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Search results 1 to 79 out of 79 for Rgl3

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Hits by Strain

Hits by Category

Type Details Score
Gene
57139 | RGL3
Type: gene
Organism: human
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Gene
714496 | RGL3
Type: gene
Organism: macaque, rhesus
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Gene
100485337 | rgl3
Type: gene
Organism: frog, western clawed
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Gene
484942 | RGL3
Type: gene
Organism: dog, domestic
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Gene
455730 | RGL3
Type: gene
Organism: chimpanzee
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Gene
785402 | RGL3
Type: gene
Organism: cattle
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Protein Coding Gene
MGI:1918996 | Rgl3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030750 | RGL3
Type: Family
Description: RGL3 (RalGDS-like 3) belongs to the Ral GDP dissociation stimulator (RalGDS) family []. RGL3 functions as an exchange factor for Ral and may serve as a downstream effector for both Rit and Ras [, ].RalGDS family members can act both as Ras effectors and as guanine nucleotide exchange factors (GEFs) for Ral. They act downstream of Ras and bind to the GTP-bound active form of Ras or Ras family members. They also promote the GDP to GTP exchange for Ral small GTPase, member of the Ras family []. Due to their double action, the RalGDS proteins bridge Ras and Ral [].
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Publication
10869344 | J:64313
First Author: Shao H
Year: 2000
Journal: J Biol Chem
Title: A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras.
Volume: 275
Issue: 35
Pages: 26914-24
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Publication
11313946 | -
First Author: Ehrhardt GR
Year: 2001
Journal: Oncogene
Title: A novel potential effector of M-Ras and p21 Ras negatively regulates p21 Ras-mediated gene induction and cell growth.
Volume: 20
Issue: 2
Pages: 188-97
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Protein
A0A1L1ST67
Organism: Mus musculus/domesticus
Length: 87  
Fragment?: false
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Publication
10760592 | -
First Author: Sood R
Year: 2000
Journal: Biochim Biophys Acta
Title: The human RGL (RalGDS-like) gene: cloning, expression analysis and genomic organization.
Volume: 1491
Issue: 1-3
Pages: 285-8
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Publication
20478380 | -
First Author: Ferro E
Year: 2010
Journal: Cell Signal
Title: RalGDS family members couple Ras to Ral signalling and that's not all.
Volume: 22
Issue: 12
Pages: 1804-10
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Publication
9099691 | -
First Author: Murai H
Year: 1997
Journal: J Biol Chem
Title: Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral.
Volume: 272
Issue: 16
Pages: 10483-90
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Protein
Q3UYI5
Organism: Mus musculus/domesticus
Length: 709  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0031891 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034471 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034449 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034375 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034440 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034152 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1918996 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034270 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034981 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014757 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033014 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:2448719
Assay Type: Northern blot
Annotation Date: 2003-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2448722
Age: postnatal
Image: 2
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:2448719
Assay Type: Northern blot
Annotation Date: 2003-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2448722
Age: postnatal
Image: 2
Specimen Label: Brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:2448719
Assay Type: Northern blot
Annotation Date: 2003-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2448722
Age: postnatal
Image: 2
Specimen Label: Spleen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:2448719
Assay Type: Northern blot
Annotation Date: 2003-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2448722
Age: postnatal
Image: 2
Specimen Label: Lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2448719
Assay Type: Northern blot
Annotation Date: 2003-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2448722
Age: postnatal
Image: 2
Specimen Label: Liver
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:2448719
Assay Type: Northern blot
Annotation Date: 2003-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2448722
Age: postnatal
Image: 2
Specimen Label: Skeletal Muscle
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:2448719
Assay Type: Northern blot
Annotation Date: 2003-01-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2448722
Age: postnatal
Image: 2
Specimen Label: Kidney
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:2448719
Assay Type: Northern blot
Annotation Date: 2003-01-30
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2448722
Age: postnatal
Image: 2
Specimen Label: Testis
Detected: true
Specimen Num: 8
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Allele
Rgl3<em2Smoc> | MGI:7292035
Name: ral guanine nucleotide dissociation stimulator-like 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6771114 | C57BL/6-Rgl3<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Rgl3<em1Smoc> | MGI:7292034
Name: ral guanine nucleotide dissociation stimulator-like 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6771113 | C57BL/6J-Rgl3<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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HT Experiment
GSE117394 | Molecular analysis of the midbrain dopaminergic niche during neurogenesis
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
18540861 | -
First Author: Ferro E
Year: 2008
Journal: Biochem J
Title: G-protein binding features and regulation of the RalGDS family member, RGL2.
Volume: 415
Issue: 1
Pages: 145-54
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Publication
17344481 | J:127490
First Author: Takaya A
Year: 2007
Journal: Mol Biol Cell
Title: R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes.
Volume: 18
Issue: 5
Pages: 1850-60
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Protein Domain
IPR030749 | RGL2
Type: Family
Description: RGL2 (RalGDS-like 2) belongs to the Ral GDP dissociation stimulator (RalGDS) family []. The C-terminal fragment (Ras/Rap-binding domain) of RGL2 interacts specifically with Ras family proteins that share identical effector domain sequences with Rap1 (H-Ras, R-Ras, Tc21). The binding ability of RGL2 to H-Ras can be regulated through a PKA phosphorylation site identified in this C-terminal domain []. This phoshorylation site is only conserved in the RGL2 murine orthologue, Rlf, but not in RalGDS, RGL and RGL3 []. RGL2 is a guanine nucleotide exchange factor (GEF) for RalA, which plays an important role in the assembly of the exocyst complex. R-Ras regulates exocytosis by RGL2/Rlf-mediated activation of RalA on endosomes [].RalGDS family members can act both as Ras effectors and as guanine nucleotide exchange factors (GEFs) for Ral. They act downstream of Ras and bind to the GTP-bound active form of Ras or Ras family members. They also promote the GDP to GTP exchange for Ral small GTPase, member of the Ras family []. Due to their double action, the RalGDS proteins bridge Ras and Ral [].
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Protein
A0A3Q4EGY1
Organism: Mus musculus/domesticus
Length: 63  
Fragment?: true
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Protein
G3UZ21
Organism: Mus musculus/domesticus
Length: 314  
Fragment?: true
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Protein
Q61193
Organism: Mus musculus/domesticus
Length: 778  
Fragment?: false
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Protein
A0A068BD34
Organism: Mus musculus/domesticus
Length: 778  
Fragment?: false
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