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Search results 1 to 100 out of 231 for Skp2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Latres E
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Role of the F-box protein Skp2 in lymphomagenesis.
Volume: 98
Issue: 5
Pages: 2515-20
Publication
First Author: Agarwal A
Year: 2008
Journal: Blood
Title: Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease.
Volume: 112
Issue: 5
Pages: 1960-70
Publication
First Author: Lin HK
Year: 2010
Journal: Nature
Title: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.
Volume: 464
Issue: 7287
Pages: 374-9
Publication
First Author: Rodriguez S
Year: 2020
Journal: Leukemia
Title: Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL.
Volume: 34
Issue: 5
Pages: 1241-1252
Publication
First Author: Sakai T
Year: 2007
Journal: J Biol Chem
Title: Skp2 controls adipocyte proliferation during the development of obesity.
Volume: 282
Issue: 3
Pages: 2038-46
Publication
First Author: Thacker G
Year: 2016
Journal: Biochim Biophys Acta
Title: Skp2 inhibits osteogenesis by promoting ubiquitin-proteasome degradation of Runx2.
Volume: 1863
Issue: 4
Pages: 510-9
Publication  
First Author: Lu Z
Year: 2014
Journal: Nat Commun
Title: Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity.
Volume: 5
Pages: 3463
Publication
First Author: Sistrunk C
Year: 2013
Journal: Am J Pathol
Title: Skp2 deficiency inhibits chemical skin tumorigenesis independent of p27(Kip1) accumulation.
Volume: 182
Issue: 5
Pages: 1854-64
Publication
First Author: Huang H
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation.
Volume: 102
Issue: 5
Pages: 1649-54
Publication
First Author: Gao D
Year: 2009
Journal: Nat Cell Biol
Title: Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction.
Volume: 11
Issue: 4
Pages: 397-408
Publication
First Author: Wu J
Year: 2012
Journal: Mol Cell
Title: Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1.
Volume: 46
Issue: 3
Pages: 351-61
Publication
First Author: Kotoshiba S
Year: 2014
Journal: Biochim Biophys Acta
Title: p27 is regulated independently of Skp2 in the absence of Cdk2.
Volume: 1843
Issue: 2
Pages: 436-45
Publication
First Author: Wang J
Year: 2011
Journal: Blood
Title: The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal.
Volume: 118
Issue: 20
Pages: 5429-38
Publication
First Author: Ruan D
Year: 2017
Journal: Oncogene
Title: Skp2 deficiency restricts the progression and stem cell features of castration-resistant prostate cancer by destabilizing Twist.
Volume: 36
Issue: 30
Pages: 4299-4310
Publication
First Author: Li Z
Year: 2019
Journal: J Biol Chem
Title: A novel thyroid hormone receptor isoform, TRβ2-46, promotes SKP2 expression and retinoblastoma cell proliferation.
Volume: 294
Issue: 8
Pages: 2961-2969
Publication
First Author: Delogu S
Year: 2015
Journal: Oncotarget
Title: SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice.
Volume: 6
Issue: 4
Pages: 2222-34
Publication
First Author: Okada M
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Skp2 promotes adipocyte differentiation via a p27Kip1-independent mechanism in primary mouse embryonic fibroblasts.
Volume: 379
Issue: 2
Pages: 249-54
Publication
First Author: Lu W
Year: 2017
Journal: Oncogene
Title: SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer.
Volume: 36
Issue: 10
Pages: 1364-1373
Publication
First Author: Wang H
Year: 2010
Journal: Nat Genet
Title: Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice.
Volume: 42
Issue: 1
Pages: 83-8
Publication
First Author: Dong Y
Year: 2003
Journal: Neuroreport
Title: Role of the F-box protein Skp2 in cell proliferation in the developing auditory system in mice.
Volume: 14
Issue: 5
Pages: 759-61
Publication
First Author: Sarmento LM
Year: 2005
Journal: J Exp Med
Title: Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation.
Volume: 202
Issue: 1
Pages: 157-68
Publication
First Author: Nakayama K
Year: 2000
Journal: EMBO J
Title: Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.
Volume: 19
Issue: 9
Pages: 2069-81
Publication
First Author: Wang J
Year: 2014
Journal: Biochem Biophys Res Commun
Title: E3-ligase Skp2 regulates β-catenin expression and maintains hematopoietic stem cell homing.
Volume: 445
Issue: 3
Pages: 566-71
Publication
First Author: Lin HK
Year: 2009
Journal: Nat Cell Biol
Title: Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.
Volume: 11
Issue: 4
Pages: 420-32
Publication
First Author: Old JB
Year: 2010
Journal: Mol Cancer Res
Title: Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.
Volume: 8
Issue: 3
Pages: 353-62
Publication
First Author: Wang S
Year: 2010
Journal: Mol Cancer Res
Title: STAT1 represses Skp2 gene transcription to promote p27Kip1 stabilization in Ras-transformed cells.
Volume: 8
Issue: 5
Pages: 798-805
Publication
First Author: Nogueira V
Year: 2012
Journal: EMBO J
Title: Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis.
Volume: 31
Issue: 5
Pages: 1134-46
Publication
First Author: Yamauchi Y
Year: 2020
Journal: Genes Cells
Title: Skp2 contributes to cell cycle progression in trophoblast stem cells and to placental development.
Volume: 25
Issue: 6
Pages: 427-438
Publication
First Author: Su H
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: MAD2B contributes to podocyte injury of diabetic nephropathy via inducing cyclin B1 and Skp2 accumulation.
Volume: 308
Issue: 7
Pages: F728-36
Publication
First Author: Hulit J
Year: 2006
Journal: Cancer Res
Title: p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.
Volume: 66
Issue: 17
Pages: 8529-41
Publication
First Author: Yoshida K
Year: 2002
Journal: Invest Ophthalmol Vis Sci
Title: Involvement of p27(KIP1) degradation by Skp2 in the regulation of proliferation in response to wounding of corneal epithelium.
Volume: 43
Issue: 2
Pages: 364-70
Publication
First Author: Sistrunk C
Year: 2011
Journal: Am J Pathol
Title: Skp2 is necessary for Myc-induced keratinocyte proliferation but dispensable for Myc oncogenic activity in the oral epithelium.
Volume: 178
Issue: 6
Pages: 2470-7
Publication
First Author: Li X
Year: 2015
Journal: Oncotarget
Title: Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model.
Volume: 6
Issue: 39
Pages: 41809-24
Publication
First Author: Song GJ
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: The scaffolding protein EBP50 promotes vascular smooth muscle cell proliferation and neointima formation by regulating Skp2 and p21(cip1).
Volume: 32
Issue: 1
Pages: 33-41
Publication
First Author: Zhao H
Year: 2013
Journal: Cancer Cell
Title: Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors.
Volume: 24
Issue: 5
Pages: 645-59
Publication
First Author: Minamishima YA
Year: 2002
Journal: Cancer Res
Title: Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient mice.
Volume: 62
Issue: 4
Pages: 995-9
Publication
First Author: Chan CH
Year: 2012
Journal: Cell
Title: The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.
Volume: 149
Issue: 5
Pages: 1098-111
Publication
First Author: Wu YJ
Year: 2009
Journal: J Vasc Surg
Title: S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo.
Volume: 50
Issue: 5
Pages: 1135-42
Publication
First Author: Jiang X
Year: 2009
Journal: Mol Cell Biol
Title: Mechanoregulation of proliferation.
Volume: 29
Issue: 18
Pages: 5104-14
Publication
First Author: Wang D
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of S-phase kinase-associated protein 2 (Skp2) reprograms and converts diabetogenic T cells to Foxp3+ regulatory T cells.
Volume: 109
Issue: 24
Pages: 9493-8
Publication
First Author: Kossatz U
Year: 2004
Journal: Genes Dev
Title: Skp2-dependent degradation of p27kip1 is essential for cell cycle progression.
Volume: 18
Issue: 21
Pages: 2602-7
Publication
First Author: Harmey D
Year: 2009
Journal: J Biol Chem
Title: The anaphase promoting complex induces substrate degradation during neuronal differentiation.
Volume: 284
Issue: 7
Pages: 4317-23
Publication
First Author: Nakayama K
Year: 2004
Journal: Dev Cell
Title: Skp2-mediated degradation of p27 regulates progression into mitosis.
Volume: 6
Issue: 5
Pages: 661-72
Publication
First Author: Spruck C
Year: 2001
Journal: Mol Cell
Title: A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.
Volume: 7
Issue: 3
Pages: 639-50
Publication  
First Author: Xu D
Year: 2015
Journal: Nat Commun
Title: Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis.
Volume: 6
Pages: 6641
Publication
First Author: Zhang L
Year: 2011
Journal: Immunity
Title: Coupling of V(D)J recombination to the cell cycle suppresses genomic instability and lymphoid tumorigenesis.
Volume: 34
Issue: 2
Pages: 163-74
Publication
First Author: Chander H
Year: 2010
Journal: EMBO Rep
Title: Skp2B attenuates p53 function by inhibiting prohibitin.
Volume: 11
Issue: 3
Pages: 220-5
Publication
First Author: Gizard F
Year: 2011
Journal: J Biol Chem
Title: Transcriptional regulation of S phase kinase-associated protein 2 by NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cells.
Volume: 286
Issue: 41
Pages: 35485-93
Publication
First Author: Timmerbeul I
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer.
Volume: 103
Issue: 38
Pages: 14009-14
Publication
First Author: Castagnino P
Year: 2013
Journal: PLoS One
Title: miR-221/222 compensates for Skp2-mediated p27 degradation and is a primary target of cell cycle regulation by prostacyclin and cAMP.
Volume: 8
Issue: 2
Pages: e56140
Publication
First Author: Suzuki S
Year: 2007
Journal: Am J Pathol
Title: Renal damage in obstructive nephropathy is decreased in Skp2-deficient mice.
Volume: 171
Issue: 2
Pages: 473-83
Publication
First Author: Bargagna-Mohan P
Year: 2012
Journal: J Biol Chem
Title: Corneal antifibrotic switch identified in genetic and pharmacological deficiency of vimentin.
Volume: 287
Issue: 2
Pages: 989-1006
Publication
First Author: Kopsiaftis S
Year: 2016
Journal: Mol Cancer Res
Title: AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27.
Volume: 14
Issue: 12
Pages: 1182-1194
Publication
First Author: Zhang S
Year: 2017
Journal: Cancer Cell
Title: Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.
Volume: 31
Issue: 5
Pages: 669-684.e7
Publication
First Author: Chen YT
Year: 2018
Journal: J Immunol
Title: B Cell Development sans B Cell Receptor Responsiveness Due to Unfolded Protein Response-Triggered Mef2c Protein Degradation.
Volume: 201
Issue: 10
Pages: 2885-2898
Publication
First Author: Zuo T
Year: 2007
Journal: J Clin Invest
Title: FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.
Volume: 117
Issue: 12
Pages: 3765-73
Publication
First Author: Villanueva J
Year: 2007
Journal: Mol Biol Cell
Title: ERK activity and G1 phase progression: identifying dispensable versus essential activities and primary versus secondary targets.
Volume: 18
Issue: 4
Pages: 1457-63
Publication
First Author: Lanctot AA
Year: 2017
Journal: Cell Rep
Title: Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation.
Volume: 20
Issue: 5
Pages: 1148-1160
Publication
First Author: Swarnalatha M
Year: 2013
Journal: J Cell Sci
Title: Promoter occupancy of MLL1 histone methyltransferase seems to specify the proliferative and apoptotic functions of E2F1 in a tumour microenvironment.
Volume: 126
Issue: Pt 20
Pages: 4636-46
Publication
First Author: Zhao H
Year: 2016
Journal: J Biol Chem
Title: Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis.
Volume: 291
Issue: 19
Pages: 10201-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ecker K
Year: 2009
Journal: Nat Cell Biol
Title: Skp2: caught in the Akt.
Volume: 11
Issue: 4
Pages: 377-9
Publication
First Author: Iwahara T
Year: 2012
Journal: Mol Cell Biol
Title: SIRT3 functions in the nucleus in the control of stress-related gene expression.
Volume: 32
Issue: 24
Pages: 5022-34
GXD Expression    
Probe: MGI:7562573
Assay Type: RT-PCR
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7562571
Age: embryonic day 13.5
Image: 6
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7562573
Assay Type: RT-PCR
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7562571
Age: embryonic day 15.5
Image: 6
Specimen Label: E15.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7562573
Assay Type: RT-PCR
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7562571
Age: embryonic day 17.5
Image: 6
Specimen Label: E17.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7562576
Age: embryonic day 13.5
Image: 6
Specimen Label: Rb1 E13.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7562576
Age: embryonic day 13.5
Image: 6
Specimen Label: Nes-Cre;Rb1 E13.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7562576
Age: embryonic day 13.5
Image: 6
Specimen Label: Rb1;Skp2-/- E13.5
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7562576
Age: embryonic day 13.5
Image: 6
Specimen Label: Nes-Cre;Rb1;Skp2-/- E13.5
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7562576
Age: embryonic day 15.5
Image: 6
Specimen Label: Rb1 E15.5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7562576
Age: embryonic day 15.5
Image: 6
Specimen Label: Nes-Cre;Rb1 E15.5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7562576
Age: embryonic day 15.5
Image: 6
Specimen Label: Rb1;Skp2-/- E15.5
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7562576
Age: embryonic day 15.5
Image: 6
Specimen Label: Nes-Cre;Rb1;Skp2-/- E15.5
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7562576
Age: embryonic day 17.5
Image: 6
Specimen Label: Rb1 E17.5
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7562576
Age: embryonic day 17.5
Image: 6
Specimen Label: Nes-Cre;Rb1 E17.5
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7562576
Age: embryonic day 17.5
Image: 6
Specimen Label: Rb1;Skp2-/- E17.5
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:7562377
Assay Type: Western blot
Annotation Date: 2023-12-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7562576
Age: embryonic day 17.5
Image: 6
Specimen Label: Nes-Cre;Rb1;Skp2-/- E17.5
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:3585060
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716820
Stage: TS20
Assay Id: MGI:3585958
Age: embryonic day 12.0
Specimen Label: E12
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3585060
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:3585958
Age: embryonic day 14.0
Specimen Label: E14
Detected: false
Specimen Num: 2