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Search results 1 to 100 out of 1086 for Ptf1a

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0.08s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Scattered
Stage: TS17
Assay Id: MGI:6695726
Age: embryonic day 10.5
Image: 5B Ptf1a
Note: Expression in pancreatic progenitor cells of dorsal pancreatic bud at E10.5 coinciding with Pdx1 and Ngn3 expression in scattered cells throughout pancreatic epithelium.
Specimen Label: 5B Ptf1a
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750320
Stage: TS20
Assay Id: MGI:6695726
Age: embryonic day 12.5
Image: S2B Ptf1a
Specimen Label: S2B Ptf1a
Detected: false
Specimen Num: 10
GXD Expression
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6695726
Age: embryonic day 9.5
Image: S4 Ptf1a
Note: Expression in foregut endoderm as early as E9.5.
Specimen Label: S4 Ptf1a
Detected: true
Specimen Num: 13
GXD Expression
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6695726
Age: embryonic day 12.5
Image: S2A Ptf1a
Note: Expression has begun to compartmentalize to distal tips of pancreatic epithelium.
Specimen Label: S2A Ptf1a
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6695726
Age: embryonic day 10.5
Image: S2C Ptf1a
Specimen Label: S2C Ptf1a
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3565123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6695726
Age: embryonic day 15.5
Image: S1 Ptf1a E15.5
Note: From E13.5 on, expression coincident with Ptf1a in all acinar cells.
Specimen Label: S1 Ptf1a E15.5
Detected: true
Specimen Num: 8
GXD Expression
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3565121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6695726
Age: embryonic day 13.5
Image: S1 Ptf1a E13.5
Note: From E13.5 on, expression coincident with Ptf1a in all acinar cells.
Specimen Label: S1 Ptf1a E13.5
Detected: true
Specimen Num: 7
Publication
First Author: Meredith DM
Year: 2009
Journal: J Neurosci
Title: Multiple transcriptional mechanisms control Ptf1a levels during neural development including autoregulation by the PTF1-J complex.
Volume: 29
Issue: 36
Pages: 11139-48
Publication
First Author: Fujiyama T
Year: 2018
Journal: Cell Rep
Title: Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain.
Volume: 24
Issue: 1
Pages: 79-94
Publication
First Author: Fukuda A
Year: 2008
Journal: Diabetes
Title: Reduction of Ptf1a gene dosage causes pancreatic hypoplasia and diabetes in mice.
Volume: 57
Issue: 9
Pages: 2421-31
Publication    
First Author: Krah NM
Year: 2015
Journal: Elife
Title: The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma.
Volume: 4
Publication
First Author: Burlison JS
Year: 2008
Journal: Dev Biol
Title: Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells.
Volume: 316
Issue: 1
Pages: 74-86
Publication
First Author: Fujitani Y
Year: 2006
Journal: Development
Title: Ptf1a determines horizontal and amacrine cell fates during mouse retinal development.
Volume: 133
Issue: 22
Pages: 4439-50
Publication
First Author: Kawaguchi Y
Year: 2002
Journal: Nat Genet
Title: The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors.
Volume: 32
Issue: 1
Pages: 128-34
GXD Expression  
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6695726
Age: embryonic day 11.5
Image: S1 Ptf1a E11.5
Specimen Label: S1 Ptf1a E11.5
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564520
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6695726
Age: embryonic day 12.5
Image: S1 Ptf1a E12.5
Note: Expression in multipotent progenitor cells (MPCs) residing in distal tipe of branching epithelium at periphery of pancreas.
Specimen Label: S1 Ptf1a E12.5
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1725615
Pattern: Widespread
Stage: TS15
Assay Id: MGI:6695726
Age: embryonic day 9.5
Image: S1 Ptf1a E9.5
Note: Expression throughout dorsal and ventral pancreatic buds.
Specimen Label: S1 Ptf1a E9.5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706715
Pattern: Widespread
Stage: TS15
Assay Id: MGI:6695726
Age: embryonic day 9.5
Image: S1 Ptf1a E9.5
Note: Expression throughout dorsal and ventral pancreatic buds.
Specimen Label: S1 Ptf1a E9.5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6695355
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6695726
Age: embryonic day 10.5
Image: S1 Ptf1a E10.5
Specimen Label: S1 Ptf1a E10.5
Detected: true
Specimen Num: 4
Publication
First Author: Russ JB
Year: 2015
Journal: J Neurosci
Title: Misexpression of ptf1a in cortical pyramidal cells in vivo promotes an inhibitory peptidergic identity.
Volume: 35
Issue: 15
Pages: 6028-37
Publication
First Author: Glasgow SM
Year: 2005
Journal: Development
Title: Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn.
Volume: 132
Issue: 24
Pages: 5461-9
Publication
First Author: Yamada M
Year: 2014
Journal: J Neurosci
Title: Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons.
Volume: 34
Issue: 14
Pages: 4786-800
Publication  
First Author: Jin K
Year: 2015
Journal: Mol Brain
Title: Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis.
Volume: 8
Pages: 28
Publication
First Author: Nishida K
Year: 2010
Journal: J Biol Chem
Title: Ptf1a directly controls expression of immunoglobulin superfamily molecules Nephrin and Neph3 in the developing central nervous system.
Volume: 285
Issue: 1
Pages: 373-80
Publication
First Author: Semba K
Year: 2013
Journal: PLoS Genet
Title: Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice.
Volume: 9
Issue: 2
Pages: e1003204
Publication
First Author: Fujiyama T
Year: 2009
Journal: Development
Title: Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1.
Volume: 136
Issue: 12
Pages: 2049-58
Publication
First Author: Nakhai H
Year: 2007
Journal: Development
Title: Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina.
Volume: 134
Issue: 6
Pages: 1151-60
Publication
First Author: Iskusnykh IY
Year: 2016
Journal: J Neurosci
Title: Loss of Ptf1a Leads to a Widespread Cell-Fate Misspecification in the Brainstem, Affecting the Development of Somatosensory and Viscerosensory Nuclei.
Volume: 36
Issue: 9
Pages: 2691-710
Publication
First Author: Pascual M
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression.
Volume: 104
Issue: 12
Pages: 5193-8
Publication
First Author: Millen KJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function.
Volume: 111
Issue: 17
Pages: E1777-86
Publication
First Author: Lugani F
Year: 2013
Journal: PLoS Genet
Title: A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.
Volume: 9
Issue: 2
Pages: e1003206
MGI Directed Relationship Property
Name: Non-mouse_Gene_Symbol
Value: Ptf1a
Publication
First Author: Henke RM
Year: 2009
Journal: Development
Title: Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cord.
Volume: 136
Issue: 17
Pages: 2945-54
Publication
First Author: Hoshino M
Year: 2005
Journal: Neuron
Title: Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum.
Volume: 47
Issue: 2
Pages: 201-13
Publication
First Author: Masui T
Year: 2007
Journal: Genes Dev
Title: Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex.
Volume: 21
Issue: 20
Pages: 2629-43
Publication
First Author: Hori K
Year: 2008
Journal: Genes Dev
Title: A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling.
Volume: 22
Issue: 2
Pages: 166-78
Publication
First Author: Krah NM
Year: 2019
Journal: Dev Cell
Title: Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism.
Volume: 50
Issue: 6
Pages: 744-754.e4
Publication
First Author: Hoang CQ
Year: 2016
Journal: Mol Cell Biol
Title: Transcriptional Maintenance of Pancreatic Acinar Identity, Differentiation, and Homeostasis by PTF1A.
Volume: 36
Issue: 24
Pages: 3033-3047
Publication
First Author: Chang JC
Year: 2013
Journal: Dev Cell
Title: Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits.
Volume: 25
Issue: 2
Pages: 182-95
Publication
First Author: Escalante A
Year: 2020
Journal: Cell Rep
Title: Spinal Inhibitory Ptf1a-Derived Neurons Prevent Self-Generated Itch.
Volume: 33
Issue: 8
Pages: 108422
Publication  
First Author: Zhang H
Year: 2022
Journal: Development
Title: Regulation of retinal amacrine cell generation by miR-216b and Foxn3.
Volume: 149
Issue: 2
Publication
First Author: Fukuda A
Year: 2006
Journal: J Clin Invest
Title: Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.
Volume: 116
Issue: 6
Pages: 1484-93
Publication
First Author: Yamamoto K
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Tissue-specific deletion of c-Jun in the pancreas has limited effects on pancreas formation.
Volume: 363
Issue: 4
Pages: 908-14
Publication
First Author: Ijichi H
Year: 2006
Journal: Genes Dev
Title: Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression.
Volume: 20
Issue: 22
Pages: 3147-60
Publication
First Author: Pan FC
Year: 2013
Journal: Development
Title: Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.
Volume: 140
Issue: 4
Pages: 751-64
Publication
First Author: Yamada M
Year: 2007
Journal: J Neurosci
Title: Origin of climbing fiber neurons and their developmental dependence on Ptf1a.
Volume: 27
Issue: 41
Pages: 10924-34
Publication  
First Author: Chen C
Year: 2019
Journal: Development
Title: Evidence of a developmental origin for β-cell heterogeneity using a dual lineage-tracing technology.
Volume: 146
Issue: 13
Publication
First Author: Borromeo MD
Year: 2014
Journal: Development
Title: A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord.
Volume: 141
Issue: 14
Pages: 2803-12
Publication
First Author: Johnson BL
Year: 2019
Journal: PLoS One
Title: Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice.
Volume: 14
Issue: 9
Pages: e0221810
Publication
First Author: Huang M
Year: 2008
Journal: Dev Biol
Title: Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons.
Volume: 322
Issue: 2
Pages: 394-405
Publication
First Author: Bröhl D
Year: 2008
Journal: Dev Biol
Title: A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord.
Volume: 322
Issue: 2
Pages: 381-93
Publication
First Author: Wu F
Year: 2013
Journal: J Neurosci
Title: Onecut1 is essential for horizontal cell genesis and retinal integrity.
Volume: 33
Issue: 32
Pages: 13053-65, 13065a
Publication
First Author: Hale MA
Year: 2014
Journal: Development
Title: The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.
Volume: 141
Issue: 16
Pages: 3123-33
Publication
First Author: Elhanani O
Year: 2020
Journal: Cell Rep
Title: REST Inhibits Direct Reprogramming of Pancreatic Exocrine to Endocrine Cells by Preventing PDX1-Mediated Activation of Endocrine Genes.
Volume: 31
Issue: 5
Pages: 107591
Publication    
First Author: Zhang Y
Year: 2017
Journal: Elife
Title: Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice.
Volume: 6
Publication
First Author: Miyazaki S
Year: 2016
Journal: PLoS One
Title: Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice.
Volume: 11
Issue: 8
Pages: e0161190
Publication
First Author: Ideno N
Year: 2019
Journal: Lab Invest
Title: A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination.
Volume: 99
Issue: 8
Pages: 1233-1244
Publication  
First Author: White JJ
Year: 2017
Journal: Nat Commun
Title: Genetic silencing of olivocerebellar synapses causes dystonia-like behaviour in mice.
Volume: 8
Pages: 14912
Publication
First Author: Krol A
Year: 2016
Journal: Development
Title: Fat3 and Ena/VASP proteins influence the emergence of asymmetric cell morphology in the developing retina.
Volume: 143
Issue: 12
Pages: 2172-82
Publication  
First Author: Hiraoka Y
Year: 2013
Journal: Mol Brain
Title: Delta-like 1 regulates Bergmann glial monolayer formation during cerebellar development.
Volume: 6
Pages: 25
Publication
First Author: Shibata W
Year: 2018
Journal: Sci Rep
Title: Overexpression of HER2 in the pancreas promotes development of intraductal papillary mucinous neoplasms in mice.
Volume: 8
Issue: 1
Pages: 6150
Publication
First Author: Algül H
Year: 2007
Journal: J Clin Invest
Title: Pancreas-specific RelA/p65 truncation increases susceptibility of acini to inflammation-associated cell death following cerulein pancreatitis.
Volume: 117
Issue: 6
Pages: 1490-501
Publication
First Author: Eser S
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging.
Volume: 108
Issue: 24
Pages: 9945-50
Publication
First Author: Veite-Schmahl MJ
Year: 2017
Journal: PLoS One
Title: The Mouse Model of Pancreatic Cancer Atlas (MMPCA) for classification of pancreatic cancer lesions: A large histological investigation of the Ptf1aCre/+;LSL-KrasG12D/+ transgenic mouse model of pancreatic cancer.
Volume: 12
Issue: 11
Pages: e0187552
Publication
First Author: Hidalgo-Sastre A
Year: 2020
Journal: Sci Rep
Title: Mir34a constrains pancreatic carcinogenesis.
Volume: 10
Issue: 1
Pages: 9654
Publication
First Author: Mohammed A
Year: 2012
Journal: Int J Cancer
Title: Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.
Volume: 131
Issue: 8
Pages: 1951-62
Publication
First Author: Ray KC
Year: 2014
Journal: Oncogene
Title: Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
Volume: 33
Issue: 7
Pages: 823-31
Publication
First Author: Tapfer A
Year: 2013
Journal: PLoS One
Title: X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.
Volume: 8
Issue: 3
Pages: e58439
Publication
First Author: Mukherjee P
Year: 2009
Journal: J Immunol
Title: Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition.
Volume: 182
Issue: 1
Pages: 216-24
Publication
First Author: Mello SS
Year: 2017
Journal: Genes Dev
Title: Neat1 is a p53-inducible lincRNA essential for transformation suppression.
Volume: 31
Issue: 11
Pages: 1095-1108
Publication
First Author: Tinder TL
Year: 2008
Journal: J Immunol
Title: MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma.
Volume: 181
Issue: 5
Pages: 3116-25
Publication
First Author: Hao F
Year: 2019
Journal: PLoS One
Title: Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice.
Volume: 14
Issue: 5
Pages: e0216603
Publication
First Author: Leal AS
Year: 2019
Journal: Sci Rep
Title: The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice.
Volume: 9
Issue: 1
Pages: 7072
Publication
First Author: Zhu L
Year: 2007
Journal: Am J Pathol
Title: Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia.
Volume: 171
Issue: 1
Pages: 263-73
Publication
First Author: Hingorani SR
Year: 2003
Journal: Cancer Cell
Title: Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
Volume: 4
Issue: 6
Pages: 437-50
Publication  
First Author: LaConti JJ
Year: 2015
Journal: BMC Genomics
Title: Distinct serum metabolomics profiles associated with malignant progression in the KrasG12D mouse model of pancreatic ductal adenocarcinoma.
Volume: 16 Suppl 1
Pages: S1
Publication
First Author: Mohammed A
Year: 2014
Journal: Cancer Prev Res (Phila)
Title: Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.
Volume: 7
Issue: 12
Pages: 1198-209
Publication
First Author: Schlesinger Y
Year: 2020
Journal: Nat Commun
Title: Single-cell transcriptomes of pancreatic preinvasive lesions and cancer reveal acinar metaplastic cells' heterogeneity.
Volume: 11
Issue: 1
Pages: 4516
Publication
First Author: Erener S
Year: 2021
Journal: Cell Rep Med
Title: Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
Volume: 2
Issue: 11
Pages: 100434
Publication
First Author: Liou GY
Year: 2015
Journal: Cancer Discov
Title: Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions.
Volume: 5
Issue: 1
Pages: 52-63
Publication
First Author: Veite-Schmahl MJ
Year: 2017
Journal: Br J Cancer
Title: HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.
Volume: 117
Issue: 5
Pages: 639-647
Publication
First Author: Sureban SM
Year: 2011
Journal: Cancer Res
Title: DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.
Volume: 71
Issue: 6
Pages: 2328-38
Publication
First Author: LaConti JJ
Year: 2011
Journal: PLoS One
Title: Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer.
Volume: 6
Issue: 6
Pages: e20687
Publication
First Author: Mohammed A
Year: 2012
Journal: Neoplasia
Title: Endogenous n-3 polyunsaturated fatty acids delay progression of pancreatic ductal adenocarcinoma in Fat-1-p48(Cre/+)-LSL-Kras(G12D/+) mice.
Volume: 14
Issue: 12
Pages: 1249-59
Publication
First Author: Mohammed A
Year: 2013
Journal: Transl Oncol
Title: Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling.
Volume: 6
Issue: 6
Pages: 649-59
Publication
First Author: Dong TS
Year: 2019
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Metformin alters the duodenal microbiome and decreases the incidence of pancreatic ductal adenocarcinoma promoted by diet-induced obesity.
Volume: 317
Issue: 6
Pages: G763-G772
Publication
First Author: Clark CE
Year: 2007
Journal: Cancer Res
Title: Dynamics of the immune reaction to pancreatic cancer from inception to invasion.
Volume: 67
Issue: 19
Pages: 9518-27
Publication
First Author: Mohammed A
Year: 2010
Journal: Cancer Prev Res (Phila)
Title: The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model.
Volume: 3
Issue: 11
Pages: 1417-26
Publication
First Author: Hocker JR
Year: 2013
Journal: Int J Cancer
Title: Mass profiling of serum to distinguish mice with pancreatic cancer induced by a transgenic Kras mutation.
Volume: 133
Issue: 11
Pages: 2662-71
Publication
First Author: Collins MA
Year: 2014
Journal: Gastroenterology
Title: MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice.
Volume: 146
Issue: 3
Pages: 822-834.e7
Publication  
First Author: Dréau D
Year: 2019
Journal: Front Oncol
Title: Combining the Specific Anti-MUC1 Antibody TAB004 and Lip-MSA-IL-2 Limits Pancreatic Cancer Progression in Immune Competent Murine Models of Pancreatic Ductal Adenocarcinoma.
Volume: 9
Pages: 330
Publication  
First Author: Chiblak S
Year: 2016
Journal: Sci Rep
Title: K-Ras and cyclooxygenase-2 coactivation augments intraductal papillary mucinous neoplasm and Notch1 mimicking human pancreas lesions.
Volume: 6
Pages: 29455
Publication
First Author: Handler J
Year: 2018
Journal: Oncogene
Title: Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure.
Volume: 37
Issue: 31
Pages: 4334-4342
Publication
First Author: Janakiram NB
Year: 2017
Journal: Immunology
Title: Loss of natural killer T cells promotes pancreatic cancer in LSL-KrasG12D/+ mice.
Volume: 152
Issue: 1
Pages: 36-51
Publication
First Author: Aichler M
Year: 2012
Journal: J Pathol
Title: Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.
Volume: 226
Issue: 5
Pages: 723-34
Publication
First Author: Schmahl MJ
Year: 2018
Journal: PLoS One
Title: NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.
Volume: 13
Issue: 7
Pages: e0200658