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Search results 1 to 100 out of 153 for Nek8

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Otto EA
Year: 2008
Journal: J Am Soc Nephrol
Title: NEK8 mutations affect ciliary and centrosomal localization and may cause nephronophthisis.
Volume: 19
Issue: 3
Pages: 587-92
Publication
First Author: Sohara E
Year: 2008
Journal: J Am Soc Nephrol
Title: Nek8 regulates the expression and localization of polycystin-1 and polycystin-2.
Volume: 19
Issue: 3
Pages: 469-76
Publication
First Author: Grampa V
Year: 2016
Journal: PLoS Genet
Title: Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation.
Volume: 12
Issue: 3
Pages: e1005894
Publication
First Author: Liu S
Year: 2002
Journal: Development
Title: A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish.
Volume: 129
Issue: 24
Pages: 5839-46
Publication
First Author: Trapp ML
Year: 2008
Journal: Pediatr Nephrol
Title: Defects in ciliary localization of Nek8 is associated with cystogenesis.
Volume: 23
Issue: 3
Pages: 377-87
Publication
First Author: Manning DK
Year: 2013
Journal: J Am Soc Nephrol
Title: Loss of the ciliary kinase Nek8 causes left-right asymmetry defects.
Volume: 24
Issue: 1
Pages: 100-12
Publication
First Author: Hoff S
Year: 2013
Journal: Nat Genet
Title: ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
Volume: 45
Issue: 8
Pages: 951-6
Publication
First Author: Choi HJ
Year: 2013
Journal: Mol Cell
Title: NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies.
Volume: 51
Issue: 4
Pages: 423-39
Publication  
First Author: Czarnecki PG
Year: 2015
Journal: Nat Commun
Title: ANKS6 is the critical activator of NEK8 kinase in embryonic situs determination and organ patterning.
Volume: 6
Pages: 6023
Publication
First Author: Natoli TA
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Pkd1 and Nek8 mutations affect cell-cell adhesion and cilia in cysts formed in kidney organ cultures.
Volume: 294
Issue: 1
Pages: F73-83
Publication
First Author: Shiba D
Year: 2010
Journal: Cytoskeleton (Hoboken)
Title: Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia.
Volume: 67
Issue: 2
Pages: 112-9
Publication
First Author: Mahjoub MR
Year: 2005
Journal: J Am Soc Nephrol
Title: NIMA-related kinases defective in murine models of polycystic kidney diseases localize to primary cilia and centrosomes.
Volume: 16
Issue: 12
Pages: 3485-9
Publication
First Author: Yakulov TA
Year: 2015
Journal: Kidney Int
Title: Anks3 interacts with nephronophthisis proteins and is required for normal renal development.
Volume: 87
Issue: 6
Pages: 1191-200
Publication      
First Author: Pontes R
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for nerkkod.
Publication
First Author: Fukui H
Year: 2012
Journal: FEBS Lett
Title: The ciliary protein Nek8/Nphp9 acts downstream of Inv/Nphp2 during pronephros morphogenesis and left-right establishment in zebrafish.
Volume: 586
Issue: 16
Pages: 2273-9
Publication
First Author: Smith LA
Year: 2006
Journal: J Am Soc Nephrol
Title: Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.
Volume: 17
Issue: 10
Pages: 2821-31
Publication  
First Author: McCooke JK
Year: 2012
Journal: BMC Genomics
Title: A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8.
Volume: 13
Pages: 393
Publication
First Author: Beier DR
Year: 2016
Journal: Mamm Genome
Title: High-resolution genetic localization of a modifying locus affecting disease severity in the juvenile cystic kidneys (jck) mouse model of polycystic kidney disease.
Volume: 27
Issue: 5-6
Pages: 191-9
Publication
First Author: Nakajima Y
Year: 2018
Journal: Kidney Int
Title: The Inv compartment of renal cilia is an intraciliary signal-activating center to phosphorylate ANKS6.
Volume: 93
Issue: 5
Pages: 1108-1117
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Atala A
Year: 1993
Journal: Kidney Int
Title: Juvenile cystic kidneys (jck): a new mouse mutation which causes polycystic kidneys.
Volume: 43
Issue: 5
Pages: 1081-5
Publication
First Author: Sun Y
Year: 2002
Journal: Comp Med
Title: Magnetic resonance imaging assessment of a murine model of recessive polycystic kidney disease.
Volume: 52
Issue: 5
Pages: 433-8
Publication
First Author: Panda DK
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Defective interplay between mTORC1 activity and endoplasmic reticulum stress-unfolded protein response in uremic vascular calcification.
Volume: 314
Issue: 6
Pages: F1046-F1061
Publication
First Author: Kuida S
Year: 2000
Journal: Genome Res
Title: Genetic localization of interacting modifiers affecting severity in a murine model of polycystic kidney disease.
Volume: 10
Issue: 1
Pages: 49-54
Publication
First Author: Pollard R
Year: 2006
Journal: Comp Med
Title: Ultrasound detection and characterization of polycystic kidney disease in a mouse model.
Volume: 56
Issue: 3
Pages: 215-21
Publication
First Author: Bracken C
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis.
Volume: 310
Issue: 11
Pages: F1414-22
Publication
First Author: Iakoubova OA
Year: 1997
Journal: Am J Respir Crit Care Med
Title: Genetic analysis of a quantitative trait in a mouse model of polycystic kidney disease.
Volume: 156
Issue: 4 Pt 2
Pages: S72-7
Publication
First Author: Iakoubova O
Year: 1999
Journal: Physiol Genomics
Title: Genetic analysis of modifying loci on mouse chromosome 1 that affect disease severity in a model of recessive PKD.
Volume: 1
Issue: 2
Pages: 101-5
Publication
First Author: Iakoubova OA
Year: 1995
Journal: Genomics
Title: Localization of a murine recessive polycystic kidney disease mutation and modifying loci that affect disease severity.
Volume: 26
Issue: 1
Pages: 107-14
GXD Expression      
Probe: MGI:5475297
Assay Type: Western blot
Annotation Date: 2017-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:5818043
Age: embryonic day 18.5
Specimen Label: +/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5475297
Assay Type: Western blot
Annotation Date: 2017-01-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:5818043
Age: embryonic day 18.5
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1607512
Pattern: Regionally restricted
Stage: TS12
Assay Id: MGI:5818024
Age: embryonic day 8.0
Note: Expressed in all node monocilia at base of cilia.
Specimen Label: 3I
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2017-01-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1607512
Stage: TS12
Assay Id: MGI:5818024
Age: embryonic day 8.0
Note: Not detected in nodal cilia.
Specimen Label: 3J
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2840726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5475301
Age: embryonic day 18.5
Note: Expressed in the cilia of the developing and maturing collecting ducts.
Specimen Label: 2a
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2840726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5475469
Age: embryonic day 18.5
Note: Expressed in the cilia of the developing and maturing collecting ducts.
Specimen Label: 2b
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2840728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475533
Age: postnatal day 7
Note: Expressed in the luminal cilia.
Specimen Label: a +/jck
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2840728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475533
Age: postnatal day 7
Note: Decreased expression (22%), compared with heterozygous control. Expressed in the luminal cilia.
Specimen Label: a jck/jck
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2840728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475533
Age: postnatal day 7
Note: Expressed in the luminal cilia.
Specimen Label: b +/jck
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2840728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475533
Age: postnatal day 7
Note: Expressed in the luminal cilia.
Specimen Label: b jck/jck
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1897624
Stage: TS24
Assay Id: MGI:5475301
Age: embryonic day 16.5
Note: No expression in cilia.
Specimen Label: 1b
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1897626
Stage: TS26
Assay Id: MGI:5475469
Age: embryonic day 18.5
Note: No expression in cilia.
Specimen Label: S1a
Detected: false
Specimen Num: 6
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475525
Age: postnatal day 7
Note: Expressed in the luminal cilia. Expressed in 56% cortical tubules.
Specimen Label: P7
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897627
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5475525
Age: postnatal day 1
Note: Expressed in the luminal cilia. Expressed in 41% cortical tubules.
Specimen Label: P1
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5475525
Age: embryonic day 18.5
Note: Expressed in the luminal cilia. Expressed in 29% cortical tubules.
Specimen Label: E18.5
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5475525
Age: embryonic day 16.5
Note: Expressed in the luminal cilia. Expressed in 38% cortical tubules.
Specimen Label: E16.5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5475525
Age: embryonic day 15.5
Note: Expressed in the luminal cilia. Expressed in 13% cortical tubules.
Specimen Label: E15.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1897622
Stage: TS22
Assay Id: MGI:5475525
Age: embryonic day 14.5
Note: The percentage of the ciliated tubules with expression is 0%.
Specimen Label: E14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475530
Age: postnatal day 7
Note: Expressed in the luminal cilia. Expressed in 49% cortical tubules.
Specimen Label: +/jck non-cystic
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475530
Age: postnatal day 7
Note: Decreased expression, compared with heterozygous control. Expressed in the luminal cilia. Expressed in 23% cortical tubules.
Specimen Label: jck/jck non-cystic
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1897628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475530
Age: postnatal day 7
Note: Expressed in the luminal cilia. Expressed in 26% cortical tubules. Decreased expression, compared with heterozygous control.
Specimen Label: jck/jck cystic
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5475301
Age: embryonic day 18.5
Note: Expressed in the majority of cilia of the medullary tubule.
Specimen Label: 1a
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5475301
Age: embryonic day 16.5
Note: Expressed in the majority of luminal cilia within a given medullary tubule or not at all in other ciliated medullary tubules.
Specimen Label: 1c
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5475301
Age: embryonic day 18.5
Note: Expressed in the luminal cilia of the medullary tubule.
Specimen Label: 2a
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5475469
Age: embryonic day 18.5
Note: Expressed in the luminal cilia of the medullary tubule.
Specimen Label: 2b
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475469
Age: postnatal day 7
Note: Expressed in the luminal cilia of the medullary tubule.
Specimen Label: 5a
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475469
Age: postnatal day 7
Note: Expressed in the majority of luminal cilia within a given tubule.
Specimen Label: 5b
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475469
Age: postnatal day 7
Note: Expressed in fewer cilia within a given tubule.
Specimen Label: 5c
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475469
Age: postnatal day 7
Note: Expressed in fewer cilia within a given tubule.
Specimen Label: 5d
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2778222
Stage: TS22
Assay Id: MGI:5475525
Age: embryonic day 14.5
Note: The percentage of the ciliated tubules with expression is 0%.
Specimen Label: E14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5475525
Age: embryonic day 15.5
Note: Expressed in the luminal cilia. Expressed in 42% medullary dubules, 13% in cortical tubules.
Specimen Label: E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5475525
Age: embryonic day 16.5
Note: Expressed in the luminal cilia. Expressed in 44% medullary dubules, 38% in cortical tubules.
Specimen Label: E16.5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5475525
Age: embryonic day 18.5
Note: Expressed in the luminal cilia. Expressed in 60% medullary dubules, 29% in cortical tubules.
Specimen Label: E18.5
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5475525
Age: postnatal day 1
Note: Expressed in the luminal cilia. Expressed in 72% medullary dubules, 41% in cortical tubules.
Specimen Label: P1
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475525
Age: postnatal day 7
Note: Expressed in the luminal cilia. Expressed in 66% medullary dubules, 56% in cortical tubules.
Specimen Label: P7
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2778222
Stage: TS22
Assay Id: MGI:5475528
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5475528
Age: embryonic day 15.5
Note: The majority of tubules with ciliary expression are of ureteric-bud origin. There was a population of tubules without ciliary expression.
Specimen Label: E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:5475528
Age: embryonic day 16.5
Note: The majority of tubules with ciliary expression are of ureteric-bud origin. Highest percentage of tubules of ureteric-bud origin have ciliary expression. There was a population of tubules without ciliary expression.
Specimen Label: E16.5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5475528
Age: embryonic day 18.5
Note: The majority of tubules with ciliary expression are of ureteric-bud origin. There was a population of tubules without ciliary expression.
Specimen Label: E18.5
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5475528
Age: postnatal day 1
Note: Expressed in a higher percentage of nonureteric-bud tubules. There was a population of tubules without ciliary expression.
Specimen Label: P1
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475528
Age: postnatal day 7
Note: Expressed in a higher percentage of nonureteric-bud tubules. There was a population of tubules without ciliary expression.
Specimen Label: P7
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475530
Age: postnatal day 7
Note: Expressed in the luminal cilia. Expressed in 69% medullary dubules, 49% in cortical tubules.
Specimen Label: +/jck non-cystic
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475530
Age: postnatal day 7
Note: Decreased expression, compared with heterozygous control. Expressed in the luminal cilia. Expressed in 29% medullary dubules, 23% in cortical tubules.
Specimen Label: jck/jck non-cystic
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5475297
Assay Type: Immunohistochemistry
Annotation Date: 2013-04-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2778228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5475530
Age: postnatal day 7
Note: Expressed in the luminal cilia. Expressed in 26% medullary dubules, 26% in cortical tubules. Decreased expression, compared with heterozygous control.
Specimen Label: jck/jck cystic
Detected: true
Specimen Num: 3
Publication    
First Author: Liu S
Year: 2001
Journal: GenBank Submission
Title: Mus musculus NIMA-related kinase 8 (Nek8) mRNA, complete cds
Pages: AF407579
Publication
First Author: Viau A
Year: 2010
Journal: J Clin Invest
Title: Lipocalin 2 is essential for chronic kidney disease progression in mice and humans.
Volume: 120
Issue: 11
Pages: 4065-76
Publication
First Author: Zhang JQJ
Year: 2020
Journal: Lab Invest
Title: Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease.
Volume: 100
Issue: 5
Pages: 696-711
Publication
First Author: Husson H
Year: 2016
Journal: Hum Mol Genet
Title: Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Volume: 25
Issue: 11
Pages: 2245-2255
Publication
First Author: Liu S
Year: 2014
Journal: J Bone Miner Res
Title: Role of TGF-β in a mouse model of high turnover renal osteodystrophy.
Volume: 29
Issue: 5
Pages: 1141-57