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Search results 1 to 100 out of 169 for Rad17

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
5884 | RAD17
Type: gene
Organism: human
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Gene
100379791 | rad17
Type: gene
Organism: frog, western clawed
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Gene
513600 | RAD17
Type: gene
Organism: cattle
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Gene
700116 | RAD17
Type: gene
Organism: macaque, rhesus
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Gene
310034 | Rad17
Type: gene
Organism: rat
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Gene
478088 | RAD17
Type: gene
Organism: dog, domestic
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Gene
461832 | RAD17
Type: gene
Organism: chimpanzee
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Gene
404778 | RAD17
Type: gene
Organism: chicken
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Gene
436934 | rad17
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:1333807 | Rad17
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR016587 | Rad17
Type: Family
Description: This entry represents Rad17 from budding yeast (the homologue of human and S. pombe Rad1). Rad17 is a component of the checkpoint clamp complex (Ddc1/Mec3/Rad17) involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes [, , ]. In S. cerevisiae, the Ddc1-Mec3-Rad17 complex associates with sites of DNA damage and modulates the Mec1 signaling pathway and the activation of Rad53 in response to DNA damage at phase G1 []. The complex also physically regulates DNA polymerase zeta-dependent mutagenesis by controlling the access of polymerase zeta to damaged DNA []. Contrary to its human counterpart, the 9-1-1 complex, the checkpoint clamp complex shows no detectable exonuclease activity []. It's worth noting that the name, Rad17, has been used for a different protein in human and S. pombe. The homologue of the human and S. pombe Rad17 in budding yeast is Rad24.
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Publication
15297881 | J:93156
First Author: Budzowska M
Year: 2004
Journal: EMBO J
Title: Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.
Volume: 23
Issue: 17
Pages: 3548-58
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Publication
10480350 | J:57491
First Author: von Deimling F
Year: 1999
Journal: Hum Genet
Title: Human and mouse RAD17 genes: identification, localization, genomic structure and histological expression pattern in normal testis and seminoma.
Volume: 105
Issue: 1-2
Pages: 17-27
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Publication
9933569 | J:52874
First Author: Bluyssen HA
Year: 1999
Journal: Genomics
Title: Human and mouse homologs of the Schizosaccharomyces pombe rad17+ cell cycle checkpoint control gene.
Volume: 55
Issue: 2
Pages: 219-28
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Publication
9869296 | J:52150
First Author: Bao S
Year: 1998
Journal: Cell Growth Differ
Title: The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint.
Volume: 9
Issue: 12
Pages: 961-7
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Gene
9206 | RAD17P2
Type: gene
Organism: human
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Gene
9207 | RAD17P1
Type: gene
Organism: human
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Publication
9670034 | -
First Author: Paciotti V
Year: 1998
Journal: EMBO J
Title: Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.
Volume: 17
Issue: 14
Pages: 4199-209
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Publication
16169844 | -
First Author: Sabbioneda S
Year: 2005
Journal: J Biol Chem
Title: The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae.
Volume: 280
Issue: 46
Pages: 38657-65
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Publication
7491494 | -
First Author: Lydall D
Year: 1995
Journal: Science
Title: Yeast checkpoint genes in DNA damage processing: implications for repair and arrest.
Volume: 270
Issue: 5241
Pages: 1488-91
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Publication
8649984 | -
First Author: Siede W
Year: 1996
Journal: Nucleic Acids Res
Title: Cloning and characterization of RAD17, a gene controlling cell cycle responses to DNA damage in Saccharomyces cerevisiae.
Volume: 24
Issue: 9
Pages: 1669-75
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Publication
9891048 | -
First Author: Kondo T
Year: 1999
Journal: Mol Cell Biol
Title: Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway.
Volume: 19
Issue: 2
Pages: 1136-43
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Publication
12604797 | -
First Author: Majka J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint.
Volume: 100
Issue: 5
Pages: 2249-54
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Protein Coding Gene
MGP_CAROLIEiJ_G0018844 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020888 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020839 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020629 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1333807 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021273 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020148 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020696 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020205 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015916 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019723 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3487163
Assay Type: RT-PCR
Annotation Date: 2004-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3487255
Age: embryonic day 8.5
Specimen Label: +/5'delta
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3487163
Assay Type: RT-PCR
Annotation Date: 2004-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3487255
Age: embryonic day 8.5
Specimen Label: 5' delta/5' delta
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3487163
Assay Type: RT-PCR
Annotation Date: 2004-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3487255
Age: embryonic day 8.5
Specimen Label: +/+
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3487257
Assay Type: Western blot
Annotation Date: 2004-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3487258
Age: embryonic day 8.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3487257
Assay Type: Western blot
Annotation Date: 2004-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3487258
Age: embryonic day 8.5
Specimen Label: +/5' delta
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3487257
Assay Type: Western blot
Annotation Date: 2004-11-22
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:3487258
Age: embryonic day 8.5
Specimen Label: 5' delta/5' delta
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7412812
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691016
Stage: TS16
Assay Id: MGI:7412903
Age: embryonic day 10.0
Image: 2
Specimen Label: E10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7412812
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7412903
Age: embryonic day 18.0
Image: 2
Specimen Label: E18
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7412812
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7412903
Age: postnatal month 2
Image: 2
Specimen Label: 2 months
Detected: true
Specimen Num: 3
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Publication
9705507 | J:49975
First Author: Udell CM
Year: 1998
Journal: Nucleic Acids Res
Title: HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control gene.
Volume: 26
Issue: 17
Pages: 3971-6
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Publication
20368419 | J:159288
First Author: Kumar A
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.
Volume: 107
Issue: 16
Pages: 7491-6
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Publication
19213844 | J:158060
First Author: Chesnokova V
Year: 2009
Journal: Endocrinology
Title: Diminished pancreatic beta-cell mass in securin-null mice is caused by beta-cell apoptosis and senescence.
Volume: 150
Issue: 6
Pages: 2603-10
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Publication
18722365 | J:141953
First Author: Derradji H
Year: 2008
Journal: Dev Biol
Title: Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects.
Volume: 322
Issue: 2
Pages: 302-13
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Publication
34746147 | J:314268
 
First Author: Akagawa R
Year: 2021
Journal: Front Cell Dev Biol
Title: Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.
Volume: 9
Pages: 753175
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Publication
22560297 | J:184521
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
11687627 | -
First Author: Post S
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage.
Volume: 98
Issue: 23
Pages: 13102-7
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Publication
14500819 | -
First Author: Post SM
Year: 2003
Journal: Nucleic Acids Res
Title: The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon.
Volume: 31
Issue: 19
Pages: 5568-75
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GO Term
GO:0031389 | Rad17 RFC-like complex
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Publication
10232579 | -
First Author: Bao S
Year: 1999
Journal: Cancer Res
Title: HRad17, a human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, is overexpressed in colon carcinoma.
Volume: 59
Issue: 9
Pages: 2023-8
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Protein
A0A286YCW1
Organism: Mus musculus/domesticus
Length: 229  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 1
Description: Cell cycle checkpoint protein RAD17
Type: chain
End: 688
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Publication
10871397 | J:63287
First Author: Venclovas C
Year: 2000
Journal: Nucleic Acids Res
Title: Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes.
Volume: 28
Issue: 13
Pages: 2481-93
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Protein
Q6NXW6
Organism: Mus musculus/domesticus
Length: 688  
Fragment?: false
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Gene
106997512 | LOC106997512
Type: gene
Organism: macaque, rhesus
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Gene
108705312 | rad17.S
Type: gene
Organism: frog, African clawed
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Gene
398572 | rad17.L
Type: gene
Organism: frog, African clawed
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