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Search results 1 to 100 out of 544 for Prdm16

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
GXD Expression      
Probe: MGI:5312047
Assay Type: RT-PCR
Annotation Date: 2012-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:5312054
Age: embryonic day 15.0
Specimen Label: Prdm16 +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5312047
Assay Type: RT-PCR
Annotation Date: 2012-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:5312054
Age: embryonic day 15.0
Specimen Label: Prdm16 -/-
Detected: true
Specimen Num: 3
Publication
First Author: Seale P
Year: 2008
Journal: Nature
Title: PRDM16 controls a brown fat/skeletal muscle switch.
Volume: 454
Issue: 7207
Pages: 961-7
Publication
First Author: Arndt AK
Year: 2013
Journal: Am J Hum Genet
Title: Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.
Volume: 93
Issue: 1
Pages: 67-77
Publication
First Author: Seale P
Year: 2011
Journal: J Clin Invest
Title: Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.
Volume: 121
Issue: 1
Pages: 96-105
Publication
First Author: Pinheiro I
Year: 2012
Journal: Cell
Title: Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.
Volume: 150
Issue: 5
Pages: 948-60
Publication
First Author: Horn KH
Year: 2011
Journal: Acta Histochem
Title: PRDM16 expression in the developing mouse embryo.
Volume: 113
Issue: 2
Pages: 150-5
Publication
First Author: Aguilo F
Year: 2011
Journal: Blood
Title: Prdm16 is a physiologic regulator of hematopoietic stem cells.
Volume: 117
Issue: 19
Pages: 5057-66
Publication
First Author: Corrigan DJ
Year: 2018
Journal: J Clin Invest
Title: PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signature.
Volume: 128
Issue: 8
Pages: 3250-3264
Publication
First Author: Chen Q
Year: 2018
Journal: Cell Rep
Title: Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis.
Volume: 22
Issue: 11
Pages: 2860-2872
Publication
First Author: Shimada IS
Year: 2017
Journal: Genes Dev
Title: Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells.
Volume: 31
Issue: 11
Pages: 1134-1146
Publication
First Author: Bjork BC
Year: 2010
Journal: Hum Mol Genet
Title: Prdm16 is required for normal palatogenesis in mice.
Volume: 19
Issue: 5
Pages: 774-89
Publication
First Author: Stine RR
Year: 2019
Journal: Cell Stem Cell
Title: PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism.
Volume: 25
Issue: 6
Pages: 830-845.e8
Publication
First Author: Ohno H
Year: 2012
Journal: Cell Metab
Title: PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.
Volume: 15
Issue: 3
Pages: 395-404
Allele
Name: PR domain containing 16; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Inducible, Recombinase, Reporter
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Allele
Name: PR domain containing 16; targeted mutation 1.1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Inducible, Recombinase, Reporter
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Publication  
First Author: He L
Year: 2021
Journal: Development
Title: PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors.
Volume: 148
Issue: 6
Publication
First Author: Villanueva CJ
Year: 2013
Journal: Cell Metab
Title: Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs.
Volume: 17
Issue: 3
Pages: 423-35
Publication
First Author: Chuikov S
Year: 2010
Journal: Nat Cell Biol
Title: Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress.
Volume: 12
Issue: 10
Pages: 999-1006
Publication
First Author: Cohen P
Year: 2014
Journal: Cell
Title: Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.
Volume: 156
Issue: 1-2
Pages: 304-16
Publication
First Author: Harms MJ
Year: 2015
Journal: Genes Dev
Title: PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.
Volume: 29
Issue: 3
Pages: 298-307
Publication
First Author: Ohno H
Year: 2013
Journal: Nature
Title: EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex.
Volume: 504
Issue: 7478
Pages: 163-7
Publication
First Author: Yang Q
Year: 2016
Journal: Cell Metab
Title: AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis.
Volume: 24
Issue: 4
Pages: 542-554
Publication
First Author: Cibi DM
Year: 2020
Journal: Cell Rep
Title: Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure.
Volume: 33
Issue: 3
Pages: 108288
Publication
First Author: Kissig M
Year: 2017
Journal: EMBO J
Title: PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.
Volume: 36
Issue: 11
Pages: 1528-1542
Publication
First Author: Seale P
Year: 2007
Journal: Cell Metab
Title: Transcriptional control of brown fat determination by PRDM16.
Volume: 6
Issue: 1
Pages: 38-54
Publication
First Author: Inoue M
Year: 2017
Journal: Development
Title: Prdm16 is crucial for progression of the multipolar phase during neural differentiation of the developing neocortex.
Volume: 144
Issue: 3
Pages: 385-399
Publication
First Author: Harms MJ
Year: 2014
Journal: Cell Metab
Title: Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.
Volume: 19
Issue: 4
Pages: 593-604
Publication
First Author: Jin Q
Year: 2014
Journal: Mol Cell Biol
Title: Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis.
Volume: 34
Issue: 19
Pages: 3746-53
Publication  
First Author: Turrero García M
Year: 2020
Journal: Development
Title: Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production.
Volume: 147
Issue: 22
Publication
First Author: Iida S
Year: 2015
Journal: Genes Dev
Title: PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1.
Volume: 29
Issue: 3
Pages: 308-21
Publication
First Author: Shull LC
Year: 2020
Journal: Dev Biol
Title: The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development.
Volume: 461
Issue: 2
Pages: 132-144
Publication
First Author: Groman-Lupa S
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina.
Volume: 58
Issue: 12
Pages: 5421-5433
Publication
First Author: Borensztein M
Year: 2012
Journal: FASEB J
Title: Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression.
Volume: 26
Issue: 11
Pages: 4584-91
Publication
First Author: Chi YL
Year: 2018
Journal: Biochim Biophys Acta Mol Cell Res
Title: RBM4a modulates the impact of PRDM16 on development of brown adipocytes through an alternative splicing mechanism.
Volume: 1865
Issue: 11 Pt A
Pages: 1515-1525
Publication
First Author: Wu T
Year: 2022
Journal: Circulation
Title: PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle.
Volume: 145
Issue: 8
Pages: 586-602
Publication
First Author: Nishikata I
Year: 2003
Journal: Blood
Title: A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation.
Volume: 102
Issue: 9
Pages: 3323-32
Publication  
First Author: McGlynn KA
Year: 2020
Journal: Exp Hematol
Title: Prdm3 and Prdm16 cooperatively maintain hematopoiesis and clonogenic potential.
Volume: 85
Pages: 20-32.e3
Publication
First Author: Strassman A
Year: 2017
Journal: Dis Model Mech
Title: Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping.
Volume: 10
Issue: 7
Pages: 909-922
Publication
First Author: Gudmundsson KO
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Prdm16 is a critical regulator of adult long-term hematopoietic stem cell quiescence.
Volume: 117
Issue: 50
Pages: 31945-31953
Publication
First Author: Warner DR
Year: 2007
Journal: Biochim Biophys Acta
Title: PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.
Volume: 1773
Issue: 6
Pages: 814-20
Publication
First Author: Nam JM
Year: 2020
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac-specific inactivation of Prdm16 effects cardiac conduction abnormalities and cardiomyopathy-associated phenotypes.
Volume: 318
Issue: 4
Pages: H764-H777
Publication
First Author: Kajimura S
Year: 2009
Journal: Nature
Title: Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.
Volume: 460
Issue: 7259
Pages: 1154-8
Publication
First Author: Kajimura S
Year: 2008
Journal: Genes Dev
Title: Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.
Volume: 22
Issue: 10
Pages: 1397-409
HT Experiment
Series Id: GSE55080
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Chi J
Year: 2018
Journal: Cell Metab
Title: Three-Dimensional Adipose Tissue Imaging Reveals Regional Variation in Beige Fat Biogenesis and PRDM16-Dependent Sympathetic Neurite Density.
Volume: 27
Issue: 1
Pages: 226-236.e3
ncRNA Gene
Type: antisense_lncRNA_gene
Organism: Mus musculus
Publication
First Author: Hasegawa Y
Year: 2018
Journal: Cell Metab
Title: Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.
Volume: 27
Issue: 1
Pages: 180-194.e6
Publication    
First Author: Chi J
Year: 2021
Journal: Elife
Title: Early postnatal interactions between beige adipocytes and sympathetic neurites regulate innervation of subcutaneous fat.
Volume: 10
Publication
First Author: Nakatsu Y
Year: 2019
Journal: Cell Rep
Title: Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.
Volume: 26
Issue: 12
Pages: 3221-3230.e3
Publication  
First Author: Biferali B
Year: 2021
Journal: Sci Adv
Title: Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair.
Volume: 7
Issue: 23
Publication    
First Author: Jiang Y
Year: 2017
Journal: Elife
Title: Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation.
Volume: 6
Publication
First Author: Luchsinger LL
Year: 2016
Journal: Nature
Title: Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential.
Volume: 529
Issue: 7587
Pages: 528-31
Publication
First Author: Du Y
Year: 2005
Journal: Blood
Title: Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells.
Volume: 106
Issue: 12
Pages: 3932-9
Publication
First Author: Trajkovski M
Year: 2012
Journal: Nat Cell Biol
Title: MyomiR-133 regulates brown fat differentiation through Prdm16.
Volume: 14
Issue: 12
Pages: 1330-5
Publication
First Author: Huang L
Year: 2017
Journal: Nat Commun
Title: Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation.
Volume: 8
Issue: 1
Pages: 68
Publication  
First Author: Shull LC
Year: 2022
Journal: Development
Title: PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation.
Volume: 149
Issue: 4
Publication  
First Author: Chui A
Year: 2020
Journal: Development
Title: Oxidative stress regulates progenitor behavior and cortical neurogenesis.
Volume: 147
Issue: 5
Publication
First Author: Chen Y
Year: 2017
Journal: Cell
Title: Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity.
Volume: 171
Issue: 4
Pages: 836-848.e13
Publication
First Author: Baizabal JM
Year: 2018
Journal: Neuron
Title: The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.
Volume: 98
Issue: 5
Pages: 945-962.e8
Publication
First Author: Hondares E
Year: 2011
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.
Volume: 286
Issue: 50
Pages: 43112-22
Publication
First Author: Sugiyama T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.
Volume: 110
Issue: 31
Pages: 12691-6
Publication
First Author: Avagyan S
Year: 2011
Journal: Blood
Title: Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis.
Volume: 118
Issue: 23
Pages: 6078-86
UniProt Feature
Begin: 1
Description: Histone-lysine N-methyltransferase PRDM16
Type: chain
End: 1275
Publication
First Author: Warner DR
Year: 2013
Journal: Cell Tissue Res
Title: Gene expression changes in the secondary palate and mandible of Prdm16(-/-) mice.
Volume: 351
Issue: 3
Pages: 445-52
Publication
First Author: Vázquez P
Year: 2018
Journal: J Lipid Res
Title: Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation.
Volume: 59
Issue: 12
Pages: 2308-2320
Publication
First Author: Van De Pette M
Year: 2016
Journal: PLoS Genet
Title: Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.
Volume: 12
Issue: 3
Pages: e1005916
Publication
First Author: Kinameri E
Year: 2008
Journal: PLoS One
Title: Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis.
Volume: 3
Issue: 12
Pages: e3859
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kaneda-Nakashima K
Year: 2022
Journal: Exp Cell Res
Title: Role of Mel1/Prdm16 in bone differentiation and morphology.
Volume: 410
Issue: 2
Pages: 112969
Publication  
First Author: Ding H
Year: 2016
Journal: Nat Commun
Title: Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16.
Volume: 7
Pages: 11533
GXD Expression      
Probe: MGI:5807408
Assay Type: Northern blot
Annotation Date: 2016-11-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:5807410
Age: embryonic day 14.5
Specimen Label: limb bud
Detected: true
Specimen Num: 4