Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615199 |
Assay Type: |
RT-PCR |
Annotation Date: |
2006-03-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:3616603 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
RT-PCR E13.5 brain |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615199 |
Assay Type: |
RT-PCR |
Annotation Date: |
2006-03-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3616603 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
RT-PCR P0 brain |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1665821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3617208 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691621 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3617208 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691627 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
Note: |
Authors indicate that there was either ubiquitous or background expression. |
Specimen Label: |
P0 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760621 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3617208 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760627 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
|
Specimen Label: |
P0 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754921 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3617208 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754927 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
Note: |
Authors indicate that there was either ubiquitous or background expression. |
Specimen Label: |
P0 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697427 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
Note: |
Authors indicate that there was either ubiquitous or background expression. |
Specimen Label: |
P0 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716821 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3617208 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716827 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
|
Specimen Label: |
P0 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753627 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
Note: |
Authors indicate that there was either ubiquitous or background expression. |
Specimen Label: |
P0 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3617208 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
Note: |
Expression was detected in precortical tissue. |
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754427 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
|
Specimen Label: |
P0 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284527 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
|
Specimen Label: |
P0 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679727 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
Note: |
Authors indicate that there was either ubiquitous or background expression. |
Specimen Label: |
P0 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754027 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
Note: |
Authors indicate that there was either ubiquitous or background expression. |
Specimen Label: |
P0 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280927 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
Note: |
Authors indicate that there was either ubiquitous or background expression. |
Specimen Label: |
P0 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267921 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3617208 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757721 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:3617208 |
Age: |
embryonic day 13.5 |
Image: |
E13.5 |
|
Specimen Label: |
E13.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3615964 |
Assay Type: |
RNA in situ |
Annotation Date: |
2006-03-21 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757727 |
|
Stage: |
TS27 |
Assay Id: |
MGI:3617208 |
Age: |
postnatal day 0 |
Image: |
P0 |
|
Specimen Label: |
P0 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Publication |
First Author: |
Thuret S |
Year: |
2004 |
Journal: |
Mol Cell Neurosci |
Title: |
Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta. |
Volume: |
25 |
Issue: |
3 |
Pages: |
394-405 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKee AE |
Year: |
2005 |
Journal: |
BMC Dev Biol |
Title: |
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. |
Volume: |
5 |
|
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Haiming Tang, Dustin Ebert, Matthias Blum, Robert Finn, Paul Thomas |
Year: |
2023 |
|
Title: |
TreeGrafter-generated GO annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2012 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Function or Process or Component Unknown following Literature Review |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
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Title: |
MGI Sequence Curation Reference |
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Solis AS |
Year: |
2010 |
Journal: |
RNA Biol |
Title: |
Analysis of SRrp86-regulated alternative splicing: control of c-Jun and IκBβ activity. |
Volume: |
7 |
Issue: |
4 |
Pages: |
486-94 |
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Publication |
First Author: |
Barnard DC |
Year: |
2002 |
Journal: |
RNA |
Title: |
Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins. |
Volume: |
8 |
Issue: |
4 |
Pages: |
526-33 |
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Publication |
First Author: |
Li J |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
A unique glutamic acid-lysine (EK) domain acts as a splicing inhibitor. |
Volume: |
277 |
Issue: |
42 |
Pages: |
39485-92 |
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Protein Domain |
Type: |
Domain |
Description: |
This entry represents the RNA recognition motif 2 (RRM2) of SREK1 (also known as SRrp86). SREK1 belongs to a family of proteins containing regions rich in serine-arginine dipeptides (SR proteins family), which is involved in bridge-complex formation and splicing by mediating protein-protein interactions across either introns or exons. It may play a crucial role in determining tissue specific patterns of alternative splicing. SREK1 can alter splice site selection by both positively and negatively modulating the activity of other SR proteins. For instance, SREK1 can activate SRp20 and repress SC35 in a dose-dependent manner both in vitro and in vivo [].SREK1 contains two (some contain only one) RNA recognition motifs (RRMs), and two serine-arginine (SR)-rich domains (SR domains) separated by an unusual glutamic acid-lysine (EK) rich region. The RRM and SR domains are highly conserved among other members of the SR superfamily. However, the EK domain is unique to SREK1. It plays a modulatory role controlling SR domain function by involvement in the inhibition of both constitutive and alternative splicing and in the selection of splice-site [, ]. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
494
|
Fragment?: |
false |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
407
|
Fragment?: |
true |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
198
|
Fragment?: |
false |
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