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Search results 1 to 100 out of 688 for Sorl1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Lane RF
Year: 2010
Journal: J Neurosci
Title: Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex.
Volume: 30
Issue: 39
Pages: 13110-5
GXD Expression    
Probe: MGI:6184013
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191356
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Sorl1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6184013
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191356
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Sorl1
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6184013
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191356
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Sorl1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6184013
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191356
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Sorl1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6184013
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191356
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Sorl1
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6184013
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191356
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Sorl1
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6184013
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191356
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Sorl1
Detected: true
Specimen Num: 7
Publication      
First Author: Hui D
Year: 2007
Journal: MGI Direct Data Submission
Title: Generation and description of gene trap mutation of Sorl1
Publication
First Author: Schmidt V
Year: 2016
Journal: J Clin Invest
Title: SORLA facilitates insulin receptor signaling in adipocytes and exacerbates obesity.
Volume: 126
Issue: 7
Pages: 2706-20
Publication
First Author: Huang TY
Year: 2016
Journal: J Neurosci
Title: SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein.
Volume: 36
Issue: 30
Pages: 7996-8011
Publication  
First Author: Højland A
Year: 2018
Journal: Behav Brain Res
Title: Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner.
Volume: 348
Pages: 90-100
Publication
First Author: Monti G
Year: 2020
Journal: Mol Neurobiol
Title: SORLA Expression in Synaptic Plexiform Layers of Mouse Retina.
Volume: 57
Issue: 7
Pages: 3106-3117
Publication
First Author: Schmidt V
Year: 2012
Journal: EMBO J
Title: Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease.
Volume: 31
Issue: 1
Pages: 187-200
Publication
First Author: Caglayan S
Year: 2014
Journal: Sci Transl Med
Title: Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation.
Volume: 6
Issue: 223
Pages: 223ra20
Publication
First Author: Na JY
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Sortilin-related receptor 1 interacts with amyloid precursor protein and is activated by 6-shogaol, leading to inhibition of the amyloidogenic pathway.
Volume: 484
Issue: 4
Pages: 890-895
Publication
First Author: Stupack J
Year: 2020
Journal: J Neurosci
Title: Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis.
Volume: 40
Issue: 31
Pages: 5908-5921
Publication
First Author: Huang TY
Year: 2017
Journal: J Exp Med
Title: SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration.
Volume: 214
Issue: 12
Pages: 3669-3685
Publication
First Author: Sasner M
Year: 2024
Journal: Alzheimers Dement
Title: In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Volume: 20
Issue: 7
Pages: 4970-4984
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Geng Z
Year: 2011
Journal: J Biol Chem
Title: Sorting protein-related receptor SorLA controls regulated secretion of glial cell line-derived neurotrophic factor.
Volume: 286
Issue: 48
Pages: 41871-82
Publication
First Author: Andersen OM
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Volume: 102
Issue: 38
Pages: 13461-6
Publication
First Author: Hermans-Borgmeyer I
Year: 1998
Journal: Mech Dev
Title: Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex.
Volume: 70
Issue: 1-2
Pages: 65-76
Publication  
First Author: Hampe W
Year: 2000
Journal: J Cell Sci
Title: Ectodomain shedding, translocation and synthesis of SorLA are stimulated by its ligand head activator.
Volume: 113 Pt 24
Pages: 4475-85
Publication
First Author: Dodson SE
Year: 2008
Journal: J Neurosci
Title: Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease.
Volume: 28
Issue: 48
Pages: 12877-86
Publication
First Author: Dumanis SB
Year: 2015
Journal: J Neurosci
Title: Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain.
Volume: 35
Issue: 37
Pages: 12703-13
Publication
First Author: Capsoni S
Year: 2013
Journal: J Alzheimers Dis
Title: SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease.
Volume: 33
Issue: 2
Pages: 357-71
Publication
First Author: Rohe M
Year: 2008
Journal: J Biol Chem
Title: Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis.
Volume: 283
Issue: 21
Pages: 14826-34
Publication  
First Author: Schmidt V
Year: 2021
Journal: J Cell Biol
Title: SORLA is required for insulin-induced expansion of the adipocyte precursor pool in visceral fat.
Volume: 220
Issue: 12
Publication
First Author: Klinger SC
Year: 2016
Journal: FEBS J
Title: Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells.
Volume: 283
Issue: 13
Pages: 2476-93
Publication
First Author: Jiang M
Year: 2008
Journal: J Clin Invest
Title: Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice.
Volume: 118
Issue: 8
Pages: 2733-46
Publication
First Author: Jiang L
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Deletion of LR11 Attenuates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cell Proliferation With Medial Thickening in Mice.
Volume: 36
Issue: 9
Pages: 1972-9
Publication
First Author: Hirayama S
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Differential expression of LR11 during proliferation and differentiation of cultured neuroblastoma cells.
Volume: 275
Issue: 2
Pages: 365-73
Publication
First Author: Nielsen MS
Year: 2007
Journal: Mol Cell Biol
Title: Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.
Volume: 27
Issue: 19
Pages: 6842-51
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5498392
Age: postnatal adult
Image: 1
Specimen Label: heart
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5498392
Age: postnatal adult
Image: 1
Specimen Label: brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5498392
Age: postnatal adult
Image: 1
Specimen Label: lung
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5498392
Age: postnatal adult
Image: 1
Specimen Label: liver
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5498392
Age: postnatal adult
Image: 1
Specimen Label: muscle
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5498392
Age: postnatal adult
Image: 1
Specimen Label: kidney
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:5498393
Age: embryonic day 7.0
Image: 1
Specimen Label: E7
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:5498393
Age: embryonic day 11.0
Image: 1
Specimen Label: E11
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:5498393
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5498361
Assay Type: Northern blot
Annotation Date: 2013-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:5498393
Age: embryonic day 17.0
Image: 1
Specimen Label: E17
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Stage: TS20
Assay Id: MGI:6753117
Age: embryonic day 12.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Stage: TS20
Assay Id: MGI:6753117
Age: embryonic day 12.5
Specimen Label: PA1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Stage: TS20
Assay Id: MGI:6753117
Age: embryonic day 12.5
Specimen Label: PA2
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:6753117
Age: embryonic day 14.5
Specimen Label: WT
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:6753117
Age: embryonic day 14.5
Specimen Label: PA1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:6753117
Age: embryonic day 14.5
Specimen Label: PA2
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691026
Stage: TS26
Assay Id: MGI:6753117
Age: embryonic day 18.5
Specimen Label: WT
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691026
Stage: TS26
Assay Id: MGI:6753117
Age: embryonic day 18.5
Specimen Label: PA1
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691026
Stage: TS26
Assay Id: MGI:6753117
Age: embryonic day 18.5
Specimen Label: PA2
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Stage: TS20
Assay Id: MGI:6753187
Age: embryonic day 12.5
Specimen Label: PA1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6752587
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Stage: TS20
Assay Id: MGI:6753188
Age: embryonic day 12.5
Specimen Label: PA2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6842424
Assay Type: RT-PCR
Annotation Date: 2021-12-31
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6842459
Age: embryonic day 18.5
Image: 4
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6842424
Assay Type: RT-PCR
Annotation Date: 2021-12-31
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6842459
Age: embryonic day 18.5
Image: 4
Specimen Label: -/-
Detected: true
Specimen Num: 2
GXD Expression        
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7444254
Age: postnatal adult
Specimen Label: Heart
Specimen Num: 1
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7444254
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7444254
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7444254
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7444254
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:7444254
Age: postnatal adult
Specimen Label: Skeletal muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7444254
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 7
GXD Expression        
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Not Specified
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:7444254
Age: postnatal adult
Specimen Label: Testis
Specimen Num: 8
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:7444256
Age: postnatal week 1
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:7444256
Age: postnatal week 2
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:7444256
Age: postnatal week 4
Specimen Label: 4
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1327204
Assay Type: Northern blot
Annotation Date: 2023-03-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691028
Stage: TS28
Assay Id: MGI:7444256
Age: postnatal week 8
Specimen Label: 8
Detected: true
Specimen Num: 4