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Search results 1 to 100 out of 248 for Shank3

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0.041s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Han K
Year: 2013
Journal: Nature
Title: SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties.
Volume: 503
Issue: 7474
Pages: 72-7
Publication
First Author: Lee Y
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Characterization of the zinc-induced Shank3 interactome of mouse synaptosome.
Volume: 494
Issue: 3-4
Pages: 581-586
Publication      
First Author: Worley P
Year: 2013
Journal: MGI Direct Data Submission
Title: Haploinsufficiency of Shank3 causes Autism-like phenotypes in mice
Publication    
First Author: Ingiosi AM
Year: 2019
Journal: Elife
Title: Shank3 modulates sleep and expression of circadian transcription factors.
Volume: 8
Publication
First Author: Bidinosti M
Year: 2016
Journal: Science
Title: CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.
Volume: 351
Issue: 6278
Pages: 1199-203
Publication
First Author: Mei Y
Year: 2016
Journal: Nature
Title: Adult restoration of Shank3 expression rescues selective autistic-like phenotypes.
Volume: 530
Issue: 7591
Pages: 481-4
Publication  
First Author: Lee Y
Year: 2017
Journal: Front Mol Neurosci
Title: Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations.
Volume: 10
Pages: 110
Publication  
First Author: Lee Y
Year: 2017
Journal: Front Mol Neurosci
Title: Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling.
Volume: 10
Pages: 201
Publication
First Author: Peça J
Year: 2011
Journal: Nature
Title: Shank3 mutant mice display autistic-like behaviours and striatal dysfunction.
Volume: 472
Issue: 7344
Pages: 437-42
Publication
First Author: Yi F
Year: 2016
Journal: Science
Title: Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons.
Volume: 352
Issue: 6286
Pages: aaf2669
Publication
First Author: Wang L
Year: 2020
Journal: Mol Psychiatry
Title: An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function.
Volume: 25
Issue: 10
Pages: 2534-2555
Publication
First Author: Jin C
Year: 2019
Journal: J Neurochem
Title: Shank3 regulates striatal synaptic abundance of Cyld, a deubiquitinase specific for Lys63-linked polyubiquitin chains.
Volume: 150
Issue: 6
Pages: 776-786
Publication
First Author: Tatavarty V
Year: 2020
Journal: Neuron
Title: Autism-Associated Shank3 Is Essential for Homeostatic Compensation in Rodent V1.
Volume: 106
Issue: 5
Pages: 769-777.e4
Publication
First Author: Guo B
Year: 2019
Journal: Nat Neurosci
Title: Anterior cingulate cortex dysfunction underlies social deficits in Shank3 mutant mice.
Volume: 22
Issue: 8
Pages: 1223-1234
Publication
First Author: Bariselli S
Year: 2016
Journal: Nat Neurosci
Title: SHANK3 controls maturation of social reward circuits in the VTA.
Volume: 19
Issue: 7
Pages: 926-934
Publication  
First Author: Chiesa M
Year: 2019
Journal: Neural Plast
Title: Enhanced Glutamatergic Currents at Birth in Shank3 KO Mice.
Volume: 2019
Pages: 2382639
Publication
First Author: Pagani M
Year: 2019
Journal: J Neurosci
Title: Deletion of Autism Risk Gene Shank3 Disrupts Prefrontal Connectivity.
Volume: 39
Issue: 27
Pages: 5299-5310
Publication
First Author: Kouser M
Year: 2013
Journal: J Neurosci
Title: Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission.
Volume: 33
Issue: 47
Pages: 18448-68
Publication
First Author: Jaramillo TC
Year: 2017
Journal: Autism Res
Title: Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function.
Volume: 10
Issue: 1
Pages: 42-65
Publication
First Author: Lin R
Year: 2021
Journal: Cell Rep
Title: Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome.
Volume: 37
Issue: 7
Pages: 110014
Publication
First Author: Han Q
Year: 2016
Journal: Neuron
Title: SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons.
Volume: 92
Issue: 6
Pages: 1279-1293
Publication
First Author: Vicidomini C
Year: 2017
Journal: Mol Psychiatry
Title: Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice.
Volume: 22
Issue: 5
Pages: 689-702
Publication  
First Author: Lutz AK
Year: 2020
Journal: Sci Transl Med
Title: Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles.
Volume: 12
Issue: 547
Publication
First Author: Sarowar T
Year: 2016
Journal: J Neurochem
Title: Activity and circadian rhythm influence synaptic Shank3 protein levels in mice.
Volume: 138
Issue: 6
Pages: 887-95
Publication  
First Author: Otazu GH
Year: 2021
Journal: Neurosci Lett
Title: Neurodevelopmental malformations of the cerebellum and neocortex in the Shank3 and Cntnap2 mouse models of autism.
Volume: 765
Pages: 136257
Publication
First Author: Zhou Y
Year: 2016
Journal: Neuron
Title: Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.
Volume: 89
Issue: 1
Pages: 147-62
Publication
First Author: Chen Q
Year: 2020
Journal: Nat Neurosci
Title: Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD.
Volume: 23
Issue: 4
Pages: 520-532
Publication
First Author: Waga C
Year: 2014
Journal: J Neurochem
Title: Identification of two novel Shank3 transcripts in the developing mouse neocortex.
Volume: 128
Issue: 2
Pages: 280-93
Publication  
First Author: Wang X
Year: 2016
Journal: Nat Commun
Title: Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.
Volume: 7
Pages: 11459
Publication
First Author: Speed HE
Year: 2015
Journal: J Neurosci
Title: Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits.
Volume: 35
Issue: 26
Pages: 9648-65
Publication
First Author: Jaramillo TC
Year: 2016
Journal: Autism Res
Title: Altered Striatal Synaptic Function and Abnormal Behaviour in Shank3 Exon4-9 Deletion Mouse Model of Autism.
Volume: 9
Issue: 3
Pages: 350-75
Publication
First Author: Yang M
Year: 2012
Journal: J Neurosci
Title: Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice.
Volume: 32
Issue: 19
Pages: 6525-41
Publication  
First Author: Sauer AK
Year: 2019
Journal: Int J Mol Sci
Title: Altered Intestinal Morphology and Microbiota Composition in the Autism Spectrum Disorders Associated SHANK3 Mouse Model.
Volume: 20
Issue: 9
GXD Expression      
Probe: MGI:6183244
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191298
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Shank3
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6183244
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191298
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Shank3
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6183244
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191298
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Shank3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6183244
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191298
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Shank3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6183244
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191298
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Shank3
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6183244
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191298
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Shank3
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6183244
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191298
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Shank3
Detected: true
Specimen Num: 7
Publication
First Author: Kabitzke PA
Year: 2018
Journal: Genes Brain Behav
Title: Comprehensive analysis of two Shank3 and the Cacna1c mouse models of autism spectrum disorder.
Volume: 17
Issue: 1
Pages: 4-22
Publication
First Author: Uchino S
Year: 2006
Journal: J Neurochem
Title: Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.
Volume: 97
Issue: 4
Pages: 1203-14
Publication
First Author: Verpelli C
Year: 2011
Journal: J Biol Chem
Title: Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.
Volume: 286
Issue: 40
Pages: 34839-50
Publication
First Author: Schuetz G
Year: 2004
Journal: J Cell Biol
Title: The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
Volume: 167
Issue: 5
Pages: 945-52
Publication  
First Author: Cope EC
Year: 2016
Journal: eNeuro
Title: Immature Neurons and Radial Glia, But Not Astrocytes or Microglia, Are Altered in Adult Cntnap2 and Shank3 Mice, Models of Autism.
Volume: 3
Issue: 5
Publication
First Author: Bey AL
Year: 2018
Journal: Transl Psychiatry
Title: Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors.
Volume: 8
Issue: 1
Pages: 94
Publication
First Author: Bozdagi O
Year: 2010
Journal: Mol Autism
Title: Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication.
Volume: 1
Issue: 1
Pages: 15
Publication  
First Author: Jin C
Year: 2019
Journal: Front Mol Neurosci
Title: Unexpected Compensatory Increase in Shank3 Transcripts in Shank3 Knock-Out Mice Having Partial Deletions of Exons.
Volume: 12
Pages: 228
Publication  
First Author: Torossian A
Year: 2021
Journal: Neurobiol Dis
Title: Increased rates of cerebral protein synthesis in Shank3 knockout mice: Implications for a link between synaptic protein deficit and dysregulated protein synthesis in autism spectrum disorder/intellectual disability.
Volume: 148
Pages: 105213
Publication
First Author: Amal H
Year: 2020
Journal: Mol Psychiatry
Title: Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function.
Volume: 25
Issue: 8
Pages: 1835-1848
Publication  
First Author: Jaramillo TC
Year: 2020
Journal: eNeuro
Title: Early Restoration of Shank3 Expression in Shank3 Knock-Out Mice Prevents Core ASD-Like Behavioral Phenotypes.
Volume: 7
Issue: 3
Publication  
First Author: Speed HE
Year: 2019
Journal: eNeuro
Title: Apparent Genetic Rescue of Adult Shank3 Exon 21 Insertion Mutation Mice Tempered by Appropriate Control Experiments.
Volume: 6
Issue: 5
Publication  
First Author: Fourie C
Year: 2018
Journal: Front Cell Neurosci
Title: Dietary Zinc Supplementation Prevents Autism Related Behaviors and Striatal Synaptic Dysfunction in Shank3 Exon 13-16 Mutant Mice.
Volume: 12
Pages: 374
Publication  
First Author: Schoen M
Year: 2019
Journal: Front Neural Circuits
Title: Shank3 Transgenic and Prenatal Zinc-Deficient Autism Mouse Models Show Convergent and Individual Alterations of Brain Structures in MRI.
Volume: 13
Pages: 6
Publication
First Author: Jin C
Year: 2021
Journal: Mol Brain
Title: Increased ribosomal protein levels and protein synthesis in the striatal synaptosome of Shank3-overexpressing transgenic mice.
Volume: 14
Issue: 1
Pages: 39
Publication  
First Author: Drapeau E
Year: 2018
Journal: eNeuro
Title: Behavioral Phenotyping of an Improved Mouse Model of Phelan-McDermid Syndrome with a Complete Deletion of the Shank3 Gene.
Volume: 5
Issue: 3
Publication  
First Author: Yoo T
Year: 2018
Journal: Front Cell Neurosci
Title: GABA Neuronal Deletion of Shank3 Exons 14-16 in Mice Suppresses Striatal Excitatory Synaptic Input and Induces Social and Locomotor Abnormalities.
Volume: 12
Pages: 341
Publication  
First Author: Lee B
Year: 2017
Journal: Neurosci Lett
Title: Age-dependent decrease of GAD65/67 mRNAs but normal densities of GABAergic interneurons in the brain regions of Shank3-overexpressing manic mouse model.
Volume: 649
Pages: 48-54
Publication  
First Author: Jin C
Year: 2018
Journal: Front Mol Neurosci
Title: Integrative Brain Transcriptome Analysis Reveals Region-Specific and Broad Molecular Changes in Shank3-Overexpressing Mice.
Volume: 11
Pages: 250
Publication  
First Author: Yoo YE
Year: 2019
Journal: Front Mol Neurosci
Title: Shank3 Mice Carrying the Human Q321R Mutation Display Enhanced Self-Grooming, Abnormal Electroencephalogram Patterns, and Suppressed Neuronal Excitability and Seizure Susceptibility.
Volume: 12
Pages: 155
Publication  
First Author: Reim D
Year: 2017
Journal: Front Mol Neurosci
Title: Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder.
Volume: 10
Pages: 26
Publication  
First Author: Yoo T
Year: 2019
Journal: Front Cell Neurosci
Title: Shank3 Exons 14-16 Deletion in Glutamatergic Neurons Leads to Social and Repetitive Behavioral Deficits Associated With Increased Cortical Layer 2/3 Neuronal Excitability.
Volume: 13
Pages: 458
Publication
First Author: Duffney LJ
Year: 2015
Journal: Cell Rep
Title: Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators.
Volume: 11
Issue: 9
Pages: 1400-1413
Publication
First Author: Lee DK
Year: 2021
Journal: Nat Neurosci
Title: Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time.
Volume: 24
Issue: 9
Pages: 1243-1255
Publication
First Author: Orefice LL
Year: 2019
Journal: Cell
Title: Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models.
Volume: 178
Issue: 4
Pages: 867-886.e24
Publication
First Author: Lilja J
Year: 2017
Journal: Nat Cell Biol
Title: SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras.
Volume: 19
Issue: 4
Pages: 292-305
Publication
First Author: Qin L
Year: 2018
Journal: Nat Neurosci
Title: Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition.
Volume: 21
Issue: 4
Pages: 564-575
Publication
First Author: Peixoto RT
Year: 2016
Journal: Nat Neurosci
Title: Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B(-/-) mice.
Volume: 19
Issue: 5
Pages: 716-24
Publication
First Author: Peixoto RT
Year: 2019
Journal: Cell Rep
Title: Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B-/- Mice.
Volume: 29
Issue: 7
Pages: 2016-2027.e4
Publication
First Author: Kazdoba TM
Year: 2016
Journal: Genes Brain Behav
Title: Behavioral phenotypes of genetic mouse models of autism.
Volume: 15
Issue: 1
Pages: 7-26
Publication
First Author: de la Torre-Ubieta L
Year: 2016
Journal: Nat Med
Title: Advancing the understanding of autism disease mechanisms through genetics.
Volume: 22
Issue: 4
Pages: 345-61
Publication  
First Author: Lee J
Year: 2015
Journal: Front Cell Neurosci
Title: Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit.
Volume: 9
Pages: 94
Publication
First Author: Wang W
Year: 2017
Journal: J Clin Invest
Title: Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism.
Volume: 127
Issue: 5
Pages: 1978-1990
Publication  
First Author: Cai G
Year: 2019
Journal: Front Psychiatry
Title: Brain mGluR5 in Shank3B-/- Mice Studied With in vivo [18F]FPEB PET Imaging and ex vivo Immunoblotting.
Volume: 10
Pages: 38
Publication
First Author: Vyas Y
Year: 2020
Journal: Mol Brain
Title: Influence of maternal zinc supplementation on the development of autism-associated behavioural and synaptic deficits in offspring Shank3-knockout mice.
Volume: 13
Issue: 1
Pages: 110
Publication
First Author: Wong BKY
Year: 2019
Journal: PLoS One
Title: Maternal stress in Shank3ex4-9 mice increases pup-directed care and alters brain white matter in male offspring.
Volume: 14
Issue: 11
Pages: e0224876
Publication
First Author: Drapeau E
Year: 2014
Journal: Dis Model Mech
Title: Absence of strong strain effects in behavioral analyses of Shank3-deficient mice.
Volume: 7
Issue: 6
Pages: 667-81
Publication  
First Author: Pfaender S
Year: 2017
Journal: Sci Rep
Title: Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3.
Volume: 7
Pages: 45190
Publication
First Author: Jin C
Year: 2018
Journal: Mol Brain
Title: Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus.
Volume: 11
Issue: 1
Pages: 71
Publication
First Author: Jin C
Year: 2018
Journal: Mol Brain
Title: Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background.
Volume: 11
Issue: 1
Pages: 57
Publication  
First Author: Copping NA
Year: 2017
Journal: Neuroscience
Title: Touchscreen learning deficits and normal social approach behavior in the Shank3B model of Phelan-McDermid Syndrome and autism.
Volume: 345
Pages: 155-165
Publication  
First Author: Xu Y
Year: 2022
Journal: Front Cell Neurosci
Title: Expression of SH3 and Multiple Ankyrin Repeat Domains Protein 3 in Mouse Retina.
Volume: 16
Pages: 795668
Publication
First Author: Han KA
Year: 2020
Journal: Mol Autism
Title: Differentially altered social dominance- and cooperative-like behaviors in Shank2- and Shank3-mutant mice.
Volume: 11
Issue: 1
Pages: 87
Publication
First Author: Raynaud F
Year: 2013
Journal: J Neurosci
Title: Shank3-Rich2 interaction regulates AMPA receptor recycling and synaptic long-term potentiation.
Volume: 33
Issue: 23
Pages: 9699-715
Publication  
First Author: Horder J
Year: 2018
Journal: Sci Transl Med
Title: GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models.
Volume: 10
Issue: 461
Publication
First Author: Perfitt TL
Year: 2020
Journal: J Neurosci
Title: Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction.
Volume: 40
Issue: 10
Pages: 2000-2014
Publication  
First Author: Heise C
Year: 2018
Journal: Front Mol Neurosci
Title: Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models.
Volume: 11
Pages: 212
Publication
First Author: Wang X
Year: 2011
Journal: Hum Mol Genet
Title: Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.
Volume: 20
Issue: 15
Pages: 3093-108
Publication  
First Author: Sarowar T
Year: 2016
Journal: Mol Brain
Title: Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.
Volume: 9
Pages: 28
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus