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Search results 1 to 100 out of 144 for Senp3

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: Sentrin-specific protease 3 (SENP3, MEROPS identifier C48.003) is an isopeptidase that releases SUMO2 and SUMO3 monomers from sumoylated substrates by hydrolysing the isopeptide bond []. SENP3 is a cysteine peptidase with a fold similar to that of adenain, and has the catalytic triad His, Asp, Cys, the reverse of the order in papain. Among the proteins that are deconjugated by SENP3 are MEF2D [], CDCA8 [], EP300 [], and nucleophosmin []. SENP3 is a component of the 5FMC []and MLL1/MLL complexes [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Huang C
Year: 2009
Journal: EMBO J
Title: SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation.
Volume: 28
Issue: 18
Pages: 2748-62
Publication
First Author: Xiao M
Year: 2022
Journal: Mol Oncol
Title: SENP3 loss promotes M2 macrophage polarization and breast cancer progression.
Volume: 16
Issue: 4
Pages: 1026-1044
Publication
First Author: Klein UR
Year: 2009
Journal: Mol Biol Cell
Title: RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin.
Volume: 20
Issue: 1
Pages: 410-8
Protein
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
Publication
First Author: Haindl M
Year: 2008
Journal: EMBO Rep
Title: The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing.
Volume: 9
Issue: 3
Pages: 273-9
Publication
First Author: Chen X
Year: 2020
Journal: J Cell Mol Med
Title: SENP3 in monocytes/macrophages up-regulates tissue factor and mediates lipopolysaccharide-induced acute lung injury by enhancing JNK phosphorylation.
Volume: 24
Issue: 10
Pages: 5454-5462
Publication
First Author: He S
Year: 2023
Journal: Innate Immun
Title: SENP3 facilitates M1 macrophage polarization via the HIF-1α/PKM2 axis in lipopolysaccharide-induced acute lung injury.
Volume: 29
Issue: 1-2
Pages: 25-34
Publication  
First Author: Cai Z
Year: 2021
Journal: EBioMedicine
Title: Redox-sensitive enzyme SENP3 mediates vascular remodeling via de-SUMOylation of β-catenin and regulation of its stability.
Volume: 67
Pages: 103386
Publication
First Author: Zhang Y
Year: 2020
Journal: Cell Rep
Title: SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes.
Volume: 30
Issue: 6
Pages: 1951-1963.e4
Publication
First Author: Bao X
Year: 2023
Journal: Immun Inflamm Dis
Title: Loss of SENP3 mediated the formation of nasal polyps in nasal mucosal inflammation by increasing alternative activated macrophage.
Volume: 11
Issue: 2
Pages: e781
Publication
First Author: Hu Z
Year: 2021
Journal: Mol Cell
Title: SENP3 senses oxidative stress to facilitate STING-dependent dendritic cell antitumor function.
Volume: 81
Issue: 5
Pages: 940-952.e5
Publication
First Author: Lao Y
Year: 2018
Journal: J Biol Chem
Title: DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
Volume: 293
Issue: 11
Pages: 3965-3980
Publication
First Author: Jiang Y
Year: 2023
Journal: Cell Mol Life Sci
Title: Myeloid SENP3 deficiency protects mice from diet and age-induced obesity via regulation of YAP1 SUMOylation.
Volume: 81
Issue: 1
Pages: 4
Publication
First Author: Yu X
Year: 2018
Journal: Nat Commun
Title: SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.
Volume: 9
Issue: 1
Pages: 3157
Publication
First Author: Grégoire S
Year: 2005
Journal: Mol Cell Biol
Title: Association with class IIa histone deacetylases upregulates the sumoylation of MEF2 transcription factors.
Volume: 25
Issue: 6
Pages: 2273-87
Publication
First Author: Gong L
Year: 2006
Journal: J Biol Chem
Title: Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3.
Volume: 281
Issue: 23
Pages: 15869-77
Publication
First Author: Fanis P
Year: 2012
Journal: Mol Cell Proteomics
Title: Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.
Volume: 11
Issue: 11
Pages: 1263-73
Protein
Organism: Mus musculus/domesticus
Length: 169  
Fragment?: true
Publication
First Author: Dou Y
Year: 2005
Journal: Cell
Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.
Volume: 121
Issue: 6
Pages: 873-85
Publication
First Author: Akiyama H
Year: 2018
Journal: J Comp Neurol
Title: Synaptic localization of the SUMOylation-regulating protease SENP5 in the adult mouse brain.
Volume: 526
Issue: 6
Pages: 990-1005
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Nishida T
Year: 2000
Journal: Eur J Biochem
Title: A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase.
Volume: 267
Issue: 21
Pages: 6423-7
GXD Expression    
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:6682092
Age: postnatal day 1
Image: 3
Specimen Label: P1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:6682092
Age: postnatal day 2
Image: 3
Specimen Label: P2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:6682092
Age: postnatal day 3
Image: 3
Specimen Label: P3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6682092
Age: postnatal day 4
Image: 3
Specimen Label: P4
Specimen Num: 4
GXD Expression    
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6682092
Age: postnatal day 5
Image: 3
Specimen Label: P5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6682092
Age: postnatal day 6
Image: 3
Specimen Label: P6
Specimen Num: 6
GXD Expression      
Probe: MGI:6681916
Assay Type: Western blot
Annotation Date: 2021-04-09
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6682092
Age: postnatal day 7
Image: 3
Specimen Label: P7
Specimen Num: 7
GXD Expression  
Probe: MGI:7580476
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7580512
Age: embryonic day 16.5
Image: S4B
Specimen Label: S4B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7580476
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7580512
Age: embryonic day 13.5
Image: S4A
Specimen Label: S4A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7580476
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7580512
Age: embryonic day 16.5
Image: S4B
Specimen Label: S4B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:7580476
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7580512
Age: embryonic day 16.5
Image: S4B
Specimen Label: S4B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6682084
Age: embryonic day 10.5
Image: 2A E10.5
Specimen Label: 2A E10.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6682084
Age: embryonic day 13.5
Image: 2A E13.5
Specimen Label: 2A E13.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6682084
Age: embryonic day 15.5
Image: 2A E15.5
Specimen Label: 2A E15.5
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6682084
Age: embryonic day 17.5
Image: 2A E17.5
Specimen Label: 2A E17.5
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6681916
Assay Type: Immunohistochemistry
Annotation Date: 2021-04-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6682084
Age: embryonic day 19.5
Image: 2A E19.5
Specimen Label: 2A E19.5
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:7580476
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7580512
Age: embryonic day 13.5
Image: S4A
Specimen Label: S4A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7580476
Assay Type: Immunohistochemistry
Annotation Date: 2024-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7580512
Age: embryonic day 16.5
Image: S4B
Specimen Label: S4B
Detected: true
Specimen Num: 2
Publication
First Author: Guo C
Year: 2013
Journal: EMBO J
Title: SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia.
Volume: 32
Issue: 11
Pages: 1514-28
Publication
First Author: Liu K
Year: 2020
Journal: Autophagy
Title: A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.
Volume: 16
Issue: 6
Pages: 975-990
Publication
First Author: Yeh ET
Year: 2000
Journal: Gene
Title: Ubiquitin-like proteins: new wines in new bottles.
Volume: 248
Issue: 1-2
Pages: 1-14
Publication
First Author: Yamada S
Year: 2021
Journal: iScience
Title: Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development.
Volume: 24
Issue: 12
Pages: 103484
Publication
First Author: Yang CY
Year: 2019
Journal: J Neurosci
Title: Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation.
Volume: 39
Issue: 25
Pages: 4959-4975
Publication
First Author: Zhang X
Year: 2020
Journal: PLoS One
Title: Zinc deficiency induces abnormal development of the myocardium by promoting SENP5 overexpression.
Volume: 15
Issue: 11
Pages: e0242606
Publication      
First Author: Centre for Modeling Human Disease
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto
Publication      
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load