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Search results 1 to 100 out of 1251 for Prkdc

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0.046s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: hamster, Chinese
Gene
Type: gene
Organism: horse
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Fabre KM
Year: 2011
Journal: Radiat Res
Title: Murine Prkdc polymorphisms impact DNA-PKcs function.
Volume: 175
Issue: 4
Pages: 493-500
Publication      
First Author: Peng SY
Year: 2018
Journal: MGI Direct Data Submission
Title: Direct data submission for Prkdc allele.
Publication
First Author: Faiola B
Year: 2003
Journal: Toxicol Sci
Title: Variations in Prkdc and susceptibility to benzene-induced toxicity in mice.
Volume: 75
Issue: 2
Pages: 321-32
Publication
First Author: Papeta N
Year: 2010
Journal: J Clin Invest
Title: Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice.
Volume: 120
Issue: 11
Pages: 4055-64
Publication
First Author: Oliveira CF
Year: 2020
Journal: Cell Tissue Res
Title: Foxn1 and Prkdc genes are important for testis function: evidence from nude and scid adult mice.
Volume: 380
Issue: 3
Pages: 615-625
Publication
First Author: Blackburn AC
Year: 2003
Journal: Cancer Res
Title: BALB/c alleles for Prkdc and Cdkn2a interact to modify tumor susceptibility in Trp53+/- mice.
Volume: 63
Issue: 10
Pages: 2364-8
Publication
First Author: Mori N
Year: 2001
Journal: Oncogene
Title: Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis.
Volume: 20
Issue: 28
Pages: 3609-19
Publication  
First Author: Watanabe M
Year: 2021
Journal: Biochem Biophys Res Commun
Title: A single amino acid substitution in PRKDC is a determinant of sensitivity to Adriamycin-induced renal injury in mouse.
Volume: 556
Pages: 121-126
Publication
First Author: Gurley KE
Year: 2017
Journal: Cell Death Differ
Title: Synergy between Prkdc and Trp53 regulates stem cell proliferation and GI-ARS after irradiation.
Volume: 24
Issue: 11
Pages: 1853-1860
Publication
First Author: Yu Y
Year: 2001
Journal: Cancer Res
Title: Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene.
Volume: 61
Issue: 5
Pages: 1820-4
Allele
Name: protein kinase, DNA activated, catalytic polypeptide; endonuclease-mediated mutation 5, Cathy Lutz
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Jhappan C
Year: 1997
Journal: Nat Genet
Title: DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus.
Volume: 17
Issue: 4
Pages: 483-6
Publication      
First Author: Beutler B
Year: 2001
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2011/12/20
Publication
First Author: Jhappan C
Year: 2000
Journal: Mol Cell Biol
Title: The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase.
Volume: 20
Issue: 11
Pages: 4075-83
Publication
First Author: Wang C
Year: 1999
Journal: J Immunol
Title: Irradiation-induced rescue of thymocyte differentiation and V(D)J recombination in mice lacking the catalytic subunit of DNA-dependent protein kinase.
Volume: 163
Issue: 11
Pages: 6065-71
Publication
First Author: Bogue MA
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation.
Volume: 95
Issue: 26
Pages: 15559-64
Publication      
First Author: Choi JH
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for screamer2
Publication
First Author: Sung YH
Year: 2014
Journal: Genome Res
Title: Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases.
Volume: 24
Issue: 1
Pages: 125-31
Publication
First Author: Sun X
Year: 2020
Journal: Nat Commun
Title: DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity.
Volume: 11
Issue: 1
Pages: 6182
Publication  
First Author: Takagi Y
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Characterization of novel, severely immunodeficient Prkdc(Δex57/Δex57) mice.
Volume: 678
Pages: 193-199
Publication      
First Author: Charles River
Year: 2017
Journal: Scientific info. sheet (http://www.criver.com/files/pdfs/rms/ncg/ncg-mouse-scientific--sheet.aspx)
Title: NOD CRISPR Prkdcil2r Gamma (NCG) Triple-Immunodeficient Mouse Model
Publication  
First Author: Liu J
Year: 2009
Journal: Brain Res
Title: The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.
Volume: 1296
Pages: 164-75
Publication
First Author: Gladdy RA
Year: 2006
Journal: Mol Cancer Res
Title: p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.
Volume: 4
Issue: 5
Pages: 311-8
Publication
First Author: Lund J
Year: 1999
Journal: Mamm Genome
Title: Sequence-ready physical map of the mouse chromosome 16 region with conserved synteny to the human velocardiofacial syndrome region on 22q11.2.
Volume: 10
Issue: 5
Pages: 438-43
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Zheng Z
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse.
Volume: 102
Issue: 7
Pages: 2502-7
Publication
First Author: Araki R
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice.
Volume: 94
Issue: 6
Pages: 2438-43
Publication
First Author: Fujimori A
Year: 1997
Journal: Genomics
Title: The murine DNA-PKcs gene consists of 86 exons dispersed in more than 250 kb.
Volume: 45
Issue: 1
Pages: 194-9
Publication
First Author: Hamatani K
Year: 1996
Journal: Immunogenetics
Title: Cloning and chromosomal mapping of the mouse DNA-dependent protein kinase gene.
Volume: 45
Issue: 1
Pages: 1-5
Publication
First Author: Blunt T
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.
Volume: 93
Issue: 19
Pages: 10285-90
Publication
First Author: Danska JS
Year: 1996
Journal: Mol Cell Biol
Title: Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.
Volume: 16
Issue: 10
Pages: 5507-17
Publication
First Author: Espejel S
Year: 2002
Journal: EMBO J
Title: Functional interaction between DNA-PKcs and telomerase in telomere length maintenance.
Volume: 21
Issue: 22
Pages: 6275-87
Publication
First Author: Mangada J
Year: 2009
Journal: Diabetes
Title: Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.
Volume: 58
Issue: 1
Pages: 165-73
Publication
First Author: Matsuoka K
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout.
Volume: 436
Issue: 3
Pages: 400-5
Publication
First Author: Butler JM
Year: 2010
Journal: Cell Stem Cell
Title: Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
Volume: 6
Issue: 3
Pages: 251-64
Publication
First Author: Martin AJ
Year: 2016
Journal: JCI Insight
Title: Anti-coreceptor therapy drives selective T cell egress by suppressing inflammation-dependent chemotactic cues.
Volume: 1
Issue: 17
Pages: e87636
Publication
First Author: Mamalaki C
Year: 1993
Journal: Dev Immunol
Title: Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen.
Volume: 3
Issue: 3
Pages: 159-74
Publication
First Author: O'Reilly LA
Year: 1997
Journal: Int Immunol
Title: bcl-2 transgene expression promotes survival and reduces proliferation of CD3-CD4-CD8- T cell progenitors.
Volume: 9
Issue: 9
Pages: 1291-301
Publication
First Author: Barthold SW
Year: 2006
Journal: Infect Immun
Title: Antibody-mediated disease remission in the mouse model of lyme borreliosis.
Volume: 74
Issue: 8
Pages: 4817-25
Publication
First Author: Mishra R
Year: 2010
Journal: PLoS Pathog
Title: NK cells and gammadelta T cells mediate resistance to polyomavirus-induced tumors.
Volume: 6
Issue: 5
Pages: e1000924
Publication
First Author: Chen AM
Year: 2000
Journal: Transplantation
Title: Porcine stem cell engraftment and seeding of murine thymus with class II+ cells in mice expressing porcine cytokines: toward tolerance induction across discordant xenogeneic barriers.
Volume: 69
Issue: 12
Pages: 2484-90
Publication
First Author: Yang YG
Year: 2000
Journal: Xenotransplantation
Title: Development and analysis of transgenic mice expressing porcine hematopoietic cytokines: a model for achieving durable porcine hematopoietic chimerism across an extensive xenogeneic barrier.
Volume: 7
Issue: 1
Pages: 58-64
Publication
First Author: Espuny-Camacho I
Year: 2017
Journal: Neuron
Title: Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.
Volume: 93
Issue: 5
Pages: 1066-1081.e8
Publication
First Author: Livák F
Year: 1999
Journal: J Immunol
Title: Characterization of TCR gene rearrangements during adult murine T cell development.
Volume: 162
Issue: 5
Pages: 2575-80
Publication
First Author: Serreze DV
Year: 2001
Journal: Diabetes
Title: Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.
Volume: 50
Issue: 9
Pages: 1992-2000
Publication
First Author: Stalder AK
Year: 1998
Journal: Am J Pathol
Title: Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor.
Volume: 153
Issue: 3
Pages: 767-83
Publication
First Author: Yang GX
Year: 2011
Journal: J Immunol
Title: CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease.
Volume: 186
Issue: 2
Pages: 1259-67
Publication
First Author: Qualls JE
Year: 2006
Journal: J Leukoc Biol
Title: Suppression of experimental colitis by intestinal mononuclear phagocytes.
Volume: 80
Issue: 4
Pages: 802-15
Publication
First Author: Pierce MA
Year: 2003
Journal: Diabetes
Title: Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice.
Volume: 52
Issue: 5
Pages: 1119-27
Publication
First Author: Zhang YW
Year: 2005
Journal: Oncogene
Title: Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor.
Volume: 24
Issue: 1
Pages: 101-6
Publication
First Author: Turley SJ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Endocrine self and gut non-self intersect in the pancreatic lymph nodes.
Volume: 102
Issue: 49
Pages: 17729-33
Publication
First Author: Takahama Y
Year: 1995
Journal: J Immunol
Title: Regulation of early T cell development by the engagement of TCR-beta complex expressed on fetal thymocytes from TCR-beta-transgenic scid mice.
Volume: 154
Issue: 11
Pages: 5862-9
Publication
First Author: Shores EW
Year: 1993
Journal: J Immunol
Title: Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR beta transgene.
Volume: 150
Issue: 4
Pages: 1263-75
Publication
First Author: Serreze DV
Year: 1995
Journal: Diabetes
Title: Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells.
Volume: 44
Issue: 12
Pages: 1392-8
Publication
First Author: Leeth CM
Year: 2016
Journal: Diabetes
Title: B-lymphocytes expressing an Ig specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice.
Volume: 65
Issue: 7
Pages: 1977-1987
Publication
First Author: Racine JJ
Year: 2020
Journal: J Immunol
Title: T Cells from NOD-PerIg Mice Target Both Pancreatic and Neuronal Tissue.
Volume: 205
Issue: 8
Pages: 2026-2038
Publication
First Author: Alba A
Year: 2004
Journal: J Immunol
Title: IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.
Volume: 173
Issue: 11
Pages: 6667-75
Publication
First Author: Jones RE
Year: 2019
Journal: Cell Rep
Title: Skeletal Stem Cell-Schwann Cell Circuitry in Mandibular Repair.
Volume: 28
Issue: 11
Pages: 2757-2766.e5
Publication
First Author: Waldner H
Year: 2006
Journal: J Immunol
Title: The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells.
Volume: 176
Issue: 9
Pages: 5455-62
Publication
First Author: Bosma GC
Year: 2002
Journal: J Exp Med
Title: DNA-dependent protein kinase activity is not required for immunoglobulin class switching.
Volume: 196
Issue: 11
Pages: 1483-95
Publication
First Author: Kiefer K
Year: 2008
Journal: J Immunol
Title: Antigen receptor editing in anti-DNA transitional B cells deficient for surface IgM.
Volume: 180
Issue: 9
Pages: 6094-106
Publication
First Author: Wei J
Year: 2008
Journal: Cancer Cell
Title: Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.
Volume: 13
Issue: 6
Pages: 483-95
Publication
First Author: Bridgett M
Year: 1998
Journal: Diabetes
Title: Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells.
Volume: 47
Issue: 12
Pages: 1848-56
Publication
First Author: Mähler M
Year: 1998
Journal: Am J Physiol
Title: Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis.
Volume: 274
Issue: 3 Pt 1
Pages: G544-51
Publication
First Author: Ambrosino E
Year: 2006
Journal: Cancer Res
Title: Immunosurveillance of Erbb2 carcinogenesis in transgenic mice is concealed by a dominant regulatory T-cell self-tolerance.
Volume: 66
Issue: 15
Pages: 7734-40
Publication
First Author: Hugues S
Year: 2002
Journal: Immunity
Title: Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells.
Volume: 16
Issue: 2
Pages: 169-81
Publication
First Author: Calderon B
Year: 2006
Journal: Am J Pathol
Title: In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model.
Volume: 169
Issue: 6
Pages: 2137-47
Publication
First Author: Phillips JM
Year: 2001
Journal: J Immunol
Title: Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes.
Volume: 167
Issue: 11
Pages: 6087-91
Publication
First Author: Luo X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells.
Volume: 104
Issue: 8
Pages: 2821-6
Publication
First Author: Mishra A
Year: 2017
Journal: Biol Open
Title: A novel immunodeficient NOD.SCID-rd1 mouse model of retinitis pigmentosa to investigate potential therapeutics and pathogenesis of retinal degeneration.
Volume: 6
Issue: 4
Pages: 449-462