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Search results 1 to 100 out of 424 for Ncoa6

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0.047s
Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Domain
Type: Family
Description: Nuclear receptor coactivator 6 (NCOA6, also known as ASC-2, TRBP and RAP250) is a general coactivator [, ]. It is involved in the coactivation of different nuclear receptors, such as steroid receptors (GR and ERs), retinoid receptors (RARs and RXRs), thyroid hormone receptors (TRs), vitamin D3 receptor (VDR) and prostanoid receptors (PPARs) []. NCOA6 possesses an LXXLL sequence motif, which mediates its interaction with nuclear receptors [, ]. Altered expression of NCOA6 may contribute to the development of certain cancers [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Caira F
Year: 2000
Journal: J Biol Chem
Title: Cloning and characterization of RAP250, a novel nuclear receptor coactivator.
Volume: 275
Issue: 8
Pages: 5308-17
Publication
First Author: Roh JI
Year: 2014
Journal: Cell Rep
Title: Perturbation of NCOA6 leads to dilated cardiomyopathy.
Volume: 8
Issue: 4
Pages: 991-8
Publication
First Author: Yoon J
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Regulation of Nampt expression by transcriptional coactivator NCOA6 in pancreatic β-cells.
Volume: 487
Issue: 3
Pages: 600-606
Protein
Organism: Mus musculus/domesticus
Length: 1511  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1753  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1169  
Fragment?: true
Publication
First Author: Ko L
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator.
Volume: 97
Issue: 11
Pages: 6212-7
Publication
First Author: Ko L
Year: 2002
Journal: Mol Endocrinol
Title: Ser-884 adjacent to the LXXLL motif of coactivator TRBP defines selectivity for ERs and TRs.
Volume: 16
Issue: 1
Pages: 128-40
Protein
Organism: Mus musculus/domesticus
Length: 2067  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2069  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 981  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1516  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1516  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 519  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1973  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1077  
Fragment?: false
Publication
First Author: Lee SK
Year: 1999
Journal: J Biol Chem
Title: A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.
Volume: 274
Issue: 48
Pages: 34283-93
Publication
First Author: Wang WL
Year: 2010
Journal: Mol Biol Cell
Title: Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of NCOA6 and result in p53-dependent and p53-independent apoptosis.
Volume: 21
Issue: 14
Pages: 2453-68
GXD Expression      
Probe: MGI:6178808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190851
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ncoa6
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6178808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190851
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ncoa6
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6178808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190851
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ncoa6
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6178808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190851
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ncoa6
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6178808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190851
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ncoa6
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6178808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190851
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ncoa6
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6178808
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190851
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ncoa6
Detected: false
Specimen Num: 7
Publication
First Author: Kawagoe J
Year: 2012
Journal: Dev Cell
Title: Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation.
Volume: 23
Issue: 4
Pages: 858-65
Publication
First Author: Oh GS
Year: 2022
Journal: Mol Cells
Title: Regulation of Hepatic Gluconeogenesis by Nuclear Receptor Coactivator 6.
Volume: 45
Issue: 4
Pages: 180-192
Publication
First Author: Li Q
Year: 2007
Journal: Mol Cell Biol
Title: Tissue- and nuclear receptor-specific function of the C-terminal LXXLL motif of coactivator NCoA6/AIB3 in mice.
Volume: 27
Issue: 23
Pages: 8073-86
Publication
First Author: Scoville DW
Year: 2015
Journal: Diabetes
Title: MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.
Volume: 64
Issue: 11
Pages: 3772-83
Publication
First Author: Kim SW
Year: 2002
Journal: Mol Cell Biol
Title: Multiple developmental defects derived from impaired recruitment of ASC-2 to nuclear receptors in mice: implication for posterior lenticonus with cataract.
Volume: 22
Issue: 24
Pages: 8409-14
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Zhang H
Year: 2004
Journal: Cancer Res
Title: Haploid inactivation of the amplified-in-breast cancer 3 coactivator reduces the inhibitory effect of peroxisome proliferator-activated receptor gamma and retinoid X receptor on cell proliferation and accelerates polyoma middle-T antigen-induced mammary tumorigenesis in mice.
Volume: 64
Issue: 19
Pages: 7169-77
Publication
First Author: Kim GH
Year: 2012
Journal: Biochem J
Title: Regulation of hepatic insulin sensitivity by activating signal co-integrator-2.
Volume: 447
Issue: 3
Pages: 437-47
Publication
First Author: Yeom SY
Year: 2006
Journal: Mol Cell Biol
Title: Regulation of insulin secretion and beta-cell mass by activating signal cointegrator 2.
Volume: 26
Issue: 12
Pages: 4553-63
Publication
First Author: Mahajan MA
Year: 2004
Journal: Mol Cell Biol
Title: The nuclear hormone receptor coactivator NRC is a pleiotropic modulator affecting growth, development, apoptosis, reproduction, and wound repair.
Volume: 24
Issue: 11
Pages: 4994-5004
Publication
First Author: Qi C
Year: 2004
Journal: J Biol Chem
Title: Null mutation of peroxisome proliferator-activated receptor-interacting protein in mammary glands causes defective mammopoiesis.
Volume: 279
Issue: 32
Pages: 33696-701
Publication
First Author: Zhu YJ
Year: 2003
Journal: J Biol Chem
Title: Coactivator PRIP, the peroxisome proliferator-activated receptor-interacting protein, is a modulator of placental, cardiac, hepatic, and embryonic development.
Volume: 278
Issue: 3
Pages: 1986-90
Publication
First Author: Mahajan MA
Year: 2000
Journal: Mol Cell Biol
Title: A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein.
Volume: 20
Issue: 14
Pages: 5048-63
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:4881555
Age: embryonic day 12.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604220
Stage: TS20
Assay Id: MGI:4881555
Age: embryonic day 12.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:4881555
Age: embryonic day 12.5
Specimen Label: Csf2-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604220
Stage: TS20
Assay Id: MGI:4881555
Age: embryonic day 12.5
Specimen Label: Csf2-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:4881652
Age: embryonic day 14.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187722
Stage: TS22
Assay Id: MGI:4881652
Age: embryonic day 14.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187622
Stage: TS22
Assay Id: MGI:4881652
Age: embryonic day 14.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:4881652
Age: embryonic day 14.5
Specimen Label: Csf2-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187722
Stage: TS22
Assay Id: MGI:4881652
Age: embryonic day 14.5
Specimen Label: Csf2-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4881446
Assay Type: RT-PCR
Annotation Date: 2011-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187622
Stage: TS22
Assay Id: MGI:4881652
Age: embryonic day 14.5
Specimen Label: Csf2-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5466308
Age: embryonic day 10.5
Image: 2
Specimen Label: 10.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5466308
Age: embryonic day 12.5
Image: 2
Specimen Label: 12.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:5466308
Age: embryonic day 14.5
Image: 2
Specimen Label: 14.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:5466308
Age: embryonic day 15.5
Image: 2
Specimen Label: 15.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:5466308
Age: embryonic day 16.5
Image: 2
Specimen Label: 16.5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:5466308
Age: embryonic day 18.5
Image: 2
Specimen Label: 18.5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5466326
Age: postnatal adult
Image: 6
Specimen Label: PC
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5466326
Age: embryonic day 3.5
Image: 6
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5466336
Age: embryonic day 3.5
Image: 6
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5466277
Assay Type: RT-PCR
Annotation Date: 2013-02-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5466336
Age: embryonic day 3.5
Image: 6
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6479917
Assay Type: RT-PCR
Annotation Date: 2020-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6480019
Age: embryonic day 9.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6479917
Assay Type: RT-PCR
Annotation Date: 2020-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6480019
Age: embryonic day 9.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6479917
Assay Type: RT-PCR
Annotation Date: 2020-12-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6480019
Age: embryonic day 9.5
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6479921
Assay Type: Western blot
Annotation Date: 2020-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6480031
Age: embryonic day 9.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6479921
Assay Type: Western blot
Annotation Date: 2020-12-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6480031
Age: embryonic day 9.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6479921
Assay Type: Western blot
Annotation Date: 2020-12-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6480031
Age: embryonic day 9.5
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:4428281
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5422598
Age: embryonic day 14.5
Specimen Label: MH2957; Specimen C4029
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4428281
Assay Type: RNA in situ
Annotation Date: 2024-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7614568
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4428281
Assay Type: RNA in situ
Annotation Date: 2024-08-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7711633
Age: embryonic day 14.5
Specimen Label: Supplementary Table 3
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4428281
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5422598
Age: embryonic day 14.5
Specimen Label: MH2957; Specimen C4029
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:4882550
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945686
Age: embryonic day 11.5
Image: g01231 E11.5
Specimen Label: g01231 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882550
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945686
Age: embryonic day 15.5
Image: g01231 E15.5
Specimen Label: g01231 E15.5
Detected: true
Specimen Num: 2