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Search results 1 to 100 out of 167 for Rasgrp1

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0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Sharma A
Year: 2014
Journal: Carcinogenesis
Title: Targeted deletion of RasGRP1 impairs skin tumorigenesis.
Volume: 35
Issue: 5
Pages: 1084-91
Publication
First Author: Shen S
Year: 2011
Journal: J Immunol
Title: Critical roles of RasGRP1 for invariant NKT cell development.
Volume: 187
Issue: 9
Pages: 4467-73
Publication      
First Author: Baars MJD
Year: 2020
Journal: Eur J Immunol
Title: Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity.
Publication
First Author: Priatel JJ
Year: 2010
Journal: J Immunol
Title: RasGRP1 regulates antigen-induced developmental programming by naive CD8 T cells.
Volume: 184
Issue: 2
Pages: 666-76
Publication
First Author: Chen Y
Year: 2012
Journal: J Immunol
Title: Differential requirement of RasGRP1 for γδ T cell development and activation.
Volume: 189
Issue: 1
Pages: 61-71
Publication
First Author: Karra L
Year: 2020
Journal: Oncogene
Title: Increased baseline RASGRP1 signals enhance stem cell fitness during native hematopoiesis.
Volume: 39
Issue: 45
Pages: 6920-6934
Publication
First Author: Golec DP
Year: 2016
Journal: J Immunol
Title: RasGRP1 and RasGRP3 Are Required for Efficient Generation of Early Thymic Progenitors.
Volume: 197
Issue: 5
Pages: 1743-53
Publication
First Author: Priatel JJ
Year: 2002
Journal: Immunity
Title: RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.
Volume: 17
Issue: 5
Pages: 617-27
Publication
First Author: Liu Y
Year: 2007
Journal: J Exp Med
Title: An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response.
Volume: 204
Issue: 1
Pages: 93-103
Publication
First Author: Eshraghi M
Year: 2020
Journal: Sci Adv
Title: RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease.
Volume: 6
Issue: 18
Pages: eaaz7001
Publication
First Author: Depeille P
Year: 2015
Journal: Nat Cell Biol
Title: RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.
Volume: 17
Issue: 6
Pages: 804-15
Publication
First Author: Sharma A
Year: 2010
Journal: J Biol Chem
Title: RasGRP1 is essential for ras activation by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate in epidermal keratinocytes.
Volume: 285
Issue: 21
Pages: 15724-30
Publication
First Author: Luke CT
Year: 2007
Journal: Cancer Res
Title: RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis.
Volume: 67
Issue: 21
Pages: 10190-7
Publication
First Author: Priatel JJ
Year: 2006
Journal: J Immunol
Title: RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development.
Volume: 177
Issue: 3
Pages: 1470-80
Publication
First Author: Tazmini G
Year: 2009
Journal: Biochim Biophys Acta
Title: Membrane localization of RasGRP1 is controlled by an EF-hand, and by the GEF domain.
Volume: 1793
Issue: 3
Pages: 447-61
Publication
First Author: Guo B
Year: 2016
Journal: J Immunol
Title: RasGRP1 Is an Essential Signaling Molecule for Development of B1a Cells with Autoantigen Receptors.
Volume: 196
Issue: 6
Pages: 2583-90
Publication
First Author: Coughlin JJ
Year: 2005
Journal: J Immunol
Title: RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling.
Volume: 175
Issue: 11
Pages: 7179-84
Publication
First Author: Shahani N
Year: 2016
Journal: Sci Signal
Title: RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.
Volume: 9
Issue: 454
Pages: ra111
Publication
First Author: Priatel JJ
Year: 2007
Journal: J Immunol
Title: Chronic immunodeficiency in mice lacking RasGRP1 results in CD4 T cell immune activation and exhaustion.
Volume: 179
Issue: 4
Pages: 2143-52
Publication
First Author: Ko B
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Phorbol ester stimulation of RasGRP1 regulates the sodium-chloride cotransporter by a PKC-independent pathway.
Volume: 104
Issue: 50
Pages: 20120-5
Publication
First Author: Fuller DM
Year: 2012
Journal: PLoS One
Title: Regulation of RasGRP1 function in T cell development and activation by its unique tail domain.
Volume: 7
Issue: 6
Pages: e38796
Publication
First Author: Golec DP
Year: 2017
Journal: J Exp Med
Title: Thymic progenitors of TCRαβ+ CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development.
Volume: 214
Issue: 8
Pages: 2421-2435
Publication
First Author: Takami M
Year: 2018
Journal: Eur J Immunol
Title: TGF-β suppresses RasGRP1 expression and supports regulatory T cell resistance against p53-induced CD28-dependent T-cell apoptosis.
Volume: 48
Issue: 12
Pages: 1938-1943
Publication    
First Author: Gbenedio OM
Year: 2019
Journal: JCI Insight
Title: RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer.
Volume: 5
Allele
Name: transgene insertion PO14, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion PO1, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
Publication
First Author: Beaulieu N
Year: 2007
Journal: Mol Biol Cell
Title: Regulation of RasGRP1 by B cell antigen receptor requires cooperativity between three domains controlling translocation to the plasma membrane.
Volume: 18
Issue: 8
Pages: 3156-68
Publication
First Author: Diez FR
Year: 2009
Journal: Am J Pathol
Title: RasGRP1 transgenic mice develop cutaneous squamous cell carcinomas in response to skin wounding: potential role of granulocyte colony-stimulating factor.
Volume: 175
Issue: 1
Pages: 392-9
Publication
First Author: Wen Z
Year: 2021
Journal: Blood
Title: Nras Q61R/+ and Kras-/- cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors.
Volume: 137
Issue: 23
Pages: 3259-3271
Publication
First Author: Norment AM
Year: 2003
Journal: J Immunol
Title: Transgenic expression of RasGRP1 induces the maturation of double-negative thymocytes and enhances the production of CD8 single-positive thymocytes.
Volume: 170
Issue: 3
Pages: 1141-9
Publication  
First Author: Daley SR
Year: 2013
Journal: Elife
Title: Rasgrp1 mutation increases naive T-cell CD44 expression and drives mTOR-dependent accumulation of Helios⁺ T cells and autoantibodies.
Volume: 2
Pages: e01020
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: transgenic, mutant stock
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Rasgrp1-cre)PO14Gsat/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Rasgrp1-cre)PO1Gsat/?
Background: involves: 129S4/SvJaeSor * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Gerfen CR
Year: 2013
Journal: Neuron
Title: GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits.
Volume: 80
Issue: 6
Pages: 1368-83
Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
Allele
Name: RAS guanyl releasing protein 1; targeted mutation 2, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Inducible, Recombinase, Reporter
Publication      
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Haddock.
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for sea_bass.
Publication
First Author: Layer K
Year: 2003
Journal: Immunity
Title: Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1.
Volume: 19
Issue: 2
Pages: 243-55
Publication
First Author: Myers DR
Year: 2019
Journal: Cell Rep
Title: Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells.
Volume: 27
Issue: 6
Pages: 1858-1874.e6
Publication  
First Author: Berg DJ
Year: 2019
Journal: eNeuro
Title: Transcriptomic Signatures of Postnatal and Adult Intrinsically Photosensitive Ganglion Cells.
Volume: 6
Issue: 4
Publication
First Author: Bartlett A
Year: 2013
Journal: J Immunol
Title: Multiple checkpoint breach of B cell tolerance in Rasgrp1-deficient mice.
Volume: 191
Issue: 7
Pages: 3605-13
Publication
First Author: Song X
Year: 2013
Journal: PLoS One
Title: RasGRPs are targets of the anti-cancer agent ingenol-3-angelate.
Volume: 8
Issue: 8
Pages: e72331
Publication
First Author: Chen X
Year: 2008
Journal: J Immunol
Title: Preferential development of CD4 and CD8 T regulatory cells in RasGRP1-deficient mice.
Volume: 180
Issue: 9
Pages: 5973-82
Publication
First Author: Zhu M
Year: 2012
Journal: J Biol Chem
Title: The role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development.
Volume: 287
Issue: 11
Pages: 8135-43
Publication  
First Author: Guo B
Year: 2019
Journal: Cell Immunol
Title: Impairment of PD-L2 positive B1a cells enhances susceptibility to sepsis in RasGRP1-deficient mice.
Volume: 346
Pages: 103993
Publication
First Author: Kortum RL
Year: 2012
Journal: Mol Cell Biol
Title: Deconstructing Ras signaling in the thymus.
Volume: 32
Issue: 14
Pages: 2748-59
Publication
First Author: Fuller DM
Year: 2012
Journal: J Immunol
Title: The importance of the Erk pathway in the development of linker for activation of T cells-mediated autoimmunity.
Volume: 189
Issue: 8
Pages: 4005-13
Publication
First Author: Coughlin JJ
Year: 2006
Journal: Immunol Lett
Title: The role of RasGRPs in regulation of lymphocyte proliferation.
Volume: 105
Issue: 1
Pages: 77-82
Publication
First Author: Smith C
Year: 2016
Journal: J Immunol
Title: CD275-Independent IL-17-Producing T Follicular Helper-like Cells in Lymphopenic Autoimmune-Prone Mice.
Volume: 196
Issue: 12
Pages: 4935-46
Publication
First Author: Golec DP
Year: 2013
Journal: PLoS One
Title: RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.
Volume: 8
Issue: 1
Pages: e53300
Publication
First Author: Gorentla BK
Year: 2011
Journal: Blood
Title: Negative regulation of mTOR activation by diacylglycerol kinases.
Volume: 117
Issue: 15
Pages: 4022-31
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Dower NA
Year: 2000
Journal: Nat Immunol
Title: RasGRP is essential for mouse thymocyte differentiation and TCR signaling.
Volume: 1
Issue: 4
Pages: 317-21
Publication      
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for grouper.
Publication      
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for naejangsan.
Publication
First Author: Charpentier JC
Year: 2020
Journal: Nat Commun
Title: Macropinocytosis drives T cell growth by sustaining the activation of mTORC1.
Volume: 11
Issue: 1
Pages: 180
Publication
First Author: Ferretti A
Year: 2016
Journal: J Immunol
Title: Autoantibody-Mediated Pulmonary Alveolar Proteinosis in Rasgrp1-Deficient Mice.
Volume: 197
Issue: 2
Pages: 470-9
GXD Expression        
Probe: MGI:3776268
Assay Type: RT-PCR
Annotation Date: 2008-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:3776281
Age: embryonic day 13.0
Specimen Label: E13
Specimen Num: 3
GXD Expression        
Probe: MGI:3776268
Assay Type: RT-PCR
Annotation Date: 2008-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3776281
Age: embryonic day 17.0
Specimen Label: E17
Specimen Num: 4
GXD Expression      
Probe: MGI:3776268
Assay Type: RT-PCR
Annotation Date: 2018-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6111381
Age: postnatal
Specimen Label: Balb/c Mouse
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6842419
Assay Type: RT-PCR
Annotation Date: 2021-12-31
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6842481
Age: embryonic day 13.5
Image: 7
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6842419
Assay Type: RT-PCR
Annotation Date: 2021-12-31
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6842481
Age: embryonic day 13.5
Image: 7
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_11
Specimen Label: euxassay_005719_11
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_12
Specimen Label: euxassay_005719_12
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_13
Specimen Label: euxassay_005719_13
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_14
Specimen Label: euxassay_005719_14
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1777823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_08
Specimen Label: euxassay_005719_08
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1777823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_09
Specimen Label: euxassay_005719_09
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1777823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_10
Specimen Label: euxassay_005719_10
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1777823
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_14
Specimen Label: euxassay_005719_14
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1777823
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_15
Specimen Label: euxassay_005719_15
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1777823
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_16
Specimen Label: euxassay_005719_16
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_10
Specimen Label: euxassay_005719_10
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_11
Specimen Label: euxassay_005719_11
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:2361541
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827629
Age: embryonic day 14.5
Image: euxassay_005719_12
Specimen Label: euxassay_005719_12
Detected: true
Specimen Num: 5