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Search results 1 to 85 out of 85 for Spink5

0.025s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Galliano MF
Year: 2005
Journal: Genomics
Title: Characterization and expression analysis of the Spink5 gene, the mouse ortholog of the defective gene in Netherton syndrome.
Volume: 85
Issue: 4
Pages: 483-92
Publication
First Author: Yang T
Year: 2004
Journal: Genes Dev
Title: Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice.
Volume: 18
Issue: 19
Pages: 2354-8
Publication
First Author: Hewett DR
Year: 2005
Journal: Hum Mol Genet
Title: Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome.
Volume: 14
Issue: 2
Pages: 335-46
Publication
First Author: Yamasaki K
Year: 2007
Journal: Nat Med
Title: Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea.
Volume: 13
Issue: 8
Pages: 975-80
Publication
First Author: Zingkou E
Year: 2020
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Cathelicidin represents a new target for manipulation of skin inflammation in Netherton syndrome.
Volume: 1866
Issue: 10
Pages: 165831
Publication
First Author: Furio L
Year: 2015
Journal: PLoS Genet
Title: KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome.
Volume: 11
Issue: 9
Pages: e1005389
Publication
First Author: Briot A
Year: 2010
Journal: J Invest Dermatol
Title: Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model.
Volume: 130
Issue: 12
Pages: 2736-42
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication    
First Author: Beutler B
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission
Volume: v
Publication
First Author: Descargues P
Year: 2005
Journal: Nat Genet
Title: Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity.
Volume: 37
Issue: 1
Pages: 56-65
Publication
First Author: Deraison C
Year: 2007
Journal: Mol Biol Cell
Title: LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction.
Volume: 18
Issue: 9
Pages: 3607-19
GXD Expression      
Probe: MGI:3711685
Assay Type: RT-PCR
Annotation Date: 2007-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639223
Stage: TS23
Assay Id: MGI:3711799
Age: embryonic day 15.5
Specimen Label: E15.5 wt
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3711685
Assay Type: RT-PCR
Annotation Date: 2007-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639224
Stage: TS24
Assay Id: MGI:3711799
Age: embryonic day 16.5
Specimen Label: E16.5 wt
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3711685
Assay Type: RT-PCR
Annotation Date: 2007-06-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3639224
Stage: TS24
Assay Id: MGI:3711799
Age: embryonic day 16.5
Specimen Label: E16.5 Klf4-/-
Detected: true
Specimen Num: 3
Publication
First Author: Zingkou E
Year: 2019
Journal: J Dermatol Sci
Title: A proinflammatory role of KLK6 protease in Netherton syndrome.
Volume: 95
Issue: 1
Pages: 28-35
Publication
First Author: Yamasaki K
Year: 2006
Journal: FASEB J
Title: Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin.
Volume: 20
Issue: 12
Pages: 2068-80
Publication
First Author: Bonnart C
Year: 2010
Journal: J Clin Invest
Title: Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing.
Volume: 120
Issue: 3
Pages: 871-82
Publication
First Author: Bautista DM
Year: 2014
Journal: Nat Neurosci
Title: Why we scratch an itch: the molecules, cells and circuits of itch.
Volume: 17
Issue: 2
Pages: 175-82
Publication
First Author: Briot A
Year: 2009
Journal: J Exp Med
Title: Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome.
Volume: 206
Issue: 5
Pages: 1135-47
Publication
First Author: Kasparek P
Year: 2017
Journal: PLoS Genet
Title: KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
Volume: 13
Issue: 1
Pages: e1006566
Publication
First Author: Patel S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition.
Volume: 103
Issue: 49
Pages: 18668-73
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: GemPharmatech
Year: 2020
Journal: website
Title: GemPharmatech website
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Protein
Organism: Mus musculus
Length: 1017  
Fragment?: false
Allele
Name: serine peptidase inhibitor, Kazal type 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: transgene insertion, Alain Hovnanian
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Allele  
Name: serine peptidase inhibitor, Kazal type 5; transposon insertion 1498, Paul A Overbeek
Allele Type: Transposon induced
Allele  
Name: serine peptidase inhibitor, Kazal type 5; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Allele
Name: serine peptidase inhibitor, Kazal type 5; targeted mutation 1, Duncan R Hewett
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: serine peptidase inhibitor, Kazal type 5; targeted mutation 1, Alain Hovnanian
Allele Type: Targeted
Attribute String: Null/knockout
Transgene
Type: transgene
Organism: Mus musculus
Genotype
Symbol: Spink5/Spink5
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Spink5/Spink5
Background: involves: 129P2/OlaHsd * FVB
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Spink5/Spink5
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: F2rl1/F2rl1 Spink5/Spink5
Background: involves: 129P2/OlaHsd * 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Spink5/Spink5
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(IVL-KLK5)#Hov/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
DO Term
Publication
First Author: Hachem JP
Year: 2006
Journal: J Invest Dermatol
Title: Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome.
Volume: 126
Issue: 7
Pages: 1609-21
Publication
First Author: Gouin O
Year: 2020
Journal: J Invest Dermatol
Title: Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature.
Volume: 140
Issue: 6
Pages: 1184-1194
Publication  
First Author: Muzumdar S
Year: 2020
Journal: Dis Model Mech
Title: Genetic activation of Nrf2 reduces cutaneous symptoms in a murine model of Netherton syndrome.
Volume: 13
Issue: 5