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Search results 1 to 84 out of 84 for Prorp

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
9692 | PRORP
Type: gene
Organism: human
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Gene
100125795 | prorp
Type: gene
Organism: frog, western clawed
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Gene
299050 | Prorp
Type: gene
Organism: rat
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Gene
490650 | PRORP
Type: gene
Organism: dog, domestic
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Gene
452860 | PRORP
Type: gene
Organism: chimpanzee
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Gene
532995 | PRORP
Type: gene
Organism: cattle
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Gene
423325 | PRORP
Type: gene
Organism: chicken
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Gene
555630 | prorp
Type: gene
Organism: zebrafish
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Gene
694753 | PRORP
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1913382 | Prorp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0017758 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200030302 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195016880 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220025786 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180005989 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175016458 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1913382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215012708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005008773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210009506 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185000951 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205012266 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230014947 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000006635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190015834 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225040647 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010016151 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005003471 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029514 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010015839 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
28201688 | J:249591
First Author: Kuznetsova I
Year: 2017
Journal: Nucleic Acids Res
Title: Simultaneous processing and degradation of mitochondrial RNAs revealed by circularized RNA sequencing.
Volume: 45
Issue: 9
Pages: 5487-5500
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Publication
27498866 | J:238964
First Author: Rackham O
Year: 2016
Journal: Cell Rep
Title: Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly.
Volume: 16
Issue: 7
Pages: 1874-90
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Publication
24703694 | J:213151
First Author: Bogenhagen DF
Year: 2014
Journal: Cell Metab
Title: Initial steps in RNA processing and ribosome assembly occur at mitochondrial DNA nucleoids.
Volume: 19
Issue: 4
Pages: 618-29
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:384794
     
First Author: MGI and IMPC
Year: 2026
Journal: Database Release
Title: MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342609
       
First Author: UniProt
Year: 2021
Title: Electronic Gene Ontology annotations created by ARBA machine learning models
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:389486
     
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
34715011 | -
First Author: Hochberg I
Year: 2021
Journal: Am J Hum Genet
Title: Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations.
Volume: 108
Issue: 11
Pages: 2195-2204
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Publication
22549728 | -
First Author: Gutmann B
Year: 2012
Journal: Genes Dev
Title: PRORP proteins support RNase P activity in both organelles and the nucleus in Arabidopsis.
Volume: 26
Issue: 10
Pages: 1022-7
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DO Term
DOID:0070427 | combined oxidative phosphorylation deficiency 54
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Protein Domain
IPR031595 | PRORP-like_C
Type: Domain
Description: This entry represents a domain found in protein-only RNase P (PRORP), an enzyme that processes precursor tRNAs in human mitochondria and in all tRNA-using compartments of Arabidopsis thaliana. PRORP catalyses the maturation of the 5' ends of tRNA precursors [].This entry also includes Mitochondrial ribonuclease P catalytic subunit (MRPP3). MRPP3, also known as PRORP, is the catalytic ribonuclease component of mitochondrial ribonuclease P, a complex that also includes TRMT10C/MRPP1 and HSD17B10/MRPP2. This complex is responsible for cleaving tRNA molecules at their 5' ends [, , ]. The presence of TRMT10C/MRPP1 and HSD17B10/MRPP2 alongside MRPP3 is required for this 5' end cleavage activity to occur [].
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Protein
V9GWT5
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
V9GXF2
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
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Publication
22991464 | -
First Author: Howard MJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing.
Volume: 109
Issue: 40
Pages: 16149-54
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Publication
25953853 | -
First Author: Reinhard L
Year: 2015
Journal: Nucleic Acids Res
Title: Structure of the nuclease subunit of human mitochondrial RNase P.
Volume: 43
Issue: 11
Pages: 5664-72
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Protein Domain
IPR059192 | PIN_19
Type: Family
Description: This entry represents uncharacterised PIN domain-containing proteins in bacteria. PIN-like domains can be classified into distinct groups; this subgroup corresponds to PIN_19, they belong to the VapC-like nucleases [].The PIN domain-like superfamily comprises five major structural groups of nucleases that share a common Rossmann-like fold consisting of a central five-stranded parallel ��-sheet but differ significantly in their structural elaborations and functions. The FEN-like nucleases (Group 1) possess the most complex architecture with additional elements like a "helical arch"and "hydrophobic wedge,"utilising 6-7 acidic residues to coordinate two metal ions for structure-specific 5' nuclease activity in DNA replication and repair. VapC-like nucleases (Group 2) represent a stripped-down version with a minimal H2' helical insert and 3-5 active site residues, functioning primarily as endoribonucleases in prokaryotic toxin-antitoxin systems targeting specific RNA structures. NYN-like nucleases (Group 3) lack the helical insert after ��-strand 2, resulting in an exposed active site with four acidic residues predicted to coordinate one metal ion, though their catalytic mechanism remains experimentally uncharacterised. PRORP domains (Group 4) feature unique bent helices and an extended ��-sheet with 4-5 aspartates coordinating two metal ions, functioning as proteinaceous RNase P enzymes for 5' tRNA maturation in eukaryotic organelles. Mut7-C-like domains (Group 5) represent the most divergent group, lacking core elements ��-helix 3 and ��-strand 3, with reduced active site conservation and a C-terminal zinc ribbon insertion, showing variable nuclease activity that appears species-dependent [].
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Publication
18984158 | -
First Author: Holzmann J
Year: 2008
Journal: Cell
Title: RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme.
Volume: 135
Issue: 3
Pages: 462-74
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Protein
Q8JZY4
Organism: Mus musculus/domesticus
Length: 584  
Fragment?: false
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Protein
V9GXP4
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
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Publication
28575517 | -
First Author: Matelska D
Year: 2017
Journal: Nucleic Acids Res
Title: Comprehensive classification of the PIN domain-like superfamily.
Volume: 45
Issue: 12
Pages: 6995-7020
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