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Search results 1 to 92 out of 92 for Pkp2

0.026s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Moncayo-Arlandi J
Year: 2016
Journal: Hum Mol Genet
Title: Molecular disturbance underlies to arrhythmogenic cardiomyopathy induced by transgene content, age and exercise in a truncated PKP2 mouse model.
Volume: 25
Issue: 17
Pages: 3676-3688
GXD Expression      
Probe: MGI:6180719
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6191088
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pkp2
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6180719
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191088
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pkp2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6180719
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191088
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pkp2
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6180719
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191088
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pkp2
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6180719
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6191088
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pkp2
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6180719
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191088
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pkp2
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6180719
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191088
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pkp2
Detected: true
Specimen Num: 7
Publication
First Author: Sugimoto M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Genetic variants related to gap junctions and hormone secretion influence conception rates in cows.
Volume: 110
Issue: 48
Pages: 19495-500
Publication
First Author: Cerrone M
Year: 2012
Journal: Cardiovasc Res
Title: Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency.
Volume: 95
Issue: 4
Pages: 460-8
Publication
First Author: Cerrone M
Year: 2017
Journal: Nat Commun
Title: Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm.
Volume: 8
Issue: 1
Pages: 106
Publication
First Author: Cerrone M
Year: 2014
Journal: Circulation
Title: Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype.
Volume: 129
Issue: 10
Pages: 1092-103
Publication
First Author: Hammer KP
Year: 2021
Journal: PLoS One
Title: Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice.
Volume: 16
Issue: 6
Pages: e0252649
Publication
First Author: Dubash AD
Year: 2016
Journal: J Cell Biol
Title: Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes.
Volume: 212
Issue: 4
Pages: 425-38
Publication
First Author: Gurha P
Year: 2016
Journal: Circ Res
Title: Knockdown of Plakophilin 2 Downregulates miR-184 Through CpG Hypermethylation and Suppression of the E2F1 Pathway and Leads to Enhanced Adipogenesis In Vitro.
Volume: 119
Issue: 6
Pages: 731-50
Publication
First Author: Kim JC
Year: 2019
Journal: Circulation
Title: Disruption of Ca2+i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice.
Volume: 140
Issue: 12
Pages: 1015-1030
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:6407093
Assay Type: RT-PCR
Annotation Date: 2020-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Stage: TS21
Assay Id: MGI:6416445
Age: embryonic day 13.5
Image: 6
Specimen Label: Nf2;Emx1-Cre dorsal telencephalon
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6407093
Assay Type: RT-PCR
Annotation Date: 2020-05-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Stage: TS21
Assay Id: MGI:6416445
Age: embryonic day 13.5
Image: 6
Specimen Label: control dorsal telencephalon
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4948308
Assay Type: Immunohistochemistry
Annotation Date: 2011-04-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4948339
Age: postnatal adult
Note: This is a prototypical area composita protein.
Specimen Label: Myozap/Plakophilin2
Detected: true
Specimen Num: 1
Publication    
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, similar to RIKEN cDNA 1200008D14 gene, clone IMAGE:2647452, mRNA
Pages: BC018487
Publication
First Author: Seeger TS
Year: 2010
Journal: Circ Res
Title: Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo.
Volume: 106
Issue: 5
Pages: 880-90
Publication
First Author: Thomas NM
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Sex differences in expression and subcellular localization of heart rhythm determinant proteins.
Volume: 406
Issue: 1
Pages: 117-22
Publication
First Author: Yang Z
Year: 2006
Journal: Circ Res
Title: Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Volume: 99
Issue: 6
Pages: 646-55
Publication
First Author: Goossens S
Year: 2007
Journal: J Cell Sci
Title: A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs.
Volume: 120
Issue: Pt 12
Pages: 2126-36
Publication
First Author: Gallicano GI
Year: 1998
Journal: J Cell Biol
Title: Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage.
Volume: 143
Issue: 7
Pages: 2009-22
Publication
First Author: Grossmann KS
Year: 2004
Journal: J Cell Biol
Title: Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
Volume: 167
Issue: 1
Pages: 149-60
Publication  
First Author: Ragni CV
Year: 2017
Journal: Nat Commun
Title: Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.
Volume: 8
Pages: 14582
Publication  
First Author: Godsel LM
Year: 2022
Journal: J Clin Invest
Title: Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.
Volume: 132
Issue: 3
Publication
First Author: Romano RA
Year: 2012
Journal: Development
Title: ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.
Volume: 139
Issue: 4
Pages: 772-82
Publication
First Author: Lavado A
Year: 2013
Journal: Development
Title: Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.
Volume: 140
Issue: 16
Pages: 3323-34
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Allele
Name: transgene insertion 5, Ramon Brugada
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Allele
Name: transgene insertion 4, Ramon Brugada
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
Genotype
Symbol: Tg(Myh6-Pkp2*/mRuby)4Rbrug/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Pkp2*/mRuby)5Rbrug/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Myh6-Pkp2*/mRuby)4Rbrug/? Tg(Myh6-Pkp2*/mRuby)5Rbrug/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cx
Has Mutant Allele: true
Transgene
Type: transgene
Organism: Mus musculus
Transgene
Type: transgene
Organism: Mus musculus
DO Term
Publication
First Author: Li J
Year: 2012
Journal: J Cell Sci
Title: Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia.
Volume: 125
Issue: Pt 4
Pages: 1058-67
Publication
First Author: Chen SN
Year: 2014
Journal: Circ Res
Title: The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy.
Volume: 114
Issue: 3
Pages: 454-68
Publication  
First Author: Hofmann I
Year: 2000
Journal: J Cell Sci
Title: Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis.
Volume: 113 ( Pt 13)
Pages: 2471-83