|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 931 for Nf1

<< First    < Previous  |  Next >    Last >>
0.04s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: pig, domestic
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:7384504
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7384544
Age: embryonic day 15.5
Image: 5a Nf1 WT
Note: Widely expressed throughout cortical primordium
Specimen Label: 5a Nf1 WT
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:7384504
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7384544
Age: embryonic day 15.5
Image: 5a Nf1 Fmr1 KO
Note: No difference compared with wild type.
Specimen Label: 5a Nf1 Fmr1 KO
Detected: true
Specimen Num: 2
Publication
First Author: Wu M
Year: 2006
Journal: Oncogene
Title: Nf1 haploinsufficiency augments angiogenesis.
Volume: 25
Issue: 16
Pages: 2297-303
Gene
Type: gene
Organism: human
GXD Expression    
Probe: MGI:1330081
Assay Type: Northern blot
Annotation Date: 1999-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1330576
Age: embryonic day 12.5
Image: 2
Specimen Label: NF1 +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1330081
Assay Type: Northern blot
Annotation Date: 1999-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1330576
Age: embryonic day 12.5
Image: 2
Specimen Label: NF1 +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1330081
Assay Type: Northern blot
Annotation Date: 1999-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1330576
Age: embryonic day 12.5
Image: 2
Specimen Label: NF1 -/-
Detected: true
Specimen Num: 3
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Chao RC
Year: 2005
Journal: Cancer Cell
Title: Therapy-induced malignant neoplasms in Nf1 mutant mice.
Volume: 8
Issue: 4
Pages: 337-48
Publication
First Author: Ingram DA
Year: 2003
Journal: Blood
Title: Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.
Volume: 101
Issue: 5
Pages: 1984-6
Publication
First Author: Stansfield BK
Year: 2014
Journal: Am J Pathol
Title: Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation.
Volume: 184
Issue: 1
Pages: 79-85
Publication
First Author: Birnbaum RA
Year: 2000
Journal: Mol Cell
Title: Nf1 and Gmcsf interact in myeloid leukemogenesis.
Volume: 5
Issue: 1
Pages: 189-95
Publication
First Author: Maertens O
Year: 2013
Journal: Cancer Discov
Title: Elucidating distinct roles for NF1 in melanomagenesis.
Volume: 3
Issue: 3
Pages: 338-49
Publication
First Author: Sullivan K
Year: 2014
Journal: Hum Mol Genet
Title: NF1 is a critical regulator of muscle development and metabolism.
Volume: 23
Issue: 5
Pages: 1250-9
Publication
First Author: Bajenaru ML
Year: 2003
Journal: Cancer Res
Title: Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity.
Volume: 63
Issue: 24
Pages: 8573-7
Publication
First Author: Hafezparast M
Year: 2001
Journal: Trends Mol Med
Title: NF1 mice: smaller brains but no tumours.
Volume: 7
Issue: 7
Pages: 285
Publication
First Author: Mahgoub N
Year: 1999
Journal: Blood
Title: Myeloid malignancies induced by alkylating agents in Nf1 mice.
Volume: 93
Issue: 11
Pages: 3617-23
Publication
First Author: Atit RP
Year: 1999
Journal: J Invest Dermatol
Title: The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts.
Volume: 112
Issue: 6
Pages: 835-42
Publication
First Author: Largaespada DA
Year: 1996
Journal: Nat Genet
Title: Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.
Volume: 12
Issue: 2
Pages: 137-43
Publication
First Author: Brosseau JP
Year: 2018
Journal: Nat Commun
Title: NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation.
Volume: 9
Issue: 1
Pages: 5014
Publication
First Author: Zhang Y
Year: 2001
Journal: J Clin Invest
Title: Quantitative effects of Nf1 inactivation on in vivo hematopoiesis.
Volume: 108
Issue: 5
Pages: 709-15
Publication
First Author: Toonen JA
Year: 2016
Journal: Hum Mol Genet
Title: NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1.
Volume: 25
Issue: 9
Pages: 1703-13
Publication
First Author: Pan Y
Year: 2021
Journal: Nature
Title: NF1 mutation drives neuronal activity-dependent initiation of optic glioma.
Volume: 594
Issue: 7862
Pages: 277-282
Publication
First Author: Xu J
Year: 2007
Journal: Circulation
Title: NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response.
Volume: 116
Issue: 19
Pages: 2148-56
Publication
First Author: Wang Y
Year: 2005
Journal: J Neurophysiol
Title: Sensory neurons from Nf1 haploinsufficient mice exhibit increased excitability.
Volume: 94
Issue: 6
Pages: 3670-6
Publication
First Author: Chang T
Year: 2013
Journal: J Clin Invest
Title: Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice.
Volume: 123
Issue: 1
Pages: 335-9
Publication
First Author: Gitler AD
Year: 2003
Journal: Nat Genet
Title: Nf1 has an essential role in endothelial cells.
Volume: 33
Issue: 1
Pages: 75-9
Publication
First Author: Toonen JA
Year: 2017
Journal: J Exp Med
Title: Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma-induced retinal pathology.
Volume: 214
Issue: 1
Pages: 17-25
Publication
First Author: Kim A
Year: 2007
Journal: Blood
Title: Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice.
Volume: 109
Issue: 4
Pages: 1687-91
Publication
First Author: Mayes DA
Year: 2013
Journal: Cell Rep
Title: Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature.
Volume: 4
Issue: 6
Pages: 1197-212
Publication
First Author: López-Juárez A
Year: 2017
Journal: Cell Rep
Title: Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior.
Volume: 19
Issue: 3
Pages: 545-557
Publication
First Author: Dai C
Year: 2012
Journal: J Clin Invest
Title: Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis.
Volume: 122
Issue: 10
Pages: 3742-54
Publication  
First Author: Baht GS
Year: 2017
Journal: Bone
Title: Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair.
Volume: 98
Pages: 31-36
Publication
First Author: Yin B
Year: 2009
Journal: Blood
Title: A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
Volume: 113
Issue: 5
Pages: 1075-85
Publication
First Author: Kobus K
Year: 2015
Journal: PLoS One
Title: Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient.
Volume: 10
Issue: 3
Pages: e0119030
Publication
First Author: Zhang P
Year: 2018
Journal: J Clin Invest
Title: Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy.
Volume: 128
Issue: 12
Pages: 5383-5398
Publication
First Author: de Bruin EC
Year: 2014
Journal: Cancer Discov
Title: Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.
Volume: 4
Issue: 5
Pages: 606-19
Publication
First Author: Le DT
Year: 2004
Journal: Blood
Title: Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder.
Volume: 103
Issue: 11
Pages: 4243-50
Publication
First Author: Zhu Y
Year: 2001
Journal: Genes Dev
Title: Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain.
Volume: 15
Issue: 7
Pages: 859-76
Publication
First Author: Klesse LJ
Year: 1998
Journal: J Neurosci
Title: p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons.
Volume: 18
Issue: 24
Pages: 10420-8
Publication
First Author: Mayes DA
Year: 2011
Journal: Cancer Res
Title: Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation.
Volume: 71
Issue: 13
Pages: 4675-85
Publication
First Author: Ismat FA
Year: 2006
Journal: J Clin Invest
Title: The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice.
Volume: 116
Issue: 9
Pages: 2378-84
Publication
First Author: Cutts BA
Year: 2009
Journal: Blood
Title: Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.
Volume: 114
Issue: 17
Pages: 3629-32
Publication
First Author: Powers JF
Year: 2007
Journal: Neuroscience
Title: Pheochromocytomas in Nf1 knockout mice express a neural progenitor gene expression profile.
Volume: 147
Issue: 4
Pages: 928-37
GXD Expression    
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190868
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Nf1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190868
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Nf1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190868
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Nf1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190868
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Nf1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190868
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Nf1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190868
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Nf1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190868
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Nf1
Detected: true
Specimen Num: 7
Publication
First Author: Koenigsmann J
Year: 2009
Journal: Blood
Title: Nf1 haploinsufficiency and Icsbp deficiency synergize in the development of leukemias.
Volume: 113
Issue: 19
Pages: 4690-701
Publication
First Author: Ribeiro S
Year: 2013
Journal: Cell Rep
Title: Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve.
Volume: 5
Issue: 1
Pages: 126-36
Publication
First Author: Anastasaki C
Year: 2020
Journal: Stem Cell Reports
Title: Human iPSC-Derived Neurons and Cerebral Organoids Establish Differential Effects of Germline NF1 Gene Mutations.
Volume: 14
Issue: 4
Pages: 541-550
Publication
First Author: Perrin S
Year: 2024
Journal: Sci Transl Med
Title: MEK-SHP2 inhibition prevents tibial pseudarthrosis caused by NF1 loss in Schwann cells and skeletal stem/progenitor cells.
Volume: 16
Issue: 753
Pages: eadj1597
Publication
First Author: Hawes JJ
Year: 2007
Journal: Neurogenetics
Title: Nf1 expression is dependent on strain background: implications for tumor suppressor haploinsufficiency studies.
Volume: 8
Issue: 2
Pages: 121-30
GXD Expression
Probe: MGI:1303255
Assay Type: RNA in situ
Annotation Date: 1998-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1303279
Age: embryonic day 11.5
Image: 11.5
Note: Nf1 expression was seen in the limb mesenchyme.
Specimen Label: 11.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1303255
Assay Type: RNA in situ
Annotation Date: 1998-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:1303279
Age: embryonic day 12.5
Image: 12.5
Note: Nf1 expression was seen in the limb mesenchyme.
Specimen Label: 12.5
Detected: true
Specimen Num: 3
Publication
First Author: Choi G
Year: 2012
Journal: Cancer Res
Title: Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms.
Volume: 72
Issue: 24
Pages: 6425-34
Publication
First Author: Nakamura JL
Year: 2011
Journal: Cancer Res
Title: Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice.
Volume: 71
Issue: 1
Pages: 106-15
Publication  
First Author: Jiang C
Year: 2023
Journal: J Clin Invest
Title: Basement membrane proteins in extracellular matrix characterize NF1 neurofibroma development and response to MEK inhibitor.
Volume: 133
Issue: 12
Publication
First Author: Wang W
Year: 2011
Journal: Hum Mol Genet
Title: Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.
Volume: 20
Issue: 20
Pages: 3910-24
Publication
First Author: El Khassawna T
Year: 2012
Journal: Bone
Title: Deterioration of fracture healing in the mouse model of NF1 long bone dysplasia.
Volume: 51
Issue: 4
Pages: 651-60
Publication
First Author: Wang W
Year: 2010
Journal: J Bone Miner Res
Title: Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.
Volume: 25
Issue: 7
Pages: 1658-67
Publication
First Author: Zhu Y
Year: 2005
Journal: Development
Title: Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.
Volume: 132
Issue: 24
Pages: 5577-88
Publication  
First Author: Shofty B
Year: 2019
Journal: Neurobiol Dis
Title: Autism-associated Nf1 deficiency disrupts corticocortical and corticostriatal functional connectivity in human and mouse.
Volume: 130
Pages: 104479
Publication
First Author: Li K
Year: 2016
Journal: Dis Model Mech
Title: Mice with missense and nonsense NF1 mutations display divergent phenotypes compared with human neurofibromatosis type I.
Volume: 9
Issue: 7
Pages: 759-67
Publication
First Author: Baek ST
Year: 2012
Journal: Development
Title: Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation.
Volume: 139
Issue: 11
Pages: 2040-9
Publication
First Author: Molosh AI
Year: 2014
Journal: Nat Neurosci
Title: Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase.
Volume: 17
Issue: 11
Pages: 1583-90
Publication
First Author: Xie K
Year: 2016
Journal: Curr Biol
Title: NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum.
Volume: 26
Issue: 22
Pages: 2992-3003
Publication
First Author: Wu J
Year: 2008
Journal: Cancer Cell
Title: Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.
Volume: 13
Issue: 2
Pages: 105-16
Publication
First Author: Chen L
Year: 2017
Journal: Mol Brain
Title: Abnormal circadian oscillation of hippocampal MAPK activity and power spectrums in NF1 mutant mice.
Volume: 10
Issue: 1
Pages: 29
Publication
First Author: Zhu Y
Year: 2005
Journal: Cancer Cell
Title: Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma.
Volume: 8
Issue: 2
Pages: 119-30
Publication
First Author: Rhodes SD
Year: 2015
Journal: J Bone Miner Res
Title: Nf1 Haploinsufficiency Alters Myeloid Lineage Commitment and Function, Leading to Deranged Skeletal Homeostasis.
Volume: 30
Issue: 10
Pages: 1840-51
Publication
First Author: Joseph NM
Year: 2008
Journal: Cancer Cell
Title: The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells.
Volume: 13
Issue: 2
Pages: 129-40
Publication
First Author: Summers MA
Year: 2017
Journal: Int J Dev Biol
Title: Limitations of the Pax7-creERT2 transgene for driving deletion of Nf1 in adult mouse muscle.
Volume: 61
Issue: 8-9
Pages: 531-536
Publication
First Author: Yu Y
Year: 2020
Journal: Acta Neuropathol
Title: NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.
Volume: 139
Issue: 1
Pages: 157-174
Publication
First Author: Romero MI
Year: 2007
Journal: J Neurosci
Title: Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury.
Volume: 27
Issue: 8
Pages: 2124-34
Publication
First Author: Gitler AD
Year: 2004
Journal: Pediatr Res
Title: Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia.
Volume: 55
Issue: 4
Pages: 581-4
Publication
First Author: Parrinello S
Year: 2008
Journal: Genes Dev
Title: NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F.
Volume: 22
Issue: 23
Pages: 3335-48
Publication
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
Publication
First Author: Tan M
Year: 2011
Journal: Dev Cell
Title: SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.
Volume: 21
Issue: 6
Pages: 1062-76
Publication
First Author: Dodd RD
Year: 2013
Journal: Mol Cancer Ther
Title: NF1 deletion generates multiple subtypes of soft-tissue sarcoma that respond to MEK inhibition.
Volume: 12
Issue: 9
Pages: 1906-17
Publication
First Author: Kamiya N
Year: 2017
Journal: J Bone Miner Res
Title: Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype.
Volume: 32
Issue: 8
Pages: 1716-1726
Publication
First Author: Shih YT
Year: 2020
Journal: Cell Rep
Title: Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice.
Volume: 31
Issue: 13
Pages: 107835
Publication
First Author: Mangues R
Year: 1998
Journal: Oncogene
Title: NF1 inactivation cooperates with N-ras in in vivo lymphogenesis activating Erk by a mechanism independent of its Ras-GTPase accelerating activity.
Volume: 17
Issue: 13
Pages: 1705-16