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Search results 1 to 87 out of 87 for Shank1

0.028s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication  
First Author: Silverman JL
Year: 2011
Journal: Brain Res
Title: Sociability and motor functions in Shank1 mutant mice.
Volume: 1380
Pages: 120-37
Publication
First Author: Mao W
Year: 2015
Journal: Eur J Neurosci
Title: Shank1 regulates excitatory synaptic transmission in mouse hippocampal parvalbumin-expressing inhibitory interneurons.
Volume: 41
Issue: 8
Pages: 1025-35
Publication  
First Author: Sungur AÖ
Year: 2014
Journal: J Neurosci Methods
Title: Repetitive behaviors in the Shank1 knockout mouse model for autism spectrum disorder: developmental aspects and effects of social context.
Volume: 234
Pages: 92-100
Protein
Organism: Mus musculus
Length: 2167  
Fragment?: false
Publication
First Author: Wöhr M
Year: 2011
Journal: PLoS One
Title: Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior.
Volume: 6
Issue: 6
Pages: e20631
Publication
First Author: Hung AY
Year: 2008
Journal: J Neurosci
Title: Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.
Volume: 28
Issue: 7
Pages: 1697-708
Publication  
First Author: Sungur AÖ
Year: 2018
Journal: Front Mol Neurosci
Title: Reduced Efficacy of d-Amphetamine and 3,4-Methylenedioxymethamphetamine in Inducing Hyperactivity in Mice Lacking the Postsynaptic Scaffolding Protein SHANK1.
Volume: 11
Pages: 419
Publication
First Author: Uemura T
Year: 2004
Journal: Mol Cell Neurosci
Title: Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.
Volume: 26
Issue: 2
Pages: 330-41
Publication
First Author: Schütt J
Year: 2009
Journal: J Biol Chem
Title: Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.
Volume: 284
Issue: 38
Pages: 25479-87
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Stella SL Jr
Year: 2012
Journal: PLoS One
Title: Association of shank 1A scaffolding protein with cone photoreceptor terminals in the mammalian retina.
Volume: 7
Issue: 9
Pages: e43463
GXD Expression      
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:3641157
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3641157
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641157
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641157
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641157
Age: postnatal week 8
Specimen Label: 8W
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3641151
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3641161
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3641151
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3641161
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3641151
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3641161
Age: postnatal week 8
Specimen Label: 8W
Detected: true
Specimen Num: 3
Publication
First Author: Francke F
Year: 2005
Journal: Brain Res Mol Brain Res
Title: Immunohistochemical distribution of MIZIP and its co-expression with the Melanin-concentrating hormone receptor 1 in the adult rodent brain.
Volume: 139
Issue: 1
Pages: 31-41
Publication  
First Author: Filice F
Year: 2016
Journal: Mol Brain
Title: Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism.
Volume: 9
Pages: 10
Publication
First Author: Jiang YH
Year: 2013
Journal: Neuron
Title: Modeling autism by SHANK gene mutations in mice.
Volume: 78
Issue: 1
Pages: 8-27
Publication
First Author: Yoshida T
Year: 2011
Journal: J Neurosci
Title: IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase δ.
Volume: 31
Issue: 38
Pages: 13485-99
Publication
First Author: Sakai Y
Year: 2011
Journal: Sci Transl Med
Title: Protein interactome reveals converging molecular pathways among autism disorders.
Volume: 3
Issue: 86
Pages: 86ra49
Publication
First Author: Uchino S
Year: 2006
Journal: J Neurochem
Title: Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.
Volume: 97
Issue: 4
Pages: 1203-14
Publication
First Author: Zhang J
Year: 2017
Journal: Cell Rep
Title: A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry.
Volume: 21
Issue: 3
Pages: 666-678
Publication
First Author: Mendus D
Year: 2014
Journal: Eur J Neurosci
Title: Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.
Volume: 39
Issue: 8
Pages: 1256-67
Publication  
First Author: Berkel S
Year: 2018
Journal: Front Mol Neurosci
Title: Sex Hormones Regulate SHANK Expression.
Volume: 11
Pages: 337
Publication
First Author: Dani A
Year: 2010
Journal: Neuron
Title: Superresolution imaging of chemical synapses in the brain.
Volume: 68
Issue: 5
Pages: 843-56
Publication  
First Author: Huang LC
Year: 2012
Journal: Neural Dev
Title: Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.
Volume: 7
Pages: 38
Publication
First Author: Kazdoba TM
Year: 2016
Journal: Genes Brain Behav
Title: Behavioral phenotypes of genetic mouse models of autism.
Volume: 15
Issue: 1
Pages: 7-26
Publication  
First Author: Wang Z
Year: 2020
Journal: eNeuro
Title: The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development.
Volume: 7
Issue: 4
Publication
First Author: Quesnel-Vallières M
Year: 2016
Journal: Mol Cell
Title: Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.
Volume: 64
Issue: 6
Pages: 1023-1034
Publication
First Author: Verpelli C
Year: 2011
Journal: J Biol Chem
Title: Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.
Volume: 286
Issue: 40
Pages: 34839-50
Publication
First Author: Quesnel-Vallières M
Year: 2015
Journal: Genes Dev
Title: Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.
Volume: 29
Issue: 7
Pages: 746-59
Publication
First Author: Sawallisch C
Year: 2009
Journal: J Biol Chem
Title: The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.
Volume: 284
Issue: 14
Pages: 9225-36
Publication
First Author: Farini D
Year: 2020
Journal: Cell Rep
Title: A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.
Volume: 31
Issue: 9
Pages: 107703
Publication
First Author: Thuret S
Year: 2004
Journal: Mol Cell Neurosci
Title: Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.
Volume: 25
Issue: 3
Pages: 394-405
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: GemPharmatech
Year: 2020
Journal: website
Title: GemPharmatech website
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Zhang Y
Year: 2014
Journal: RNA Biol
Title: FMRP interacts with G-quadruplex structures in the 3'-UTR of its dendritic target Shank1 mRNA.
Volume: 11
Issue: 11
Pages: 1364-74
Publication
First Author: Boeckers TM
Year: 2002
Journal: J Neurochem
Title: ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease.
Volume: 81
Issue: 5
Pages: 903-10
Publication
First Author: Ehlers MD
Year: 1999
Journal: Curr Biol
Title: Synapse structure: glutamate receptors connected by the shanks.
Volume: 9
Issue: 22
Pages: R848-50
Publication  
First Author: Sheng M
Year: 2000
Journal: J Cell Sci
Title: The Shank family of scaffold proteins.
Volume: 113 ( Pt 11)
Pages: 1851-6
Protein Domain
Type: Domain
Description: Shank1, also called SSTRIP (Somatostatin receptor-interacting protein), is a brain-specific protein that plays a role in the construction of postsynaptic density (PSD) and the maturation of dendritic spines [, ]. Mice deficient in Shank1 show altered PSD composition, thinner PSDs, smaller dendritic spines, and weaker basal synaptic transmission, although synaptic plasticity is normal. They show increased anxiety and impaired fear memory, but also show better spatial learning [, , ]. A Shank protein carries scaffolding functions through multiple sites of protein-protein interaction in its domain architecture, including ankyrin (ANK) repeats, a long proline rich region, as well as SH3, PDZ, and SAM domains.This entry represents the SH3 domain of Shank1 which binds GRIP, a scaffold protein that binds AMPA receptors and Eph receptors/ligands [].
Publication
First Author: Lilja J
Year: 2017
Journal: Nat Cell Biol
Title: SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.
Volume: 19
Issue: 4
Pages: 292-305
Publication
First Author: Pham E
Year: 2010
Journal: FEBS J
Title: Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins.
Volume: 277
Issue: 14
Pages: 3051-67
Publication  
First Author: Lin CW
Year: 2014
Journal: Front Cell Neurosci
Title: Sarm1 deficiency impairs synaptic function and leads to behavioral deficits, which can be ameliorated by an mGluR allosteric modulator.
Volume: 8
Pages: 87