| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
893
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Smith SB |
| Year: |
2010 |
| Journal: |
Nature |
| Title: |
Rfx6 directs islet formation and insulin production in mice and humans. |
| Volume: |
463 |
| Issue: |
7282 |
| Pages: |
775-80 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Soyer J |
| Year: |
2010 |
| Journal: |
Development |
| Title: |
Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. |
| Volume: |
137 |
| Issue: |
2 |
| Pages: |
203-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Piccand J |
| Year: |
2014 |
| Journal: |
Cell Rep |
| Title: |
Rfx6 maintains the functional identity of adult pancreatic β cells. |
| Volume: |
9 |
| Issue: |
6 |
| Pages: |
2219-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Piccand J |
| Year: |
2019 |
| Journal: |
Mol Metab |
| Title: |
Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production. |
| Volume: |
29 |
|
| Pages: |
24-39 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki K |
| Year: |
2013 |
| Journal: |
J Biol Chem |
| Title: |
Transcriptional regulatory factor X6 (Rfx6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine K-cells and is involved in GIP hypersecretion in high fat diet-induced obesity. |
| Volume: |
288 |
| Issue: |
3 |
| Pages: |
1929-38 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Puri S |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice. |
| Volume: |
8 |
| Issue: |
8 |
| Pages: |
e72213 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muñoz-Bravo JL |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. |
| Volume: |
11 |
| Issue: |
10 |
| Pages: |
e0164714 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Flanagan SE |
| Year: |
2014 |
| Journal: |
Cell Metab |
| Title: |
Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man. |
| Volume: |
19 |
| Issue: |
1 |
| Pages: |
146-54 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418354 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2010-01-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750321 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:4418355 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
E13.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418354 |
| Assay Type: |
Northern blot |
| Annotation Date: |
2010-01-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:4418355 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418356 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2010-01-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750321 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:4418357 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
E13.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418356 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2010-01-21 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:4418357 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1636317 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 10.5 |
| Image: |
5A |
| Note: |
Expression is present in the developing alpha cells of the pancreas. |
| Specimen Label: |
5A |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1636317 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Expression is almost completely ablated in the mutant. |
| Specimen Label: |
Not shown |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1737328 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692719 |
| Age: |
postnatal adult |
| Image: |
TCP_2460298 |
| Note: |
kidney |
| Specimen Label: |
TCP_2460298 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619815 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 9.5 |
|
|
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619819 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1640519 |
| Pattern: |
Non-Uniform |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is strong in the interdigital region and moderate in the antero-distal, antero-proximal, posterior-distal and posterior-proximal regions of the limb. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1680017 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Staining is present in the olfactory placode. |
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1680019 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is present in the olfactory placode. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1619419 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is present in the otic pit. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270515 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 9.5 |
|
| Note: |
Staining is present in the proximal limb. |
| Specimen Label: |
Table S4 - E9.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270517 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Staining is present in the middle limb. |
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270519 |
| Pattern: |
Non-Uniform |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 11.5 |
|
| Note: |
Staining is strong in the middle limb and moderate in the progress zone. |
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1610517 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 10.5 |
|
|
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1684619 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750320 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 12.5 |
| Image: |
S2 A |
| Note: |
Expression is primarily present in non-dividing cells; only rarely is it present in dividing cells. |
| Specimen Label: |
S2 A |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 13.5 |
| Image: |
S2 B |
| Note: |
Expression is primarily present in non-dividing cells; only rarely is it present in dividing cells. |
| Specimen Label: |
S2 B |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 15.5 |
| Image: |
S2 C |
| Note: |
Expression is primarily present in non-dividing cells; only rarely is it present in dividing cells. |
| Specimen Label: |
S2 C |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750326 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 18.5 |
| Image: |
S2 D |
| Note: |
Expression is primarily present in non-dividing cells; only rarely is it present in dividing cells. |
| Specimen Label: |
S2 D |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 15.5 |
| Image: |
5B |
| Note: |
Expression is present in the developing alpha cells of the pancreas. |
| Specimen Label: |
5B |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 15.5 |
| Image: |
5C |
| Note: |
Expression is present in the developing beta cells of the pancreas. |
| Specimen Label: |
5C |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 14.5 |
| Image: |
4B |
|
| Specimen Label: |
4B |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 14.5 |
| Image: |
4D |
| Note: |
Expression in the mutant is the same as in wild type. |
| Specimen Label: |
4D |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 14.5 |
| Image: |
4F |
| Note: |
Expression in the mutant is the same as in wild type. |
| Specimen Label: |
4F |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 14.5 |
| Image: |
4H |
| Note: |
Expression in the mutant is the same as in wild type. |
| Specimen Label: |
4H |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 15.5 |
| Image: |
3A |
|
| Specimen Label: |
3A |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 15.5 |
| Image: |
3C |
|
| Specimen Label: |
3C |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 15.5 |
| Image: |
3E |
|
| Specimen Label: |
3E |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 15.5 |
| Image: |
2E/F |
| Note: |
Expression appears to be present in the developing islet cells of the pancreas. |
| Specimen Label: |
2E/F |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 15.5 |
| Image: |
2G |
| Note: |
Expression appears to be present in the developing islet cells of the pancreas. |
| Specimen Label: |
2G |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1750323 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 15.5 |
| Image: |
2H |
|
| Specimen Label: |
2H |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1928728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692719 |
| Age: |
postnatal adult |
| Image: |
TCP_2460297 |
|
| Specimen Label: |
TCP_2460297 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1666917 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 10.5 |
|
| Note: |
Staining is present in the otic pit. |
| Specimen Label: |
Table S4 - E10.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3292814 |
| Pattern: |
Not Specified |
| Stage: |
TS14 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 9.0 |
| Image: |
1B |
| Note: |
There is broad expression in the gut endoderm. |
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3292817 |
| Pattern: |
Not Specified |
| Stage: |
TS17 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 10.5 |
| Image: |
1F |
|
| Specimen Label: |
1F |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3292728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:4418318 |
| Age: |
postnatal adult |
| Image: |
5E |
| Note: |
There was expression present in the beta cells. |
| Specimen Label: |
5E |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3292728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:4418318 |
| Age: |
postnatal adult |
| Image: |
5D |
| Note: |
There was expression present in the alpha cells. |
| Specimen Label: |
5D |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3292728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:4418318 |
| Age: |
postnatal adult |
| Image: |
5F |
| Note: |
Expression is present in delta cells. |
| Specimen Label: |
5F |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3292728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:4418318 |
| Age: |
postnatal adult |
| Image: |
5G |
| Note: |
Expression is present in gamma cells. |
| Specimen Label: |
5G |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1706615 |
| Pattern: |
Not Specified |
| Stage: |
TS15 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 9.5 |
| Image: |
1D/E |
| Note: |
Expression is present in the nascent pancreatic buds. |
| Specimen Label: |
1D/E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1706617 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 10.5 |
| Image: |
1G |
| Note: |
Expression appears to be present in the differentiating endocrine (islet) cells of the pancreas. |
| Specimen Label: |
1G |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1706617 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 10.5 |
| Image: |
1H |
| Note: |
Expression appears to be present in the differentiating endocrine (islet) cells of the pancreas. |
| Specimen Label: |
1H |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418273 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1706617 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:4418318 |
| Age: |
embryonic day 10.5 |
| Image: |
2B/C |
| Note: |
Expression appears to be present in the developing islet cells of the pancreas. |
| Specimen Label: |
2B/C |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692719 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1872018 |
|
| Specimen Label: |
UC Davis_1872018 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4418282 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-01-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1606214 |
| Pattern: |
Not Specified |
| Stage: |
TS14 |
| Assay Id: |
MGI:4418300 |
| Age: |
embryonic day 9.0 |
| Image: |
1A |
| Note: |
There is broad expression in the gut endoderm. |
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1929028 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692719 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1872022 |
|
| Specimen Label: |
UC Davis_1872022 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692719 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1872020 |
|
| Specimen Label: |
UC Davis_1872020 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3276428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6692719 |
| Age: |
postnatal adult |
| Image: |
UC Davis_1872021 |
|
| Specimen Label: |
UC Davis_1872021 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4845473 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-12-22 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1618419 |
| Pattern: |
Not Specified |
| Stage: |
TS19 |
| Assay Id: |
MGI:4848998 |
| Age: |
embryonic day 11.5 |
|
|
| Specimen Label: |
Table S4 - E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magnuson MA |
| Year: |
2013 |
| Journal: |
Cell Metab |
| Title: |
Pancreas-specific Cre driver lines and considerations for their prudent use. |
| Volume: |
18 |
| Issue: |
1 |
| Pages: |
9-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Serafimidis I |
| Year: |
2011 |
| Journal: |
Mol Cell Biol |
| Title: |
G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesis. |
| Volume: |
31 |
| Issue: |
22 |
| Pages: |
4442-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zinina VV |
| Year: |
2023 |
| Journal: |
Cells |
| Title: |
TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine. |
| Volume: |
12 |
| Issue: |
11 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Churchill AJ |
| Year: |
2017 |
| Journal: |
Elife |
| Title: |
Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development. |
| Volume: |
6 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ohta Y |
| Year: |
2011 |
| Journal: |
Diabetes |
| Title: |
Convergence of the insulin and serotonin programs in the pancreatic β-cell. |
| Volume: |
60 |
| Issue: |
12 |
| Pages: |
3208-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abdellatif AM |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development. |
| Volume: |
11 |
| Issue: |
2 |
| Pages: |
e0150010 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ansarullah |
| Year: |
2021 |
| Journal: |
Nature |
| Title: |
Inceptor counteracts insulin signalling in β-cells to control glycaemia. |
| Volume: |
590 |
| Issue: |
7845 |
| Pages: |
326-331 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yokoyama S |
| Year: |
2009 |
| Journal: |
Dev Cell |
| Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
| Volume: |
17 |
| Issue: |
6 |
| Pages: |
836-48 |
|
•
•
•
•
•
|