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Search results 1 to 100 out of 118 for Szt2

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: Szt2 (seizure threshold 2), also known as TIGR (transcript increased in glutamate resistance) is a peroxisomal protein implicated in resistance to oxidative stress. It is not a functional superoxide dismutase (SOD), but might be involved in SOD activity []. In mammals, it may serve an important role in the central nervous system [, ]. Szt2 is part of the KICSTOR complex, which functions in the amino acid-sensing branch of the TORC1 signaling pathway [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Frankel WN
Year: 2009
Journal: Genes Brain Behav
Title: Szt2, a novel gene for seizure threshold in mice.
Volume: 8
Issue: 5
Pages: 568-76
Publication
First Author: Toutzaris D
Year: 2010
Journal: Free Radic Biol Med
Title: A novel giant peroxisomal superoxide dismutase motif-containing protein.
Volume: 48
Issue: 6
Pages: 811-20
Publication
First Author: Wolfson RL
Year: 2017
Journal: Nature
Title: KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
Volume: 543
Issue: 7645
Pages: 438-442
Publication
First Author: Peng M
Year: 2017
Journal: Nature
Title: SZT2 dictates GATOR control of mTORC1 signalling.
Volume: 543
Issue: 7645
Pages: 433-437
Protein
Organism: Mus musculus
Length: 3431  
Fragment?: false
Protein
Organism: Mus musculus
Length: 559  
Fragment?: true
Publication
First Author: Basel-Vanagaite L
Year: 2013
Journal: Am J Hum Genet
Title: Biallelic SZT2 mutations cause infantile encephalopathy with epilepsy and dysmorphic corpus callosum.
Volume: 93
Issue: 3
Pages: 524-9
Protein
Organism: Mus musculus
Length: 1520  
Fragment?: true
Gene
Type: gene
Organism: Homo sapiens
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Kidney
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Lung
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Skeletal muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Spinal cord
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4437753
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437816
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4437753
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437816
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4437757
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437817
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4437757
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437817
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4437758
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437818
Age: postnatal adult
Specimen Label: wild-type
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4437758
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437818
Age: postnatal adult
Specimen Label: Szt2m1Frk
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4437753
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437819
Age: postnatal adult
Specimen Label: Szt2m1Frk/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4437753
Assay Type: RT-PCR
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437819
Age: postnatal adult
Specimen Label: Szt2m1Frk/Szt2m1Frk
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: Gene Trap -/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: Gene Trap +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: Gene Trap +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: ENU -/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: ENU +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437824
Age: postnatal
Specimen Label: ENU +/+
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4437743
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437825
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:4437827
Age: embryonic day 17.5
Specimen Label: e17.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:4437827
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437827
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437827
Age: postnatal day 14
Specimen Label: p14
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437827
Age: postnatal day 21
Specimen Label: p21
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4437742
Assay Type: Northern blot
Annotation Date: 2010-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4437827
Age: postnatal day 70
Specimen Label: p70
Detected: true
Specimen Num: 6
Publication
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
UniProt Feature
Begin: 1
Description: KICSTOR complex protein SZT2
Type: chain
End: 3431
Protein
Organism: Mus musculus
Length: 3430  
Fragment?: false
Allele  
Name: SZT2 subunit of KICSTOR complex; wild type
Allele Type: Not Specified
Allele  
Name: SZT2 subunit of KICSTOR complex; mutation 1, Wayne N Frankel
Allele Type: Chemically induced (ENU)
Allele
Name: SZT2 subunit of KICSTOR complex; gene trap XH662, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
Strain
Attribute String: mutant strain, congenic, chemically induced mutation
Strain
Attribute String: mutant strain, coisogenic, chemically induced mutation
Strain
Attribute String: coisogenic, chemically induced mutation
Strain
Attribute String: gene trap, congenic
Strain
Attribute String: congenic, gene trap