|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 415 for Rictor

<< First    < Previous  |  Next >    Last >>
0.055s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Julien LA
Year: 2010
Journal: Mol Cell Biol
Title: mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
Volume: 30
Issue: 4
Pages: 908-21
Publication
First Author: Dibble CC
Year: 2009
Journal: Mol Cell Biol
Title: Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1.
Volume: 29
Issue: 21
Pages: 5657-70
Publication
First Author: Tang F
Year: 2012
Journal: J Immunol
Title: A critical role for Rictor in T lymphopoiesis.
Volume: 189
Issue: 4
Pages: 1850-7
Publication
First Author: Bashir T
Year: 2012
Journal: PLoS One
Title: Conditional astroglial Rictor overexpression induces malignant glioma in mice.
Volume: 7
Issue: 10
Pages: e47741
Publication
First Author: Shiota C
Year: 2006
Journal: Dev Cell
Title: Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.
Volume: 11
Issue: 4
Pages: 583-9
Publication
First Author: Zhu Y
Year: 2019
Journal: Cell Death Differ
Title: Superhero Rictor promotes cellular differentiation of mouse embryonic stem cells.
Volume: 26
Issue: 5
Pages: 958-968
Publication  
First Author: Kaska S
Year: 2017
Journal: Neuropharmacology
Title: Deletion of Rictor in catecholaminergic neurons alters locomotor activity and ingestive behavior.
Volume: 117
Pages: 158-170
Publication
First Author: Zhang Y
Year: 2014
Journal: PLoS One
Title: Rictor is required for early B cell development in bone marrow.
Volume: 9
Issue: 8
Pages: e103970
Publication
First Author: Gao D
Year: 2010
Journal: Mol Cell
Title: Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.
Volume: 39
Issue: 5
Pages: 797-808
Publication
First Author: Lee K
Year: 2013
Journal: Blood
Title: Requirement for Rictor in homeostasis and function of mature B lymphoid cells.
Volume: 122
Issue: 14
Pages: 2369-79
Publication
First Author: Thomanetz V
Year: 2013
Journal: J Cell Biol
Title: Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology.
Volume: 201
Issue: 2
Pages: 293-308
Publication
First Author: Bhattacharya I
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Rictor in perivascular adipose tissue controls vascular function by regulating inflammatory molecule expression.
Volume: 33
Issue: 9
Pages: 2105-11
Publication
First Author: Drägert K
Year: 2015
Journal: Hypertension
Title: Deletion of Rictor in brain and fat alters peripheral clock gene expression and increases blood pressure.
Volume: 66
Issue: 2
Pages: 332-9
Publication
First Author: Kumar A
Year: 2008
Journal: Mol Cell Biol
Title: Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity.
Volume: 28
Issue: 1
Pages: 61-70
Publication  
First Author: Sun W
Year: 2016
Journal: Bone
Title: Rictor is required for optimal bone accrual in response to anti-sclerostin therapy in the mouse.
Volume: 85
Pages: 1-8
Publication  
First Author: Aimi F
Year: 2015
Journal: Sci Rep
Title: Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult.
Volume: 5
Pages: 17705
Publication
First Author: Godale CM
Year: 2022
Journal: J Mol Neurosci
Title: Impact of Raptor and Rictor Deletion on Hippocampal Pathology Following Status Epilepticus.
Volume: 72
Issue: 6
Pages: 1243-1258
Publication
First Author: Siuta MA
Year: 2010
Journal: PLoS Biol
Title: Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice.
Volume: 8
Issue: 6
Pages: e1000393
Publication
First Author: Fang Y
Year: 2017
Journal: Leukemia
Title: Rictor has a pivotal role in maintaining quiescence as well as stemness of leukemia stem cells in MLL-driven leukemia.
Volume: 31
Issue: 2
Pages: 414-422
Publication
First Author: Bercury KK
Year: 2014
Journal: J Neurosci
Title: Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.
Volume: 34
Issue: 13
Pages: 4466-80
Publication
First Author: Carson RP
Year: 2013
Journal: Hum Mol Genet
Title: Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.
Volume: 22
Issue: 1
Pages: 140-52
Publication
First Author: Parker SJ
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice.
Volume: 315
Issue: 5
Pages: H1112-H1126
Publication
First Author: Huang L
Year: 2017
Journal: PLoS Biol
Title: Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin.
Volume: 15
Issue: 8
Pages: e2001750
Publication
First Author: Festuccia WT
Year: 2014
Journal: PLoS One
Title: Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide.
Volume: 9
Issue: 4
Pages: e95432
Publication
First Author: Bai S
Year: 2018
Journal: Mol Hum Reprod
Title: A germline-specific role for the mTORC2 component Rictor in maintaining spermatogonial differentiation and intercellular adhesion in mouse testis.
Volume: 24
Issue: 5
Pages: 244-259
Publication
First Author: Carr TD
Year: 2015
Journal: Carcinogenesis
Title: Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Volume: 36
Issue: 4
Pages: 487-97
Publication
First Author: Kumar A
Year: 2010
Journal: Diabetes
Title: Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.
Volume: 59
Issue: 6
Pages: 1397-406
Publication
First Author: Singh BK
Year: 2016
Journal: J Biol Chem
Title: Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
Volume: 291
Issue: 1
Pages: 198-214
Publication
First Author: Rosner M
Year: 2008
Journal: Hum Mol Genet
Title: Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.
Volume: 17
Issue: 19
Pages: 2934-48
Publication
First Author: Sarbassov DD
Year: 2004
Journal: Curr Biol
Title: Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Volume: 14
Issue: 14
Pages: 1296-302
Publication
First Author: Yang Q
Year: 2006
Journal: Genes Dev
Title: Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity.
Volume: 20
Issue: 20
Pages: 2820-32
Publication  
First Author: Babaev VR
Year: 2018
Journal: Front Immunol
Title: Loss of Rictor in Monocyte/Macrophages Suppresses Their Proliferation and Viability Reducing Atherosclerosis in LDLR Null Mice.
Volume: 9
Pages: 215
Publication
First Author: Guertin DA
Year: 2006
Journal: Dev Cell
Title: Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
Volume: 11
Issue: 6
Pages: 859-71
Publication
First Author: Guertin DA
Year: 2009
Journal: Cancer Cell
Title: mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Volume: 15
Issue: 2
Pages: 148-59
Publication
First Author: Kocalis HE
Year: 2014
Journal: Mol Metab
Title: Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis.
Volume: 3
Issue: 4
Pages: 394-407
Publication
First Author: Yu D
Year: 2019
Journal: Cell Rep
Title: Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension.
Volume: 29
Issue: 1
Pages: 236-248.e3
Publication
First Author: Mazei-Robison MS
Year: 2011
Journal: Neuron
Title: Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons.
Volume: 72
Issue: 6
Pages: 977-90
Publication
First Author: Hsiao WY
Year: 2020
Journal: Cell Rep
Title: The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development.
Volume: 33
Issue: 1
Pages: 108223
Publication
First Author: Cortada M
Year: 2023
Journal: iScience
Title: mTORC2 regulates auditory hair cell structure and function.
Volume: 26
Issue: 9
Pages: 107687
Publication
First Author: Prevot N
Year: 2015
Journal: J Immunol
Title: Mammalian target of rapamycin complex 2 regulates invariant NKT cell development and function independent of promyelocytic leukemia zinc-finger.
Volume: 194
Issue: 1
Pages: 223-30
Publication
First Author: Huang W
Year: 2013
Journal: Nat Neurosci
Title: mTORC2 controls actin polymerization required for consolidation of long-term memory.
Volume: 16
Issue: 4
Pages: 441-8
Publication  
First Author: Liu DM
Year: 2016
Journal: Bone
Title: Rictor/mTORC2 loss in osteoblasts impairs bone mass and strength.
Volume: 90
Pages: 50-8
Publication
First Author: Castro-Martinez F
Year: 2021
Journal: Am J Pathol
Title: Rictor/Mammalian Target of Rapamycin Complex 2 Signaling Protects Colonocytes from Apoptosis and Prevents Epithelial Barrier Breakdown.
Volume: 191
Issue: 9
Pages: 1537-1549
Publication
First Author: Xie Y
Year: 2017
Journal: Biochim Biophys Acta
Title: The mTORC2/PKC pathway sustains compensatory insulin secretion of pancreatic β cells in response to metabolic stress.
Volume: 1861
Issue: 8
Pages: 2039-2047
Publication
First Author: Lamming DW
Year: 2014
Journal: FASEB J
Title: Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2).
Volume: 28
Issue: 1
Pages: 300-15
Publication
First Author: Li J
Year: 2014
Journal: Kidney Int
Title: Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury.
Volume: 86
Issue: 1
Pages: 86-102
Publication
First Author: Yuan M
Year: 2012
Journal: J Biol Chem
Title: Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2.
Volume: 287
Issue: 35
Pages: 29579-88
Publication
First Author: Ren J
Year: 2017
Journal: J Pathol
Title: Rictor/mammalian target of rapamycin complex 2 promotes macrophage activation and kidney fibrosis.
Volume: 242
Issue: 4
Pages: 488-499
Publication
First Author: Morrison Joly M
Year: 2016
Journal: Cancer Res
Title: Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.
Volume: 76
Issue: 16
Pages: 4752-64
Publication
First Author: Shu L
Year: 2009
Journal: Mol Cell Biol
Title: The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
Volume: 29
Issue: 17
Pages: 4691-700
Publication
First Author: Li J
Year: 2015
Journal: Kidney Int
Title: Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis.
Volume: 88
Issue: 3
Pages: 515-27
Publication
First Author: Zhang L
Year: 2016
Journal: Cell Rep
Title: Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner.
Volume: 14
Issue: 5
Pages: 1206-1217
Publication
First Author: Sklarz T
Year: 2017
Journal: Eur J Immunol
Title: mTORC2 regulates multiple aspects of NKT-cell development and function.
Volume: 47
Issue: 3
Pages: 516-526
Publication
First Author: Morrison MM
Year: 2015
Journal: PLoS Genet
Title: mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
Volume: 11
Issue: 7
Pages: e1005291
Publication
First Author: Qin B
Year: 2018
Journal: Cell Physiol Biochem
Title: MicroRNA-142-3p Induces Atherosclerosis-Associated Endothelial Cell Apoptosis by Directly Targeting Rictor.
Volume: 47
Issue: 4
Pages: 1589-1603
Publication
First Author: Kroczynska B
Year: 2016
Journal: J Biol Chem
Title: Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses.
Volume: 291
Issue: 5
Pages: 2389-96
Publication
First Author: Bentzinger CF
Year: 2008
Journal: Cell Metab
Title: Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy.
Volume: 8
Issue: 5
Pages: 411-24
Publication    
First Author: Yang C
Year: 2018
Journal: Elife
Title: mTORC1 and mTORC2 differentially promote natural killer cell development.
Volume: 7
Publication  
First Author: Tang Y
Year: 2016
Journal: Nat Commun
Title: Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
Volume: 7
Pages: 11365
Publication  
First Author: Hallowell RW
Year: 2017
Journal: Nat Commun
Title: mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis.
Volume: 8
Pages: 14208
Publication
First Author: Sciarretta S
Year: 2015
Journal: Cell Rep
Title: mTORC2 regulates cardiac response to stress by inhibiting MST1.
Volume: 11
Issue: 1
Pages: 125-36
Publication  
First Author: Katholnig K
Year: 2019
Journal: JCI Insight
Title: Inactivation of mTORC2 in macrophages is a signature of colorectal cancer that promotes tumorigenesis.
Volume: 4
Issue: 20
Publication
First Author: Hagan GN
Year: 2008
Journal: Mol Cell Biol
Title: A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes.
Volume: 28
Issue: 13
Pages: 4215-26
Publication
First Author: Grier MD
Year: 2017
Journal: PLoS One
Title: Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.
Volume: 12
Issue: 11
Pages: e0188417
Publication  
First Author: Wong C
Year: 2022
Journal: J Clin Invest
Title: mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation.
Volume: 132
Issue: 15
Publication  
First Author: Chen WY
Year: 2017
Journal: Sci Rep
Title: Heterogeneous nuclear ribonucleoprotein M associates with mTORC2 and regulates muscle differentiation.
Volume: 7
Pages: 41159
Publication
First Author: Dahl KD
Year: 2023
Journal: J Neurosci
Title: mTORC2 Loss in Oligodendrocyte Progenitor Cells Results in Regional Hypomyelination in the Central Nervous System.
Volume: 43
Issue: 4
Pages: 540-558
Publication
First Author: Wang F
Year: 2018
Journal: Nat Commun
Title: Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function.
Volume: 9
Issue: 1
Pages: 4874
Publication
First Author: Gerlach BD
Year: 2021
Journal: Cell Metab
Title: Efferocytosis induces macrophage proliferation to help resolve tissue injury.
Volume: 33
Issue: 12
Pages: 2445-2463.e8
Publication
First Author: Magee JA
Year: 2012
Journal: Cell Stem Cell
Title: Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression.
Volume: 11
Issue: 3
Pages: 415-28
Publication
First Author: Lamming DW
Year: 2012
Journal: Science
Title: Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Volume: 335
Issue: 6076
Pages: 1638-43
Publication
First Author: Wang S
Year: 2015
Journal: Mol Cell Biol
Title: Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
Volume: 35
Issue: 7
Pages: 1299-313
Publication
First Author: Zhang Y
Year: 2021
Journal: FASEB J
Title: Rictor/mTORC2 is involved in endometrial receptivity by regulating epithelial remodeling.
Volume: 35
Issue: 7
Pages: e21731
Publication
First Author: Hua C
Year: 2014
Journal: Exp Hematol
Title: Rictor/mammalian target of rapamycin 2 regulates the development of Notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3.
Volume: 42
Issue: 12
Pages: 1031-40.e1-4
Publication      
First Author: Castro E
Year: 2021
Journal: Am J Physiol Endocrinol Metab
Title: Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice.
Publication
First Author: Chen Z
Year: 2015
Journal: J Biol Chem
Title: Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure.
Volume: 290
Issue: 10
Pages: 6387-96
Publication
First Author: Cybulski N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: mTOR complex 2 in adipose tissue negatively controls whole-body growth.
Volume: 106
Issue: 24
Pages: 9902-7
Publication
First Author: Tassone B
Year: 2017
Journal: Cell Death Differ
Title: Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.
Volume: 24
Issue: 4
Pages: 731-746
Publication
First Author: Le Bacquer O
Year: 2013
Journal: J Endocrinol
Title: mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
Volume: 216
Issue: 1
Pages: 21-9
Publication
First Author: Zhang Z
Year: 2012
Journal: Mol Cell Biochem
Title: mTOR-rictor is the Ser473 kinase for AKT1 in mouse one-cell stage embryos.
Volume: 361
Issue: 1-2
Pages: 249-57
Publication
First Author: Ding X
Year: 2020
Journal: J Allergy Clin Immunol
Title: Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation.
Volume: 145
Issue: 1
Pages: 283-300.e8
Publication
First Author: Jung SM
Year: 2019
Journal: Mol Cell
Title: Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Volume: 75
Issue: 4
Pages: 807-822.e8
Publication
First Author: Charbonnier LM
Year: 2019
Journal: Nat Immunol
Title: Functional reprogramming of regulatory T cells in the absence of Foxp3.
Volume: 20
Issue: 9
Pages: 1208-1219
Publication
First Author: Charbonnier LM
Year: 2015
Journal: Nat Immunol
Title: Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling.
Volume: 16
Issue: 11
Pages: 1162-73
Publication
First Author: Lebrun-Julien F
Year: 2014
Journal: J Neurosci
Title: Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination.
Volume: 34
Issue: 25
Pages: 8432-48
Publication
First Author: Hung CM
Year: 2014
Journal: Cell Rep
Title: Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.
Volume: 8
Issue: 1
Pages: 256-71
Publication
First Author: Micevic G
Year: 2016
Journal: Cell Rep
Title: DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR.
Volume: 14
Issue: 9
Pages: 2180-2192
Publication
First Author: Hagiwara A
Year: 2012
Journal: Cell Metab
Title: Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
Volume: 15
Issue: 5
Pages: 725-38
Publication
First Author: Gui Y
Year: 2018
Journal: J Biol Chem
Title: Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis.
Volume: 293
Issue: 42
Pages: 16364-16375
Publication
First Author: Risson V
Year: 2009
Journal: J Cell Biol
Title: Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.
Volume: 187
Issue: 6
Pages: 859-74
Publication
First Author: Zhao X
Year: 2014
Journal: Mol Cell Biol
Title: Phosphoinositide-dependent kinase 1 and mTORC2 synergistically maintain postnatal heart growth and heart function in mice.
Volume: 34
Issue: 11
Pages: 1966-75