| Type | Details | Score | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | human |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | frog, western clawed |  | • • • • • | 
          
              | Gene |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | dog, domestic |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | chimpanzee |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | cattle |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | chicken |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | zebrafish |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | macaque, rhesus |  | • • • • • | 
          
              | Protein | 
              
                | Organism: | Mus musculus/domesticus |  
                | Length: | 893  |  
                | Fragment?: | false |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Smith SB |  
                | Year: | 2010 |  
                | Journal: | Nature |  
                | Title: | Rfx6 directs islet formation and insulin production in mice and humans. |  
                | Volume: | 463 |  
                | Issue: | 7282 |  
                | Pages: | 775-80 |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | human |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Soyer J |  
                | Year: | 2010 |  
                | Journal: | Development |  
                | Title: | Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. |  
                | Volume: | 137 |  
                | Issue: | 2 |  
                | Pages: | 203-12 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Piccand J |  
                | Year: | 2014 |  
                | Journal: | Cell Rep |  
                | Title: | Rfx6 maintains the functional identity of adult pancreatic β cells. |  
                | Volume: | 9 |  
                | Issue: | 6 |  
                | Pages: | 2219-32 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Piccand J |  
                | Year: | 2019 |  
                | Journal: | Mol Metab |  
                | Title: | Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production. |  
                | Volume: | 29 |  
                |  |  
                | Pages: | 24-39 |  | • • • • • | 
          
              | Gene | 
              
                | Type: | gene |  
                | Organism: | human |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Suzuki K |  
                | Year: | 2013 |  
                | Journal: | J Biol Chem |  
                | Title: | Transcriptional regulatory factor X6 (Rfx6) increases gastric inhibitory polypeptide (GIP) expression in enteroendocrine K-cells and is involved in GIP hypersecretion in high fat diet-induced obesity. |  
                | Volume: | 288 |  
                | Issue: | 3 |  
                | Pages: | 1929-38 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Puri S |  
                | Year: | 2013 |  
                | Journal: | PLoS One |  
                | Title: | Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice. |  
                | Volume: | 8 |  
                | Issue: | 8 |  
                | Pages: | e72213 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Muñoz-Bravo JL |  
                | Year: | 2016 |  
                | Journal: | PLoS One |  
                | Title: | Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. |  
                | Volume: | 11 |  
                | Issue: | 10 |  
                | Pages: | e0164714 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Flanagan SE |  
                | Year: | 2014 |  
                | Journal: | Cell Metab |  
                | Title: | Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man. |  
                | Volume: | 19 |  
                | Issue: | 1 |  
                | Pages: | 146-54 |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | Mus caroli |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | mouse, laboratory |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | Mus pahari |  | • • • • • | 
          
              | Protein Coding Gene | 
              
                | Type: | protein_coding_gene |  
                | Organism: | Mus spretus |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418354 |  
                | Assay Type: | Northern blot |  
                | Annotation Date: | 2010-01-21 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750321 |  
                |  |  
                | Stage: | TS21 |  
                | Assay Id: | MGI:4418355 |  
                | Age: | embryonic day 13.5 |  
                |  |  
                |  |  
                | Specimen Label: | E13.5 |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418354 |  
                | Assay Type: | Northern blot |  
                | Annotation Date: | 2010-01-21 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418355 |  
                | Age: | embryonic day 15.5 |  
                |  |  
                |  |  
                | Specimen Label: | E15.5 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418356 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2010-01-21 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750321 |  
                |  |  
                | Stage: | TS21 |  
                | Assay Id: | MGI:4418357 |  
                | Age: | embryonic day 13.5 |  
                |  |  
                |  |  
                | Specimen Label: | E13.5 |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418356 |  
                | Assay Type: | RT-PCR |  
                | Annotation Date: | 2010-01-21 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418357 |  
                | Age: | embryonic day 15.5 |  
                |  |  
                |  |  
                | Specimen Label: | E15.5 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1636317 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 10.5 |  
                | Image: | 5A |  
                | Note: | Expression is present in the developing alpha cells of the pancreas. |  
                | Specimen Label: | 5A |  
                | Detected: | true |  
                | Specimen Num: | 6 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Weak |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1636317 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 10.5 |  
                |  |  
                | Note: | Expression is almost completely ablated in the mutant. |  
                | Specimen Label: | Not shown |  
                | Detected: | true |  
                | Specimen Num: | 6 |  | • • • • • | 
          
              | GXD Expression | 
              
                |  |  
                | Assay Type: | In situ reporter (knock in) |  
                | Annotation Date: | 2021-04-16 |  
                | Strength: | Present |  
                | Sex: | Female |  
                | Emaps: | EMAPS:1737328 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:6692719 |  
                | Age: | postnatal adult |  
                | Image: | TCP_2460298 |  
                | Note: | kidney |  
                | Specimen Label: | TCP_2460298 |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Strong |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1619815 |  
                | Pattern: | Not Specified |  
                | Stage: | TS15 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 9.5 |  
                |  |  
                |  |  
                | Specimen Label: | Table S4 - E9.5 |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Strong |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1619819 |  
                | Pattern: | Not Specified |  
                | Stage: | TS19 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 11.5 |  
                |  |  
                |  |  
                | Specimen Label: | Table S4 - E11.5 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Strong |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1640519 |  
                | Pattern: | Non-Uniform |  
                | Stage: | TS19 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 11.5 |  
                |  |  
                | Note: | Staining is strong in the interdigital region and moderate in the antero-distal, antero-proximal, posterior-distal and posterior-proximal regions of the limb. |  
                | Specimen Label: | Table S4 - E11.5 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Moderate |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1680017 |  
                | Pattern: | Not Specified |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 10.5 |  
                |  |  
                | Note: | Staining is present in the olfactory placode. |  
                | Specimen Label: | Table S4 - E10.5 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Moderate |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1680019 |  
                | Pattern: | Not Specified |  
                | Stage: | TS19 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 11.5 |  
                |  |  
                | Note: | Staining is present in the olfactory placode. |  
                | Specimen Label: | Table S4 - E11.5 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Moderate |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1619419 |  
                | Pattern: | Not Specified |  
                | Stage: | TS19 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 11.5 |  
                |  |  
                | Note: | Staining is present in the otic pit. |  
                | Specimen Label: | Table S4 - E11.5 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Strong |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3270515 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS15 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 9.5 |  
                |  |  
                | Note: | Staining is present in the proximal limb. |  
                | Specimen Label: | Table S4 - E9.5 |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Moderate |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3270517 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 10.5 |  
                |  |  
                | Note: | Staining is present in the middle limb. |  
                | Specimen Label: | Table S4 - E10.5 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Strong |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3270519 |  
                | Pattern: | Non-Uniform |  
                | Stage: | TS19 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 11.5 |  
                |  |  
                | Note: | Staining is strong in the middle limb and moderate in the progress zone. |  
                | Specimen Label: | Table S4 - E11.5 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Strong |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1610517 |  
                | Pattern: | Not Specified |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 10.5 |  
                |  |  
                |  |  
                | Specimen Label: | Table S4 - E10.5 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Strong |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1684619 |  
                | Pattern: | Not Specified |  
                | Stage: | TS19 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 11.5 |  
                |  |  
                |  |  
                | Specimen Label: | Table S4 - E11.5 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750320 |  
                | Pattern: | Not Specified |  
                | Stage: | TS20 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 12.5 |  
                | Image: | S2 A |  
                | Note: | Expression is primarily present in non-dividing cells; only rarely is it present in dividing cells. |  
                | Specimen Label: | S2 A |  
                | Detected: | true |  
                | Specimen Num: | 13 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750321 |  
                | Pattern: | Not Specified |  
                | Stage: | TS21 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 13.5 |  
                | Image: | S2 B |  
                | Note: | Expression is primarily present in non-dividing cells; only rarely is it present in dividing cells. |  
                | Specimen Label: | S2 B |  
                | Detected: | true |  
                | Specimen Num: | 14 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                | Pattern: | Not Specified |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 15.5 |  
                | Image: | S2 C |  
                | Note: | Expression is primarily present in non-dividing cells; only rarely is it present in dividing cells. |  
                | Specimen Label: | S2 C |  
                | Detected: | true |  
                | Specimen Num: | 15 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750326 |  
                | Pattern: | Not Specified |  
                | Stage: | TS26 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 18.5 |  
                | Image: | S2 D |  
                | Note: | Expression is primarily present in non-dividing cells; only rarely is it present in dividing cells. |  
                | Specimen Label: | S2 D |  
                | Detected: | true |  
                | Specimen Num: | 16 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                | Pattern: | Not Specified |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 15.5 |  
                | Image: | 5B |  
                | Note: | Expression is present in the developing alpha cells of the pancreas. |  
                | Specimen Label: | 5B |  
                | Detected: | true |  
                | Specimen Num: | 7 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                | Pattern: | Not Specified |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 15.5 |  
                | Image: | 5C |  
                | Note: | Expression is present in the developing beta cells of the pancreas. |  
                | Specimen Label: | 5C |  
                | Detected: | true |  
                | Specimen Num: | 8 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750322 |  
                | Pattern: | Not Specified |  
                | Stage: | TS22 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 14.5 |  
                | Image: | 4B |  
                |  |  
                | Specimen Label: | 4B |  
                | Detected: | true |  
                | Specimen Num: | 10 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750322 |  
                | Pattern: | Not Specified |  
                | Stage: | TS22 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 14.5 |  
                | Image: | 4D |  
                | Note: | Expression in the mutant is the same as in wild type. |  
                | Specimen Label: | 4D |  
                | Detected: | true |  
                | Specimen Num: | 11 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750322 |  
                | Pattern: | Not Specified |  
                | Stage: | TS22 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 14.5 |  
                | Image: | 4F |  
                | Note: | Expression in the mutant is the same as in wild type. |  
                | Specimen Label: | 4F |  
                | Detected: | true |  
                | Specimen Num: | 12 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750322 |  
                | Pattern: | Not Specified |  
                | Stage: | TS22 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 14.5 |  
                | Image: | 4H |  
                | Note: | Expression in the mutant is the same as in wild type. |  
                | Specimen Label: | 4H |  
                | Detected: | true |  
                | Specimen Num: | 13 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                | Pattern: | Not Specified |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 15.5 |  
                | Image: | 3A |  
                |  |  
                | Specimen Label: | 3A |  
                | Detected: | true |  
                | Specimen Num: | 7 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                | Pattern: | Not Specified |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 15.5 |  
                | Image: | 3C |  
                |  |  
                | Specimen Label: | 3C |  
                | Detected: | true |  
                | Specimen Num: | 8 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                | Pattern: | Not Specified |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 15.5 |  
                | Image: | 3E |  
                |  |  
                | Specimen Label: | 3E |  
                | Detected: | true |  
                | Specimen Num: | 9 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 15.5 |  
                | Image: | 2E/F |  
                | Note: | Expression appears to be present in the developing islet cells of the pancreas. |  
                | Specimen Label: | 2E/F |  
                | Detected: | true |  
                | Specimen Num: | 5 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 15.5 |  
                | Image: | 2G |  
                | Note: | Expression appears to be present in the developing islet cells of the pancreas. |  
                | Specimen Label: | 2G |  
                | Detected: | true |  
                | Specimen Num: | 4 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Absent |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1750323 |  
                |  |  
                | Stage: | TS23 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 15.5 |  
                | Image: | 2H |  
                |  |  
                | Specimen Label: | 2H |  
                | Detected: | false |  
                | Specimen Num: | 5 |  | • • • • • | 
          
              | GXD Expression | 
              
                |  |  
                | Assay Type: | In situ reporter (knock in) |  
                | Annotation Date: | 2021-04-16 |  
                | Strength: | Present |  
                | Sex: | Male |  
                | Emaps: | EMAPS:1928728 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:6692719 |  
                | Age: | postnatal adult |  
                | Image: | TCP_2460297 |  
                |  |  
                | Specimen Label: | TCP_2460297 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Moderate |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1666917 |  
                | Pattern: | Not Specified |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 10.5 |  
                |  |  
                | Note: | Staining is present in the otic pit. |  
                | Specimen Label: | Table S4 - E10.5 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3292814 |  
                | Pattern: | Not Specified |  
                | Stage: | TS14 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 9.0 |  
                | Image: | 1B |  
                | Note: | There is broad expression in the gut endoderm. |  
                | Specimen Label: | 1B |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3292817 |  
                | Pattern: | Not Specified |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 10.5 |  
                | Image: | 1F |  
                |  |  
                | Specimen Label: | 1F |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3292728 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | postnatal adult |  
                | Image: | 5E |  
                | Note: | There was expression present in the beta cells. |  
                | Specimen Label: | 5E |  
                | Detected: | true |  
                | Specimen Num: | 10 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3292728 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | postnatal adult |  
                | Image: | 5D |  
                | Note: | There was expression present in the alpha cells. |  
                | Specimen Label: | 5D |  
                | Detected: | true |  
                | Specimen Num: | 9 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3292728 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | postnatal adult |  
                | Image: | 5F |  
                | Note: | Expression is present in delta cells. |  
                | Specimen Label: | 5F |  
                | Detected: | true |  
                | Specimen Num: | 11 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:3292728 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | postnatal adult |  
                | Image: | 5G |  
                | Note: | Expression is present in gamma cells. |  
                | Specimen Label: | 5G |  
                | Detected: | true |  
                | Specimen Num: | 12 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1706615 |  
                | Pattern: | Not Specified |  
                | Stage: | TS15 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 9.5 |  
                | Image: | 1D/E |  
                | Note: | Expression is present in the nascent pancreatic buds. |  
                | Specimen Label: | 1D/E |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1706617 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 10.5 |  
                | Image: | 1G |  
                | Note: | Expression appears to be present in the differentiating endocrine (islet) cells of the pancreas. |  
                | Specimen Label: | 1G |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1706617 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 10.5 |  
                | Image: | 1H |  
                | Note: | Expression appears to be present in the differentiating endocrine (islet) cells of the pancreas. |  
                | Specimen Label: | 1H |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418273 |  
                | Assay Type: | Immunohistochemistry |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1706617 |  
                | Pattern: | Regionally restricted |  
                | Stage: | TS17 |  
                | Assay Id: | MGI:4418318 |  
                | Age: | embryonic day 10.5 |  
                | Image: | 2B/C |  
                | Note: | Expression appears to be present in the developing islet cells of the pancreas. |  
                | Specimen Label: | 2B/C |  
                | Detected: | true |  
                | Specimen Num: | 4 |  | • • • • • | 
          
              | GXD Expression | 
              
                |  |  
                | Assay Type: | In situ reporter (knock in) |  
                | Annotation Date: | 2021-04-16 |  
                | Strength: | Present |  
                | Sex: | Female |  
                | Emaps: | EMAPS:1702128 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:6692719 |  
                | Age: | postnatal adult |  
                | Image: | UC Davis_1872018 |  
                |  |  
                | Specimen Label: | UC Davis_1872018 |  
                | Detected: | true |  
                | Specimen Num: | 2 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4418282 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-01-20 |  
                | Strength: | Present |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1606214 |  
                | Pattern: | Not Specified |  
                | Stage: | TS14 |  
                | Assay Id: | MGI:4418300 |  
                | Age: | embryonic day 9.0 |  
                | Image: | 1A |  
                | Note: | There is broad expression in the gut endoderm. |  
                | Specimen Label: | 1A |  
                | Detected: | true |  
                | Specimen Num: | 1 |  | • • • • • | 
          
              | GXD Expression | 
              
                |  |  
                | Assay Type: | In situ reporter (knock in) |  
                | Annotation Date: | 2021-04-16 |  
                | Strength: | Present |  
                | Sex: | Male |  
                | Emaps: | EMAPS:1929028 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:6692719 |  
                | Age: | postnatal adult |  
                | Image: | UC Davis_1872022 |  
                |  |  
                | Specimen Label: | UC Davis_1872022 |  
                | Detected: | true |  
                | Specimen Num: | 6 |  | • • • • • | 
          
              | GXD Expression | 
              
                |  |  
                | Assay Type: | In situ reporter (knock in) |  
                | Annotation Date: | 2021-04-16 |  
                | Strength: | Present |  
                | Sex: | Male |  
                | Emaps: | EMAPS:3276428 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:6692719 |  
                | Age: | postnatal adult |  
                | Image: | UC Davis_1872020 |  
                |  |  
                | Specimen Label: | UC Davis_1872020 |  
                | Detected: | true |  
                | Specimen Num: | 4 |  | • • • • • | 
          
              | GXD Expression | 
              
                |  |  
                | Assay Type: | In situ reporter (knock in) |  
                | Annotation Date: | 2021-04-16 |  
                | Strength: | Present |  
                | Sex: | Male |  
                | Emaps: | EMAPS:3276428 |  
                | Pattern: | Not Specified |  
                | Stage: | TS28 |  
                | Assay Id: | MGI:6692719 |  
                | Age: | postnatal adult |  
                | Image: | UC Davis_1872021 |  
                |  |  
                | Specimen Label: | UC Davis_1872021 |  
                | Detected: | true |  
                | Specimen Num: | 5 |  | • • • • • | 
          
              | GXD Expression | 
              
                | Probe: | MGI:4845473 |  
                | Assay Type: | RNA in situ |  
                | Annotation Date: | 2010-12-22 |  
                | Strength: | Moderate |  
                | Sex: | Not Specified |  
                | Emaps: | EMAPS:1618419 |  
                | Pattern: | Not Specified |  
                | Stage: | TS19 |  
                | Assay Id: | MGI:4848998 |  
                | Age: | embryonic day 11.5 |  
                |  |  
                |  |  
                | Specimen Label: | Table S4 - E11.5 |  
                | Detected: | true |  
                | Specimen Num: | 3 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Magnuson MA |  
                | Year: | 2013 |  
                | Journal: | Cell Metab |  
                | Title: | Pancreas-specific Cre driver lines and considerations for their prudent use. |  
                | Volume: | 18 |  
                | Issue: | 1 |  
                | Pages: | 9-20 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Serafimidis I |  
                | Year: | 2011 |  
                | Journal: | Mol Cell Biol |  
                | Title: | G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesis. |  
                | Volume: | 31 |  
                | Issue: | 22 |  
                | Pages: | 4442-53 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Zinina VV |  
                | Year: | 2023 |  
                | Journal: | Cells |  
                | Title: | TCF7L1 Controls the Differentiation of Tuft Cells in Mouse Small Intestine. |  
                | Volume: | 12 |  
                | Issue: | 11 |  
                |  |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Churchill AJ |  
                | Year: | 2017 |  
                | Journal: | Elife |  
                | Title: | Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development. |  
                | Volume: | 6 |  
                |  |  
                |  |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Ohta Y |  
                | Year: | 2011 |  
                | Journal: | Diabetes |  
                | Title: | Convergence of the insulin and serotonin programs in the pancreatic β-cell. |  
                | Volume: | 60 |  
                | Issue: | 12 |  
                | Pages: | 3208-16 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Abdellatif AM |  
                | Year: | 2016 |  
                | Journal: | PLoS One |  
                | Title: | β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development. |  
                | Volume: | 11 |  
                | Issue: | 2 |  
                | Pages: | e0150010 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Ansarullah |  
                | Year: | 2021 |  
                | Journal: | Nature |  
                | Title: | Inceptor counteracts insulin signalling in β-cells to control glycaemia. |  
                | Volume: | 590 |  
                | Issue: | 7845 |  
                | Pages: | 326-331 |  | • • • • • | 
          
              | Publication | 
              
                | First Author: | Yokoyama S |  
                | Year: | 2009 |  
                | Journal: | Dev Cell |  
                | Title: | A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |  
                | Volume: | 17 |  
                | Issue: | 6 |  
                | Pages: | 836-48 |  | • • • • • |