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Search results 1 to 100 out of 119 for Shank1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
50944 | SHANK1
Type: gene
Organism: human
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Gene
100486091 | shank1
Type: gene
Organism: frog, western clawed
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Gene
78957 | Shank1
Type: gene
Organism: rat
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Gene
484359 | SHANK1
Type: gene
Organism: dog, domestic
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Gene
468967 | SHANK1
Type: gene
Organism: chimpanzee
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Gene
518970 | SHANK1
Type: gene
Organism: cattle
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Gene
568908 | shank1
Type: gene
Organism: zebrafish
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Gene
719673 | SHANK1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:3613677 | Shank1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
20868654 | J:170750
 
First Author: Silverman JL
Year: 2011
Journal: Brain Res
Title: Sociability and motor functions in Shank1 mutant mice.
Volume: 1380
Pages: 120-37
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Publication
33402706 | J:331776
First Author: Mossa A
Year: 2021
Journal: Mol Psychiatry
Title: Developmental impaired Akt signaling in the Shank1 and Shank3 double knock-out mice.
Volume: 26
Issue: 6
Pages: 1928-1944
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Publication
25816842 | J:253380
First Author: Mao W
Year: 2015
Journal: Eur J Neurosci
Title: Shank1 regulates excitatory synaptic transmission in mouse hippocampal parvalbumin-expressing inhibitory interneurons.
Volume: 41
Issue: 8
Pages: 1025-35
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Publication
37880287 | J:357936
First Author: Qin Y
Year: 2023
Journal: Transl Psychiatry
Title: Downregulation of mGluR1-mediated signaling underlying autistic-like core symptoms in Shank1 P1812L-knock-in mice.
Volume: 13
Issue: 1
Pages: 329
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Publication
35181969 | J:350710
First Author: Chen QN
Year: 2022
Journal: Eur J Neurosci
Title: Suv39h1 regulates memory stability by inhibiting the expression of Shank1 in hippocampal newborn neurons.
Volume: 55
Issue: 6
Pages: 1424-1441
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Publication
24820912 | J:317636
 
First Author: Sungur AÖ
Year: 2014
Journal: J Neurosci Methods
Title: Repetitive behaviors in the Shank1 knockout mouse model for autism spectrum disorder: developmental aspects and effects of social context.
Volume: 234
Pages: 92-100
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Protein
D3YZU1
Organism: Mus musculus/domesticus
Length: 2167  
Fragment?: false
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Publication
21695253 | J:174446
First Author: Wöhr M
Year: 2011
Journal: PLoS One
Title: Communication impairments in mice lacking Shank1: reduced levels of ultrasonic vocalizations and scent marking behavior.
Volume: 6
Issue: 6
Pages: e20631
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Publication
18272690 | J:132277
First Author: Hung AY
Year: 2008
Journal: J Neurosci
Title: Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.
Volume: 28
Issue: 7
Pages: 1697-708
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Publication
30505269 | J:288905
 
First Author: Sungur AÖ
Year: 2018
Journal: Front Mol Neurosci
Title: Reduced Efficacy of d-Amphetamine and 3,4-Methylenedioxymethamphetamine in Inducing Hyperactivity in Mice Lacking the Postsynaptic Scaffolding Protein SHANK1.
Volume: 11
Pages: 419
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Publication
15207857 | J:150922
First Author: Uemura T
Year: 2004
Journal: Mol Cell Neurosci
Title: Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.
Volume: 26
Issue: 2
Pages: 330-41
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Publication
19640847 | J:156357
First Author: Schütt J
Year: 2009
Journal: J Biol Chem
Title: Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities.
Volume: 284
Issue: 38
Pages: 25479-87
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Protein Coding Gene
MGP_CAROLIEiJ_G0029655 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032158 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032137 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032073 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031865 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3613677 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032641 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031193 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031829 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031987 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032065 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031975 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032657 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012880 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030753 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
22984429 | J:191880
First Author: Stella SL Jr
Year: 2012
Journal: PLoS One
Title: Association of shank 1A scaffolding protein with cone photoreceptor terminals in the mammalian retina.
Volume: 7
Issue: 9
Pages: e43463
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GXD Expression
GXD Expression
     
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:3641157
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3641157
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641157
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641157
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3641148
Assay Type: RT-PCR
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3641157
Age: postnatal week 8
Specimen Label: 8W
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7428987
Assay Type: RT-PCR
Annotation Date: 2023-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7429012
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7428987
Assay Type: RT-PCR
Annotation Date: 2023-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7429012
Age: embryonic day 18.5
Specimen Label: +/delta7-8
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7428987
Assay Type: RT-PCR
Annotation Date: 2023-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7429012
Age: embryonic day 18.5
Specimen Label: delta7-8/delta7-8
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7439184
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7439226
Age: postnatal day 7.5
Image: 3
Specimen Label: P7.5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7439184
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7439226
Age: postnatal day 7.5
Image: 3
Specimen Label: P7.5 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7439184
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Stage: TS25
Assay Id: MGI:7439244
Age: embryonic day 17.5
Image: S2
Specimen Label: E17.5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7439184
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754425
Stage: TS25
Assay Id: MGI:7439244
Age: embryonic day 17.5
Image: S2
Specimen Label: E17.5 cKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7439184
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:3558925
Stage: TS25
Assay Id: MGI:7439251
Age: embryonic day 17.5
Image: S2
Specimen Label: E17.5 male
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7439184
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:3558925
Stage: TS25
Assay Id: MGI:7439251
Age: embryonic day 17.5
Image: S2
Specimen Label: E17.5 female
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7439184
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:7439251
Age: postnatal day 7.5
Image: S2
Specimen Label: P7.5 male
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7439184
Assay Type: RT-PCR
Annotation Date: 2023-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:7439251
Age: postnatal day 7.5
Image: S2
Specimen Label: P7.5 female
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7439212
Assay Type: Western blot
Annotation Date: 2023-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:3558925
Stage: TS25
Assay Id: MGI:7439256
Age: embryonic day 17.5
Image: 4
Specimen Label: E17.5 male
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7439212
Assay Type: Western blot
Annotation Date: 2023-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:3558925
Stage: TS25
Assay Id: MGI:7439256
Age: embryonic day 17.5
Image: 4
Specimen Label: E17.5 female
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7439212
Assay Type: Western blot
Annotation Date: 2023-02-28
Strength: Present
Sex: Female
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:7439259
Age: postnatal day 7.5
Image: 4
Specimen Label: P7.5 female
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7439212
Assay Type: Western blot
Annotation Date: 2023-02-28
Strength: Present
Sex: Male
Emaps: EMAPS:3535728
Stage: TS28
Assay Id: MGI:7439259
Age: postnatal day 7.5
Image: 4
Specimen Label: P7.5 male
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3641151
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3641161
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3641151
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3641161
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3641151
Assay Type: RNA in situ
Annotation Date: 2006-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3641161
Age: postnatal week 8
Specimen Label: 8W
Detected: true
Specimen Num: 3
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Publication
15950311 | J:101566
First Author: Francke F
Year: 2005
Journal: Brain Res Mol Brain Res
Title: Immunohistochemical distribution of MIZIP and its co-expression with the Melanin-concentrating hormone receptor 1 in the adult rodent brain.
Volume: 139
Issue: 1
Pages: 31-41
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Publication
26819149 | J:259439
 
First Author: Filice F
Year: 2016
Journal: Mol Brain
Title: Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism.
Volume: 9
Pages: 10
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Publication
23583105 | J:197901
First Author: Jiang YH
Year: 2013
Journal: Neuron
Title: Modeling autism by SHANK gene mutations in mice.
Volume: 78
Issue: 1
Pages: 8-27
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Publication
21940441 | J:177124
First Author: Yoshida T
Year: 2011
Journal: J Neurosci
Title: IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase δ.
Volume: 31
Issue: 38
Pages: 13485-99
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Publication
21653829 | J:173460
First Author: Sakai Y
Year: 2011
Journal: Sci Transl Med
Title: Protein interactome reveals converging molecular pathways among autism disorders.
Volume: 3
Issue: 86
Pages: 86ra49
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Publication
16606358 | J:108736
First Author: Uchino S
Year: 2006
Journal: J Neurochem
Title: Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.
Volume: 97
Issue: 4
Pages: 1203-14
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Publication
24460873 | J:227951
First Author: Mendus D
Year: 2014
Journal: Eur J Neurosci
Title: Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.
Volume: 39
Issue: 8
Pages: 1256-67
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Publication
30319350 | J:266512
 
First Author: Berkel S
Year: 2018
Journal: Front Mol Neurosci
Title: Sex Hormones Regulate SHANK Expression.
Volume: 11
Pages: 337
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Publication
29045835 | J:255264
First Author: Zhang J
Year: 2017
Journal: Cell Rep
Title: A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry.
Volume: 21
Issue: 3
Pages: 666-678
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Publication
21144999 | J:237681
First Author: Dani A
Year: 2010
Journal: Neuron
Title: Superresolution imaging of chemical synapses in the brain.
Volume: 68
Issue: 5
Pages: 843-56
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Publication
23217150 | J:191194
 
First Author: Huang LC
Year: 2012
Journal: Neural Dev
Title: Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.
Volume: 7
Pages: 38
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Publication
33374598 | J:348434
 
First Author: Eltokhi A
Year: 2020
Journal: Int J Mol Sci
Title: Glutamatergic Dysfunction and Synaptic Ultrastructural Alterations in Schizophrenia and Autism Spectrum Disorder: Evidence from Human and Rodent Studies.
Volume: 22
Issue: 1
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Publication
32675174 | J:302429
 
First Author: Wang Z
Year: 2020
Journal: eNeuro
Title: The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development.
Volume: 7
Issue: 4
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Publication
26403076 | J:242957
First Author: Kazdoba TM
Year: 2016
Journal: Genes Brain Behav
Title: Behavioral phenotypes of genetic mouse models of autism.
Volume: 15
Issue: 1
Pages: 7-26
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Publication
27984743 | J:249252
First Author: Quesnel-Vallières M
Year: 2016
Journal: Mol Cell
Title: Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.
Volume: 64
Issue: 6
Pages: 1023-1034
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Publication
21795692 | J:184110
First Author: Verpelli C
Year: 2011
Journal: J Biol Chem
Title: Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.
Volume: 286
Issue: 40
Pages: 34839-50
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Publication
25838543 | J:221584
First Author: Quesnel-Vallières M
Year: 2015
Journal: Genes Dev
Title: Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.
Volume: 29
Issue: 7
Pages: 746-59
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Publication
36460641 | J:332132
First Author: Cattaneo P
Year: 2022
Journal: Nat Commun
Title: DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal.
Volume: 13
Issue: 1
Pages: 7444
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Publication
19208628 | J:148808
First Author: Sawallisch C
Year: 2009
Journal: J Biol Chem
Title: The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.
Volume: 284
Issue: 14
Pages: 9225-36
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Publication
32492419 | J:306456
First Author: Farini D
Year: 2020
Journal: Cell Rep
Title: A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.
Volume: 31
Issue: 9
Pages: 107703
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Publication
15033168 | J:107647
First Author: Thuret S
Year: 2004
Journal: Mol Cell Neurosci
Title: Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.
Volume: 25
Issue: 3
Pages: 394-405
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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