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Search results 1 to 100 out of 123 for Senp3

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0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: Sentrin-specific protease 3 (SENP3, MEROPS identifier C48.003) is an isopeptidase that releases SUMO2 and SUMO3 monomers from sumoylated substrates by hydrolysing the isopeptide bond []. SENP3 is a cysteine peptidase with a fold similar to that of adenain, and has the catalytic triad His, Asp, Cys, the reverse of the order in papain. Among the proteins that are deconjugated by SENP3 are MEF2D [], CDCA8 [], EP300 [], and nucleophosmin []. SENP3 is a component of the 5FMC []and MLL1/MLL complexes [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Huang C
Year: 2009
Journal: EMBO J
Title: SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation.
Volume: 28
Issue: 18
Pages: 2748-62
Publication
First Author: Klein UR
Year: 2009
Journal: Mol Biol Cell
Title: RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin.
Volume: 20
Issue: 1
Pages: 410-8
Publication  
First Author: Cai Z
Year: 2021
Journal: EBioMedicine
Title: Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of ╬▓-catenin and regulation of its stability.
Volume: 67
Pages: 103386
Publication
First Author: Zhang Y
Year: 2020
Journal: Cell Rep
Title: SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes.
Volume: 30
Issue: 6
Pages: 1951-1963.e4
Publication
First Author: Haindl M
Year: 2008
Journal: EMBO Rep
Title: The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing.
Volume: 9
Issue: 3
Pages: 273-9
Publication
First Author: Hu Z
Year: 2021
Journal: Mol Cell
Title: SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function.
Volume: 81
Issue: 5
Pages: 940-952.e5
Protein
Organism: Mus musculus
Length: 568  
Fragment?: false
Publication
First Author: Lao Y
Year: 2018
Journal: J Biol Chem
Title: DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
Volume: 293
Issue: 11
Pages: 3965-3980
Publication
First Author: Gr├ęgoire S
Year: 2005
Journal: Mol Cell Biol
Title: Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.
Volume: 25
Issue: 6
Pages: 2273-87
Publication
First Author: Gong L
Year: 2006
Journal: J Biol Chem
Title: Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3.
Volume: 281
Issue: 23
Pages: 15869-77
Publication
First Author: Fanis P
Year: 2012
Journal: Mol Cell Proteomics
Title: Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.
Volume: 11
Issue: 11
Pages: 1263-73
Protein
Organism: Mus musculus
Length: 169  
Fragment?: true
Publication
First Author: Dou Y
Year: 2005
Journal: Cell
Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.
Volume: 121
Issue: 6
Pages: 873-85
Publication
First Author: Akiyama H
Year: 2018
Journal: J Comp Neurol
Title: Synaptic localization of the SUMOylation-regulating protease SENP5 in the adult mouse brain.
Volume: 526
Issue: 6
Pages: 990-1005
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Nishida T
Year: 2000
Journal: Eur J Biochem
Title: A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase.
Volume: 267
Issue: 21
Pages: 6423-7
GXD Expression    
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:6682092
Age: postnatal day 1
Image: 3
Specimen Label: P1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:6682092
Age: postnatal day 2
Image: 3
Specimen Label: P2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:6682092
Age: postnatal day 3
Image: 3
Specimen Label: P3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6682092
Age: postnatal day 4
Image: 3
Specimen Label: P4
Specimen Num: 4
GXD Expression    
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6682092
Age: postnatal day 5
Image: 3
Specimen Label: P5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6682092
Age: postnatal day 6
Image: 3
Specimen Label: P6
Specimen Num: 6
GXD Expression      
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6682092
Age: postnatal day 7
Image: 3
Specimen Label: P7
Specimen Num: 7
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6682084
Age: embryonic day 10.5
Image: 2A E10.5
Specimen Label: 2A E10.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6682084
Age: embryonic day 13.5
Image: 2A E13.5
Specimen Label: 2A E13.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6682084
Age: embryonic day 15.5
Image: 2A E15.5
Specimen Label: 2A E15.5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6682084
Age: embryonic day 17.5
Image: 2A E17.5
Specimen Label: 2A E17.5
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6682084
Age: embryonic day 19.5
Image: 2A E19.5
Specimen Label: 2A E19.5
Detected: true
Specimen Num: 5
Publication
First Author: Guo C
Year: 2013
Journal: EMBO J
Title: SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia.
Volume: 32
Issue: 11
Pages: 1514-28
Publication
First Author: Liu K
Year: 2020
Journal: Autophagy
Title: A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.
Volume: 16
Issue: 6
Pages: 975-990
Publication
First Author: Yeh ET
Year: 2000
Journal: Gene
Title: Ubiquitin-like proteins: new wines in new bottles.
Volume: 248
Issue: 1-2
Pages: 1-14
Publication
First Author: Yamada S
Year: 2021
Journal: iScience
Title: Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development.
Volume: 24
Issue: 12
Pages: 103484
Publication
First Author: Yang CY
Year: 2019
Journal: J Neurosci
Title: Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation.
Volume: 39
Issue: 25
Pages: 4959-4975
Publication
First Author: Zhang X
Year: 2020
Journal: PLoS One
Title: Zinc deficiency induces abnormal development of the myocardium by promoting SENP5 overexpression.
Volume: 15
Issue: 11
Pages: e0242606
Publication      
First Author: Centre for Modeling Human Disease
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: GemPharmatech
Year: 2020
Journal: website
Title: GemPharmatech website
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Shao L
Year: 2020
Journal: FASEB J
Title: SUMO1 SUMOylates and SENP3 deSUMOylates NLRP3 to orchestrate the inflammasome activation.
Volume: 34
Issue: 1
Pages: 1497-1515
Publication
First Author: Nayak A
Year: 2019
Journal: Cell Rep
Title: Regulation of SETD7 Methyltransferase by SENP3 Is Crucial for Sarcomere Organization and Cachexia.
Volume: 27
Issue: 9
Pages: 2725-2736.e4
Publication
First Author: Yun C
Year: 2008
Journal: J Cell Biol
Title: Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases.
Volume: 183
Issue: 4
Pages: 589-95
Allele
Name: tumor necrosis factor (ligand) superfamily, member 13; targeted mutation 1, Avi Ashkenazi
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: tumor necrosis factor (ligand) superfamily, member 13; targeted mutation 1, Raif S Geha
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication
First Author: Varfolomeev E
Year: 2004
Journal: Mol Cell Biol
Title: APRIL-deficient mice have normal immune system development.
Volume: 24
Issue: 3
Pages: 997-1006
Publication
First Author: Hardenberg G
Year: 2008
Journal: Mol Immunol
Title: APRIL affects antibody responses and early leukocyte infiltration, but not influenza A viral control.
Volume: 45
Issue: 11
Pages: 3050-8
Publication
First Author: Huard B
Year: 2008
Journal: J Clin Invest
Title: APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa.
Volume: 118
Issue: 8
Pages: 2887-95
Publication
First Author: Matthes T
Year: 2015
Journal: Leukemia
Title: Myelopoiesis dysregulation associated to sustained APRIL production in multiple myeloma-infiltrated bone marrow.
Volume: 29
Issue: 9
Pages: 1901-8
Publication
First Author: Matthes T
Year: 2011
Journal: Blood
Title: Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow.
Volume: 118
Issue: 7
Pages: 1838-44
Publication
First Author: Huard B
Year: 2012
Journal: PLoS One
Title: Selective APRIL blockade delays systemic lupus erythematosus in mouse.
Volume: 7
Issue: 2
Pages: e31837
Publication
First Author: Castigli E
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Impaired IgA class switching in APRIL-deficient mice.
Volume: 101
Issue: 11
Pages: 3903-8