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Search results 1 to 100 out of 152 for Polq

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0.048s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Li Y
Year: 2011
Journal: Genes Cells
Title: Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells.
Volume: 16
Issue: 9
Pages: 973-83
Publication
First Author: Shima N
Year: 2004
Journal: Mol Cell Biol
Title: The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm.
Volume: 24
Issue: 23
Pages: 10381-9
Publication
First Author: Shima N
Year: 2003
Journal: Genetics
Title: Phenotype-based identification of mouse chromosome instability mutants.
Volume: 163
Issue: 3
Pages: 1031-40
Publication
First Author: Masuda K
Year: 2006
Journal: DNA Repair (Amst)
Title: Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes.
Volume: 5
Issue: 11
Pages: 1384-91
Publication
First Author: Mateos-Gomez PA
Year: 2015
Journal: Nature
Title: Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Volume: 518
Issue: 7538
Pages: 254-7
Publication
First Author: Schimmel J
Year: 2017
Journal: EMBO J
Title: Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.
Volume: 36
Issue: 24
Pages: 3634-3649
Publication
First Author: Yousefzadeh MJ
Year: 2014
Journal: PLoS Genet
Title: Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.
Volume: 10
Issue: 10
Pages: e1004654
Publication
First Author: Masuda K
Year: 2007
Journal: J Biol Chem
Title: DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.
Volume: 282
Issue: 24
Pages: 17387-94
Publication
First Author: Ceccaldi R
Year: 2015
Journal: Nature
Title: Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Volume: 518
Issue: 7538
Pages: 258-62
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Zan H
Year: 2005
Journal: EMBO J
Title: The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation.
Volume: 24
Issue: 21
Pages: 3757-69
Publication
First Author: Carvajal-Garcia J
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
Volume: 117
Issue: 15
Pages: 8476-8485
Publication
First Author: Mateos-Gomez PA
Year: 2017
Journal: Nat Struct Mol Biol
Title: The helicase domain of Polθ counteracts RPA to promote alt-NHEJ.
Volume: 24
Issue: 12
Pages: 1116-1123
Publication
First Author: Zelensky AN
Year: 2017
Journal: Nat Commun
Title: Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA.
Volume: 8
Issue: 1
Pages: 66
Publication
First Author: Ukai A
Year: 2006
Journal: Genes Cells
Title: Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells.
Volume: 11
Issue: 2
Pages: 111-21
Publication
First Author: Wyatt DW
Year: 2016
Journal: Mol Cell
Title: Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
Volume: 63
Issue: 4
Pages: 662-673
GXD Expression      
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Small Intestine
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: colon
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Sk. Muscle
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Lung
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3531215
Age: embryonic day 7.0
Specimen Label: Embryo 7d
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3531215
Age: embryonic day 11.0
Specimen Label: Embryo 11d
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3531215
Age: embryonic day 15.0
Specimen Label: Embryo 15d
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3531215
Age: embryonic day 17.0
Specimen Label: Embryo 17d
Detected: true
Specimen Num: 12
Publication
First Author: Marini F
Year: 2003
Journal: J Biol Chem
Title: POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308.
Volume: 278
Issue: 34
Pages: 32014-9
Publication
First Author: Masuda K
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.
Volume: 102
Issue: 39
Pages: 13986-91
Publication
First Author: Martomo SA
Year: 2008
Journal: DNA Repair (Amst)
Title: Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.
Volume: 7
Issue: 9
Pages: 1603-8
Publication
First Author: Takata KI
Year: 2017
Journal: PLoS Genet
Title: Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance.
Volume: 13
Issue: 6
Pages: e1006818
Publication
First Author: Vekariya U
Year: 2023
Journal: Blood
Title: DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Volume: 141
Issue: 19
Pages: 2372-2389
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Publication  
First Author: Smolinska A
Year: 2022
Journal: Cancers (Basel)
Title: DNA Polymerase Theta Plays a Critical Role in Pancreatic Cancer Development and Metastasis.
Volume: 14
Issue: 17
Publication  
First Author: Zan H
Year: 2017
Journal: Nat Commun
Title: Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination.
Volume: 8
Pages: 14244
Publication
First Author: Shah P
Year: 2024
Journal: Nat Commun
Title: Primordial germ cell DNA demethylation and development require DNA translesion synthesis.
Volume: 15
Issue: 1
Pages: 3734
Publication
First Author: Farini D
Year: 2020
Journal: Cell Rep
Title: A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.
Volume: 31
Issue: 9
Pages: 107703
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference