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Search results 1 to 100 out of 388 for Opn4

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
94233 | OPN4
Type: gene
Organism: human
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Gene
100491785 | opn4
Type: gene
Organism: frog, western clawed
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Gene
107966782 | OPN4
Type: gene
Organism: chimpanzee
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Gene
192223 | Opn4
Type: gene
Organism: rat
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Gene
611027 | OPN4
Type: gene
Organism: dog, domestic
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Gene
515152 | OPN4
Type: gene
Organism: cattle
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Gene
423609 | OPN4
Type: gene
Organism: chicken
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Gene
699800 | OPN4
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1353425 | Opn4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
39127043 | J:369528
First Author: Dyer B
Year: 2024
Journal: Cell Rep Methods
Title: Defining spatial nonuniformities of all ipRGC types using an improved Opn4(cre) recombinase mouse line.
Volume: 4
Issue: 8
Pages: 100837
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Publication
25253855 | J:216608
First Author: Mao CA
Year: 2014
Journal: J Neurosci
Title: T-box transcription regulator Tbr2 is essential for the formation and maintenance of Opn4/melanopsin-expressing intrinsically photosensitive retinal ganglion cells.
Volume: 34
Issue: 39
Pages: 13083-95
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Publication
39694031 | J:388263
First Author: Shi Y
Year: 2025
Journal: Neuron
Title: Non-image-forming photoreceptors improve visual orientation selectivity and image perception.
Volume: 113
Issue: 3
Pages: 486-500.e13
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Publication
26207303 | J:230956
First Author: Vartanian GV
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Using Flickering Light to Enhance Nonimage-Forming Visual Stimulation in Humans.
Volume: 56
Issue: 8
Pages: 4680-8
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Publication
28223508 | J:241647
First Author: Somasundaram P
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: C-terminal phosphorylation regulates the kinetics of a subset of melanopsin-mediated behaviors in mice.
Volume: 114
Issue: 10
Pages: 2741-2746
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Publication
38951486 | J:352323
First Author: Zangen E
Year: 2024
Journal: Nat Commun
Title: Prefrontal cortex neurons encode ambient light intensity differentially across regions and layers.
Volume: 15
Issue: 1
Pages: 5501
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Publication
22895730 | J:187716
First Author: Wong KY
Year: 2012
Journal: J Neurosci
Title: A retinal ganglion cell that can signal irradiance continuously for 10 hours.
Volume: 32
Issue: 33
Pages: 11478-85
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Publication
27893096 | J:257596
First Author: Milosavljevic N
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Chemogenetic Activation of ipRGCs Drives Changes in Dark-Adapted (Scotopic) Electroretinogram.
Volume: 57
Issue: 14
Pages: 6305-6312
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Publication
19793992 | J:158237
First Author: Pires SS
Year: 2009
Journal: J Neurosci
Title: Differential expression of two distinct functional isoforms of melanopsin (Opn4) in the mammalian retina.
Volume: 29
Issue: 39
Pages: 12332-42
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Publication
29950974 | J:263286
 
First Author: Wen X
Year: 2018
Journal: Front Cell Neurosci
Title: Elevated Pressure Increases Ca(2+) Influx Through AMPA Receptors in Select Populations of Retinal Ganglion Cells.
Volume: 12
Pages: 162
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Publication
28965762 | J:252494
First Author: Milner ES
Year: 2017
Journal: Cell
Title: A Population Representation of Absolute Light Intensity in the Mammalian Retina.
Volume: 171
Issue: 4
Pages: 865-876.e16
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Publication
23189207 | J:195574
First Author: Liu X
Year: 2012
Journal: PLoS One
Title: Heterogeneous expression of the core circadian clock proteins among neuronal cell types in mouse retina.
Volume: 7
Issue: 11
Pages: e50602
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Publication
25357191 | J:223088
First Author: Purrier N
Year: 2014
Journal: PLoS One
Title: Mice deficient of glutamatergic signaling from intrinsically photosensitive retinal ganglion cells exhibit abnormal circadian photoentrainment.
Volume: 9
Issue: 10
Pages: e111449
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Publication
25512304 | J:235116
First Author: Gompf HS
Year: 2015
Journal: J Biol Rhythms
Title: Impaired circadian photosensitivity in mice lacking glutamate transmission from retinal melanopsin cells.
Volume: 30
Issue: 1
Pages: 35-41
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Publication
23954426 | J:252667
First Author: Hughes S
Year: 2013
Journal: Curr Biol
Title: Nonuniform distribution and spectral tuning of photosensitive retinal ganglion cells of the mouse retina.
Volume: 23
Issue: 17
Pages: 1696-701
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Publication
28617242 | J:256669
   
First Author: Chew KS
Year: 2017
Journal: Elife
Title: A subset of ipRGCs regulates both maturation of the circadian clock and segregation of retinogeniculate projections in mice.
Volume: 6
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Publication
30311650 | J:287246
First Author: Quattrochi LE
Year: 2019
Journal: J Comp Neurol
Title: The M6 cell: A small-field bistratified photosensitive retinal ganglion cell.
Volume: 527
Issue: 1
Pages: 297-311
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Publication
33410914 | J:300135
First Author: Harrison KR
Year: 2021
Journal: Invest Ophthalmol Vis Sci
Title: Amacrine Cells Forming Gap Junctions With Intrinsically Photosensitive Retinal Ganglion Cells: ipRGC Types, Neuromodulator Contents, and Connexin Isoform.
Volume: 62
Issue: 1
Pages: 10
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Publication
31362954 | J:278716
 
First Author: Lin CI
Year: 2019
Journal: eNeuro
Title: Blue Light Promotes Neurite Outgrowth of Retinal Explants in Postnatal ChR2 Mice.
Volume: 6
Issue: 4
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Publication
26895233 | J:252398
First Author: Delwig A
Year: 2016
Journal: PLoS One
Title: Retinofugal Projections from Melanopsin-Expressing Retinal Ganglion Cells Revealed by Intraocular Injections of Cre-Dependent Virus.
Volume: 11
Issue: 2
Pages: e0149501
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Publication
41620469 | J:380949
 
First Author: Kiyama T
Year: 2026
Journal: Commun Biol
Title: Tbr2-dependent parallel pathways regulate the development of distinct ipRGC subtypes.
Volume: 9
Issue: 1
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Publication
26320947 | J:252142
First Author: Jagannath A
Year: 2015
Journal: Curr Biol
Title: Isoforms of Melanopsin Mediate Different Behavioral Responses to Light.
Volume: 25
Issue: 18
Pages: 2430-4
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Publication
34556572 | J:311471
 
First Author: Tam SKE
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Dim light in the evening causes coordinated realignment of circadian rhythms, sleep, and short-term memory.
Volume: 118
Issue: 39
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Publication
25404319 | J:216731
First Author: Sikka G
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Melanopsin mediates light-dependent relaxation in blood vessels.
Volume: 111
Issue: 50
Pages: 17977-82
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Publication
31607867 | J:311183
 
First Author: Bhandari A
Year: 2019
Journal: Front Cell Neurosci
Title: Early-Stage Ocular Hypertension Alters Retinal Ganglion Cell Synaptic Transmission in the Visual Thalamus.
Volume: 13
Pages: 426
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Publication
41150857 | J:377062
First Author: Brown TW
Year: 2025
Journal: Cell Rep
Title: Retinal glia regulate development of the circadian photoentrainment circuit.
Volume: 44
Issue: 11
Pages: 116464
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Publication
29888785 | J:277772
First Author: Li JY
Year: 2018
Journal: J Comp Neurol
Title: Divergent projection patterns of M1 ipRGC subtypes.
Volume: 526
Issue: 13
Pages: 2010-2018
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Publication
26069965 | J:237821
First Author: Sexton TJ
Year: 2015
Journal: PLoS One
Title: G-Protein Coupled Receptor Kinase 2 Minimally Regulates Melanopsin Activity in Intrinsically Photosensitive Retinal Ganglion Cells.
Volume: 10
Issue: 6
Pages: e0128690
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Publication
29756029 | J:266789
 
First Author: Moldavan MG
Year: 2018
Journal: eNeuro
Title: Circadian Behavioral Responses to Light and Optic Chiasm-Evoked Glutamatergic EPSCs in the Suprachiasmatic Nucleus of ipRGC Conditional vGlut2 Knock-Out Mice.
Volume: 5
Issue: 3
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Publication
38552022 | J:370563
First Author: Lazzerini Ospri L
Year: 2024
Journal: Sci Adv
Title: Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells.
Volume: 10
Issue: 13
Pages: eadh9251
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Publication
24391855 | J:211116
First Author: Delwig A
Year: 2013
Journal: PLoS One
Title: Glutamatergic neurotransmission from melanopsin retinal ganglion cells is required for neonatal photoaversion but not adult pupillary light reflex.
Volume: 8
Issue: 12
Pages: e83974
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Publication
31708397 | J:314867
First Author: Caval-Holme F
Year: 2019
Journal: Curr Biol
Title: Gap Junction Coupling Shapes the Encoding of Light in the Developing Retina.
Volume: 29
Issue: 23
Pages: 4024-4035.e5
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Publication
29905117 | J:285371
 
First Author: Delwig A
Year: 2018
Journal: Vis Neurosci
Title: Melanopsin expression in the cornea.
Volume: 35
Pages: E004
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Publication
38375612 | J:349303
First Author: Maloney R
Year: 2024
Journal: J Comp Neurol
Title: Efficacy and specificity of melanopsin reporters for retinal ganglion cells.
Volume: 532
Issue: 2
Pages: e25591
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Publication
27992553 | J:253189
First Author: Kofuji P
Year: 2016
Journal: PLoS One
Title: Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Are Necessary for Light Entrainment of Peripheral Clocks.
Volume: 11
Issue: 12
Pages: e0168651
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Publication
32543667 | J:295391
First Author: D?az NM
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea.
Volume: 61
Issue: 6
Pages: 37
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Publication
24396062 | J:219912
First Author: Zhao X
Year: 2014
Journal: J Physiol
Title: Photoresponse diversity among the five types of intrinsically photosensitive retinal ganglion cells.
Volume: 592
Issue: 7
Pages: 1619-36
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Publication
36385954 | J:331438
 
First Author: Procyk CA
Year: 2022
Journal: Front Cell Neurosci
Title: Quantitative characterisation of ipRGCs in retinal degeneration using a computation platform for extracting and reconstructing single neurons in 3D from a multi-colour labeled population.
Volume: 16
Pages: 1009321
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Publication
33584206 | J:365872
 
First Author: Van Hook MJ
Year: 2020
Journal: Front Cell Neurosci
Title: Neuronal and Synaptic Plasticity in the Visual Thalamus in Mouse Models of Glaucoma.
Volume: 14
Pages: 626056
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Publication
21418557 | J:171705
 
First Author: McNeill DS
Year: 2011
Journal: Neural Dev
Title: Development of melanopsin-based irradiance detecting circuitry.
Volume: 6
Pages: 8
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Publication
41419332 | J:385736
 
First Author: Liao BZ
Year: 2026
Journal: J Neurosci
Title: Prolonged Light Exposure Induces Long-Lasting Retinal Wave Plasticity via Retrograde Melanopsin-Dopamine Signaling.
Volume: 46
Issue: 4
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Publication
35396331 | J:353005
First Author: Caval-Holme FS
Year: 2022
Journal: J Neurosci
Title: The Retinal Basis of Light Aversion in Neonatal Mice.
Volume: 42
Issue: 20
Pages: 4101-4115
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Publication
35883647 | J:327438
 
First Author: Kiyama T
Year: 2022
Journal: Cells
Title: Differential Susceptibility of Retinal Neurons to the Loss of Mitochondrial Biogenesis Factor Nrf1.
Volume: 11
Issue: 14
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Publication
34433830 | J:312787
First Author: Zhang Z
Year: 2021
Journal: Nat Commun
Title: The retinal ipRGC-preoptic circuit mediates the acute effect of light on sleep.
Volume: 12
Issue: 1
Pages: 5115
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Publication
24853938 | J:214305
First Author: Schmidt TM
Year: 2014
Journal: Neuron
Title: A role for melanopsin in alpha retinal ganglion cells and contrast detection.
Volume: 82
Issue: 4
Pages: 781-8
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Publication
23762490 | J:204239
First Author: Weng S
Year: 2013
Journal: PLoS One
Title: Mouse ganglion-cell photoreceptors are driven by the most sensitive rod pathway and by both types of cones.
Volume: 8
Issue: 6
Pages: e66480
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Publication
37531065 | J:348919
First Author: Huang YF
Year: 2023
Journal: EMBO Rep
Title: Light disrupts social memory via a retina-to-supraoptic nucleus circuit.
Volume: 24
Issue: 10
Pages: e56839
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Publication
34873237 | J:319414
First Author: Sheng Y
Year: 2021
Journal: Sci Rep
Title: Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells.
Volume: 11
Issue: 1
Pages: 23424
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Publication
24958088 | J:232057
First Author: Hughes S
Year: 2015
Journal: Cell Mol Life Sci
Title: Using siRNA to define functional interactions between melanopsin and multiple G Protein partners.
Volume: 72
Issue: 1
Pages: 165-79
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Publication
34954202 | J:322287
 
First Author: Chambers S
Year: 2022
Journal: Exp Eye Res
Title: Trpm1: Novel function at the intersection of light and pain response in the iris.
Volume: 215
Pages: 108897
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Publication
23334418 | J:194554
First Author: Rao S
Year: 2013
Journal: Nature
Title: A direct and melanopsin-dependent fetal light response regulates mouse eye development.
Volume: 494
Issue: 7436
Pages: 243-6
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Publication
21765429 | J:174940
First Author: Chen SK
Year: 2011
Journal: Nature
Title: Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs.
Volume: 476
Issue: 7358
Pages: 92-5
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Publication
36932080 | J:334964
First Author: Berry MH
Year: 2023
Journal: Nat Commun
Title: A melanopsin ganglion cell subtype forms a dorsal retinal mosaic projecting to the supraoptic nucleus.
Volume: 14
Issue: 1
Pages: 1492
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Publication
33397711 | J:302602
First Author: Pottackal J
Year: 2021
Journal: J Neurosci
Title: Photoreceptive Ganglion Cells Drive Circuits for Local Inhibition in the Mouse Retina.
Volume: 41
Issue: 7
Pages: 1489-1504
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Publication
32355031 | J:287618
First Author: Sonoda T
Year: 2020
Journal: Science
Title: A noncanonical inhibitory circuit dampens behavioral sensitivity to light.
Volume: 368
Issue: 6490
Pages: 527-531
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Publication
26831088 | J:230434
First Author: Li S
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Promoting axon regeneration in the adult CNS by modulation of the melanopsin/GPCR signaling.
Volume: 113
Issue: 7
Pages: 1937-42
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Publication
30017393 | J:269396
First Author: Sonoda T
Year: 2018
Journal: Neuron
Title: Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.
Volume: 99
Issue: 4
Pages: 754-767.e4
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Publication
31333190 | J:278489
   
First Author: Rupp AC
Year: 2019
Journal: Elife
Title: Distinct ipRGC subpopulations mediate light's acute and circadian effects on body temperature and sleep.
Volume: 8
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Publication
29959210 | J:264212
First Author: Fan SM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: External light activates hair follicle stem cells through eyes via an ipRGC-SCN-sympathetic neural pathway.
Volume: 115
Issue: 29
Pages: E6880-E6889
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Publication
40038284 | J:369458
First Author: Zhang X
Year: 2025
Journal: Nat Commun
Title: Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement.
Volume: 16
Issue: 1
Pages: 2174
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Publication
30799247 | J:286021
First Author: P?rez-Fern?ndez V
Year: 2019
Journal: Curr Biol
Title: Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina.
Volume: 29
Issue: 5
Pages: 763-774.e5
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Publication
36790167 | J:363947
   
First Author: Voufo C
Year: 2023
Journal: Elife
Title: Circuit mechanisms underlying embryonic retinal waves.
Volume: 12
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Publication
31387875 | J:285474
 
First Author: Berg DJ
Year: 2019
Journal: eNeuro
Title: Transcriptomic Signatures of Postnatal and Adult Intrinsically Photosensitive Ganglion Cells.
Volume: 6
Issue: 4
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Publication
39359403 | J:376618
First Author: Lee T
Year: 2024
Journal: PNAS Nexus
Title: Specific retinal neurons regulate context-dependent defensive responses to visual threat.
Volume: 3
Issue: 10
Pages: pgae423
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Publication
42406594 | J:390366
First Author: Daly KM
Year: 2026
Journal: Cell Rep
Title: M4-ipRGCs regulate contrast sensitivity in vision.
Volume: 45
Issue: 7
Pages: 117662
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Publication
41501453 | J:385931
First Author: Komal R
Year: 2026
Journal: Nature
Title: ipRGC properties prevent light from shifting the SCN clock during daytime.
Volume: 650
Issue: 8103
Pages: 942-950
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Publication
20624591 | J:167871
First Author: Ecker JL
Year: 2010
Journal: Neuron
Title: Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision.
Volume: 67
Issue: 1
Pages: 49-60
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Publication
31968245 | J:287419
First Author: Nayak G
Year: 2020
Journal: Cell Rep
Title: Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing.
Volume: 30
Issue: 3
Pages: 672-686.e8
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Publication
37624696 | J:339658
First Author: Zhao M
Year: 2023
Journal: Cell Rep
Title: Osteopontin drives retinal ganglion cell resiliency in glaucomatous optic neuropathy.
Volume: 42
Issue: 9
Pages: 113038
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Publication
40840447 | J:376892
First Author: Nimkar K
Year: 2025
Journal: Neuron
Title: Molecular and spatial analysis of ganglion cells on retinal flatmounts identifies perivascular neurons resilient to glaucoma.
Volume: 113
Issue: 20
Pages: 3390-3407.e8
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Protein Coding Gene
MGP_CAROLIEiJ_G0019124 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021178 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021126 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021130 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020913 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1353425 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021562 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020879 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021002 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020986 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021071 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021012 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020186 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020493 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030141 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020010 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10632589 | J:59329
First Author: Provencio I
Year: 2000
Journal: J Neurosci
Title: A novel human opsin in the inner retina.
Volume: 20
Issue: 2
Pages: 600-5
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Publication
11834834 | J:81604
First Author: Hattar S
Year: 2002
Journal: Science
Title: Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity.
Volume: 295
Issue: 5557
Pages: 1065-70
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom