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Search results 1 to 93 out of 93 for Rimbp2

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
23504 | RIMBP2
Type: gene
Organism: human
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Gene
718140 | RIMBP2
Type: gene
Organism: macaque, rhesus
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Gene
780347 | rimbp2
Type: gene
Organism: frog, western clawed
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Gene
266780 | Rimbp2
Type: gene
Organism: rat
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Gene
467161 | RIMBP2
Type: gene
Organism: chimpanzee
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Gene
527119 | RIMBP2
Type: gene
Organism: cattle
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Gene
100856418 | RIMBP2
Type: gene
Organism: dog, domestic
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Gene
374105 | RIMBP2
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:2443235 | Rimbp2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0027776 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030121 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030022 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030098 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443235 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029785 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029935 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029891 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030024 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030592 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029298 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024356 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028775 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
34353898 | J:310209
First Author: Butola T
Year: 2021
Journal: J Neurosci
Title: RIM-Binding Protein 2 Organizes Ca2+ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse.
Volume: 41
Issue: 37
Pages: 7742-7767
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Publication
27671655 | J:238503
First Author: Grauel MK
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.
Volume: 113
Issue: 41
Pages: 11615-11620
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Publication
31535974 | J:283753
   
First Author: Brockmann MM
Year: 2019
Journal: Elife
Title: RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses.
Volume: 8
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Publication
31848688 | J:299829
First Author: Ortner NJ
Year: 2020
Journal: Pflugers Arch
Title: RBP2 stabilizes slow Cav1.3 Ca2+ channel inactivation properties of cochlear inner hair cells.
Volume: 472
Issue: 1
Pages: 3-25
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Publication
26402606 | J:227659
First Author: Acuna C
Year: 2015
Journal: Neuron
Title: RIM-BPs Mediate Tight Coupling of Action Potentials to Ca(2+)-Triggered Neurotransmitter Release.
Volume: 87
Issue: 6
Pages: 1234-47
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Publication
29967030 | J:323964
 
First Author: Sclip A
Year: 2018
Journal: EMBO J
Title: RIM-binding proteins recruit BK-channels to presynaptic release sites adjacent to voltage-gated Ca2+-channels.
Volume: 37
Issue: 16
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Publication
28874522 | J:253627
First Author: Luo F
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Efficient stimulus-secretion coupling at ribbon synapses requires RIM-binding protein tethering of L-type Ca2+ channels.
Volume: 114
Issue: 38
Pages: E8081-E8090
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Publication
33539324 | J:307312
 
First Author: Mencacci NE
Year: 2021
Journal: J Clin Invest
Title: Biallelic variants in TSPOAP1, encoding the active-zone protein RIMBP1, cause autosomal recessive dystonia.
Volume: 131
Issue: 7
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Publication
32755572 | J:306464
First Author: Brockmann MM
Year: 2020
Journal: Cell Rep
Title: A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release.
Volume: 32
Issue: 5
Pages: 107960
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Publication
27537484 | J:308684
First Author: Acuna C
Year: 2016
Journal: Neuron
Title: How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs.
Volume: 91
Issue: 4
Pages: 792-807
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Publication
34767769 | J:324135
First Author: Banerjee A
Year: 2022
Journal: Neuron
Title: Molecular and functional architecture of striatal dopamine release sites.
Volume: 110
Issue: 2
Pages: 248-265.e9
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Publication
31927188 | J:287257
 
First Author: Ingham NJ
Year: 2020
Journal: Hear Res
Title: Functional analysis of candidate genes from genome-wide association studies of hearing.
Volume: 387
Pages: 107879
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Publication
17124501 | J:119934
First Author: Schoch S
Year: 2006
Journal: EMBO J
Title: Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.
Volume: 25
Issue: 24
Pages: 5852-63
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
28510727 | J:243499
First Author: Aikawa T
Year: 2017
Journal: Hum Mol Genet
Title: Alternative splicing in the C-terminal tail of Cav2.1 is essential for preventing a neurological disease in mice.
Volume: 26
Issue: 16
Pages: 3094-3104
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Publication
9915832 | -
First Author: Galiègue S
Year: 1999
Journal: J Biol Chem
Title: Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptor.
Volume: 274
Issue: 5
Pages: 2938-52
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Protein
F7CD74
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: true
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Protein Domain
IPR040325 | RIMBP1/2/3
Type: Family
Description: Proteins in this family contain SH3 and fibronectin type III (FN3) domains, with the FN3 domains inserted within the SH3 domains. Members include peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1, TSPOAP1 or RIMBP1, also known as RIMS-binding protein 1 or TSPO-associated protein 1) and RIMS-binding protein 2 (RIMBP2). PRAX-1 interacts with the peripheral benzodiazepine receptor []. RIMBP2 interacts with subunits of the voltage-gated Ca(2+) channels [].RIMs binding proteins (RBPs, RIM-BPs) associate with calcium channels present in photoreceptors, neurons, and hair cells; they interact simultaneously with specific calcium channel subunits, and active zone proteins, RIM1 and RIM2 []. RIMs are part of the matrix at the presynaptic active zone and are associated with synaptic vesicles through their interaction with the small GTPase Rab3 []. RIM-BPs play a role in regulating synaptic transmission by serving as adaptors and linking calcium channels with the synaptic vesicle release machinery []. RIM-BPs contain three SH3 domains and two to three fibronectin III repeats. Invertebrates contain one, while vertebrates contain at least two RIM-BPs, RIM-BP1 and RIM-BP2. RIM-BP1 is also called peripheral-type benzodiazapine receptor associated protein 1 (PRAX-1). Mammals contain a third protein, RIM-BP3 []. RIM-BP1 and RIM-BP2 are predominantly expressed in the brain where they display overlapping but distinct expression patterns, while RIM-BP3 is almost exclusively expressed in the testis and is essential in spermiogenesis []. The SH3 domains of RIM-BPs bind to the PxxP motifs of RIM1, RIM2, and L-type (alpha1D) and N-type (alpha1B) calcium channel subunits [].
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Protein
A0A0G2JEC0
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: true
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Publication
19091768 | J:144218
First Author: Zhou J
Year: 2009
Journal: Development
Title: RIM-BP3 is a manchette-associated protein essential for spermiogenesis.
Volume: 136
Issue: 3
Pages: 373-82
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Publication
11988172 | -
First Author: Hibino H
Year: 2002
Journal: Neuron
Title: RIM binding proteins (RBPs) couple Rab3-interacting molecules (RIMs) to voltage-gated Ca(2+) channels.
Volume: 34
Issue: 3
Pages: 411-23
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Publication
17855024 | -
First Author: Mittelstaedt T
Year: 2007
Journal: Gene
Title: Structure and evolution of RIM-BP genes: identification of a novel family member.
Volume: 403
Issue: 1-2
Pages: 70-9
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Publication
10748113 | J:72471
First Author: Wang Y
Year: 2000
Journal: J Biol Chem
Title: The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins.
Volume: 275
Issue: 26
Pages: 20033-44
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Publication
22174254 | -
First Author: Liu KS
Year: 2011
Journal: Science
Title: RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release.
Volume: 334
Issue: 6062
Pages: 1565-9
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Protein
Q5XJV9
Organism: Mus musculus/domesticus
Length: 465  
Fragment?: true
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Protein
F7AUI0
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: true
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Protein
Q6NZG5
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
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Protein
F6WV49
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: true
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Protein
Q80U40
Organism: Mus musculus/domesticus
Length: 1072  
Fragment?: false
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Protein
Q7TNF8
Organism: Mus musculus/domesticus
Length: 1846  
Fragment?: false
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Protein
Q3V0F0
Organism: Mus musculus/domesticus
Length: 1606  
Fragment?: false
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Protein
D3YXR8
Organism: Mus musculus/domesticus
Length: 1079  
Fragment?: false
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Protein
A0A0G2JGW5
Organism: Mus musculus/domesticus
Length: 1004  
Fragment?: false
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Protein
Q5NCP6
Organism: Mus musculus/domesticus
Length: 1786  
Fragment?: false
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Protein
A0A0G2JFB0
Organism: Mus musculus/domesticus
Length: 1071  
Fragment?: false
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Protein
A0A571BDA2
Organism: Mus musculus/domesticus
Length: 1291  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom