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Search results 1 to 100 out of 670 for Prdm16

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Hits by Strain

Type Details Score
Gene
63976 | PRDM16
Type: gene
Organism: human
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Gene
100485690 | prdm16
Type: gene
Organism: frog, western clawed
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Gene
479582 | PRDM16
Type: gene
Organism: dog, domestic
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Gene
457227 | PRDM16
Type: gene
Organism: chimpanzee
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Gene
100137803 | PRDM16
Type: gene
Organism: cattle
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Gene
100366024 | Prdm16
Type: gene
Organism: rat
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Gene
419388 | PRDM16
Type: gene
Organism: chicken
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Gene
796720 | prdm16
Type: gene
Organism: zebrafish
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Gene
100430112 | PRDM16
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1917923 | Prdm16
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
440556 | PRDM16-DT
Type: gene
Organism: human
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GXD Expression
GXD Expression
     
Probe: MGI:5312047
Assay Type: RT-PCR
Annotation Date: 2012-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:5312054
Age: embryonic day 15.0
Specimen Label: Prdm16 +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5312047
Assay Type: RT-PCR
Annotation Date: 2012-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:5312054
Age: embryonic day 15.0
Specimen Label: Prdm16 -/-
Detected: true
Specimen Num: 3
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Publication
18719582 | J:138823
First Author: Seale P
Year: 2008
Journal: Nature
Title: PRDM16 controls a brown fat/skeletal muscle switch.
Volume: 454
Issue: 7207
Pages: 961-7
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Publication
23768516 | J:206694
First Author: Arndt AK
Year: 2013
Journal: Am J Hum Genet
Title: Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.
Volume: 93
Issue: 1
Pages: 67-77
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Publication
21123942 | J:171857
First Author: Seale P
Year: 2011
Journal: J Clin Invest
Title: Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.
Volume: 121
Issue: 1
Pages: 96-105
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Publication
22939622 | J:269562
First Author: Pinheiro I
Year: 2012
Journal: Cell
Title: Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
Volume: 150
Issue: 5
Pages: 948-60
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Publication
19853285 | J:157305
First Author: Horn KH
Year: 2011
Journal: Acta Histochem
Title: PRDM16 expression in the developing mouse embryo.
Volume: 113
Issue: 2
Pages: 150-5
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Publication
37324380 | J:337130
 
First Author: Thompson M
Year: 2023
Journal: Front Physiol
Title: PRDM16 regulates arterial development and vascular integrity.
Volume: 14
Pages: 1165379
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Publication
21343612 | J:177801
First Author: Aguilo F
Year: 2011
Journal: Blood
Title: Prdm16 is a physiologic regulator of hematopoietic stem cells.
Volume: 117
Issue: 19
Pages: 5057-66
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Publication
35978186 | J:333058
First Author: Wang Q
Year: 2022
Journal: Nature
Title: Post-translational control of beige fat biogenesis by PRDM16 stabilization.
Volume: 609
Issue: 7925
Pages: 151-158
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Publication
29878897 | J:264335
First Author: Corrigan DJ
Year: 2018
Journal: J Clin Invest
Title: PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signature.
Volume: 128
Issue: 8
Pages: 3250-3264
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Publication
29539416 | J:260351
First Author: Chen Q
Year: 2018
Journal: Cell Rep
Title: Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis.
Volume: 22
Issue: 11
Pages: 2860-2872
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Publication
28698301 | J:244857
First Author: Shimada IS
Year: 2017
Journal: Genes Dev
Title: Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells.
Volume: 31
Issue: 11
Pages: 1134-1146
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Publication
35451126 | J:330213
First Author: Ebeid M
Year: 2022
Journal: Dev Dyn
Title: PRDM16 expression and function in mammalian cochlear development.
Volume: 251
Issue: 10
Pages: 1666-1683
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Publication
33597191 | J:303701
 
First Author: He L
Year: 2021
Journal: Development
Title: PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors.
Volume: 148
Issue: 6
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Publication
20007998 | J:157112
First Author: Bjork BC
Year: 2010
Journal: Hum Mol Genet
Title: Prdm16 is required for normal palatogenesis in mice.
Volume: 19
Issue: 5
Pages: 774-89
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Publication
37079380 | J:355429
 
First Author: Wang Z
Year: 2023
Journal: JCI Insight
Title: PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm.
Volume: 8
Issue: 11
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Publication
22405074 | J:182670
First Author: Ohno H
Year: 2012
Journal: Cell Metab
Title: PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.
Volume: 15
Issue: 3
Pages: 395-404
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Publication
31564549 | J:286473
First Author: Stine RR
Year: 2019
Journal: Cell Stem Cell
Title: PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism.
Volume: 25
Issue: 6
Pages: 830-845.e8
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Publication
23473036 | J:198134
First Author: Villanueva CJ
Year: 2013
Journal: Cell Metab
Title: Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs.
Volume: 17
Issue: 3
Pages: 423-35
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Publication
20835244 | J:244934
First Author: Chuikov S
Year: 2010
Journal: Nat Cell Biol
Title: Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress.
Volume: 12
Issue: 10
Pages: 999-1006
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Publication
38239368 | J:348757
 
First Author: Nah J
Year: 2023
Journal: Front Immunol
Title: PRDM16 regulates γδT17 cell differentiation via controlling type 17 program and lipid-dependent cell fitness.
Volume: 14
Pages: 1332386
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Publication
25644604 | J:218231
First Author: Harms MJ
Year: 2015
Journal: Genes Dev
Title: PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.
Volume: 29
Issue: 3
Pages: 298-307
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Publication
24196706 | J:207678
First Author: Ohno H
Year: 2013
Journal: Nature
Title: EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex.
Volume: 504
Issue: 7478
Pages: 163-7
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Publication
37842925 | J:349286
First Author: Kühnisch J
Year: 2024
Journal: Cardiovasc Res
Title: Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.
Volume: 119
Issue: 18
Pages: 2902-2916
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Publication
33086060 | J:298888
First Author: Cibi DM
Year: 2020
Journal: Cell Rep
Title: Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure.
Volume: 33
Issue: 3
Pages: 108288
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Publication
24439384 | J:208683
First Author: Cohen P
Year: 2014
Journal: Cell
Title: Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.
Volume: 156
Issue: 1-2
Pages: 304-16
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Publication
36828547 | J:333940
 
First Author: Hurwitz E
Year: 2023
Journal: J Cell Biol
Title: Antagonism between Prdm16 and Smad4 specifies the trajectory and progression of pancreatic cancer.
Volume: 222
Issue: 4
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Publication
27641099 | J:251930
First Author: Yang Q
Year: 2016
Journal: Cell Metab
Title: AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis.
Volume: 24
Issue: 4
Pages: 542-554
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Publication
28408438 | J:243350
First Author: Kissig M
Year: 2017
Journal: EMBO J
Title: PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.
Volume: 36
Issue: 11
Pages: 1528-1542
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Publication
17618855 | J:129891
First Author: Seale P
Year: 2007
Journal: Cell Metab
Title: Transcriptional control of brown fat determination by PRDM16.
Volume: 6
Issue: 1
Pages: 38-54
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Publication
39304345 | J:354224
 
First Author: Van Wauwe J
Year: 2024
Journal: Life Sci Alliance
Title: PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates.
Volume: 7
Issue: 12
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Publication
27993981 | J:239166
First Author: Inoue M
Year: 2017
Journal: Development
Title: Prdm16 is crucial for progression of the multipolar phase during neural differentiation of the developing neocortex.
Volume: 144
Issue: 3
Pages: 385-399
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Publication
24703692 | J:213153
First Author: Harms MJ
Year: 2014
Journal: Cell Metab
Title: Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.
Volume: 19
Issue: 4
Pages: 593-604
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Publication
25071153 | J:224343
First Author: Jin Q
Year: 2014
Journal: Mol Cell Biol
Title: Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis.
Volume: 34
Issue: 19
Pages: 3746-53
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Publication
33060132 | J:300505
 
First Author: Turrero García M
Year: 2020
Journal: Development
Title: Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production.
Volume: 147
Issue: 22
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Publication
25644605 | J:218230
First Author: Iida S
Year: 2015
Journal: Genes Dev
Title: PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1.
Volume: 29
Issue: 3
Pages: 308-21
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Publication
32044379 | J:288308
First Author: Shull LC
Year: 2020
Journal: Dev Biol
Title: The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development.
Volume: 461
Issue: 2
Pages: 132-144
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Publication
22859371 | J:193353
First Author: Borensztein M
Year: 2012
Journal: FASEB J
Title: Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression.
Volume: 26
Issue: 11
Pages: 4584-91
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Publication
29053761 | J:254641
First Author: Groman-Lupa S
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina.
Volume: 58
Issue: 12
Pages: 5421-5433
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Publication
37433344 | J:341052
 
First Author: Hu T
Year: 2023
Journal: Metabolism
Title: PRDM16 exerts critical role in myocardial metabolism and energetics in type 2 diabetes induced cardiomyopathy.
Volume: 146
Pages: 155658
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Publication
30327195 | J:318872
First Author: Chi YL
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Res
Title: RBM4a modulates the impact of PRDM16 on development of brown adipocytes through an alternative splicing mechanism.
Volume: 1865
Issue: 11 Pt A
Pages: 1515-1525
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Publication
34915728 | J:326525
First Author: Wu T
Year: 2022
Journal: Circulation
Title: PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle.
Volume: 145
Issue: 8
Pages: 586-602
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Publication
12816872 | J:86428
First Author: Nishikata I
Year: 2003
Journal: Blood
Title: A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation.
Volume: 102
Issue: 9
Pages: 3323-32
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Publication
28424158 | J:242985
First Author: Strassman A
Year: 2017
Journal: Dis Model Mech
Title: Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping.
Volume: 10
Issue: 7
Pages: 909-922
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Publication
32437910 | J:297208
 
First Author: McGlynn KA
Year: 2020
Journal: Exp Hematol
Title: Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential.
Volume: 85
Pages: 20-32.e3
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Publication
17467076 | J:122807
First Author: Warner DR
Year: 2007
Journal: Biochim Biophys Acta
Title: PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.
Volume: 1773
Issue: 6
Pages: 814-20
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Publication
33268499 | J:299741
First Author: Gudmundsson KO
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence.
Volume: 117
Issue: 50
Pages: 31945-31953
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Publication
32083975 | J:291042
First Author: Nam JM
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac-specific inactivation of Prdm16 effects cardiac conduction abnormalities and cardiomyopathy-associated phenotypes.
Volume: 318
Issue: 4
Pages: H764-H777
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Publication
19641492 | J:152000
First Author: Kajimura S
Year: 2009
Journal: Nature
Title: Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.
Volume: 460
Issue: 7259
Pages: 1154-8
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Publication
18483224 | J:153416
First Author: Kajimura S
Year: 2008
Journal: Genes Dev
Title: Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.
Volume: 22
Issue: 10
Pages: 1397-409
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ncRNA Gene
MGI:3651882 | Prdm16os
Type: antisense_lncRNA_gene
Organism: mouse, laboratory
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Publication
29320703 | J:256863
First Author: Chi J
Year: 2018
Journal: Cell Metab
Title: Three-Dimensional Adipose Tissue Imaging Reveals Regional Variation in Beige Fat Biogenesis and PRDM16-Dependent Sympathetic Neurite Density.
Volume: 27
Issue: 1
Pages: 226-236.e3
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Publication
29320702 | J:256864
First Author: Hasegawa Y
Year: 2018
Journal: Cell Metab
Title: Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.
Volume: 27
Issue: 1
Pages: 180-194.e6
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Publication
31155495 | J:352070
First Author: Wang W
Year: 2019
Journal: Cell Metab
Title: A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate.
Volume: 30
Issue: 1
Pages: 174-189.e5
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HT Experiment
E-GEOD-55080 | Prdm16 Knockout Brown Adipose Tissue
Series Id: GSE55080
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
33591269 | J:316947
   
First Author: Chi J
Year: 2021
Journal: Elife
Title: Early postnatal interactions between beige adipocytes and sympathetic neurites regulate innervation of subcutaneous fat.
Volume: 10
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Publication
37058410 | J:335241
First Author: Nigro P
Year: 2023
Journal: Cell Rep
Title: Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix.
Volume: 42
Issue: 4
Pages: 112392
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Publication
30893596 | J:281443
First Author: Nakatsu Y
Year: 2019
Journal: Cell Rep
Title: Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.
Volume: 26
Issue: 12
Pages: 3221-3230.e3
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Publication
34078594 | J:317326
 
First Author: Biferali B
Year: 2021
Journal: Sci Adv
Title: Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair.
Volume: 7
Issue: 23
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Publication
29019320 | J:248317
   
First Author: Jiang Y
Year: 2017
Journal: Elife
Title: Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation.
Volume: 6
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UniProt Feature
UniProt Feature
Begin: 1
Description: Histone-lysine N-methyltransferase PRDM16
Type: chain
End: 1275
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Publication
33220490 | J:335828
 
First Author: Marchildon F
Year: 2021
Journal: Mol Metab
Title: Beige fat is dispensable for the metabolic benefits associated with myostatin deletion.
Volume: 43
Pages: 101120
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Publication
16109773 | J:124368
First Author: Du Y
Year: 2005
Journal: Blood
Title: Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells.
Volume: 106
Issue: 12
Pages: 3932-9
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Publication
23143398 | J:195252
First Author: Trajkovski M
Year: 2012
Journal: Nat Cell Biol
Title: MyomiR-133 regulates brown fat differentiation through Prdm16.
Volume: 14
Issue: 12
Pages: 1330-5
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Publication
28701693 | J:248940
First Author: Huang L
Year: 2017
Journal: Nat Commun
Title: Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation.
Volume: 8
Issue: 1
Pages: 68
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Publication
26789249 | J:229092
First Author: Luchsinger LL
Year: 2016
Journal: Nature
Title: Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential.
Volume: 529
Issue: 7587
Pages: 528-31
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Publication
35132438 | J:321981
 
First Author: Shull LC
Year: 2022
Journal: Development
Title: PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation.
Volume: 149
Issue: 4
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Publication
32041791 | J:291489
 
First Author: Chui A
Year: 2020
Journal: Development
Title: Oxidative stress regulates progenitor behavior and cortical neurogenesis.
Volume: 147
Issue: 5
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Publication
28988768 | J:248914
First Author: Chen Y
Year: 2017
Journal: Cell
Title: Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity.
Volume: 171
Issue: 4
Pages: 836-848.e13
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Publication
22033933 | J:178692
First Author: Hondares E
Year: 2011
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.
Volume: 286
Issue: 50
Pages: 43112-22
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Publication
29779941 | J:269647
First Author: Baizabal JM
Year: 2018
Journal: Neuron
Title: The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.
Volume: 98
Issue: 5
Pages: 945-962.e8
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Publication
39284798 | J:354192
First Author: He H
Year: 2024
Journal: Nat Commun
Title: PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function.
Volume: 15
Issue: 1
Pages: 8112
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Publication
23852729 | J:198781
First Author: Sugiyama T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.
Volume: 110
Issue: 31
Pages: 12691-6
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Publication
21967974 | J:179097
First Author: Avagyan S
Year: 2011
Journal: Blood
Title: Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis.
Volume: 118
Issue: 23
Pages: 6078-86
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Publication
36906847 | J:339780
First Author: Nishimura H
Year: 2023
Journal: Genes Cells
Title: Maternal epigenetic factors in embryonic and postnatal development.
Volume: 28
Issue: 6
Pages: 422-432
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Publication
23149718 | J:321350
First Author: Warner DR
Year: 2013
Journal: Cell Tissue Res
Title: Gene expression changes in the secondary palate and mandible of Prdm16(-/-) mice.
Volume: 351
Issue: 3
Pages: 445-52
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Publication
30352954 | J:269323
First Author: Vázquez P
Year: 2018
Journal: J Lipid Res
Title: Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation.
Volume: 59
Issue: 12
Pages: 2308-2320
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Publication
26963625 | J:232408
First Author: Van De Pette M
Year: 2016
Journal: PLoS Genet
Title: Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.
Volume: 12
Issue: 3
Pages: e1005916
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Publication
19050759 | J:144373
First Author: Kinameri E
Year: 2008
Journal: PLoS One
Title: Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.
Volume: 3
Issue: 12
Pages: e3859
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Protein Coding Gene
MGP_CAROLIEiJ_G0026872 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029196 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029161 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0029109 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0029177 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0028898 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1917923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0029626 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0028311 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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