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Search results 1 to 100 out of 107 for Pear1

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0.076s
Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: zebrafish
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
First Author: Roquid KA
Year: 2025
Journal: Mol Cancer
Title: Lung endothelial PEAR1 induces tumor cell dormancy.
Volume: 24
Issue: 1
Pages: 278
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Publication  
First Author: Criel M
Year: 2016
Journal: Thromb Res
Title: Absence of Pear1 does not affect murine platelet function in vivo.
Volume: 146
Pages: 76-83
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Publication
First Author: Geng Y
Year: 2022
Journal: Nat Commun
Title: PEAR1 regulates expansion of activated fibroblasts and deposition of extracellular matrix in pulmonary fibrosis.
Volume: 13
Issue: 1
Pages: 7114
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Publication
First Author: Kardeby C
Year: 2019
Journal: Blood Adv
Title: Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIb?.
Volume: 3
Issue: 3
Pages: 275-287
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Publication
First Author: Vandenbriele C
Year: 2015
Journal: Cardiovasc Res
Title: Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.
Volume: 108
Issue: 1
Pages: 124-38
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Publication
First Author: Elenbaas JS
Year: 2023
Journal: Nat Commun
Title: SVEP1 is an endogenous ligand for the orphan receptor PEAR1.
Volume: 14
Issue: 1
Pages: 850
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Publication
First Author: Vandenbriele C
Year: 2016
Journal: Platelets
Title: Dextran sulfate triggers platelet aggregation via direct activation of PEAR1.
Volume: 27
Issue: 4
Pages: 365-72
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Publication
First Author: Cui YF
Year: 2018
Journal: Exp Cell Res
Title: Platelet endothelial aggregation receptor-1 (PEAR1) is involved in C2C12 myoblast differentiation.
Volume: 366
Issue: 2
Pages: 199-204
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
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Publication
First Author: Trevisan AJ
Year: 2020
Journal: Sci Rep
Title: Jedi-1 deficiency increases sensory neuron excitability through a non-cell autonomous mechanism.
Volume: 10
Issue: 1
Pages: 1300
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GXD Expression    
Probe: MGI:5701478
Assay Type: RT-PCR
Annotation Date: 2016-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:5701502
Age: embryonic day 12.5
Image: 4
Specimen Label: Brain
Detected: true
Specimen Num: 2
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GXD Expression    
Probe: MGI:5701478
Assay Type: RT-PCR
Annotation Date: 2016-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:5701502
Age: embryonic day 12.5
Image: 4
Specimen Label: Heart
Detected: true
Specimen Num: 3
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GXD Expression      
Probe: MGI:5701478
Assay Type: RT-PCR
Annotation Date: 2016-01-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1757720
Stage: TS20
Assay Id: MGI:5701502
Age: embryonic day 12.5
Image: 4
Specimen Label: SpC
Specimen Num: 4
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GXD Expression    
Probe: MGI:5701478
Assay Type: RT-PCR
Annotation Date: 2016-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666820
Stage: TS20
Assay Id: MGI:5701502
Age: embryonic day 12.5
Image: 4
Specimen Label: DRG
Detected: true
Specimen Num: 5
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GXD Expression      
Probe: MGI:5701478
Assay Type: RT-PCR
Annotation Date: 2016-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:5701511
Age: embryonic day 15.0
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:5701481
Assay Type: RNA in situ
Annotation Date: 2016-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5701506
Age: embryonic day 12.5
Image: 4c E12.5
Note: Expression was detected in the dorsal root ganglion and developing glial cells alongside axons.
Specimen Label: 4c E12.5
Detected: true
Specimen Num: 1
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GXD Expression
Probe: MGI:5701481
Assay Type: RNA in situ
Annotation Date: 2016-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5701506
Age: embryonic day 15.5
Image: 4c E15.5
Note: Expression was detected in the dorsal root ganglion and developing glial cells alongside axons.
Specimen Label: 4c E15.5
Detected: true
Specimen Num: 2
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GXD Expression
Probe: MGI:5701481
Assay Type: RNA in situ
Annotation Date: 2016-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666825
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5701506
Age: embryonic day 17.5
Image: 4c E17.5
Note: Expression was detected in the dorsal root ganglion and developing glial cells alongside axons.
Specimen Label: 4c E17.5
Detected: true
Specimen Num: 3
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Publication
First Author: Morrison V
Year: 2023
Journal: Cell Rep
Title: Jedi-1/MEGF12-mediated phagocytosis controls the pro-neurogenic properties of microglia in the ventricular-subventricular zone.
Volume: 42
Issue: 11
Pages: 113423
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Publication
First Author: Wu HH
Year: 2009
Journal: Nat Neurosci
Title: Glial precursors clear sensory neuron corpses during development via Jedi-1, an engulfment receptor.
Volume: 12
Issue: 12
Pages: 1534-41
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Publication
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 2
Pages: 127-35
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Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication        
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication      
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
First Author: Herrera-Galeano JE
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: A novel variant in the platelet endothelial aggregation receptor-1 gene is associated with increased platelet aggregability.
Volume: 28
Issue: 8
Pages: 1484-90
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Protein Domain
Type: Domain
Description: This domain is found in human Platelet endothelial aggregation receptor 1 (PEAR1L) and related proteins such as Multiple epidermal growth factor-like domains protein 10 and 11 (MEGF10 and MEGF11).Platelet Endothelial Aggregation Receptor 1 (PEAR1) is a type I transmembrane protein that plays a significant role in both platelet and endothelial cell functions. PEAR1 is required for SVEP1-mediated platelet activation, via its interaction with SVEP1 and subsequent activation of AKT/mTOR signaling []. PEAR1 influences endothelial cell migration and angiogenesis. Knockdown of PEAR1 enhances endothelial cell proliferation, migration, and tube formation via Akt/PTEN pathways []. PEAR1 also plays a role in stabilising platelet thrombi during vascular injury [].MEGF10 is a membrane receptor involved in phagocytosis by macrophages and astrocytes of apoptotic cells.
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Protein
Organism: Mus musculus/domesticus
Length: 50  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Publication
First Author: Malinauskas T
Year: 2011
Journal: Nat Struct Mol Biol
Title: Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1.
Volume: 18
Issue: 8
Pages: 886-93
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Protein
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1034  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1095  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 474  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 820  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1147  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1091  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 833  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 1061  
Fragment?: true
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Protein
Organism: Mus musculus/domesticus
Length: 566  
Fragment?: false
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Protein
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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