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Search results 1 to 94 out of 94 for Mcub

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Type Details Score
Gene
55013 | MCUB
Type: gene
Organism: human
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Gene
698670 | MCUB
Type: gene
Organism: macaque, rhesus
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Gene
100145024 | mcub
Type: gene
Organism: frog, western clawed
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Gene
295462 | Mcub
Type: gene
Organism: rat
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Gene
478513 | MCUB
Type: gene
Organism: dog, domestic
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Gene
461432 | MCUB
Type: gene
Organism: chimpanzee
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Gene
504728 | MCUB
Type: gene
Organism: cattle
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Gene
422698 | MCUB
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:1914065 | Mcub
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32299299 | J:293201
First Author: Huo J
Year: 2020
Journal: Circ Res
Title: MCUb Induction Protects the Heart From Postischemic Remodeling.
Volume: 127
Issue: 3
Pages: 379-390
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Publication
34726954 | J:338466
First Author: Feno S
Year: 2021
Journal: Sci Signal
Title: The dominant-negative mitochondrial calcium uniporter subunit MCUb drives macrophage polarization during skeletal muscle regeneration.
Volume: 14
Issue: 707
Pages: eabf3838
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Publication
37976157 | J:344737
First Author: Huo J
Year: 2023
Journal: Cell Rep
Title: MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle.
Volume: 42
Issue: 11
Pages: 113465
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Publication
31533452 | J:298046
First Author: Lambert JP
Year: 2019
Journal: Circulation
Title: MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress.
Volume: 140
Issue: 21
Pages: 1720-1733
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Publication
23900286 | J:201635
First Author: Raffaello A
Year: 2013
Journal: EMBO J
Title: The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit.
Volume: 32
Issue: 17
Pages: 2362-76
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Publication
37061131 | J:338590
First Author: Ghatge M
Year: 2023
Journal: J Thromb Haemost
Title: Mitochondrial calcium uniporter b deletion inhibits platelet function and reduces susceptibility to arterial thrombosis.
Volume: 21
Issue: 8
Pages: 2163-2174
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Protein Coding Gene
MGP_CAROLIEiJ_G0025631 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027878 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027836 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027849 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027578 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914065 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028293 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027662 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027804 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027693 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028350 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026759 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027080 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026584 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
38514795 | J:346444
First Author: Bround MJ
Year: 2024
Journal: Sci Rep
Title: MCU-independent Ca(2+) uptake mediates mitochondrial Ca(2+) overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy.
Volume: 14
Issue: 1
Pages: 6751
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Publication
26828201 | J:240084
First Author: Márkus NM
Year: 2016
Journal: PLoS One
Title: Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling.
Volume: 11
Issue: 2
Pages: e0148164
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Publication
35302860 | J:322729
First Author: Singh R
Year: 2022
Journal: Sci Adv
Title: Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients.
Volume: 8
Issue: 11
Pages: eabj4716
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Publication
19906978 | J:154739
First Author: Quina LA
Year: 2009
Journal: J Neurosci
Title: Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.
Volume: 29
Issue: 45
Pages: 14309-22
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Protein
D6RIL8
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: false
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Protein
F6SD17
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
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Allele
Mcub<tm1d(KOMP)Mbp> | MGI:7513946
Name: mitochondrial calcium uniporter dominant negative beta subunit; targeted mutation 1d, Mouse Biology Program, UC Davis
Allele Type: Targeted
Attribute String: Null/knockout
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Protein
Q810S1
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
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Allele
Tg(Myh6/tetO-Mcub)#Jmol | MGI:6452410
Name: transgene insertion, Jeffery Molkentin
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence
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Protein Coding Gene
MGI:88068 | Areg
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR039055 | MCU_fam
Type: Family
Description: This entry represents the MCU family, whose members include MCU and MCUb from mammals and MCU1-6 from Arabidopsis. MCU is a mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria [, , ]. MCUb negatively regulates the activity of MCU [].
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Publication
12573256 | J:82006
First Author: Johnson KR
Year: 2003
Journal: Genomics
Title: Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5.
Volume: 81
Issue: 1
Pages: 6-14
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Publication
25395669 | J:217394
First Author: Siggs OM
Year: 2014
Journal: Biol Open
Title: Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.
Volume: 3
Issue: 12
Pages: 1151-7
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Publication
21685886 | J:174848
First Author: Baughman JM
Year: 2011
Journal: Nature
Title: Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Volume: 476
Issue: 7360
Pages: 341-5
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Publication
21685888 | J:174847
First Author: De Stefani D
Year: 2011
Journal: Nature
Title: A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.
Volume: 476
Issue: 7360
Pages: 336-40
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Protein
Q3UMR5
Organism: Mus musculus/domesticus
Length: 350  
Fragment?: false
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Publication
23101630 | -
First Author: Mallilankaraman K
Year: 2012
Journal: Cell
Title: MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Volume: 151
Issue: 3
Pages: 630-44
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Allele
Areg<Mcub> | MGI:2653137
Name: amphiregulin; modifier of curly bare
Allele Type: Spontaneous
Attribute String: Null/knockout
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Publication
37903947 | J:342557
First Author: Raugh A
Year: 2023
Journal: Sci Rep
Title: The amphiregulin/EGFR axis has limited contribution in controlling autoimmune diabetes.
Volume: 13
Issue: 1
Pages: 18653
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Genotype
Genotype
Symbol: Areg/Areg
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:2174033 | B6.Cg-Areg<Mcub> Rhbdf2<cub>/J
Attribute String: congenic, mutant strain
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Publication
29116018 | J:250259
First Author: Hosur V
Year: 2017
Journal: BMC Res Notes
Title: Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.
Volume: 10
Issue: 1
Pages: 573
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Genotype
Genotype
Symbol: Rhbdf2/Rhbdf2 Areg/Areg<+>
Background: involves: C57BL/6J * STOCK a us/J * V/LeJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Areg/Areg Rhbdf2/Rhbdf2
Background: involves: C57BL/6J * V/LeJ
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Areg/Areg Rhbdf2/Rhbdf2
Background: involves: C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
28655741 | J:244160
First Author: Hosur V
Year: 2017
Journal: Biol Open
Title: Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.
Volume: 6
Issue: 8
Pages: 1174-1179
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Publication
36948287 | J:345305
 
First Author: Xu H
Year: 2023
Journal: Metabolism
Title: Syntaxin17 contributes to obesity cardiomyopathy through promoting mitochondrial Ca(2+) overload in a Parkin-MCUb-dependent manner.
Volume: 143
Pages: 155551
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Publication
24825892 | J:211269
First Author: Hosur V
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
Volume: 111
Issue: 21
Pages: E2200-9
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Publication
30022999 | J:275895
 
First Author: Hosur V
Year: 2018
Journal: Front Genet
Title: RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?
Volume: 9
Pages: 233
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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