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Search results 1 to 100 out of 269 for Mettl3

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Type Details Score
Gene
56339 | METTL3
Type: gene
Organism: human
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Gene
452765 | METTL3
Type: gene
Organism: chimpanzee
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Gene
475404 | METTL3
Type: gene
Organism: dog, domestic
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Gene
540339 | METTL3
Type: gene
Organism: cattle
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Gene
100004398 | mettl3
Type: gene
Organism: zebrafish
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Gene
706852 | METTL3
Type: gene
Organism: macaque, rhesus
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Gene
549173 | mettl3
Type: gene
Organism: frog, western clawed
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Gene
107050363 | METTL3
Type: gene
Organism: chicken
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Gene
361035 | Mettl3
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1927165 | Mettl3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
34893641 | J:341145
First Author: Li X
Year: 2021
Journal: Nat Commun
Title: The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression.
Volume: 12
Issue: 1
Pages: 7213
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Publication
33417895 | J:305101
 
First Author: Li X
Year: 2021
Journal: Metabolism
Title: METTL3 is required for maintaining β-cell function.
Volume: 116
Pages: 154702
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Publication
32245957 | J:287107
First Author: Wang Y
Year: 2020
Journal: Nat Commun
Title: METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.
Volume: 11
Issue: 1
Pages: 1648
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Publication
36693099 | J:338573
First Author: Zheng ZH
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: METTL3 is essential for normal progesterone signaling during embryo implantation via m(6)A-mediated translation control of progesterone receptor.
Volume: 120
Issue: 5
Pages: e2214684120
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Publication
35512709 | J:326534
First Author: Raj N
Year: 2022
Journal: Mol Cell
Title: The Mettl3 epitranscriptomic writer amplifies p53 stress responses.
Volume: 82
Issue: 13
Pages: 2370-2384.e10
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Publication
29186125 | J:271419
First Author: Barbieri I
Year: 2017
Journal: Nature
Title: Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control.
Volume: 552
Issue: 7683
Pages: 126-131
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Publication
30586742 | J:280000
First Author: Dorn LE
Year: 2019
Journal: Circulation
Title: The N6-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy.
Volume: 139
Issue: 4
Pages: 533-545
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Publication
37379215 | J:338536
First Author: Wei T
Year: 2023
Journal: Cell Rep
Title: Loss of Mettl3 enhances liver tumorigenesis by inducing hepatocyte dedifferentiation and hyperproliferation.
Volume: 42
Issue: 7
Pages: 112704
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Publication
37224383 | J:341329
First Author: Xie R
Year: 2023
Journal: Diabetes
Title: Activation of METTL3 Promotes White Adipose Tissue Beiging and Combats Obesity.
Volume: 72
Issue: 8
Pages: 1083-1094
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Publication
35013323 | J:329806
First Author: Petrosino JM
Year: 2022
Journal: Nat Commun
Title: The m6A methyltransferase METTL3 regulates muscle maintenance and growth in mice.
Volume: 13
Issue: 1
Pages: 168
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Publication
36881554 | J:346277
First Author: Yin H
Year: 2023
Journal: PLoS Biol
Title: Loss of the m6A methyltransferase METTL3 in monocyte-derived macrophages ameliorates Alzheimer's disease pathology in mice.
Volume: 21
Issue: 3
Pages: e3002017
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Publication
31201338 | J:297128
First Author: Kwon J
Year: 2019
Journal: Sci Rep
Title: Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development.
Volume: 9
Issue: 1
Pages: 8640
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Publication
34599880 | J:318717
First Author: Barajas JM
Year: 2022
Journal: Am J Pathol
Title: METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
Volume: 192
Issue: 1
Pages: 56-71
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Publication
34428587 | J:341328
 
First Author: Gong R
Year: 2021
Journal: Pharmacol Res
Title: Loss of m(6)A methyltransferase METTL3 promotes heart regeneration and repair after myocardial injury.
Volume: 174
Pages: 105845
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Publication
32121289 | J:297755
 
First Author: Li D
Year: 2020
Journal: Int J Mol Sci
Title: METTL3 Modulates Osteoclast Differentiation and Function by Controlling RNA Stability and Nuclear Export.
Volume: 21
Issue: 5
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Publication
31186141 | J:291567
First Author: Liu Q
Year: 2019
Journal: Biochem Biophys Res Commun
Title: METTL3 promotes experimental osteoarthritis development by regulating inflammatory response and apoptosis in chondrocyte.
Volume: 516
Issue: 1
Pages: 22-27
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Publication
31405565 | J:290815
First Author: Xie W
Year: 2019
Journal: Biochem Biophys Res Commun
Title: METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism.
Volume: 518
Issue: 1
Pages: 120-126
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Publication
35639638 | J:334503
First Author: Zhu Y
Year: 2022
Journal: Biol Reprod
Title: Mettl3 downregulation in germinal vesicle oocytes inhibits mRNA decay and the first polar body extrusion during maturation†.
Volume: 107
Issue: 3
Pages: 765-778
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Publication
33217448 | J:309644
First Author: Chen H
Year: 2021
Journal: Gastroenterology
Title: RNA N6-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m6A-GLUT1-mTORC1 Axis and Is a Therapeutic Target.
Volume: 160
Issue: 4
Pages: 1284-1300.e16
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Publication
28809392 | J:250433
First Author: Xu K
Year: 2017
Journal: Cell Res
Title: Mettl3-mediated m6A regulates spermatogonial differentiation and meiosis initiation.
Volume: 27
Issue: 9
Pages: 1100-1114
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Publication
- | J:337787
First Author: Wang Y
Year: 2022
Journal: Life Metabolism
Title: WTAP regulates postnatal development of brown adipose tissue by stabilizing METTL3 in mice.
Volume: 1
Issue: 3
Pages: 270-284
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Publication
24209618 | J:203416
First Author: Fustin JM
Year: 2013
Journal: Cell
Title: RNA-methylation-dependent RNA processing controls the speed of the circadian clock.
Volume: 155
Issue: 4
Pages: 793-806
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Publication
28637692 | J:248553
First Author: Ke S
Year: 2017
Journal: Genes Dev
Title: m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover.
Volume: 31
Issue: 10
Pages: 990-1006
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Publication
34262022 | J:314515
First Author: Du K
Year: 2021
Journal: Cell Death Dis
Title: Distinct roles of Fto and Mettl3 in controlling development of the cerebral cortex through transcriptional and translational regulations.
Volume: 12
Issue: 7
Pages: 700
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Publication
36265285 | J:334214
 
First Author: Zheng L
Year: 2022
Journal: Biochem Biophys Res Commun
Title: RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.
Volume: 635
Pages: 120-127
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Publication
28792938 | J:249262
First Author: Li HB
Year: 2017
Journal: Nature
Title: m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.
Volume: 548
Issue: 7667
Pages: 338-342
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Publication
25569111 | J:219587
First Author: Geula S
Year: 2015
Journal: Science
Title: Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.
Volume: 347
Issue: 6225
Pages: 1002-6
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Publication
9409616 | J:70548
First Author: Bokar JA
Year: 1997
Journal: RNA
Title: Purification and cDNA cloning of the AdoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase.
Volume: 3
Issue: 11
Pages: 1233-47
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Publication
25456834 | J:219614
First Author: Batista PJ
Year: 2014
Journal: Cell Stem Cell
Title: m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells.
Volume: 15
Issue: 6
Pages: 707-19
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Publication
11389549 | J:69146
First Author: Hwang SY
Year: 2001
Journal: Mol Reprod Dev
Title: Expression of genes involved in mammalian meiosis during the transition from egg to embryo.
Volume: 59
Issue: 2
Pages: 144-58
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Publication
24394384 | J:207885
First Author: Wang Y
Year: 2014
Journal: Nat Cell Biol
Title: N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells.
Volume: 16
Issue: 2
Pages: 191-8
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Publication
28914256 | J:250428
First Author: Lin Z
Year: 2017
Journal: Cell Res
Title: Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis.
Volume: 27
Issue: 10
Pages: 1216-1230
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Publication
28965759 | J:247703
First Author: Yoon KJ
Year: 2017
Journal: Cell
Title: Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation.
Volume: 171
Issue: 4
Pages: 877-889.e17
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Publication
35417191 | J:326758
First Author: Wang JN
Year: 2022
Journal: Sci Transl Med
Title: Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms.
Volume: 14
Issue: 640
Pages: eabk2709
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Publication
32943573 | J:299108
First Author: Lasman L
Year: 2020
Journal: Genes Dev
Title: Context-dependent functional compensation between Ythdf m6A reader proteins.
Volume: 34
Issue: 19-20
Pages: 1373-1391
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Publication
29547716 | J:261823
First Author: Wen J
Year: 2018
Journal: Mol Cell
Title: Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Volume: 69
Issue: 6
Pages: 1028-1038.e6
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Publication
33637761 | J:304853
First Author: Yao Y
Year: 2021
Journal: Nat Commun
Title: METTL3-dependent m6A modification programs T follicular helper cell differentiation.
Volume: 12
Issue: 1
Pages: 1333
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Publication
34689175 | J:313434
First Author: Mu H
Year: 2021
Journal: Cell Death Dis
Title: METTL3-mediated mRNA N6-methyladenosine is required for oocyte and follicle development in mice.
Volume: 12
Issue: 11
Pages: 989
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Publication
31015515 | J:275560
First Author: Wang H
Year: 2019
Journal: Nat Commun
Title: Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation.
Volume: 10
Issue: 1
Pages: 1898
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Publication
34535671 | J:312777
First Author: Song H
Year: 2021
Journal: Nat Commun
Title: METTL3-mediated m6A RNA methylation promotes the anti-tumour immunity of natural killer cells.
Volume: 12
Issue: 1
Pages: 5522
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Publication
31412241 | J:280698
First Author: Cheng Y
Year: 2019
Journal: Cell Rep
Title: m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.
Volume: 28
Issue: 7
Pages: 1703-1716.e6
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Publication
37696947 | J:341095
First Author: Collignon E
Year: 2023
Journal: Nat Cell Biol
Title: m(6)A RNA methylation orchestrates transcriptional dormancy during paused pluripotency.
Volume: 25
Issue: 9
Pages: 1279-1289
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Publication
30297870 | J:294441
First Author: Zhang Z
Year: 2018
Journal: Cell Res
Title: METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation.
Volume: 28
Issue: 11
Pages: 1050-1061
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Publication
35320754 | J:325472
First Author: Xiong J
Year: 2022
Journal: Mol Cell
Title: Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells.
Volume: 82
Issue: 9
Pages: 1660-1677.e10
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Publication
30429466 | J:268410
First Author: Wu Y
Year: 2018
Journal: Nat Commun
Title: Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis.
Volume: 9
Issue: 1
Pages: 4772
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Publication
33654093 | J:304891
First Author: Yin H
Year: 2021
Journal: Nat Commun
Title: RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming.
Volume: 12
Issue: 1
Pages: 1394
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Publication
32497523 | J:305837
First Author: Gao Y
Year: 2020
Journal: Immunity
Title: m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development.
Volume: 52
Issue: 6
Pages: 1007-1021.e8
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Publication
37335109 | J:338111
First Author: Dai G
Year: 2023
Journal: Aging (Albany NY)
Title: Mettl3-mediated m(6)A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression.
Volume: 15
Issue: 12
Pages: 5550-5568
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Publication
37267102 | J:338145
First Author: You M
Year: 2023
Journal: Cell Rep
Title: Mettl3-m(6)A-Creb1 forms an intrinsic regulatory axis in maintaining iNKT cell pool and functional differentiation.
Volume: 42
Issue: 6
Pages: 112584
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Publication
34402854 | J:338279
 
First Author: Grenov AC
Year: 2021
Journal: J Exp Med
Title: The germinal center reaction depends on RNA methylation and divergent functions of specific methyl readers.
Volume: 218
Issue: 10
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Publication
36396934 | J:334205
First Author: Zhang X
Year: 2022
Journal: Nat Commun
Title: N6-methyladenosine modification governs liver glycogenesis by stabilizing the glycogen synthase 2 mRNA.
Volume: 13
Issue: 1
Pages: 7038
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Publication
33910903 | J:314928
 
First Author: Tong J
Year: 2021
Journal: Sci Adv
Title: Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation.
Volume: 7
Issue: 18
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Publication
34758326 | J:326975
First Author: Qin Y
Year: 2021
Journal: Cell Rep
Title: m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity.
Volume: 37
Issue: 6
Pages: 109968
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Publication
33020597 | J:310115
First Author: Gao XQ
Year: 2020
Journal: Nat Cell Biol
Title: The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N6-methyladenosine methylation of Parp10 mRNA.
Volume: 22
Issue: 11
Pages: 1319-1331
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Publication
33852874 | J:307671
First Author: Ramalingam H
Year: 2021
Journal: Cell Metab
Title: A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease.
Volume: 33
Issue: 6
Pages: 1234-1247.e7
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Publication
35172162 | J:320434
First Author: Chen J
Year: 2022
Journal: Cell Rep
Title: TBK1-METTL3 axis facilitates antiviral immunity.
Volume: 38
Issue: 7
Pages: 110373
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Publication
31061465 | J:278901
First Author: Lee H
Year: 2019
Journal: Nat Cell Biol
Title: Stage-specific requirement for Mettl3-dependent m6A mRNA methylation during haematopoietic stem cell differentiation.
Volume: 21
Issue: 6
Pages: 700-709
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Publication
30048615 | J:264833
First Author: Engel M
Year: 2018
Journal: Neuron
Title: The Role of m6A/m-RNA Methylation in Stress Response Regulation.
Volume: 99
Issue: 2
Pages: 389-403.e9
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Publication
34450044 | J:315843
First Author: Nair L
Year: 2021
Journal: Mol Cell
Title: Mechanism of noncoding RNA-associated N6-methyladenosine recognition by an RNA processing complex during IgH DNA recombination.
Volume: 81
Issue: 19
Pages: 3949-3964.e7
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Publication
36920907 | J:334735
First Author: Luo S
Year: 2023
Journal: Cell Rep
Title: METTL3-mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling.
Volume: 42
Issue: 3
Pages: 112259
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Publication
37270544 | J:336598
First Author: Wan S
Year: 2023
Journal: Cell Death Dis
Title: METTL3-dependent m(6)A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling.
Volume: 14
Issue: 6
Pages: 349
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Publication
35098923 | J:343961
   
First Author: Wang A
Year: 2022
Journal: Elife
Title: m6A modifications regulate intestinal immunity and rotavirus infection.
Volume: 11
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Publication
34987645 | J:333644
First Author: Suo L
Year: 2022
Journal: Theranostics
Title: METTL3-mediated N(6)-methyladenosine modification governs pericyte dysfunction during diabetes-induced retinal vascular complication.
Volume: 12
Issue: 1
Pages: 277-289
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Publication
34660602 | J:312373
 
First Author: Xie SJ
Year: 2021
Journal: Front Cell Dev Biol
Title: Dynamic m6A mRNA Methylation Reveals the Role of METTL3/14-m6A-MNK2-ERK Signaling Axis in Skeletal Muscle Differentiation and Regeneration.
Volume: 9
Pages: 744171
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Publication
36920524 | J:341144
First Author: Li X
Year: 2023
Journal: Diabetologia
Title: Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice.
Volume: 66
Issue: 6
Pages: 1084-1096
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Publication
36482889 | J:331893
 
First Author: Yang J
Year: 2022
Journal: Front Genet
Title: Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses.
Volume: 13
Pages: 974357
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Publication
29866655 | J:265275
 
First Author: Kobayashi M
Year: 2018
Journal: Mol Cell Biol
Title: The RNA Methyltransferase Complex of WTAP, METTL3, and METTL14 Regulates Mitotic Clonal Expansion in Adipogenesis.
Volume: 38
Issue: 16
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Publication
29507755 | J:319950
 
First Author: Yue Y
Year: 2018
Journal: Cell Discov
Title: VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation.
Volume: 4
Pages: 10
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Publication
29879109 | J:263687
First Author: Wang CX
Year: 2018
Journal: PLoS Biol
Title: METTL3-mediated m6A modification is required for cerebellar development.
Volume: 16
Issue: 6
Pages: e2004880
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Protein Coding Gene
MGP_CAROLIEiJ_G0019240 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021253 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021257 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021037 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1927165 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021696 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020556 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021004 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021200 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021131 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020305 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030261 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020132 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6867067
Assay Type: Western blot
Annotation Date: 2022-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3263720
Stage: TS20
Assay Id: MGI:6867076
Age: embryonic day 12.5
Image: 1
Specimen Label: E12.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6867067
Assay Type: Western blot
Annotation Date: 2022-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3604823
Stage: TS23
Assay Id: MGI:6867076
Age: embryonic day 15.5
Image: 1
Specimen Label: E15.5
Detected: true
Specimen Num: 2
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