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Search results 1 to 100 out of 330 for Rock1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
MGI Directed Relationship Property
Name: Non-mouse_Gene_Symbol
Value: ROCK1
Publication
First Author: Lee DH
Year: 2009
Journal: J Biol Chem
Title: Targeted disruption of ROCK1 causes insulin resistance in vivo.
Volume: 284
Issue: 18
Pages: 11776-80
Publication
First Author: Noma K
Year: 2008
Journal: J Clin Invest
Title: ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.
Volume: 118
Issue: 5
Pages: 1632-44
Publication
First Author: Lee SH
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance.
Volume: 306
Issue: 3
Pages: E332-43
Publication
First Author: Surma M
Year: 2014
Journal: PLoS One
Title: ROCK1 deficiency enhances protective effects of antioxidants against apoptosis and cell detachment.
Volume: 9
Issue: 3
Pages: e90758
Publication
First Author: Huang H
Year: 2013
Journal: Endocrinology
Title: ROCK1 in AgRP neurons regulates energy expenditure and locomotor activity in male mice.
Volume: 154
Issue: 10
Pages: 3660-70
Publication  
First Author: Greathouse KM
Year: 2019
Journal: Behav Brain Res
Title: Fasudil or genetic depletion of ROCK1 or ROCK2 induces anxiety-like behaviors.
Volume: 373
Pages: 112083
Publication  
First Author: Gurkar AU
Year: 2013
Journal: Nat Commun
Title: Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.
Volume: 4
Pages: 2189
Publication
First Author: Shi J
Year: 2008
Journal: J Mol Cell Cardiol
Title: Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy.
Volume: 44
Issue: 3
Pages: 551-60
Publication  
First Author: Zhou X
Year: 2016
Journal: Sci Rep
Title: ROCK1 reduces mitochondrial content and irisin production in muscle suppressing adipocyte browning and impairing insulin sensitivity.
Volume: 6
Pages: 29669
Publication
First Author: Zhang YM
Year: 2006
Journal: FASEB J
Title: Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis.
Volume: 20
Issue: 7
Pages: 916-25
Publication
First Author: Vemula S
Year: 2012
Journal: Blood
Title: ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53.
Volume: 120
Issue: 14
Pages: 2868-78
Publication
First Author: Wang HW
Year: 2008
Journal: FASEB J
Title: Deficiency of ROCK1 in bone marrow-derived cells protects against atherosclerosis in LDLR-/- mice.
Volume: 22
Issue: 10
Pages: 3561-70
Publication  
First Author: Penumatsa KC
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Vascular smooth muscle ROCK1 contributes to hypoxia-induced pulmonary hypertension development in mice.
Volume: 604
Pages: 137-143
Publication
First Author: Wang W
Year: 2012
Journal: Cell Metab
Title: Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells.
Volume: 15
Issue: 2
Pages: 186-200
Publication
First Author: Fu P
Year: 2006
Journal: J Am Soc Nephrol
Title: Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice.
Volume: 17
Issue: 11
Pages: 3105-14
Publication
First Author: Vemula S
Year: 2010
Journal: Blood
Title: ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability.
Volume: 115
Issue: 9
Pages: 1785-96
Publication
First Author: Liu Y
Year: 2016
Journal: Exp Cell Res
Title: Mouse macrophage polarity and ROCK1 activity depend on RhoA and non-apoptotic Caspase 3.
Volume: 341
Issue: 2
Pages: 225-36
Publication  
First Author: Shi J
Year: 2013
Journal: Cell Death Dis
Title: Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment.
Volume: 4
Pages: e483
Publication
First Author: Knipe RS
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.
Volume: 58
Issue: 4
Pages: 471-481
Publication
First Author: Greathouse KM
Year: 2018
Journal: Brain Struct Funct
Title: Distinct and complementary functions of rho kinase isoforms ROCK1 and ROCK2 in prefrontal cortex structural plasticity.
Volume: 223
Issue: 9
Pages: 4227-4241
Publication
First Author: Kapur R
Year: 2016
Journal: Oncotarget
Title: ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells.
Volume: 7
Issue: 13
Pages: 16936-47
Publication
First Author: Shi J
Year: 2018
Journal: Oncotarget
Title: Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity.
Volume: 9
Issue: 16
Pages: 12995-13008
Publication
First Author: Henderson BW
Year: 2016
Journal: J Neurochem
Title: Rho-associated protein kinase 1 (ROCK1) is increased in Alzheimer's disease and ROCK1 depletion reduces amyloid-β levels in brain.
Volume: 138
Issue: 4
Pages: 525-31
Publication
First Author: Sunamura S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Different roles of myocardial ROCK1 and ROCK2 in cardiac dysfunction and postcapillary pulmonary hypertension in mice.
Volume: 115
Issue: 30
Pages: E7129-E7138
Publication
First Author: Kim JY
Year: 2009
Journal: Dev Biol
Title: Shh and ROCK1 modulate the dynamic epithelial morphogenesis in circumvallate papilla development.
Volume: 325
Issue: 1
Pages: 273-80
Publication
First Author: Shi J
Year: 2019
Journal: FASEB J
Title: Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging.
Volume: 33
Issue: 6
Pages: 7348-7362
Publication
First Author: Bu DX
Year: 2010
Journal: Circ Res
Title: Activation of the ROCK1 branch of the transforming growth factor-beta pathway contributes to RAGE-dependent acceleration of atherosclerosis in diabetic ApoE-null mice.
Volume: 106
Issue: 6
Pages: 1040-51
Publication    
First Author: Julian L
Year: 2021
Journal: Elife
Title: Defective apoptotic cell contractility provokes sterile inflammation, leading to liver damage and tumour suppression.
Volume: 10
Publication
First Author: Dennehey BK
Year: 2004
Journal: Genomics
Title: Inversion, duplication, and changes in gene context are associated with human chromosome 18 evolution.
Volume: 83
Issue: 3
Pages: 493-501
Publication
First Author: Huang H
Year: 2012
Journal: Nat Neurosci
Title: Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling.
Volume: 15
Issue: 10
Pages: 1391-8
Publication
First Author: Dasgupta SK
Year: 2013
Journal: PLoS One
Title: Rho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserine exposure in platelets.
Volume: 8
Issue: 12
Pages: e84649
Publication
First Author: Li M
Year: 2022
Journal: Theranostics
Title: Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation.
Volume: 12
Issue: 5
Pages: 2133-2149
Publication  
First Author: Butler MB
Year: 2019
Journal: J Cell Sci
Title: Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure.
Volume: 132
Issue: 13
Publication
First Author: Rikitake Y
Year: 2005
Journal: Circulation
Title: Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice.
Volume: 112
Issue: 19
Pages: 2959-65
Publication
First Author: Huang H
Year: 2018
Journal: J Clin Invest
Title: Rho-kinase/AMPK axis regulates hepatic lipogenesis during overnutrition.
Volume: 128
Issue: 12
Pages: 5335-5350
Publication
First Author: Wei L
Year: 2020
Journal: FASEB J
Title: ROCK2 inhibition enhances the thermogenic program in white and brown fat tissue in mice.
Volume: 34
Issue: 1
Pages: 474-493
Publication
First Author: Luo J
Year: 2015
Journal: Endocrinology
Title: FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice.
Volume: 156
Issue: 6
Pages: 2200-10
Publication
First Author: Kasahara DI
Year: 2015
Journal: Am J Physiol Lung Cell Mol Physiol
Title: ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice.
Volume: 309
Issue: 7
Pages: L736-46
Publication
First Author: Yao L
Year: 2013
Journal: Cardiovasc Res
Title: Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.
Volume: 97
Issue: 3
Pages: 509-19
Publication
First Author: Zhao Z
Year: 2004
Journal: Dev Biol
Title: Rho-associated kinases play a role in endocardial cell differentiation and migration.
Volume: 275
Issue: 1
Pages: 183-91
Publication
First Author: Mong PY
Year: 2009
Journal: J Immunol
Title: Activation of Rho kinase isoforms in lung endothelial cells during inflammation.
Volume: 182
Issue: 4
Pages: 2385-94
Publication
First Author: Vega FM
Year: 2011
Journal: J Cell Biol
Title: RhoA and RhoC have distinct roles in migration and invasion by acting through different targets.
Volume: 193
Issue: 4
Pages: 655-65
Publication
First Author: Leong SY
Year: 2011
Journal: Stem Cells
Title: The Rho kinase pathway regulates mouse adult neural precursor cell migration.
Volume: 29
Issue: 2
Pages: 332-43
Publication
First Author: Laeno AM
Year: 2013
Journal: Biol Reprod
Title: Rho-associated kinase activity is required for proper morphogenesis of the inner cell mass in the mouse blastocyst.
Volume: 89
Issue: 5
Pages: 122
Publication
First Author: Daley WP
Year: 2012
Journal: Development
Title: ROCK1-directed basement membrane positioning coordinates epithelial tissue polarity.
Volume: 139
Issue: 2
Pages: 411-22
Publication  
First Author: Kümper S
Year: 2016
Journal: Elife
Title: Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis.
Volume: 5
Pages: e12994
Publication
First Author: Peng H
Year: 2016
Journal: J Am Soc Nephrol
Title: CKD Stimulates Muscle Protein Loss Via Rho-associated Protein Kinase 1 Activation.
Volume: 27
Issue: 2
Pages: 509-19
Publication
First Author: Yang X
Year: 2012
Journal: FASEB J
Title: Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1.
Volume: 26
Issue: 5
Pages: 2105-16
Publication
First Author: Okamoto R
Year: 2013
Journal: FASEB J
Title: FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.
Volume: 27
Issue: 4
Pages: 1439-49
Publication
First Author: Whitlock NA
Year: 2009
Journal: J Ocul Pharmacol Ther
Title: Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK.
Volume: 25
Issue: 3
Pages: 187-94
Publication
First Author: Gallo RM
Year: 2012
Journal: J Immunol
Title: Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d.
Volume: 189
Issue: 4
Pages: 1689-98
Publication
First Author: Escuin S
Year: 2015
Journal: J Cell Sci
Title: Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure.
Volume: 128
Issue: 14
Pages: 2468-81
Publication
First Author: Phillips HM
Year: 2005
Journal: Circ Res
Title: Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract.
Volume: 96
Issue: 3
Pages: 292-9
Publication
First Author: Ferrón SR
Year: 2009
Journal: J Neurosci
Title: Telomere shortening in neural stem cells disrupts neuronal differentiation and neuritogenesis.
Volume: 29
Issue: 46
Pages: 14394-407
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Rikitake Y
Year: 2005
Journal: Circulation
Title: Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells.
Volume: 111
Issue: 24
Pages: 3261-8
Publication
First Author: Haudek SB
Year: 2009
Journal: Cardiovasc Res
Title: Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation.
Volume: 83
Issue: 3
Pages: 511-8
Publication
First Author: Mehrotra S
Year: 2012
Journal: J Immunol
Title: A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice.
Volume: 189
Issue: 4
Pages: 1627-38
Publication
First Author: Ohta Y
Year: 2006
Journal: Nat Cell Biol
Title: FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling.
Volume: 8
Issue: 8
Pages: 803-14
Publication
First Author: Ichida M
Year: 2011
Journal: FEBS Lett
Title: Changes in cell migration of mesenchymal cells during osteogenic differentiation.
Volume: 585
Issue: 24
Pages: 4018-24
Publication
First Author: Suprynowicz FA
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells.
Volume: 109
Issue: 49
Pages: 20035-40
Publication
First Author: Guolla L
Year: 2012
Journal: J Cell Sci
Title: Force transduction and strain dynamics in actin stress fibres in response to nanonewton forces.
Volume: 125
Issue: Pt 3
Pages: 603-13
GXD Expression    
Probe: MGI:3775420
Assay Type: Western blot
Annotation Date: 2008-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691621
Stage: TS21
Assay Id: MGI:3775459
Age: embryonic day 13.0
Image: 6
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6740383
Assay Type: Northern blot
Annotation Date: 2021-08-18
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6740390
Age: postnatal week 14
Specimen Label: Spleen
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6740383
Assay Type: Northern blot
Annotation Date: 2021-08-18
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:6740390
Age: postnatal week 14
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6740383
Assay Type: Northern blot
Annotation Date: 2021-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:6740390
Age: embryonic day 17.0
Specimen Label: Placenta
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5694260
Assay Type: RT-PCR
Annotation Date: 2015-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1817828
Stage: TS28
Assay Id: MGI:5694263
Age: postnatal adult
Specimen Label: latissimus d.
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:3775420
Assay Type: Western blot
Annotation Date: 2012-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3667218
Stage: TS18
Assay Id: MGI:5318701
Age: embryonic day 11.0
Image: 6
Specimen Label: E11
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3775420
Assay Type: Western blot
Annotation Date: 2012-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3667220
Stage: TS20
Assay Id: MGI:5318701
Age: embryonic day 12.0
Image: 6
Specimen Label: E12
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5694260
Assay Type: RT-PCR
Annotation Date: 2015-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770128
Stage: TS28
Assay Id: MGI:5694263
Age: postnatal adult
Specimen Label: diaphragm
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5694255
Assay Type: Northern blot
Annotation Date: 2015-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1770128
Stage: TS28
Assay Id: MGI:5694265
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5694260
Assay Type: RT-PCR
Annotation Date: 2015-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5694263
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6740383
Assay Type: Northern blot
Annotation Date: 2021-08-18
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6740390
Age: postnatal week 14
Specimen Label: Lung
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6740383
Assay Type: Northern blot
Annotation Date: 2021-08-18
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:6740390
Age: postnatal week 14
Specimen Label: Muscle
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5694260
Assay Type: RT-PCR
Annotation Date: 2015-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5694263
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5694255
Assay Type: Northern blot
Annotation Date: 2015-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5694265
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6740383
Assay Type: Northern blot
Annotation Date: 2021-08-18
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6740390
Age: postnatal week 14
Specimen Label: Heart
Detected: true
Specimen Num: 2