Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Neuropilins are essential multifunctional vertebrate cell surface receptors []. They function as receptors for axon guidance factor semaphorin class 3 (Sema3), vascular endothelial growth factor (VEGF) and placenta growth factor-2 (PLGF-2).Neuropilin-1 is involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, the PLGF-2 isoform of PLGF (placental growth factor), the VEGF-165 isoform of VEGF (vascular endothelial growth factor) and VEGF-B [, , , ]. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7481335 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3270422 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:7481909 |
Age: |
embryonic day 14.5 |
Image: |
2B NRP1 |
Note: |
Expression overlapping with CTIP2 (Bcl11b) expression. |
Specimen Label: |
2B NRP1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7481335 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271222 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:7481909 |
Age: |
embryonic day 14.5 |
Image: |
2B NRP1 |
Note: |
Expression overlapping with CTIP2 (Bcl11b) expression. |
Specimen Label: |
2B NRP1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7481335 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:7481909 |
Age: |
embryonic day 14.5 |
Image: |
2B NRP1 |
Note: |
Expression overlapping with CTIP2 (Bcl11b) expression. |
Specimen Label: |
2B NRP1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
He Z |
Year: |
1997 |
Journal: |
Cell |
Title: |
Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. |
Volume: |
90 |
Issue: |
4 |
Pages: |
739-51 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388574 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1894822 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:7581956 |
Age: |
embryonic day 14.5 |
Image: |
3f Nrp1 Anterior (lower) |
Note: |
Expression mainly in the anterior and middle regions of the palate. |
Specimen Label: |
3f Nrp1 Anterior (lower) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388574 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1894822 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:7581956 |
Age: |
embryonic day 14.5 |
Image: |
3f Nrp1 Middle (upper) |
Note: |
Expression mainly in the anterior and middle regions of the palate. |
Specimen Label: |
3f Nrp1 Middle (upper) |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388574 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1894822 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7581956 |
Age: |
embryonic day 14.5 |
Image: |
3f Nrp1 Posterior (upper) |
|
Specimen Label: |
3f Nrp1 Posterior (upper) |
|
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388574 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1894822 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7581956 |
Age: |
embryonic day 14.5 |
Image: |
3f Nrp1 Posterior (lower) |
|
Specimen Label: |
3f Nrp1 Posterior (lower) |
|
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388574 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1894822 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:7581956 |
Age: |
embryonic day 14.5 |
Image: |
3f Nrp1 Anterior (upper) |
Note: |
Expression mainly in the anterior and middle regions of the palate. |
Specimen Label: |
3f Nrp1 Anterior (upper) |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7388574 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-13 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1894822 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:7581956 |
Age: |
embryonic day 14.5 |
Image: |
3f Nrp1 Middle (lower) |
Note: |
Expression mainly in the anterior and middle regions of the palate. |
Specimen Label: |
3f Nrp1 Middle (lower) |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
MartÃn-Fernández F |
Year: |
2022 |
Journal: |
Elife |
Title: |
Role of Nrp1 in controlling cortical inter-hemispheric circuits. |
Volume: |
11 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Vieira JM |
Year: |
2007 |
Journal: |
Development |
Title: |
Selective requirements for NRP1 ligands during neurovascular patterning. |
Volume: |
134 |
Issue: |
10 |
Pages: |
1833-43 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4949080 |
Assay Type: |
RT-PCR |
Annotation Date: |
2011-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603912 |
|
Stage: |
TS12 |
Assay Id: |
MGI:4949101 |
Age: |
embryonic day 8.25 |
|
|
Specimen Label: |
Nrp1 Sox17-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5751869 |
Assay Type: |
Western blot |
Annotation Date: |
2023-10-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7539061 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
IP Nrp1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang SX |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Neuropilin 1 directly interacts with Fer kinase to mediate semaphorin 3A-induced death of cortical neurons. |
Volume: |
285 |
Issue: |
13 |
Pages: |
9908-18 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
923
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
837
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
840
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Parker MW |
Year: |
2012 |
Journal: |
Biochemistry |
Title: |
Function of members of the neuropilin family as essential pleiotropic cell surface receptors. |
Volume: |
51 |
Issue: |
47 |
Pages: |
9437-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soker S |
Year: |
1998 |
Journal: |
Cell |
Title: |
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. |
Volume: |
92 |
Issue: |
6 |
Pages: |
735-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gagnon ML |
Year: |
2000 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity. |
Volume: |
97 |
Issue: |
6 |
Pages: |
2573-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aspalter IM |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch. |
Volume: |
6 |
|
Pages: |
7264 |
|
•
•
•
•
•
|
Publication |
First Author: |
Telley L |
Year: |
2016 |
Journal: |
Neuron |
Title: |
Dual Function of NRP1 in Axon Guidance and Subcellular Target Recognition in Cerebellum. |
Volume: |
91 |
Issue: |
6 |
Pages: |
1276-1291 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fantin A |
Year: |
2017 |
Journal: |
J Exp Med |
Title: |
VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation. |
Volume: |
214 |
Issue: |
4 |
Pages: |
1049-1064 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fantin A |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells. |
Volume: |
11 |
Issue: |
10 |
Pages: |
1577-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Plein A |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation. |
Volume: |
125 |
Issue: |
7 |
Pages: |
2661-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tillo M |
Year: |
2015 |
Journal: |
Development |
Title: |
VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain. |
Volume: |
142 |
Issue: |
2 |
Pages: |
314-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fantin A |
Year: |
2013 |
Journal: |
Blood |
Title: |
NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis. |
Volume: |
121 |
Issue: |
12 |
Pages: |
2352-62 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4949080 |
Assay Type: |
RT-PCR |
Annotation Date: |
2011-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603912 |
|
Stage: |
TS12 |
Assay Id: |
MGI:4949101 |
Age: |
embryonic day 8.25 |
|
|
Specimen Label: |
Nrp1 Sox17+/+. Sox17+/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cariboni A |
Year: |
2011 |
Journal: |
Development |
Title: |
VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels. |
Volume: |
138 |
Issue: |
17 |
Pages: |
3723-33 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5555852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2014-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608515 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:5555940 |
Age: |
embryonic day 9.5 |
Image: |
2 E9.5 NRP1 |
Note: |
Expression is in the vasculature. |
Specimen Label: |
2 E9.5 NRP1 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5555852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2014-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608519 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5555940 |
Age: |
embryonic day 11.5 |
Image: |
2 E11.5 NRP1 |
Note: |
Expression is in the vasculature. |
Specimen Label: |
2 E11.5 NRP1 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5555852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2014-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608522 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5555940 |
Age: |
embryonic day 14.5 |
Image: |
2 E14.5 NRP1 |
Note: |
Expression is in the vasculature. |
Specimen Label: |
2 E14.5 NRP1 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5555852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2014-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608526 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:5555940 |
Age: |
embryonic day 18.5 |
Image: |
2 E18.5 NRP1 |
Note: |
Expression is in the vasculature. |
Specimen Label: |
2 E18.5 NRP1 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5555852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2014-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608519 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5555940 |
Age: |
embryonic day 11.5 |
Image: |
S2 E11.5 NRP1 |
Note: |
Expression is in the vasculature. |
Specimen Label: |
S2 E11.5 NRP1 |
Detected: |
true |
Specimen Num: |
38 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5555852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2014-04-07 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1608526 |
Pattern: |
Regionally restricted |
Stage: |
TS26 |
Assay Id: |
MGI:5555940 |
Age: |
embryonic day 18.5 |
Image: |
S2 E18.5 NRP1 |
Note: |
Expression is in the vasculature and is decreased in mature vessels. |
Specimen Label: |
S2 E18.5 NRP1 |
Detected: |
true |
Specimen Num: |
39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fantin A |
Year: |
2014 |
Journal: |
Development |
Title: |
Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis. |
Volume: |
141 |
Issue: |
3 |
Pages: |
556-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maden CH |
Year: |
2012 |
Journal: |
Dev Biol |
Title: |
NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system. |
Volume: |
369 |
Issue: |
2 |
Pages: |
277-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Assens A |
Year: |
2016 |
Journal: |
Development |
Title: |
Alteration of Nrp1 signaling at different stages of olfactory neuron maturation promotes glomerular shifts along distinct axes in the olfactory bulb. |
Volume: |
143 |
Issue: |
20 |
Pages: |
3817-3825 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cariboni A |
Year: |
2011 |
Journal: |
Hum Mol Genet |
Title: |
Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism. |
Volume: |
20 |
Issue: |
2 |
Pages: |
336-44 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179328 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190966 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Nrp1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179328 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190966 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Nrp1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179328 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190966 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Nrp1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179328 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190966 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Nrp1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179328 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190966 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Nrp1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179328 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190966 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Nrp1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179328 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190966 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Nrp1 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
95
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Seerapu HR |
Year: |
2013 |
Journal: |
FEBS Lett |
Title: |
The cytoplasmic domain of neuropilin-1 regulates focal adhesion turnover. |
Volume: |
587 |
Issue: |
21 |
Pages: |
3392-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diaz-Marin R |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity. |
Volume: |
11 |
Issue: |
1 |
Pages: |
15767 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nissen JC |
Year: |
2016 |
Journal: |
Glia |
Title: |
Tuftsin-driven experimental autoimmune encephalomyelitis recovery requires neuropilin-1. |
Volume: |
64 |
Issue: |
6 |
Pages: |
923-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Issitt T |
Year: |
2019 |
Journal: |
iScience |
Title: |
Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress. |
Volume: |
11 |
|
Pages: |
205-223 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu W |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Neuropilin-1 is upregulated by Wnt/β-catenin signaling and is important for mammary stem cells. |
Volume: |
7 |
Issue: |
1 |
Pages: |
10941 |
|
•
•
•
•
•
|
Publication |
First Author: |
Makinen T |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1. |
Volume: |
274 |
Issue: |
30 |
Pages: |
21217-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pan Q |
Year: |
2007 |
Journal: |
Cancer Cell |
Title: |
Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. |
Volume: |
11 |
Issue: |
1 |
Pages: |
53-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cantuti-Castelvetri L |
Year: |
2020 |
Journal: |
Science |
Title: |
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity. |
Volume: |
370 |
Issue: |
6518 |
Pages: |
856-860 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu C |
Year: |
2020 |
Journal: |
Nat Immunol |
Title: |
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity. |
Volume: |
21 |
Issue: |
9 |
Pages: |
1010-1021 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang F |
Year: |
2018 |
Journal: |
Science |
Title: |
Lacteal junction zippering protects against diet-induced obesity. |
Volume: |
361 |
Issue: |
6402 |
Pages: |
599-603 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson AM |
Year: |
2018 |
Journal: |
Sci Immunol |
Title: |
Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome. |
Volume: |
3 |
Issue: |
21 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Andriessen EMMA |
Year: |
2021 |
Journal: |
EMBO Mol Med |
Title: |
Myeloid-resident neuropilin-1 promotes choroidal neovascularization while mitigating inflammation. |
Volume: |
13 |
Issue: |
5 |
Pages: |
e11754 |
|
•
•
•
•
•
|
Publication |
First Author: |
Casazza A |
Year: |
2013 |
Journal: |
Cancer Cell |
Title: |
Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity. |
Volume: |
24 |
Issue: |
6 |
Pages: |
695-709 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6695212 |
Assay Type: |
Western blot |
Annotation Date: |
2023-10-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7539060 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
IP Nrp1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rossignol J |
Year: |
2022 |
Journal: |
iScience |
Title: |
Neuropilin-1 cooperates with PD-1 in CD8(+) TÂ cells predicting outcomes in melanoma patients treated with anti-PD1. |
Volume: |
25 |
Issue: |
6 |
Pages: |
104353 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gelfand MV |
Year: |
2014 |
Journal: |
Elife |
Title: |
Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding. |
Volume: |
3 |
|
Pages: |
e03720 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zapiec B |
Year: |
2016 |
Journal: |
eNeuro |
Title: |
Neuropilin-1 and the Positions of Glomeruli in the Mouse Olfactory Bulb. |
Volume: |
3 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Solomon BD |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Neuropilin-1 attenuates autoreactivity in experimental autoimmune encephalomyelitis. |
Volume: |
108 |
Issue: |
5 |
Pages: |
2040-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2016 |
Journal: |
J Cell Sci |
Title: |
Neuropilin-1 modulates interferon-γ-stimulated signaling in brain microvascular endothelial cells. |
Volume: |
129 |
Issue: |
20 |
Pages: |
3911-3921 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gioelli N |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability. |
Volume: |
13 |
Issue: |
1 |
Pages: |
4188 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
Neuropilin-1 maintains dimethylarginine dimethylaminohydrolase 1 expression in endothelial cells, and contributes to protection from angiotensin II-induced hypertension. |
Volume: |
33 |
Issue: |
1 |
Pages: |
494-500 |
|
•
•
•
•
•
|
Publication |
First Author: |
Joza S |
Year: |
2013 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Fetal, but not postnatal, deletion of semaphorin-neuropilin-1 signaling affects murine alveolar development. |
Volume: |
49 |
Issue: |
4 |
Pages: |
627-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le A |
Year: |
2009 |
Journal: |
Am J Respir Crit Care Med |
Title: |
Pulmonary epithelial neuropilin-1 deletion enhances development of cigarette smoke-induced emphysema. |
Volume: |
180 |
Issue: |
5 |
Pages: |
396-406 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roth L |
Year: |
2016 |
Journal: |
Sci Signal |
Title: |
Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation. |
Volume: |
9 |
Issue: |
425 |
Pages: |
ra42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mahmoud M |
Year: |
2019 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation. |
Volume: |
316 |
Issue: |
3 |
Pages: |
C424-C433 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wnuk M |
Year: |
2017 |
Journal: |
Kidney Int |
Title: |
Neuropilin1 regulates glomerular function and basement membrane composition through pericytes in the mouse kidney. |
Volume: |
91 |
Issue: |
4 |
Pages: |
868-879 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakanishi T |
Year: |
2019 |
Journal: |
Cell Death Dis |
Title: |
Neuropilin-1-mediated pruning of corticospinal tract fibers is required for motor recovery after spinal cord injury. |
Volume: |
10 |
Issue: |
2 |
Pages: |
67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyauchi JT |
Year: |
2018 |
Journal: |
Cancer Res |
Title: |
Deletion of Neuropilin 1 from Microglia or Bone Marrow-Derived Macrophages Slows Glioma Progression. |
Volume: |
78 |
Issue: |
3 |
Pages: |
685-694 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamaji M |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice. |
Volume: |
10 |
Issue: |
2 |
Pages: |
e0115563 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fernández-Robredo P |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Neuropilin 1 Involvement in Choroidal and Retinal Neovascularisation. |
Volume: |
12 |
Issue: |
1 |
Pages: |
e0169865 |
|
•
•
•
•
•
|
Publication |
First Author: |
Overacre-Delgoffe AE |
Year: |
2017 |
Journal: |
Cell |
Title: |
Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity. |
Volume: |
169 |
Issue: |
6 |
Pages: |
1130-1141.e11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sherafat A |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor. |
Volume: |
12 |
Issue: |
1 |
Pages: |
2265 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Anda FC |
Year: |
2012 |
Journal: |
Nat Neurosci |
Title: |
Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. |
Volume: |
15 |
Issue: |
7 |
Pages: |
1022-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lanahan A |
Year: |
2013 |
Journal: |
Dev Cell |
Title: |
The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. |
Volume: |
25 |
Issue: |
2 |
Pages: |
156-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Benhadou F |
Year: |
2020 |
Journal: |
Sci Adv |
Title: |
Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease. |
Volume: |
6 |
Issue: |
2 |
Pages: |
eaax5849 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salikhova A |
Year: |
2008 |
Journal: |
Circ Res |
Title: |
Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways. |
Volume: |
103 |
Issue: |
6 |
Pages: |
e71-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giacobini P |
Year: |
2014 |
Journal: |
PLoS Biol |
Title: |
Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A. |
Volume: |
12 |
Issue: |
3 |
Pages: |
e1001808 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dai X |
Year: |
2017 |
Journal: |
FASEB J |
Title: |
A novel role for myeloid cell-specific neuropilin 1 in mitigating sepsis. |
Volume: |
31 |
Issue: |
7 |
Pages: |
2881-2892 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shahrabi-Farahani S |
Year: |
2016 |
Journal: |
Am J Pathol |
Title: |
Neuropilin 1 Receptor Is Up-Regulated in Dysplastic Epithelium and Oral Squamous Cell Carcinoma. |
Volume: |
186 |
Issue: |
4 |
Pages: |
1055-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pinskey JM |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif. |
Volume: |
292 |
Issue: |
37 |
Pages: |
15192-15204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Venkova K |
Year: |
2014 |
Journal: |
J Neuropathol Exp Neurol |
Title: |
Semaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosis. |
Volume: |
73 |
Issue: |
7 |
Pages: |
702-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang J |
Year: |
2022 |
Journal: |
Nat Immunol |
Title: |
Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity. |
Volume: |
23 |
Issue: |
2 |
Pages: |
237-250 |
|
•
•
•
•
•
|