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Search results 1 to 77 out of 77 for Nup85

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Terashima Y
Year: 2005
Journal: Nat Immunol
Title: Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis.
Volume: 6
Issue: 8
Pages: 827-35
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2015-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Ubiquitous
Stage: TS03
Assay Id: MGI:5696813
Age: embryonic day 1.5
Specimen Label: 2A E1.5
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2015-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160414
Pattern: Ubiquitous
Stage: TS04
Assay Id: MGI:5696813
Age: embryonic day 3.5
Specimen Label: 2A E3.5
Detected: true
Specimen Num: 4
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2015-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Ubiquitous
Stage: TS03
Assay Id: MGI:5696813
Age: embryonic day 2.5
Specimen Label: 2A E2.5
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2015-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160396
Pattern: Ubiquitous
Stage: TS06
Assay Id: MGI:5696813
Age: embryonic day 4.5
Specimen Label: 2A E4.5
Detected: true
Specimen Num: 5
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2015-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160426
Pattern: Ubiquitous
Stage: TS06
Assay Id: MGI:5696813
Age: embryonic day 4.5
Specimen Label: 2A E4.5
Detected: true
Specimen Num: 5
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2015-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160403
Pattern: Ubiquitous
Stage: TS03
Assay Id: MGI:5696813
Age: embryonic day 2.5
Specimen Label: 2A E2.5
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2015-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Ubiquitous
Stage: TS04
Assay Id: MGI:5696813
Age: embryonic day 3.5
Specimen Label: 2A E3.5
Detected: true
Specimen Num: 4
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2015-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Ubiquitous
Stage: TS02
Assay Id: MGI:5696813
Age: embryonic day 1.5
Specimen Label: 2A E1.5
Detected: true
Specimen Num: 1
Protein
Organism: Mus musculus
Length: 656  
Fragment?: false
Publication
First Author: Terashima Y
Year: 2020
Journal: Nat Commun
Title: Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties.
Volume: 11
Issue: 1
Pages: 609
Publication
First Author: Suntharalingam M
Year: 2003
Journal: Dev Cell
Title: Peering through the pore: nuclear pore complex structure, assembly, and function.
Volume: 4
Issue: 6
Pages: 775-89
Publication
First Author: Dietrich JE
Year: 2015
Journal: EMBO Rep
Title: Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages.
Volume: 16
Issue: 8
Pages: 1005-21
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication
First Author: Harel A
Year: 2003
Journal: Mol Cell
Title: Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores.
Volume: 11
Issue: 4
Pages: 853-64
Protein
Organism: Mus musculus
Length: 274  
Fragment?: true
Protein
Organism: Mus musculus
Length: 280  
Fragment?: true
UniProt Feature
Begin: 1
Description: Nuclear pore complex protein Nup85
Type: chain
End: 656
DO Term
Publication
First Author: Orjalo AV
Year: 2006
Journal: Mol Biol Cell
Title: The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly.
Volume: 17
Issue: 9
Pages: 3806-18
Protein Domain
Type: Family
Description: This is a family of nucleoporins conserved from yeast to human.Nup85 Nucleoporin is an essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol-3-kinase-Rac-lammellipodium protrusion cascade [, , ]. The Nup84 complex is composed of one copy each of Nup84, Nup85, Nup120, Nup133, Nup145C, Sec13, and Seh1. The structure of a complex of Nup85 and Seh1 was solved []. The N terminus of Nup85 is inserted and forms a three-stranded blade that completes the Seh1 6-bladed β-propeller in trans. Following its N-terminal insertion blade, Nup85 forms a compact cuboid structure composed of 20 helices, with two distinct modules, referred to as crown and trunk [].
Publication
First Author: Brohawn SG
Year: 2008
Journal: Science
Title: Structural evidence for common ancestry of the nuclear pore complex and vesicle coats.
Volume: 322
Issue: 5906
Pages: 1369-73
Publication
First Author: Park J
Year: 2013
Journal: Mol Cell
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Volume: 50
Issue: 6
Pages: 919-30
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112