Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren Y |
Year: |
2018 |
Journal: |
Mol Genet Genomic Med |
Title: |
Functional study of a novel missense single-nucleotide variant of NUP107 in two daughters of Mexican origin with premature ovarian insufficiency. |
Volume: |
6 |
Issue: |
2 |
Pages: |
276-281 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
926
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4359201 |
Assay Type: |
Western blot |
Annotation Date: |
2009-09-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:4359296 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4359201 |
Assay Type: |
Western blot |
Annotation Date: |
2009-09-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:4359296 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4359201 |
Assay Type: |
Western blot |
Annotation Date: |
2009-09-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603915 |
|
Stage: |
TS15 |
Assay Id: |
MGI:4359296 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4359201 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2009-09-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1616415 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:4359291 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression was detected in the neuroepithelium. Staining was punctate and predominantly on the nuclear rim. |
Specimen Label: |
2A wt |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4359201 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2009-09-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1616415 |
Pattern: |
Regionally restricted |
Stage: |
TS15 |
Assay Id: |
MGI:4359291 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression was detected in the neuroepithelium, as in wild type. Staining was punctate and predominantly on the nuclear rim. |
Specimen Label: |
2A merm |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim S |
Year: |
2024 |
Journal: |
Nat Cell Biol |
Title: |
TorsinA is essential for neuronal nuclear pore complex localization and maturation. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kim CE |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. |
Volume: |
107 |
Issue: |
21 |
Pages: |
9861-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Olthof AM |
Year: |
2021 |
Journal: |
Nucleic Acids Res |
Title: |
Disruption of exon-bridging interactions between the minor and major spliceosomes results in alternative splicing around minor introns. |
Volume: |
49 |
Issue: |
6 |
Pages: |
3524-3545 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suntharalingam M |
Year: |
2003 |
Journal: |
Dev Cell |
Title: |
Peering through the pore: nuclear pore complex structure, assembly, and function. |
Volume: |
4 |
Issue: |
6 |
Pages: |
775-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lupu F |
Year: |
2008 |
Journal: |
Dev Cell |
Title: |
Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo. |
Volume: |
14 |
Issue: |
6 |
Pages: |
831-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2005 |
Journal: |
Unpublished |
Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom |
Year: |
2023 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Nuclear pore complex protein Nup107 |
Type: |
chain |
End: |
926 |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Celona B |
Year: |
2017 |
Journal: |
Elife |
Title: |
Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106. |
Volume: |
6 |
|
|
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
924
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
336
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
322
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
926
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
924
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Siniossoglou S |
Year: |
1996 |
Journal: |
Cell |
Title: |
A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores. |
Volume: |
84 |
Issue: |
2 |
Pages: |
265-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bui KH |
Year: |
2013 |
Journal: |
Cell |
Title: |
Integrated structural analysis of the human nuclear pore complex scaffold. |
Volume: |
155 |
Issue: |
6 |
Pages: |
1233-43 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Nup84 forms a complex with five proteins, including Nup120, Nup85, Sec13, and a Sec13 homologue. This Nup84 complex in conjunction with Sec13-type proteins is required for correct nuclear pore biogenesis []. Nup107 is the vertebrate homologue of Nup84. The Nup107-160 complex (Nup84 complex in yeast) forms the cytoplasmic and nucleoplasmic rings of the nuclear pore complex (NPC) scaffold, which consists of three stacked rings []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Belgareh N |
Year: |
2001 |
Journal: |
J Cell Biol |
Title: |
An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells. |
Volume: |
154 |
Issue: |
6 |
Pages: |
1147-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baï SW |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division. |
Volume: |
24 |
Issue: |
14 |
Pages: |
6379-92 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry includes the nuclear pore complex proteins Nup133, Nup132, Nup131 and Nup15 (from Caenorhabditis elegans). Nup133 is a component of the Nup160 subcomplex, which consists of Nup160, Nup133, Nup107 and Nup96, and is important for mRNA export from the nucleus []. Nup160 subcomplexes are localized to both sides of the NPC during interphase. Nup133 also localizes to kinetochores []. Nup131 and Nup132 are components of the npc107-120 complex in Schizosaccharomyces pombe. This complex consists of nup85, nup107, nup120, nup131, nup132 and seh1 and is also required for mRNA export []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Shang J |
Year: |
2017 |
Journal: |
Neuroscience |
Title: |
Aberrant distributions of nuclear pore complex proteins in ALS mice and ALS patients. |
Volume: |
350 |
|
Pages: |
158-168 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1402
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Aitchison JD |
Year: |
1995 |
Journal: |
J Cell Biol |
Title: |
Nup120p: a yeast nucleoporin required for NPC distribution and mRNA transport. |
Volume: |
131 |
Issue: |
6 Pt 2 |
Pages: |
1659-75 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Nup120 is conserved from fungi to plants to humans, and is homologous with the Nup160 of vertebrates. The nuclear core complex, or NPC, mediates macromolecular transport across the nuclear envelope. Deletion of the NUP120 gene causes clustering of NPCs at one side of the nuclear envelope, moderate nucleolar fragmentation and slower cell growth []. The vertebrate NPC is estimated to contain between 30 and 60 different proteins. most of which are not known. Two important ones in creating the nucleoporin basket are Nup98 and Nup153, and Nup120, in conjunction with Nup 133, interacts with these two and itself plays a role in mRNA export []. Nup160, Nup133, Nup96, and Nup107 are all targets of phosphorylation. The phosphorylation sites are clustered mainly at the N-terminal regions of these proteins, which are predicted to be natively disordered. The entire Nup107-160 subcomplex is stable throughout the cell cycle, thus it seems unlikely that phosphorylation affects interactions within the Nup107-160 subcomplex, but rather that it regulates the association of the subcomplex with the NPC and other proteins []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1155
|
Fragment?: |
false |
|
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1155
|
Fragment?: |
false |
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Publication |
First Author: |
Vasu S |
Year: |
2001 |
Journal: |
J Cell Biol |
Title: |
Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export. |
Volume: |
155 |
Issue: |
3 |
Pages: |
339-54 |
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•
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Publication |
First Author: |
Guo A |
Year: |
2014 |
Journal: |
Mol Cell Proteomics |
Title: |
Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. |
Volume: |
13 |
Issue: |
1 |
Pages: |
372-87 |
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•
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•
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Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
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