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Search results 1 to 100 out of 112 for Slc10a1

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Hits by Strain

Type Details Score
Gene
6554 | SLC10A1
Type: gene
Organism: human
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Gene
100489580 | slc10a1
Type: gene
Organism: frog, western clawed
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Gene
24777 | Slc10a1
Type: gene
Organism: rat
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Gene
480372 | SLC10A1
Type: gene
Organism: dog, domestic
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Gene
453001 | SLC10A1
Type: gene
Organism: chimpanzee
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Gene
532890 | SLC10A1
Type: gene
Organism: cattle
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Gene
562260 | slc10a1
Type: gene
Organism: zebrafish
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Gene
712925 | SLC10A1
Type: gene
Organism: macaque, rhesus
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Gene
101751768 | SLC10A1
Type: gene
Organism: chicken
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Protein Domain
IPR030208 | SLC10A1
Type: Family
Description: Solute carrier family 10 member 1 (SLC10A1), also known as sodium/taurocholate cotransporting polypeptide (NTCP), represents a hepatic sodium/bile acid uptake system that exhibits broad substrate specificity []. NTCP also transports various non-bile acid organic compounds, including steroidal hormones such as estrone-3-sulfate and dehydroepiandrosterone (DHEAS), bromosulphthalein and a variety of xenobiotics []. It also mediates transport of (sulfated) iodothyronines [].
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Protein Coding Gene
MGI:97379 | Slc10a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
8132774 | J:17134
First Author: Hagenbuch B
Year: 1994
Journal: J Clin Invest
Title: Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter.
Volume: 93
Issue: 3
Pages: 1326-31
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Publication
28938430 | J:248002
First Author: Kersseboom S
Year: 2017
Journal: Endocrinology
Title: Role of the Bile Acid Transporter SLC10A1 in Liver Targeting of the Lipid-Lowering Thyroid Hormone Analog Eprotirome.
Volume: 158
Issue: 10
Pages: 3307-3318
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Protein
O08705
Organism: Mus musculus/domesticus
Length: 362  
Fragment?: false
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Protein
A0A1W2P719
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: false
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Protein
Q91XS4
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
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Protein
O35940
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Publication
21103971 | -
 
First Author: Stieger B
Year: 2011
Journal: Handb Exp Pharmacol
Title: The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation.
Issue: 201
Pages: 205-59
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Publication
19682536 | -
First Author: Visser WE
Year: 2010
Journal: Mol Cell Endocrinol
Title: Study of the transport of thyroid hormone by transporters of the SLC10 family.
Volume: 315
Issue: 1-2
Pages: 138-45
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Publication
35937832 | J:327600
 
First Author: Yang F
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: NTCP Deficiency Affects the Levels of Circulating Bile Acids and Induces Osteoporosis.
Volume: 13
Pages: 898750
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Publication
31201272 | J:280390
First Author: Mao F
Year: 2019
Journal: J Biol Chem
Title: Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency.
Volume: 294
Issue: 31
Pages: 11853-11862
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Protein Coding Gene
MGP_CAROLIEiJ_G0017904 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019896 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019829 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019639 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97379 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020285 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019189 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019610 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019750 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018955 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019242 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029660 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018749 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1961729 | J:692
First Author: Hagenbuch B
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system.
Volume: 88
Issue: 23
Pages: 10629-33
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Publication
25641256 | J:274149
First Author: Slijepcevic D
Year: 2015
Journal: Hepatology
Title: Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.
Volume: 62
Issue: 1
Pages: 207-19
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Publication
8769105 | J:34975
First Author: Torchia EC
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Coordinate regulation of bile acid biosynthetic and recovery pathways.
Volume: 225
Issue: 1
Pages: 128-33
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Publication
9657862 | J:48699
First Author: Green RM
Year: 1998
Journal: Mamm Genome
Title: Genetic mapping of the Na(+)-taurocholate cotransporting polypeptide to mouse chromosome 12.
Volume: 9
Issue: 7
Pages: 598
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Publication
10209268 | J:54695
First Author: Cattori V
Year: 1999
Journal: Biochim Biophys Acta
Title: Molecular cloning and functional characterization of two alternatively spliced Ntcp isoforms from mouse liver1.
Volume: 1445
Issue: 1
Pages: 154-9
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Publication
12475240 | J:80749
First Author: Hallén S
Year: 2002
Journal: Biochemistry
Title: Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor.
Volume: 41
Issue: 50
Pages: 14916-24
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Publication
18328802 | J:136734
First Author: Molina H
Year: 2008
Journal: Biochim Biophys Acta
Title: Localization of the Sodium-Taurocholate cotransporting polypeptide in membrane rafts and modulation of its activity by cholesterol in vitro.
Volume: 1778
Issue: 5
Pages: 1283-91
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Publication
26306036 | J:315385
First Author: Sommerfeld A
Year: 2015
Journal: J Biol Chem
Title: Regulation of plasma membrane localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by hyperosmolarity and tauroursodeoxycholate.
Volume: 290
Issue: 40
Pages: 24237-54
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GXD Expression
GXD Expression
   
Probe: MGI:7510215
Assay Type: RT-PCR
Annotation Date: 2023-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7511497
Age: postnatal week 3-4
Image: S4
Specimen Label: Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7510215
Assay Type: RT-PCR
Annotation Date: 2023-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7511497
Age: postnatal week 3-4
Image: S4
Specimen Label: DKO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:7560649
Age: embryonic day 17.5
Specimen Label: -2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7560649
Age: postnatal day 0
Specimen Label: 0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7560649
Age: postnatal day 1
Specimen Label: 1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7560649
Age: postnatal day 3
Specimen Label: 3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560649
Age: postnatal day 5
Specimen Label: 5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560649
Age: postnatal day 10
Specimen Label: 10
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560649
Age: postnatal day 15
Specimen Label: 15
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560649
Age: postnatal day 20
Specimen Label: 20
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560649
Age: postnatal day 25
Specimen Label: 25
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560649
Age: postnatal day 30
Specimen Label: 30
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560649
Age: postnatal day 30
Specimen Label: 45
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:7550678
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560649
Age: postnatal day 60
Specimen Label: 60
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:7614831
Assay Type: RT-PCR
Annotation Date: 2024-03-21
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:7614854
Age: postnatal adult
Specimen Label: oocyte
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7614831
Assay Type: RT-PCR
Annotation Date: 2024-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Stage: TS01
Assay Id: MGI:7614854
Age: embryonic day 0.5
Specimen Label: 1-cell
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7614831
Assay Type: RT-PCR
Annotation Date: 2024-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:7614854
Age: embryonic day 1.0
Specimen Label: 2-cell
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4427258
Assay Type: RNA in situ
Annotation Date: 2011-02-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:4888548
Age: embryonic day 14.5
Image: Table S1
Specimen Label: Table S1
Detected: false
Specimen Num: 1
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Publication
9927146 | J:52503
First Author: Koopen NR
Year: 1999
Journal: J Hepatol
Title: Decreased Na+-dependent taurocholate uptake and low expression of the sinusoidal Na+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice.
Volume: 30
Issue: 1
Pages: 14-21
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Publication
31237863 | J:295423
   
First Author: Donkers JM
Year: 2019
Journal: JCI Insight
Title: NTCP deficiency in mice protects against obesity and hepatosteatosis.
Volume: 5
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Publication
16002565 | J:104772
First Author: Zollner G
Year: 2005
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Volume: 289
Issue: 5
Pages: G798-805
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Publication
18483185 | J:138664
First Author: Geier A
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocyte nuclear factor-4alpha is a central transactivator of the mouse Ntcp gene.
Volume: 295
Issue: 2
Pages: G226-33
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Publication
28498614 | J:273941
First Author: Slijepcevic D
Year: 2017
Journal: Hepatology
Title: Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.
Volume: 66
Issue: 5
Pages: 1631-1643
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Publication
23125159 | J:337164
First Author: Cherrington NJ
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis.
Volume: 304
Issue: 1
Pages: G48-56
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Publication
19882669 | J:156027
First Author: Festing MH
Year: 2009
Journal: Genesis
Title: Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1.
Volume: 47
Issue: 12
Pages: 858-63
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Publication
25896510 | J:222615
First Author: Abe K
Year: 2015
Journal: EMBO J
Title: The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing.
Volume: 34
Issue: 11
Pages: 1523-37
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Publication
11279518 | J:68661
First Author: Shih DQ
Year: 2001
Journal: Nat Genet
Title: Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.
Volume: 27
Issue: 4
Pages: 375-82
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Publication
18703564 | J:142114
First Author: Cheng X
Year: 2008
Journal: Toxicol Sci
Title: Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.
Volume: 106
Issue: 1
Pages: 37-45
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Publication
22454430 | J:185731
First Author: Cui JY
Year: 2012
Journal: Toxicol Sci
Title: RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development.
Volume: 127
Issue: 2
Pages: 592-608
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Publication
27146480 | J:233745
First Author: Ferrell JM
Year: 2016
Journal: J Lipid Res
Title: Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders.
Volume: 57
Issue: 7
Pages: 1144-54
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Publication
26222436 | J:228828
First Author: Hamazaki J
Year: 2015
Journal: PLoS Genet
Title: Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.
Volume: 11
Issue: 7
Pages: e1005401
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Publication
16498401 | J:106993
First Author: Briançon N
Year: 2006
Journal: EMBO J
Title: In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping.
Volume: 25
Issue: 6
Pages: 1253-62
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Publication
11208732 | J:66998
First Author: Lammert F
Year: 2001
Journal: Gastroenterology
Title: Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.
Volume: 120
Issue: 1
Pages: 221-38
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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