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Search results 1 to 100 out of 122 for Prdm2

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Type Details Score
Gene
7799 | PRDM2
Type: gene
Organism: human
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Gene
100170624 | prdm2
Type: gene
Organism: frog, western clawed
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Gene
313678 | Prdm2
Type: gene
Organism: rat
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Gene
469125 | PRDM2
Type: gene
Organism: chimpanzee
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Gene
789222 | PRDM2
Type: gene
Organism: cattle
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Gene
100688431 | PRDM2
Type: gene
Organism: dog, domestic
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Gene
419478 | PRDM2
Type: gene
Organism: chicken
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Gene
716295 | PRDM2
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR009170 | PRDM2
Type: Family
Description: PRDM2 (also known as RIZ) is a transcriptional regulator and tumour suppressor that catalyzes methylation of lysine 9 of histone H3. Its PR domain is responsible for its catalytic activity []. PRDM2 belongs to the PRDM family, whose members are characterised by the presence of an N-terminal PR (PRDI-BF1 and RIZ1 homology) domain followed by multiple zinc fingers which confer DNA binding activity. PR domains are only distantly related to the classical SET methyltransferase domains []. PRDM2 interacts with another tumour suppressor, the retinoblastoma protein (Rb). A short motif, IRCDE, in the acidic region (AR) of RIZ is important for this interaction [].
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Protein Coding Gene
MGI:107628 | Prdm2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
B9EKQ3
Organism: Mus musculus/domesticus
Length: 1670  
Fragment?: false
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Publication
25640033 | -
First Author: Sun Y
Year: 2015
Journal: Biochemistry
Title: Structural and functional characterization of the acidic region from the RIZ tumor suppressor.
Volume: 54
Issue: 6
Pages: 1390-400
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Publication
18082620 | -
First Author: Briknarová K
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Structural studies of the SET domain from RIZ1 tumor suppressor.
Volume: 366
Issue: 3
Pages: 807-13
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Protein
A2A7B5
Organism: Mus musculus/domesticus
Length: 1709  
Fragment?: false
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Publication
24095733 | J:277873
First Author: Wu H
Year: 2013
Journal: Cell Rep
Title: Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9.
Volume: 5
Issue: 1
Pages: 13-20
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Publication
25812847 | J:320688
First Author: Wada S
Year: 2015
Journal: Histochem Cell Biol
Title: H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro.
Volume: 144
Issue: 1
Pages: 13-20
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Publication
23333759 | J:194983
First Author: Ideno H
Year: 2013
Journal: Gene Expr Patterns
Title: Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development.
Volume: 13
Issue: 3-4
Pages: 84-90
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Protein Coding Gene
MGP_CAROLIEiJ_G0026760 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029065 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029025 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029049 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028763 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_107628 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029490 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028195 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028727 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028877 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028844 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028976 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029528 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028273 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029092 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027740 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
26709097 | J:295457
First Author: Xie X
Year: 2016
Journal: Obesity (Silver Spring)
Title: Tumor suppressor RIZ1 in obesity and the PI3K/AKT/mTOR pathway.
Volume: 24
Issue: 2
Pages: 389-97
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Publication
15282304 | J:92242
First Author: Carling T
Year: 2004
Journal: Mol Cell Biol
Title: A histone methyltransferase is required for maximal response to female sex hormones.
Volume: 24
Issue: 16
Pages: 7032-42
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Publication
20557878 | J:163786
First Author: Noman AS
Year: 2010
Journal: Cell Immunol
Title: Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation.
Volume: 264
Issue: 2
Pages: 114-8
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GXD Expression
GXD Expression
   
Probe: MGI:6194851
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194882
Age: embryonic day 16.5
Image: 4
Specimen Label: a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6194851
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194882
Age: embryonic day 16.5
Image: 4
Specimen Label: b
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6194851
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194882
Age: embryonic day 16.5
Image: 4
Specimen Label: c
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6194851
Assay Type: RT-PCR
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Stage: TS24
Assay Id: MGI:6194882
Age: embryonic day 16.5
Image: 4
Specimen Label: d
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6194780
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6194863
Age: embryonic day 14.5
Image: 2D
Note: Very weak expression was detected in proliferating chondrocytes. A significant increase in expression was observed in the prehypertrophic and hypertrophic chondrocytes.
Specimen Label: 2D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6194780
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3262520
Stage: TS20
Assay Id: MGI:6194863
Age: embryonic day 12.5
Image: 1D
Specimen Label: 1D
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6194780
Assay Type: Immunohistochemistry
Annotation Date: 2018-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3535024
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6194863
Age: embryonic day 16.5
Image: 3D
Note: Expression was detected in the prehypertrophic and hypertrophic chondrocytes and the trabecular bones.
Specimen Label: 3D
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1869223
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1832123
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12400
Specimen Label: GUDMAP:12400
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5001744
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542298
Age: embryonic day 15.5
Image: GUDMAP:12399
Specimen Label: GUDMAP:12399
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6888188
Assay Type: RNA in situ
Annotation Date: 2022-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6888193
Age: embryonic day 16.5
Note: Expression in cells overlapping with or adjacent to Tnmd-positive tendon cells
Specimen Label: 2G
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6888188
Assay Type: RNA in situ
Annotation Date: 2022-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585424
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6888193
Age: embryonic day 16.5
Note: Expression in cells overlapping with or adjacent to Tnmd-positive tendon cells
Specimen Label: 2H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6888188
Assay Type: RNA in situ
Annotation Date: 2022-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6888193
Age: embryonic day 18.5
Note: Expression in cells overlapping with or adjacent to Tnmd-positive tendon cells
Specimen Label: S3G
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6888188
Assay Type: RNA in situ
Annotation Date: 2022-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6888193
Age: embryonic day 18.5
Note: Expression in cells overlapping with or adjacent to Tnmd-positive tendon cells
Specimen Label: S3H
Detected: true
Specimen Num: 4
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Publication
18852888 | J:295933
First Author: Zhou W
Year: 2008
Journal: PLoS One
Title: Requirement of RIZ1 for cancer prevention by methyl-balanced diet.
Volume: 3
Issue: 10
Pages: e3390
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Publication
7538672 | J:40271
First Author: Buyse IM
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.
Volume: 92
Issue: 10
Pages: 4467-71
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Publication
11544182 | J:71406
First Author: Steele-Perkins G
Year: 2001
Journal: Genes Dev
Title: Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily.
Volume: 15
Issue: 17
Pages: 2250-62
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Publication
8679000 | J:34782
First Author: Mock BA
Year: 1996
Journal: Mamm Genome
Title: Riz maps to distal chromosome 4 near genes involved in tumorigenesis and nerve degeneration.
Volume: 7
Issue: 8
Pages: 637
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Publication
18022353 | J:126799
First Author: Allis CD
Year: 2007
Journal: Cell
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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