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Search results 1 to 95 out of 95 for Muc4

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
4585 | MUC4
Type: gene
Organism: human
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Gene
460952 | MUC4
Type: gene
Organism: chimpanzee
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Gene
786701 | MUC4
Type: gene
Organism: cattle
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Gene
713146 | MUC4
Type: gene
Organism: macaque, rhesus
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Gene
101752124 | MUC4
Type: gene
Organism: chicken
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Gene
100485162 | muc4
Type: gene
Organism: frog, western clawed
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Gene
303887 | Muc4
Type: gene
Organism: rat
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Gene
488024 | MUC4
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2153525 | Muc4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:72744
   
First Author: Bartman AE
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mucin Muc4 mRNA, partial cds
Pages: AF218265
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Publication
36624189 | J:333837
First Author: Bhatia R
Year: 2023
Journal: Oncogene
Title: Muc4 loss mitigates epidermal growth factor receptor activity essential for PDAC tumorigenesis.
Volume: 42
Issue: 10
Pages: 759-770
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Publication
26364605 | J:234205
First Author: Das S
Year: 2016
Journal: Oncogene
Title: Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer.
Volume: 35
Issue: 20
Pages: 2645-54
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Publication
25174601 | J:320856
First Author: Miyahara N
Year: 2014
Journal: Oncol Rep
Title: Interaction of Muc4 and ErbB2 in a transgenic mouse model of gallbladder carcinoma: potential pathobiological implications.
Volume: 32
Issue: 5
Pages: 1796-802
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Publication
28892049 | J:254258
First Author: Rowson-Hodel AR
Year: 2018
Journal: Oncogene
Title: Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer.
Volume: 37
Issue: 2
Pages: 197-207
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Publication
26477488 | J:231383
First Author: Vasseur R
Year: 2015
Journal: Biochim Biophys Acta
Title: The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways.
Volume: 1849
Issue: 12
Pages: 1375-84
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Publication
- | J:287566
     
First Author: Plante JA
Year: 2020
Journal: bioRxiv
Title: Mucin 4 Protects Female Mice from Coronavirus Pathogenesis.
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Publication
12084055 | J:77741
First Author: Desseyn JL
Year: 2002
Journal: Eur J Biochem
Title: Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4.
Volume: 269
Issue: 13
Pages: 3150-9
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Publication
24240113 | J:317293
First Author: Kaur S
Year: 2014
Journal: Clin Cancer Res
Title: MUC4-mediated regulation of acute phase protein lipocalin 2 through HER2/AKT/NF-κB signaling in pancreatic cancer.
Volume: 20
Issue: 3
Pages: 688-700
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Protein Coding Gene
MGI_C57BL6J_2153525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
     
Probe: MGI:6368574
Assay Type: RT-PCR
Annotation Date: 2019-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893926
Stage: TS26
Assay Id: MGI:6368578
Age: embryonic day 18.5
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6368574
Assay Type: RT-PCR
Annotation Date: 2019-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893926
Stage: TS26
Assay Id: MGI:6368578
Age: embryonic day 18.5
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6368574
Assay Type: RT-PCR
Annotation Date: 2019-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893926
Stage: TS26
Assay Id: MGI:6368578
Age: embryonic day 18.5
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6368574
Assay Type: RT-PCR
Annotation Date: 2019-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893926
Stage: TS26
Assay Id: MGI:6368578
Age: embryonic day 18.5
Specimen Label: 5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6368574
Assay Type: RT-PCR
Annotation Date: 2019-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893926
Stage: TS26
Assay Id: MGI:6368578
Age: embryonic day 18.5
Specimen Label: 6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6368574
Assay Type: RT-PCR
Annotation Date: 2019-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1893926
Stage: TS26
Assay Id: MGI:6368578
Age: embryonic day 18.5
Specimen Label: 7
Detected: true
Specimen Num: 7
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Publication
19158956 | J:152513
 
First Author: Wang IJ
Year: 2009
Journal: Mol Vis
Title: Alteration of ocular surface mucins in MUC5AC-DTA transgenic mice.
Volume: 15
Pages: 108-19
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Publication
26036346 | J:233926
First Author: Tréhoux S
Year: 2015
Journal: Biochim Biophys Acta
Title: Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells.
Volume: 1853
Issue: 10 Pt A
Pages: 2392-403
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Publication
35879412 | J:331758
First Author: Biering SB
Year: 2022
Journal: Nat Genet
Title: Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.
Volume: 54
Issue: 8
Pages: 1078-1089
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Publication
12107190 | J:79116
First Author: Lee CG
Year: 2002
Journal: J Biol Chem
Title: Transgenic overexpression of interleukin (IL)-10 in the lung causes mucus metaplasia, tissue inflammation, and airway remodeling via IL-13-dependent and -independent pathways.
Volume: 277
Issue: 38
Pages: 35466-74
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Protein
Q9QXG1
Organism: Mus musculus/domesticus
Length: 1403  
Fragment?: true
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Publication
21703447 | J:173368
First Author: Wang X
Year: 2011
Journal: Cell
Title: Residual embryonic cells as precursors of a Barrett's-like metaplasia.
Volume: 145
Issue: 7
Pages: 1023-35
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Publication
28898113 | J:257406
First Author: Metwalli KA
Year: 2018
Journal: J Dent Res
Title: Interferon Regulatory Factor 6 Is Necessary for Salivary Glands and Pancreas Development.
Volume: 97
Issue: 2
Pages: 226-236
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Publication
22766025 | J:190582
First Author: Bondow BJ
Year: 2012
Journal: Dev Biol
Title: E-cadherin is required for intestinal morphogenesis in the mouse.
Volume: 371
Issue: 1
Pages: 1-12
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Publication
16618389 | J:124920
First Author: Garrison WD
Year: 2006
Journal: Gastroenterology
Title: Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon.
Volume: 130
Issue: 4
Pages: 1207-20
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Publication
29997285 | J:267911
 
First Author: Timmermans S
Year: 2018
Journal: JCI Insight
Title: Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J.
Volume: 3
Issue: 13
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Publication
26411367 | J:234310
First Author: Kuo TL
Year: 2016
Journal: Oncogene
Title: APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice.
Volume: 35
Issue: 17
Pages: 2223-34
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Publication
24029230 | J:202604
First Author: Nagamachi A
Year: 2013
Journal: Cancer Cell
Title: Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Volume: 24
Issue: 3
Pages: 305-17
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Publication
28071719 | J:265607
 
First Author: Naba A
Year: 2017
Journal: Sci Rep
Title: Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.
Volume: 7
Pages: 40495
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
20062084 | J:160391
First Author: Mejías-Luque R
Year: 2010
Journal: Oncogene
Title: Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors.
Volume: 29
Issue: 12
Pages: 1753-62
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Publication
24608432 | J:218625
First Author: Lahdaoui F
Year: 2015
Journal: Oncogene
Title: miR-219-1-3p is a negative regulator of the mucin MUC4 expression and is a tumor suppressor in pancreatic cancer.
Volume: 34
Issue: 6
Pages: 780-8
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Publication
10880365 | J:63677
First Author: Price-Schiavi SA
Year: 2000
Journal: Biochem J
Title: Cloning and characterization of the 5' flanking region of the sialomucin complex/rat Muc4 gene: promoter activity in cultured cells.
Volume: 349
Issue: Pt 2
Pages: 641-9
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Publication
16500040 | -
 
First Author: Duraisamy S
Year: 2006
Journal: Gene
Title: Distinct evolution of the human carcinoma-associated transmembrane mucins, MUC1, MUC4 AND MUC16.
Volume: 373
Pages: 28-34
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Allele
Muc4<PWK/PhJ> | MGI:6423091
 
Name: mucin 4; PWK/PhJ
Attribute String: Hypomorph
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Genotype
Genotype
Symbol: Muc4/Muc4
Background: PWK/PhJ
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:2160654 | PWK/PhJ
Attribute String: wild-derived, inbred strain
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Protein Domain
IPR005533 | AMOP_dom
Type: Domain
Description: The AMOP domain (for adhesion-associated domain in MUC4 and other proteins) isan ~100-residue long extracellular domain that occurs in putative celladhesion molecules and in some splice variants of MUC4. It contains eightinvariant cysteines residues that are predicted to be involved in disulfidebonds. The AMOP domain is found associated with extracellular domains involvedin cell adhesion, such as NIDO, sushi, somatomedin B, VWFD, EGF, IPT, or TSP1. Thepresence of the AMOP domain in cell adhesion molecules could be indicative ofa role for this domain in adhesion [].Secondary structure prediction indicates an initial region rich in alpha helixfollowed by four beta strands, suggesting a β-sheet organisation for the C-terminus of the AMOP domain [].
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HT Experiment
E-GEOD-23373 | Transcript Profiling of Elf5+/- Mammary Glands During Pregnancy Identifies Novel Targets of Elf5
Series Id: GSE23373
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
11893501 | -
First Author: Ciccarelli FD
Year: 2002
Journal: Trends Biochem Sci
Title: AMOP, a protein module alternatively spliced in cancer cells.
Volume: 27
Issue: 3
Pages: 113-5
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Publication
19874420 | J:219085
First Author: Xiang W
Year: 2011
Journal: J Cell Mol Med
Title: Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumour growth in mice.
Volume: 15
Issue: 2
Pages: 359-74
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Publication
18427556 | J:136253
First Author: van der Sluis M
Year: 2008
Journal: Lab Invest
Title: Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice.
Volume: 88
Issue: 6
Pages: 634-42
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Publication
19153195 | J:154150
First Author: Schmitz JM
Year: 2009
Journal: J Histochem Cytochem
Title: Gastric mucus alterations associated with murine Helicobacter infection.
Volume: 57
Issue: 5
Pages: 457-67
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Publication
14703511 | J:88633
First Author: Wang HH
Year: 2004
Journal: J Lipid Res
Title: Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation.
Volume: 45
Issue: 3
Pages: 438-47
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Publication
15075252 | J:96078
First Author: Wang HH
Year: 2004
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1-/- mice.
Volume: 287
Issue: 3
Pages: G547-54
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Publication
25531332 | J:224797
First Author: Kumar S
Year: 2015
Journal: Oncogene
Title: NCOA3-mediated upregulation of mucin expression via transcriptional and post-translational changes during the development of pancreatic cancer.
Volume: 34
Issue: 37
Pages: 4879-89
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Publication
24675886 | J:210449
First Author: Osório L
Year: 2014
Journal: Cell Cycle
Title: Distinct spatiotemporal expression of ISM1 during mouse and chick development.
Volume: 13
Issue: 10
Pages: 1571-82
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Publication
36430789 | J:332120
 
First Author: Liu Z
Year: 2022
Journal: Int J Mol Sci
Title: Esophageal Squamous Cancer from 4NQO-Induced Mice Model: CNV Alterations.
Volume: 23
Issue: 22
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Publication
11095599 | J:66013
First Author: Danjo Y
Year: 2000
Journal: Invest Ophthalmol Vis Sci
Title: C57BL/6 mice lacking Muc1 show no ocular surface phenotype.
Volume: 41
Issue: 13
Pages: 4080-4
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Publication
24945437 | J:216833
First Author: Thiagarajah JR
Year: 2014
Journal: PLoS One
Title: Altered goblet cell differentiation and surface mucus properties in Hirschsprung disease.
Volume: 9
Issue: 6
Pages: e99944
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Publication
11581187 | J:72056
First Author: Kunert KS
Year: 2001
Journal: Invest Ophthalmol Vis Sci
Title: Alteration in goblet cell numbers and mucin gene expression in a mouse model of allergic conjunctivitis.
Volume: 42
Issue: 11
Pages: 2483-9
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Protein
Q8JZM8
Organism: Mus musculus/domesticus
Length: 3470  
Fragment?: false
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Protein
A2ATD1
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
V9GXR4
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
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Protein
A0A7N9VSW1
Organism: Mus musculus/domesticus
Length: 3990  
Fragment?: false
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Protein
D3Z6A3
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
F6YQQ5
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
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Protein
Q9DBX3
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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