Pages: 34
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Publication
36555581 | J:347451
 
First Author: Ferrer I
Year: 2022
Journal: Int J Mol Sci
Title: Common and Specific Marks of Different Tau Strains Following Intra-Hippocampal Injection of AD, PiD, and GGT Inoculum in hTau Transgenic Mice.
Volume: 23
Issue: 24
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Publication
33768561 | J:369334
First Author: Bretland KA
Year: 2021
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