| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Nuclear speckles are subnuclear storage sites containing pre-mRNA splicing machinery. Nuclear speckle splicing regulatory protein 1 (Nsrp1), also known as NSRP70, is a nuclear speckle-related protein that mediates alternative splice site selection, targeting several pre-mRNAs []. It contains an N-terminal coiled-coil domain that is critical not only for self-oligomerization but also for splicing activity. It interacts physically with two SR (serine/arginine) proteins, SRSF1 and SRSF2, and reverses their splicing activity in terms of CD44 exon v5 as exon exclusion []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim YD |
| Year: |
2011 |
| Journal: |
Nucleic Acids Res |
| Title: |
NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo. |
| Volume: |
39 |
| Issue: |
10 |
| Pages: |
4300-14 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
542
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
331
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
119
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
403
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
85
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
78
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim CH |
| Year: |
2016 |
| Journal: |
J Biol Chem |
| Title: |
Nuclear Speckle-related Protein 70 Binds to Serine/Arginine-rich Splicing Factors 1 and 2 via an Arginine/Serine-like Region and Counteracts Their Alternative Splicing Activity. |
| Volume: |
291 |
| Issue: |
12 |
| Pages: |
6169-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kim CH |
| Year: |
2021 |
| Journal: |
Nucleic Acids Res |
| Title: |
NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development. |
| Volume: |
49 |
| Issue: |
10 |
| Pages: |
5760-5778 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639930 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603919 |
|
| Stage: |
TS19 |
| Assay Id: |
MGI:7639936 |
| Age: |
embryonic day 11.5 |
| Image: |
1 |
|
| Specimen Label: |
E11 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639930 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603923 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:7639936 |
| Age: |
embryonic day 15.5 |
| Image: |
1 |
|
| Specimen Label: |
E15 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639930 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603925 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:7639936 |
| Age: |
embryonic day 17.5 |
| Image: |
1 |
|
| Specimen Label: |
E17 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Brain |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Heart |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3271528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Muscle |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Thymus |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1876728 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Spleen |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Kidney |
| Detected: |
false |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684628 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Liver |
| Detected: |
false |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1672828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Lung |
| Detected: |
false |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Testis |
| Detected: |
false |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3556128 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
M.L.N. |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3552328 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
L.N. |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1702128 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
Stomach |
| Detected: |
false |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3283428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
S.I. |
| Detected: |
false |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-05-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1925228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7639937 |
| Age: |
postnatal week 8 |
| Image: |
1 |
|
| Specimen Label: |
L.I. |
| Detected: |
false |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639930 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603921 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:7639936 |
| Age: |
embryonic day 13.5 |
| Image: |
1 |
|
| Specimen Label: |
E13 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1603919 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:7639933 |
| Age: |
embryonic day 11.5 |
| Image: |
1A Embryo |
|
| Specimen Label: |
1A Embryo |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:160403 |
| Pattern: |
Not Specified |
| Stage: |
TS03 |
| Assay Id: |
MGI:7639933 |
| Age: |
embryonic day 3.0 |
| Image: |
1A Morula |
|
| Specimen Label: |
1A Morula |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7639927 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-05-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3102528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:7639933 |
| Age: |
postnatal adult |
| Image: |
1A Oocyte |
|
| Specimen Label: |
1A Oocyte |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Araki K |
| Year: |
1999 |
| Journal: |
Cell Mol Biol (Noisy-le-grand) |
| Title: |
Exchangeable gene trap using the Cre/mutated lox system. |
| Volume: |
45 |
| Issue: |
5 |
| Pages: |
737-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Taniwaki T |
| Year: |
2005 |
| Journal: |
Dev Growth Differ |
| Title: |
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. |
| Volume: |
47 |
| Issue: |
3 |
| Pages: |
163-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
| Journal: |
Database Download |
| Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI and IMPC |
| Year: |
2018 |
| Journal: |
Database Release |
| Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
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Mouse Genome Informatics Scientific Curators |
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| HT Experiment |
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RNA-Seq |
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WT vs. Mutant |
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GEO |
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